1. Gene
  2. NFKB1 - nuclear factor kappa B subunit 1 Gene

NFKB1 - nuclear factor kappa B subunit 1 Gene

Homo sapiens

Also known as KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta

Gene ID: 4790 | Gene type: protein coding

About NFKB1

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:102,501,359-102,617,302 (from NCBI)

This gene has 25 transcripts (splice variants), 204 orthologues, 4 paralogues and is associated with 2 phenotypes. Ubiquitous expression in bone marrow (RPKM 27.7), appendix (RPKM 20.3) and 25 other tissues.

Summary

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S Proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and Bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral Infection. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Aug 2020]

NFKB1 Products(12)

mRNA Protein Name
NM_001382626.1 NP_001369555.1 nuclear factor NF-kappa-B p105 subunit isoform 1
NM_001382625.1 NP_001369554.1 nuclear factor NF-kappa-B p105 subunit isoform 1
NM_001382627.1 NP_001369556.1 nuclear factor NF-kappa-B p105 subunit isoform 2 proprotein
XM_024454069.2 XP_024309837.1 nuclear factor NF-kappa-B p105 subunit isoform X2
NM_001382628.1 NP_001369557.1 nuclear factor NF-kappa-B p105 subunit isoform 3
NM_001319226.2 NP_001306155.1 nuclear factor NF-kappa-B p105 subunit isoform 2 proprotein
XM_047415744.1 XP_047271700.1 nuclear factor NF-kappa-B p105 subunit isoform X3
XM_024454068.1 XP_024309836.1 nuclear factor NF-kappa-B p105 subunit isoform X1
NM_001165412.2 NP_001158884.1 nuclear factor NF-kappa-B p105 subunit isoform 2 proprotein
XM_047415743.1 XP_047271699.1 nuclear factor NF-kappa-B p105 subunit isoform X3
XM_047415742.1 XP_047271698.1 nuclear factor NF-kappa-B p105 subunit isoform X1
NM_003998.4 NP_003989.2 nuclear factor NF-kappa-B p105 subunit isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
1406630 GOA
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
8413223 GOA
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
17426251 GOA
enables DNA-binding transcription factor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
26801246 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
24434510 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1406630 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
26801246 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
7959007 GOA
enables actinin binding IPI
IPI: Inferred from physical interaction
25411248 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
12482991 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
7651415 GOA
enables protein sequestering activity IDA
IDA: Inferred from direct assay
1423592 GOA
enables transcription cis-regulatory region binding IDA
IDA: Inferred from direct assay
16938301 GOA
Biological Process GO Annotation Evidence Reference Source
involved in antibacterial innate immune response IDA
IDA: Inferred from direct assay
20406817 GOA
involved in canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
23811396 GOA
involved in cellular response to angiotensin IMP
IMP: Inferred from mutant phenotype
22357537 GOA
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
12958148 GOA
involved in cellular response to interleukin-6 IMP
IMP: Inferred from mutant phenotype
22357537 GOA
acts upstream of or within cellular response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
23776175 GOA
involved in cellular response to mechanical stimulus IEP
IEP: Inferred from expression pattern
19593445 GOA
involved in cellular response to nicotine IMP
IMP: Inferred from mutant phenotype
22357537 GOA
involved in negative regulation of calcidiol 1-monooxygenase activity IDA
IDA: Inferred from direct assay
15243130 GOA
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
26687115 GOA
involved in negative regulation of inflammatory response IDA
IDA: Inferred from direct assay
16424369 GOA
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
24434150 GOA
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19881551 GOA
involved in non-canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
8413223 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
17426251 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
20018240 GOA
involved in positive regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
20018240 GOA
involved in positive regulation of hyaluronan biosynthetic process IDA
IDA: Inferred from direct assay
17324121 GOA
involved in positive regulation of miRNA metabolic process IMP
IMP: Inferred from mutant phenotype
22357537 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
1406630 GOA
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19955433 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
34721373 GOA
Cellular Component GO Annotation Evidence Reference Source
located in chromatin IDA
IDA: Inferred from direct assay
8413223 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
11819787 GOA
located in cytoplasm IGI
IGI: Inferred from genetic interaction
23729669 GOA
located in nucleus IDA
IDA: Inferred from direct assay
11819787 GOA
located in nucleus IGI
IGI: Inferred from genetic interaction
23729669 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NFKB1 Protein Structure

