Search Result

Results for "

mammal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (2) Autophagy (2) Bacterial (6) Biochemical Assay Reagents (2) Cytochrome P450 (3) DNA Stain (1) Drug Derivative (1) Drug Metabolite (1) EGFR (1) Endogenous Metabolite (38) Epigenetic Reader Domain (2) Estrogen Receptor/ERR (11) Fluorescent Dye (1) FOXO (1) GABA Receptor (4) Herbicide (3) Insecticide (3) Insulin Receptor (1) Isotope-Labeled Compounds (5) JNK (2) Liposome (3) mTOR (1) NF-κB (2) Parasite (7) PGC-1α (2) Prostaglandin Receptor (4) Sodium Channel (2) TAM Receptor (4) Toll-like Receptor (TLR) (2) γ-secretase (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (3) Endocrinology (3) Infection (14) Inflammation/Immunology (18) Metabolic Disease (22) Neurological Disease (9)
Oligonucleotides:	CpG ODNs (2) Emulsifiers (1) Cholesterol (1)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5807A

Cn2 toxin TFA β-mammal toxin Cn2 TFA	Sodium Channel	Neurological Disease
Cn2 toxin TFA (β-Mammal toxin Cn2 TFA) is a single-chain β-scorpion neurotoxic peptide that is the main toxin in scorpion venom. Cn2 toxin (TFA) specifically targets mammalian voltage-gated sodium channels (VGSC) Nav1.6 .

HY-D2316

Flipper-TR probe	Fluorescent Dye	Others
Flipper-TR probe (Compound FliptR probe) is a fluorescent probe specifically designed to measure cell membrane tension. Flipper-TR probe reports changes in membrane tension through variations in its fluorescence lifetime. Flipper-TR probe is applicable to a wide range of organisms including bacteria, yeast, mammals, and plants .

HY-100196

Pyrroloquinoline quinone 3 Publications Verification PQQ; Methoxatin	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-100196A

Pyrroloquinoline quinone disodium salt 3 Publications Verification PQQ disodium salt; Methoxatin disodium salt	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .

HY-P0241

Neuromedin B 1 Publications Verification	Endogenous Metabolite	Neurological Disease
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.

HY-B2186

Piperazine adipate	Parasite	Infection
Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

HY-123340

Ozolinone	Endogenous Metabolite	Metabolic Disease
Ozolinone is a diuretic metabolite formed by biotransformation of the diuretic elkapin in mammals and exerts a potent diuretic effect in a variety of species .

HY-119360

Lilly 18947 free base	Insecticide	Others
Lilly 18947 (free base) is a selective drug-potentiating agent that synergizes carbamate insecticides. Lilly 18947 (free base) inhibits a variety of detoxication mechanisms in mammals .

HY-P5807

Cn2 toxin β-mammal toxin Cn2	Sodium Channel	Neurological Disease
Cn2 toxin is aβ- toxoins. Cn2 toxin can bind to the voltage sensing domain of voltage gated sodium channels (Na_v) .

HY-110406

13(S)-HPODE	EGFR Endogenous Metabolite	Metabolic Disease
13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.

HY-B2016

Anilofos	Herbicide	Others
Anilofos is a pre-emergence, organophosphorus herbicide. Anilofos has moderate toxic potential in mammals .

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium PQQ-¹³C₃ sodium; Methoxatin-¹³C₃ sodium	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B1217

Bronopol BNPD; BNPK	Bacterial	Infection
Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria).

HY-100196R

Pyrroloquinoline quinone (Standard)	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone (Standard) is the analytical standard of Pyrroloquinoline quinone. This product is intended for research and analytical applications. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-A0058

Retinyl glucoside Retinyl β-D-glucoside	Drug Metabolite	Metabolic Disease
Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.

HY-U00323

Carbazole derivative 1 2-Fluoro-7-[(3-pyridinyl)methyl]-9H-carbazole	Others	Endocrinology
Carbazole derivative 1 is a carbazole derivative which can be used to reduce androgen or oestrogen levels in mammals, including humans.

HY-N10632

Sialyllacto-N-tetraose b	Others	Others
Sialyllacto-N-tetraose b is a sialylated oligosaccharides. Sialyllacto-N-tetraose b naturally occurs in mammal milk .

