2. Gene
  3. SGF29 - SAGA complex associated factor 29 Gene

SGF29 - SAGA complex associated factor 29 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as STAF36; TDRD29; CCDC101

Gene ID: 112869 | Gene type: protein coding

About SGF29

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,553,920-28,591,790 (from NCBI)

This gene has 7 transcripts (splice variants) and 199 orthologues. Ubiquitous expression in testis (RPKM 13.2), ovary (RPKM 12.9) and 25 other tissues.

Summary

CCDC101 is a subunit of 2 Histone Acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010]

SGF29 Products(1)

mRNA Protein Name
NM_138414.3 NP_612423.1 SAGA-associated factor 29
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables methylated histone binding IDA
IDA: Inferred from direct assay
20850016 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18838386 GOA
involved in regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
19936620 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
19103755 GOA
involved in regulation of cell division IDA
IDA: Inferred from direct assay
20562830 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
22055187 GOA
involved in regulation of tubulin deacetylation IMP
IMP: Inferred from mutant phenotype
20562830 GOA
involved in response to endoplasmic reticulum stress IMP
IMP: Inferred from mutant phenotype
23894581 GOA
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
23894581 GOA
Cellular Component GO Annotation Evidence Reference Source
part of ATAC complex IDA
IDA: Inferred from direct assay
18838386 GOA
part of SAGA-type complex IDA
IDA: Inferred from direct assay
18838386 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SGF29 Protein Structure

DUF1325

DUF1325: SGF29 tudor-like domain (158 - 288)

  • 0
  • 100
  • 200
  • 293 a.a.
Protein Preferred Names Protein Names

SAGA-associated factor 29

SAGA-associated factor 29 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-158009 SGF29-IN-1 Inhibitor ≥98.0% Unkown
HY-RS12796 SGF29 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SGF29 RGD RGD:1310609
Macaca mulatta SGF29 VGNC VGNC:97827
Mus musculus SGF29 MGD MGI:1922815
Bos taurus SGF29 VGNC VGNC:97311
Felis catus SGF29 VGNC VGNC:97623
Canis familiaris SGF29 VGNC VGNC:97220