RHD_DNA_bind

RHD_DNA_bind: Rel homology DNA-binding domain (44 - 242)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (525 - 611)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (619 - 709)

Ank

Ank: Ankyrin repeat (718 - 749)

Death

Death: Death domain (818 - 891)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 968 a.a.
Protein Preferred Names Protein Names

nuclear factor NF-kappa-B p105 subunit

DNA-binding factor KBF1

nuclear factor NF-kappa-B p50 subunit

nuclear factor kappa-B DNA binding subunit

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

NFKB1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
NFKB1 P19838 COPB2 Homo sapiens P35606
BioID
35140242
Intra
NFKB1 P19838 COPB2 Homo sapiens P35606
Affinity Chrom
35140242
Intra
NFKB1 P19838 COPB2 Homo sapiens P35606
TAP
25609649
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
TAP
14743216
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
SPR
12832462
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
Enzymatic Footprint
12832462
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
Anti Tag CoIP
12832462
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
BioID
35140242
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
ITC
12832462
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
Affinity Chrom
35140242
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
Affinity Chrom
35140242
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
Pull Down
12832462
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
Y2H
21988832
Intra
NFKB1 P19838 MAP3K8 Homo sapiens P41279
TAP
25609649
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
TAP
14743216
Intra
NFKB1 P19838 NFKBIA Homo sapiens P25963
TAP
25609649
Intra
NFKB1 P19838 PDCD11 Homo sapiens Q14690
Y2H
14624448
Intra
NFKB1 P19838 HDAC1 Homo sapiens Q13547
Anti Bait CoIP
11931769
Intra
NFKB1 P19838 HDAC1 Homo sapiens Q13547
Pull Down
11931769
Intra
NFKB1 P19838 NFKB2 Homo sapiens Q00653
TAP
25609649
Intra
NFKB1 P19838 NFKB2 Homo sapiens Q00653
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 NFKB2 Homo sapiens Q00653
BioID
35140242
Intra
NFKB1 P19838 NFKB2 Homo sapiens Q00653
Affinity Chrom
35140242
Intra
NFKB1 P19838 NFKB2 Homo sapiens Q00653
TAP
14743216
Intra
NFKB1 P19838 RPS3 Homo sapiens P23396
Anti Bait CoIP
18045535
Intra
NFKB1 P19838 RPS3 Homo sapiens P23396
TAP
25609649
Intra
NFKB1 P19838 NFKBIB Homo sapiens Q15653
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 NFKBIB Homo sapiens Q15653
TAP
14743216
Intra
NFKB1 P19838 NFKBIB Homo sapiens Q15653
BioID
35140242
Intra
NFKB1 P19838 NFKBIB Homo sapiens Q15653
Affinity Chrom
35140242
Intra
NFKB1 P19838 RELB Homo sapiens Q01201
TAP
25609649
Intra
NFKB1 P19838 RELB Homo sapiens Q01201
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 RELB Homo sapiens Q01201
BioID
35140242
Intra
NFKB1 P19838 RELB Homo sapiens Q01201
Affinity Chrom
35140242
Intra
NFKB1 P19838 RELB Homo sapiens Q01201
TAP
14743216
Intra
NFKB1 P19838 TNIP1 Homo sapiens Q15025
Y2H
21988832
Intra
NFKB1 P19838 TNIP1 Homo sapiens Q15025
TAP
25609649
Intra
NFKB1 P19838 TNIP1 Homo sapiens Q15025
BioID
35140242
Intra
NFKB1 P19838 TNIP2 Homo sapiens Q8NFZ5
Y2H
21988832
Intra
NFKB1 P19838 TNIP2 Homo sapiens Q8NFZ5
TAP
25609649
Intra
NFKB1 P19838 TNIP2 Homo sapiens Q8NFZ5
BioID
35140242
Intra
NFKB1 P19838 TNIP2 Homo sapiens Q8NFZ5
Affinity Chrom
35140242
Intra
NFKB1 P19838 ABCC2 Homo sapiens Q92887
Y2H
21988832
Intra
NFKB1 P19838 ABCC2 Homo sapiens Q92887
Anti Tag CoIP
21988832
Intra
NFKB1 P19838 CTNNB1 Homo sapiens P35222
Pull Down
19358846
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
BioID
35140242
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
Y2H
10498867
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
Affinity Chrom
35140242
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
TAP
25609649
Intra
NFKB1 P19838 RELA Homo sapiens Q04206
Anti Bait CoIP
20547752
Intra
NFKB1 P19838 HIF1AN Homo sapiens Q9NWT6
Anti Tag CoIP
17003112
Intra
NFKB1 P19838 HIF1AN Homo sapiens Q9NWT6
TAP
25609649
Intra
NFKB1 P19838 HIF1AN Homo sapiens Q9NWT6
Anti Bait CoIP
17003112
Intra
NFKB1 P19838 CHUK Homo sapiens O15111
Anti Tag CoIP
35271311
Intra
NFKB1 P19838 CHUK Homo sapiens O15111
TAP
25609649
Intra
NFKB1 P19838 CHUK Homo sapiens O15111
Protein Kinase Assay
11297557
Intra
NFKB1 P19838 IKBKB Homo sapiens O14920
Protein Kinase Assay
11297557
Intra
NFKB1 P19838 IKBKB Homo sapiens O14920
Anti Tag CoIP
35271311
Cross
NFKB1 P19838 pap_hhv11 Human herpesvirus 1 P10226
Anti Tag CoIP
23636254
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant NFKB1 Proteins