HY-101988S1

Prostaglandin D2-d9 PGD2-d₉	Prostaglandin Receptor Endogenous Metabolite	Inflammation/Immunology
Prostaglandin D2-d₉ is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

HY-101988S

Prostaglandin D2-d4 PGD2-d₄	Prostaglandin Receptor Endogenous Metabolite	Inflammation/Immunology
Prostaglandin D2-d₄ is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

HY-126199

Tetrachlorvinphos	Endogenous Metabolite	Others
Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .

HY-N2149

Tomatidine 5 Publications Verification	NF-κB JNK Autophagy Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine activates autophagy either in mammal cells or C elegans .

HY-N2149A

Tomatidine hydrochloride 5 Publications Verification	NF-κB JNK Autophagy Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans .

HY-W663938

Cyflumetofen	Parasite	Others
Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi .

HY-P2921

Urate oxidase, Microorganism Uox	Endogenous Metabolite	Others
Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals .

HY-165151

Urobilin hydrochloride Urochrome hydrochloride	Endogenous Metabolite	Others
Urobilin hydrochloride is the metabolite of Hemoglobin (HY-P2995), that can be excreted through urine and feces in many mammals. Urobilin hydrochloride can be used as an indicator of human waste pollution .

HY-B2016R

Anilofos (Standard)	Herbicide	Others
Anilofos (Standard) is the analytical standard of Anilofos. This product is intended for research and analytical applications. Anilofos is a pre-emergence, organophosphorus herbicide. Anilofos has moderate toxic potential in mammals .

HY-148163

Polystyrene sulfonic acid 1 Publications Verification	Biochemical Assay Reagents	Others
Polystyrene sulfonic acid is a potentially toxic hazardous substance. Polystyrene-derived microplastics (PS-MPs) are harmful to zebrafish hearts and induce male reproductive toxicity in mice. MCE offers Polystyrene products in solution packaging .

HY-D1163

Chromium(III) acetate 1 Publications Verification Chromium acetate; Chromic acetate; Chromium triacetate	AMPK	Metabolic Disease
Chromium(III) acetate (Chromic acetate) is an AMPK inhibitor that promotes lipogenesis by inhibiting AMPK phosphorylation. Chromium(III) acetate has low toxicity in mammals, with an LD₅₀ of 2365 mg/kg in rats .

HY-B1217R

Bronopol (Standard)	Bacterial	Infection
Bronopol (Standard) is the analytical standard of Bronopol. This product is intended for research and analytical applications. Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria).

HY-B2186R

Piperazine adipate (Standard)	Parasite	Infection
Piperazine adipate (Standard) is the analytical standard of Piperazine adipate. This product is intended for research and analytical applications. Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

HY-N7387

3-Oxocholic acid	Endogenous Metabolite	Metabolic Disease
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-119779

Pyridalyl S 1812	Insecticide	Others
Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .

HY-121158

Butamifos S-2846	Herbicide	Others
Butamifos (S-2846) is an organophosphoramidate herbicide used to control annual weeds with low toxicity to mammals. Butamifos acts on the growing points of susceptible plants, causing severe radial enlargement of the affected tissues .

HY-B1851

Hexythiazox	Parasite	Infection
Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites .

HY-126199R

Tetrachlorvinphos (Standard)	Endogenous Metabolite	Others
Tetrachlorvinphos (Standard) is the analytical standard of Tetrachlorvinphos. This product is intended for research and analytical applications. Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals .

HY-137219

Δ12(E)-Prostaglandin D2	Drug Derivative	Inflammation/Immunology
Δ12(E)-Prostaglandin D2 is a derivative of Prostaglandin D2 (HY-101988). Prostaglandin D2 is one of the major Prostaglandins actively produced in the brain of various mammals .

HY-157883

C7BzO Dimethyl-2-hydroxyethylampropanepropanesulfonate	Bacterial	Others
C7BzO (Dimethyl-2-hydroxyethylampropanepropanesulfonate) is a potent solubilizing detergent that can be used for samples such as bacteria, mammals, and plants. C7BzO can be used for the extraction of proteins and the preparation of two-dimensional gel electrophoresis samples .

HY-125153A

Bursin triacetate	Others	Endocrinology
Bursin triacetate is a peptide that can be isolated from the bursa of Fabricius in chickens. It promotes the phenotypic differentiation of B precursor cells in both mammals and birds. Bursin triacetate increases cyclic guanosine monophosphate levels in the human B-cell line Daudi .

HY-W663938R

Cyflumetofen (Standard)	Parasite	Others
Cyflumetofen (Standard) is the analytical standard of Cyflumetofen. This product is intended for research and analytical applications. Cyflumetofen is a synthetic miticide that strongly inhibits mitochondrial complex II of spider mites, but not of insects, crustaceans, or mammals. Cyflumetofen is not significantly effective in inhibiting aflatoxin production in fungi .

