PNP - purine nucleoside phosphorylase Gene

Homo sapiens

Also known as NP; PUNP; PRO1837

Gene ID: 4860 | Gene type: protein coding

About PNP

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,469,406-20,477,089 (from NCBI)

This gene has 11 transcripts (splice variants), 540 orthologues, 1 paralogue and is associated with 2 phenotypes. Broad expression in bone marrow (RPKM 94.2), kidney (RPKM 44.4) and 18 other tissues.

Summary

This gene encodes an Enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The Enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect Enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008]

PNP Products(1)

mRNA	Protein	Name
NM_000270.4	NP_000261.2	purine nucleoside phosphorylase

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables identical protein binding	IPI IPI: Inferred from physical interaction	20212140	GOA
enables nucleoside binding	IDA IDA: Inferred from direct assay	9305962	GOA
enables phosphate ion binding	IDA IDA: Inferred from direct assay	18938130	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA
enables purine nucleobase binding	IDA IDA: Inferred from direct assay	9305962	GOA
enables purine-nucleoside phosphorylase activity	IDA IDA: Inferred from direct assay	3029074	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in IMP catabolic process	IDA IDA: Inferred from direct assay	6771276	GOA
involved in allantoin metabolic process	IDA IDA: Inferred from direct assay	6771276	GOA
involved in dAMP catabolic process	IDA IDA: Inferred from direct assay	6771276	GOA
involved in deoxyadenosine catabolic process	IDA IDA: Inferred from direct assay	6771276	GOA
involved in deoxyinosine catabolic process	IDA IDA: Inferred from direct assay	6771276	GOA
involved in immune response	IMP IMP: Inferred from mutant phenotype	16930574	GOA
acts upstream of or within inosine catabolic process	IDA IDA: Inferred from direct assay	16964310	GOA
involved in inosine catabolic process	IDA IDA: Inferred from direct assay	23438750	GOA
involved in nicotinamide riboside catabolic process	IDA IDA: Inferred from direct assay	19001417	GOA
involved in nucleobase-containing compound metabolic process	IDA IDA: Inferred from direct assay	3029074	GOA
involved in nucleotide biosynthetic process	IGI IGI: Inferred from genetic interaction	19001417	GOA
acts upstream of or within positive regulation of T cell proliferation	IDA IDA: Inferred from direct assay	16964310	GOA
acts upstream of or within positive regulation of alpha-beta T cell differentiation	IDA IDA: Inferred from direct assay	16964310	GOA
involved in positive regulation of interleukin-2 production	IMP IMP: Inferred from mutant phenotype	16930574	GOA
involved in purine-containing compound salvage	IDA IDA: Inferred from direct assay	18938130	GOA
involved in response to xenobiotic stimulus	IMP IMP: Inferred from mutant phenotype	15047506	GOA
acts upstream of or within urate biosynthetic process	IDA IDA: Inferred from direct assay	16964310	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	3029074	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PNP Protein Structure

PNP_UDP_1

0
100
200
289 a.a.

Protein Preferred Names

Protein Names

purine nucleoside phosphorylase

HEL-S-156an

Recombinant PNP Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74665	Nucleoside phosphorylase/PNP Protein, Human (His)	P00491 (M1-S289)	≥95%

Related Diseases

Diseases

Alias

Purine Nucleoside Phosphorylase Deficiency

Purine-Nucleoside Phosphorylase Deficiency	Pnp Deficiency
Nucleoside Phosphorylase Deficiency	Immunodeficiency Due To Purine Nucleoside Phosphorylase Deficiency
Deficiency Of Inosine Phosphorylase	Pnpase Deficiency
PNPD

Adenosine Deaminase Deficiency

Ada Deficiency	Ada-Scid
Severe Combined Immunodeficiency Due To Adenosine Deaminase Deficiency	Adenosine Deaminase Deficient Severe Combined Immunodeficiency
Scid Due To Ada Deficiency	Severe Combined Immunodeficiency Due To Ada Deficiency
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Negative, Due To Adenosine Deaminase Deficiency	Ada
Scid Due To Adenosine Deaminase Deficiency

Lesch-Nyhan Syndrome

Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency	LNS
Hprt Deficiency	Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency	X-Linked Hyperuricemia
Choreoathetosis Self-Mutilation Syndrome	Hprt1 Deficiency
Hprt Deficiency, Complete	Deficiency Of Imp Pyrophosphorylase
Hgprt Deficiency	Lesch-Nyhan Disease
Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency	Hg-Prt Deficiency
Hypoxanthine-Guanine-Phosphoribosyltransferase Deficiency	Lesch - Nyhan Syndrome
Hprt1 Disorders	Lesch Nyhan Syndrome
Complete Hprt Deficiency Complete	Lesch Nyhan Disease
Complete Hprt Deficiency	Deficiency Of Guanine Phosphoribosyltransferase
Deficiency Of Hypoxanthine Phosphoribosyltransferase	Hypoxanthine Phosphoribosyltransferase Deficiency
Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome	Juvenile Hyperuricemia Syndrome
Lnd	Primary Hyperuricemia Syndrome
Total Hprt Deficiency	Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency
X-Linked Primary Hyperuricemia	X-Linked Uric Aciduria Enzyme Defect
Hprt Complete Deficiency	Hprt Deficiency Grade Iv
Hypoxanthine Guanine Phosphoribosyltransferase Complete Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade Iv
Hypoxanthine-Guanine Phosphoribosyltransferase 1 Deficiency	Hprt - [ Hypoxanthine-Guanine Phosphoribosyltransferase] Complete Deficiency
Total Hgprt - [Hypoxanthine-Guanine Phosphoribosyltransferase] Deficiency

