2. Gene
  3. TXN2 - thioredoxin 2 Gene

TXN2 - thioredoxin 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TXN; MTRX; TRX2; MT-TRX; COXPD29

Gene ID: 25828 | Gene type: protein coding

About TXN2

Cytogenetic location: 22q12.3 Genomic coordinates (GRCh38): 22:36,467,046-36,481,640 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues, 4 paralogues and is associated with 2 phenotypes. Ubiquitous expression in adrenal (RPKM 39.7), kidney (RPKM 28.5) and 25 other tissues.

Summary

This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced Apoptosis. [provided by RefSeq, Jul 2008]

TXN2 Products(1)

mRNA Protein Name
NM_012473.4 NP_036605.2 thioredoxin, mitochondrial precursor

TXN2 Protein Structure

Thioredoxin

Thioredoxin: Thioredoxin (69 - 163)

  • 0
  • 100
  • 166 a.a.
Protein Preferred Names Protein Names

thioredoxin, mitochondrial

mitochondrial thioredoxin

Recombinant TXN2 Proteins

Cat. No. Product Name Accession Purity
HY-P71393 TXN2 Protein, Human (His) Q99757 (T60-G166) ≥95%

Related Diseases

Diseases Alias
Combined Oxidative Phosphorylation Deficiency 29

COXPD29

Combined Oxidative Phosphorylation Defect Type 29
Ocular Hypertension

Hypertension, Ocular

Intraocular Pressure Increase

Oh - [Ocular Hypertension]

Oht - [Ocular Hypertension]
Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15288 TXN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TXN2 RGD RGD:71040
Canis familiaris TXN2 VGNC VGNC:48009
Bos taurus TXN2 VGNC VGNC:36533
Felis catus TXN2 VGNC VGNC:66723
Mus musculus TXN2 MGD MGI:1929468
Others TXN2 NCBI