Cat. No. Product Name Accession Purity
HY-P71124 NFKB1 Protein, Human (His) P19838-2 (M1-G434) ≥95%

Related Diseases

Diseases Alias
Burkitt Lymphoma

Burkitt'S Lymphoma

BL

Burkitt Lymphoma, Somatic

Burkitt Lymphoma/Leukaemia

Burkitt'S Tumor

Burkitt'S Tumor Or Lymphoma

Malignant Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma

Burkitt Tumor

Burkitts Lymphoma

Lymphoma, Small Noncleaved-Cell

Burkitt Tumour

Diffuse Small Noncleaved Malignant Burkitt Lymphoma

Malignant Burkitt Lymphoma

“Burkitt-Like” Lymphoma

Undifferentiated Burkitt Lymphoma

Small Noncleaved Cell Burkitt Lymphoma

Huntington Disease

Huntington'S Disease

Huntington Chorea

HD

Huntington'S Chorea

Huntington Chronic Progressive Hereditary Chorea

Juvenile Huntington Disease

Chronic Progressive Chorea

Chronic Progressive Hereditary Chorea

Hc - [Huntington Chorea]

Hereditary Chorea

Progressive Hereditary Chorea

Incontinentia Pigmenti

Bloch-Sulzberger Syndrome

IP

Incontinentia Pigmenti, Familial Male-Lethal Type

Incontinentia Pigmenti Syndrome

Bloch-Siemens Syndrome

Ip2

Incontinentia Pigmenti, Type Ii, Formerly

Ip2, Formerly

Incontinentia Pigmenti Type 2

Bloch-Siemens-Sulzberger Syndrome

Familial Incontinentia Pigmenti Male-Lethal Type

Familial Incontinentia Pigmenti Type Ii

Incontinentia Pigmenti, Type Ii

Bloch Sulzberger Syndrome

Incontinentia Pigmenti Achromians

Incontinentia Pigmenti Of Bloch-Sulzberger

Nevus Pigmentosus Systematicus

Prion Disease

Spongiform Encephalopathy

Transmissible Spongiform Encephalopathies

Prion Diseases

Prion Disease Pathway

Transmissible Spongiform Encephalopathy

Prion Induced Disorder

Prion Protein Disease

Inherited Human Transmissible Spongiform Encephalopathies

Prion Protein Diseases

Prion-Associated Disorders

Prion-Induced Disorders

Transmissible Dementias

Tses

Human Prion Disease

Tse

Encephalopathy, Transmissible Spongiform

Prion Disease, Susceptibility To

Spongiform Encephalopathies

Human Transmissible Spongiform Encephalopathies, Inherited

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Measles

Rubeola

Morbilli

Measles Nos

Koplik Spots

Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Osteopetrosis

Albers-Schonberg Disease

Marble Bone Disease

Osteopetroses

Marble Bones

Osteopetrosis And Related Disorders

Congenital Osteopetrosis

Marble Bone

Albers-Schoenberg Disease

Albers-Schonberg Osteopetrosis

Osteosclerosis Fragilis

Ivory Bones

Newcastle Disease

Newcastle'S Disease

Pseudo-Fowlpest

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Protection Against

Lung Cancer, Susceptibility To

Adenocarcinoma Of Lung, Somatic

Nonsmall Cell Lung Cancer

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Ulcerative Colitis

Colitis Gravis

Left Sided Ulcerative Colitis

Left-Sided Ulcerative Colitis

Idiopathic Proctocolitis

Inflammatory Bowel Disease, Ulcerative Colitis Type

Uc

Colitis Ulcerative

Colitis, Ulcerative

Chronic Left-Sided Ulcerative Colitis

Uc - [Ulcerative Colitis]