HY-147578

Axl-IN-11	TAM Receptor	Infection Inflammation/Immunology Cancer
Axl-IN-11 (Example 1) is a potent AXL inhibitor. Axl-IN-11 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancers, viral infectious diseases or other diseases of mammals .

HY-147579

Axl-IN-12	TAM Receptor	Infection Inflammation/Immunology Cancer
Axl-IN-12 (Example 2) is a potent AXL inhibitor. Axl-IN-12 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancers, viral infectious diseases or other diseases of mammals .

HY-101988

Prostaglandin D2 1 Publications Verification PGD2	Prostaglandin Receptor Endogenous Metabolite	Inflammation/Immunology
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .

HY-158012

LY3056480	γ-secretase	Others
LY3056480 is a gamma-secretase inhibitor (GSI) that inhibits Notch signaling. LY3056480 improves mild to moderate sensorineural hearing loss and is safe and tolerable. Intratympanic administration of LY3056480 induces hair cell regeneration and partial hearing recovery in mammals .

HY-B1851S

Hexythiazox-d11	Isotope-Labeled Compounds Parasite	Infection
Hexythiazox-d₁₁ is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites[1][2].

HY-156799

Cholesterol 24-hydroxylase-IN-2	Cytochrome P450	Others
Cholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC₅₀ of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals .

HY-150734

ODN 2007	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .

HY-150734A

ODN 2007 sodium	Toll-like Receptor (TLR)	Infection
ODN 2007 sodium, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 sodium can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .

HY-119779R

Pyridalyl (Standard)	Insecticide	Others
Pyridalyl (Standard) is the analytical standard of Pyridalyl. This product is intended for research and analytical applications. Pyridalyl (S 1812) is an insecticides against Lepidoptera and Thrips. Pyridalyl is less toxic to some beneficial arthropods, and non-target organisms, such as mammals and fish, and thus be utilized in integrated pest management and resistance management .

HY-121158R

Butamifos (Standard)	Others	Others
Butamifos (Standard) is the analytical standard of Butamifos. This product is intended for research and analytical applications. Butamifos (S-2846) is an organophosphoramidate herbicide used to control annual weeds with low toxicity to mammals. Butamifos acts on the growing points of susceptible plants, causing severe radial enlargement of the affected tissues .

HY-100783B

Bicuculline methobromide (+)-Bicuculline methobromide; d-Bicuculline methobromide	GABA Receptor	Neurological Disease
Bicuculline methobromide is a selective GABAA Receptor antagonist with an IC₅₀ value of 3 μM. Bicuculline methobromide induces clonic tonic convulsions in mammals and can also be used to block Ca ²⁺ activated potassium channels. Bicuculline methobromide can be used in studies of epilepsy and other related psychiatric disorders .

Cat. No.	Product Name

HY-L008

JAK/STAT Compound Library

506 compounds

The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more than 30 transmembrane proteins that recognize specific cytokines, and is critical in blood formation and immune response. Canonical JAK/STAT signaling begins with the association of cytokines and their corresponding transmembrane receptors. Activated JAKs then phosphorylate latent STAT monomers, leading to dimerization, nuclear translocation, and DNA binding. In mammals, there are four JAKs (JAK1, JAK2, JAK3, TYK2) and seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, STAT6). Since the JAK/STAT pathway plays a major role in many fundamental processes, such as apoptosis and inflammation, dysfunctional proteins in the pathway may lead to a number of diseases. For example, alterations in JAK/STAT signalling can result in cancer and diseases affecting the immune system, such as severe combined immunodeficiency disorder (SCID).

MCE provides 506 compounds that can be used in the study of the JAK/STAT signaling pathway and related diseases.

Cat. No.	Product Name	Type

HY-D2316

Flipper-TR probe	Fluorescent Dyes/Probes
Flipper-TR probe (Compound FliptR probe) is a fluorescent probe specifically designed to measure cell membrane tension. Flipper-TR probe reports changes in membrane tension through variations in its fluorescence lifetime. Flipper-TR probe is applicable to a wide range of organisms including bacteria, yeast, mammals, and plants .

HY-D0093

Ethidium homodimer

EthD-1

DNA Stain

Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm .

Cat. No.	Product Name	Type

HY-N0322

Cholesterol

Maximum Cited Publications

35 Publications Verification

Drug Delivery

Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-W014971

Tryptamine hydrochloride

1 Publications Verification

Biochemical Assay Reagents

Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries.

