2. Gene
  3. VENTX - VENT homeobox Gene

VENTX - VENT homeobox Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NA88A; HPX42B; VENTX2

Gene ID: 27287 | Gene type: protein coding

About VENTX

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:133,237,855-133,241,928 (from NCBI)

This gene has 1 transcript (splice variant), 143 orthologues and 9 paralogues. Broad expression in appendix (RPKM 1.9), spleen (RPKM 1.1) and 24 other tissues.

Summary

This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008]

VENTX Products(1)

mRNA Protein Name
NM_014468.4 NP_055283.1 homeobox protein VENTX
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
21325273 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
23332764 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21325273 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VENTX Protein Structure

Homeobox

Homeobox: Homeobox domain (93 - 148)

  • 0
  • 100
  • 200
  • 258 a.a.
Protein Preferred Names Protein Names

homeobox protein VENTX

VENT homeobox homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15639 VENTX Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta VENTX VGNC VGNC:106119
Canis familiaris VENTX VGNC VGNC:48254
Rattus norvegicus VENTX RGD RGD:2320944