Chronic Ulcerative Enteritis

Mucosal Proctocolitis

Ulcerative Mucosal Proctocolitis

Left Hemicolitis

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Oligospermia
Diabetes Mellitus

Diabetes

Immunodeficiency 12

Combined Immunodeficiency Due To Malt1 Deficiency

IMD12

Immunodeficiency, Type 12

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Intestinal Perforation

Perforation Of Intestine

Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly

Alcohol Dependence

Alcoholism

Alcohol Dependence, Susceptibility To

Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against

Alcohol Dependence, Protection Against

Alcoholism, Susceptibility To

Alcoholic Intoxication, Chronic

Pharyngeal Neoplasms

Chronic Alcoholism

Dipsomania

Alcohol Addiction

Ethanol Dependence

Chronic Ethanolism

Chronic Alcoholic Disease Nos

Alcoholic Disease Nos

Alcoholic

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Common Variable Immunodeficiency

Cvid

Common Variable Agammaglobulinemia

Acquired Hypogammaglobulinemia

Common Variable Immune Deficiency

Hypogamma-Globulinemia, Acquired

Idiopathic Immunoglobulin Deficiency

Primary Antibody Deficiency

Primary Hypogammaglobulinemia

Acquired Agammaglobulinemia

Sporadic Hypogammaglobulinemia

Common Variable Hypogamma-Globulinemia

Immunoglobulin Deficiency, Late-Onset

Common Variable Hypogammaglobulinemia

Immunodeficiency, Common Variable

Pancreatic Cancer

Pancreatic Carcinoma

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Carcinoma Of Pancreas

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Cancer Of The Pancreas

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Ectodermal Dysplasia

Congenital Ectodermal Defect

Congenital Ectodermal Dysplasia

Ectodermal Dysplasia Syndrome

Dysplasia, Ectodermal

Covid-19

2019 Novel Coronavirus

2019-Ncov Infection

Covid19

Sars-Cov-2 Infection

Wuhan Coronavirus Infection

Wuhan Seafood Market Pneumonia Virus Infection

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Combined Immunodeficiency

Combined T Cell And B Cell Immunodeficiency

Congenital Combined Immunodeficiency

Syndrome With Combined Immunodeficiency

Combined T And B Cell Immunodeficiency

Combined Immunity Deficiency

Combined Immunodeficiency Syndrome

Combined T-Cell And B-Cell Immunodeficiency

Lymphopenic Agammaglobulinaemia

Immunodeficiency, Common Variable, 12, With Autoimmunity

Immunodeficiency, Common Variable, 12

CVID12

Nfkb1 Deficiency

Esophageal Tuberculosis

Tuberculosis Of Esophagus

Squamous Cell Carcinoma

Epidermoid Carcinoma

Squamous Cell Cancer

Carcinoma, Squamous Cell

Malignant Squamous Cell Tumor

Squamous Carcinoma

Squamous Cell Epithelioma

Squamous Cell Skin Cancer

Carcinoma Squamous Cell

Neoplasms, Squamous Cell

Squamous Cell Carcinoma - Category

Malignant Squamous Cell Neoplasm

Squamous Cell Carcinoma Of Skin

Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Congenital Anomaly Of Heart

Heart Defect

Heart Malformation

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure

Rabies

Lyssa

Hydrophobia

St Hubert Disease

Aging
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Colitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta NFKB1 VGNC VGNC:75339
Rattus norvegicus NFKB1 RGD RGD:70498
Bos taurus NFKB1 VGNC VGNC:32043
Canis familiaris NFKB1 VGNC VGNC:43780
Mus musculus NFKB1 MGD MGI:97312
Felis catus NFKB1 VGNC VGNC:68481
Others NFKB1 NCBI