HY-N0322A

Cholesterol (Water Soluble)

Maximum Cited Publications

35 Publications Verification

Drug Delivery

Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .

HY-157883

C7BzO Dimethyl-2-hydroxyethylampropanepropanesulfonate	Surfactants
C7BzO (Dimethyl-2-hydroxyethylampropanepropanesulfonate) is a potent solubilizing detergent that can be used for samples such as bacteria, mammals, and plants. C7BzO can be used for the extraction of proteins and the preparation of two-dimensional gel electrophoresis samples .

Cat. No.	Product Name	Target	Research Area

HY-P5807A

Cn2 toxin TFA β-mammal toxin Cn2 TFA	Sodium Channel	Neurological Disease
Cn2 toxin TFA (β-Mammal toxin Cn2 TFA) is a single-chain β-scorpion neurotoxic peptide that is the main toxin in scorpion venom. Cn2 toxin (TFA) specifically targets mammalian voltage-gated sodium channels (VGSC) Nav1.6 .

HY-P0241

Neuromedin B 1 Publications Verification	Endogenous Metabolite	Neurological Disease
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.

HY-P5763

Phoenixin-20 PNX-20	Epigenetic Reader Domain PGC-1α	Neurological Disease
Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect .

HY-P5807

Cn2 toxin β-mammal toxin Cn2	Sodium Channel	Neurological Disease
Cn2 toxin is aβ- toxoins. Cn2 toxin can bind to the voltage sensing domain of voltage gated sodium channels (Na_v) .

HY-P5763A

Phoenixin-20 TFA PNX-20 TFA	Epigenetic Reader Domain PGC-1α	Neurological Disease
Phoenixin-20 (TFA) (PNX-20 (TFA)) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 (TFA) promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 (TFA) has anxiolytic effect .

Cat. No.	Product Name

HY-K6013

Organoid Dissociation Solution
MCE Organoid Dissociation Solution is versatile and suitable for routine dissociation and passaging of organoids derived from various mammals (including humans, mice, pigs, cows, and more).

HY-K6014

Organoid Cryopreservation Medium (Serum Free)
MCE Organoid Cryopreservation Medium (Serum Free) is a ready-to-use cryopreservation medium, widely applicable to organoids and cell lines derived from various mammals (such as human, mouse, pig, cow, etc.).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-100196

Pyrroloquinoline quinone 3 Publications Verification PQQ; Methoxatin	Quinones Structural Classification Microorganisms Animals Classification of Application Fields Source classification Benzene Quinones Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-100196A

Pyrroloquinoline quinone disodium salt 3 Publications Verification PQQ disodium salt; Methoxatin disodium salt	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .

HY-P0241

Neuromedin B 1 Publications Verification	Structural Classification Natural Products Animals Source classification Endogenous metabolite	Endogenous Metabolite
Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.

HY-N2149

Tomatidine 5 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Anti-aging Source classification Pyridine Alkaloids Solanum lycopersicum L. Plants Alkaloids Solanaceae Inflammation/Immunology Disease Research Fields Steroids	NF-κB JNK Autophagy Endogenous Metabolite
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine activates autophagy either in mammal cells or C elegans .

HY-N2149A

Tomatidine hydrochloride 5 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Source classification Solanum lycopersicum L. Solanaceae Plants Disease Research Fields Steroids	NF-κB JNK Autophagy Endogenous Metabolite
Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans .

HY-N7387

3-Oxocholic acid	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
3-Oxocholic acid is an oxo-bile acid metabolite and also a major degradation product from cholic by C. perfringens in the intestine. 3-Oxocholic acid is steroid acid found predominantly in bile of mammals .

HY-101988

Prostaglandin D2 1 Publications Verification PGD2	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .

HY-128749A

D-Glucaric acid tetrahydrate Calcium D-glucarate tetrahydrate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
D-Glucaric acid tetrahydrate is the end-products of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is also found in fruits and vegetables. D-Glucaric acid tetrahydrate can be used to reduce cholesterol and inhibits tumor development. D-Glucaric acid tetrahydrate also enhances human immunity and reduce cancer risks .

HY-110406

13(S)-HPODE	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	EGFR Endogenous Metabolite
13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.

HY-100196R

Pyrroloquinoline quinone (Standard)	Quinones Structural Classification Microorganisms Animals Source classification Benzene Quinones Endogenous metabolite	Endogenous Metabolite
Pyrroloquinoline quinone (Standard) is the analytical standard of Pyrroloquinoline quinone. This product is intended for research and analytical applications. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-W087904

α-Lactose hydrate α-D-Lactose hydrate	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes .

HY-101988R

Prostaglandin D2 (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin D2 (Standard) is the analytical standard of Prostaglandin D2. This product is intended for research and analytical applications. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .

HY-N0322

Cholesterol Maximum Cited Publications 35 Publications Verification	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Cancer	Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-W592871

10-Hydroxy-2-decenoic acid 10-HDA	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	mTOR
10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans .

HY-128749AR

D-Glucaric acid (tetrahydrate) (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
D-Glucaric acid (tetrahydrate) (Standard) is the analytical standard of D-Glucaric acid (tetrahydrate). This product is intended for research and analytical applications. D-Glucaric acid tetrahydrate is the end-products of the D-glucuronic acid pathway in mammals. D-Glucaric acid tetrahydrate is also found in fruits and vegetables. D-Glucaric acid tetrahydrate can be used to reduce cholesterol and inhibits tumor development. D-Glucaric acid tetrahydrate also enhances human immunity and reduce cancer risks .

HY-W004305

Hexadecanal Palmitaldehyde	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hexadecanal (Palmitaldehyde) , a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal(OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression

HY-N0322R

Cholesterol (Standard) Maximum Cited Publications 35 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Cancer	Liposome Estrogen Receptor/ERR Endogenous Metabolite Bacterial
Cholesterol (Standard) is the analytical standard of Cholesterol. This product is intended for research and analytical applications. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-W087904R

α-Lactose (hydrate) (Standard)	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (Standard) is the analytical standard of α-Lactose (hydrate). This product is intended for research and analytical applications. α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes .

HY-N0322A

Cholesterol (Water Soluble) Maximum Cited Publications 35 Publications Verification	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Liposome
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .

Cat. No.	Product Name	Chemical Structure

HY-101988S1

Prostaglandin D2-d9
Prostaglandin D2-d₉ is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

HY-N0322S

Cholesterol-d7

Cholesterol-d₇ is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S4

Cholesterol-13C3

Cholesterol- ¹³C₃ is the ¹³C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S2

Cholesterol-d6-1

Cholesterol-d₆-1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S3

Cholesterol-13C5

Cholesterol- ¹³C₅ is the ¹³C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S5

Cholesterol-13C2

Cholesterol- ¹³C₂ is the ¹³C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S1

Cholesterol-d6

Cholesterol-d₆ is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-101988S

Prostaglandin D2-d4
Prostaglandin D2-d₄ is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].

HY-B1851S

Hexythiazox-d11
Hexythiazox-d₁₁ is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites[1][2].

HY-N0322S6

Cholesterol-d4

Cholesterol-d₄ is deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S7

Cholesterol-d1

Cholesterol-d1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322S8

Cholesterol-18O

Cholesterol- ¹⁸O is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-W004305S

Hexadecanal-d5

Hexadecanal-d₅ (Palmitaldehyde-d₅) is deuterium labeled Hexadecanal. Hexadecanal (Palmitaldehyde) , a volatile long-chain aliphatic aldehyde, is emitted from human feces, skin, and breath. The receptor for hexadecanal(OR37B) is highly conserved across mammals. Hexadecanal may exert its effects by modulating functional connectivity between the brain substrates of social appraisal and the brain substrates of aggressive execution. Also, Hexadecanal is confirmed to be highly deterrent to the ant Lasius niger. Hexadecanal is promising for the research of startle responses and aggression

Cat. No.	Product Name		Classification

HY-150734A

ODN 2007 sodium		CpG ODNs
ODN 2007 sodium, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 sodium can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .

HY-N0322

Cholesterol 30+ Cited Publications		Emulsifiers
Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .

HY-N0322A

Cholesterol (Water Soluble) 30+ Cited Publications		Cholesterol
Cholesterol Water Soluble is a major sterol in mammals, constituting 20-25% of the structural composition of the plasma membrane. The plasma membrane is highly permeable to water but relatively impermeable to ions and protons. Cholesterol Water Soluble plays an important role in determining the fluidity and permeability characteristics of membranes and the function of transporters and signaling proteins. Cholesterol Water Soluble is also an endogenous estrogen-related receptor alpha (ERRα) agonist. Cholesterol Water Soluble can be used to study the effects of cholesterol on potassium currents in inner hair cells .

HY-150734

ODN 2007		CpG ODNs
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3' .

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