Molybdenum Cofactor Deficiency

Combined Molybdoflavoprotein Enzyme Deficiency	Mocod
Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase, And Aldehyde Oxidase	Combined Deficiency Of Sulfite Oxidase, Xanthine Dehydrogenase And Aldehyde Oxidase
Combined Xanthine Oxidase And Sulfite Oxidase And Aldehyde Oxidase Deficiency	Deficiency Of Molybdenum Cofactor
Deficiency, Molybdenum Cofactor

Purine-Pyrimidine Metabolic Disorder

Inborn Errors Of Purine-Pyrimidine Metabolism

Disorder Of Purine Or Pyrimidine Metabolism

Severe Combined Immunodeficiency

Scid	Severe Combined Immunodeficiency Disease
Combined T And B Cell Inborn Immunodeficiency	Immunodeficiency, Severe Combined
Scid - [Severe Combined Immunodeficiencies]

Gout

Gouty Arthritis	Articular Gout
Gouty Arthropathy	Arthritis, Gouty
Arthritis Gouty	Idiopathic Gout
Idiopathic Gout, Unspecified Site	Gouty Bursitis
Uratic Arthritis	Gout Nos
Gouty	Gouty Diathesis

Combined Immunodeficiency

Combined T Cell And B Cell Immunodeficiency	Congenital Combined Immunodeficiency
Syndrome With Combined Immunodeficiency	Combined T And B Cell Immunodeficiency
Combined Immunity Deficiency	Combined Immunodeficiency Syndrome
Combined T-Cell And B-Cell Immunodeficiency	Lymphopenic Agammaglobulinaemia

Hemolytic Anemia

Anemia, Hemolytic	Anemia Hemolytic
Anaemia Due To Other Disorders Of Glutathione Metabolism	Chronic Non Spherocytic Anaemia
G6pd - [Glucose-6-Phosphate Dehydrogenase Deficiency] Anaemia	Anaemia Due To Glucose-6-Phosphate Dehydrogenase Deficiency
Glucose-6-Phosphate Dehydrogenase Deficiency With Anaemia	Glucose-6-Phosphate Dehydrogenase Deficiency Anaemia
Favism Anaemia	Haemolytic Anaemia Due Tog6pd Deficiency
Favism	Pentose Phosphate Pathway Disorder Anaemia
Anaemia Due To Pentose Phosphate Pathway Defect

Pellagra

Niacin Deficiency	Niacin-Tryptophan Deficiency
Pellagroid Syndrome

Primary Cutaneous T-Cell Non-Hodgkin Lymphoma

Cutaneous T-Cell Lymphoma	Cutaneous T Cell Lymphoma
Lymphoma, T-Cell, Cutaneous	Ctcl
Lymphoma T-Cell Cutaneous

Hyperuricemia, Hprt-Related

Hprt-Related Gout	Kelley-Seegmiller Syndrome
Hprt Deficiency, Partial	HRH
Gout, Hprt-Related	Hprt1 Deficiency, Partial
Hrpt-Related Hyperuricemia	Hprt Deficiency, Grade I
Hprt Partial Deficiency	Hprt-Related Hyperuricemia
Hprt1 Partial Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase 1 Partial Deficiency
Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade I	Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency
Partial Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency	Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency, Partial
Hyperuricemia, Hrpt-Related

Reticular Dysgenesis

Severe Combined Immunodeficiency With Leukopenia	De Vaal Disease
Congenital Aleukia	Aleukocytosis
Hematopoietic Hypoplasia, Generalized	Reticular Dysgenesia
Devaal Disease	Rd
Ak2 Deficiency	Congenital Aleukocytosis
Generalized Hematopoietic Hypoplasia	Scid With Leukopenia
RDYS

Common Variable Immunodeficiency

Cvid	Common Variable Agammaglobulinemia
Common Variable Immune Deficiency	Acquired Hypogammaglobulinemia
Hypogamma-Globulinemia, Acquired	Idiopathic Immunoglobulin Deficiency
Primary Antibody Deficiency	Primary Hypogammaglobulinemia
Acquired Agammaglobulinemia	Sporadic Hypogammaglobulinemia
Common Variable Hypogamma-Globulinemia	Immunoglobulin Deficiency, Late-Onset
Common Variable Hypogammaglobulinemia	Immunodeficiency, Common Variable

Maxillary Sinus Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Maxillofacial Sinus

Maxillary Sinus Cancer

Malignant Neoplasm Of Antrum	Malignant Tumor Of The Maxillary Sinus
Maxillary Sinus Carcinoma	Cancer Of Maxillary Sinus
Maxillary Sinus Neoplasms

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency
Primary Immunodeficiency Disease	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

Pancreatic Cancer

Pancreatic Carcinoma	Carcinoma Of Pancreas
Familial Pancreatic Carcinoma	Pancreatic Neoplasm
Pancreatic Carcinoma, Familial	Malignant Neoplasm Of Pancreas
Pancreatic Acinar Carcinoma	Pancreatic Tumor
Familial Pancreatic Cancer	Neoplasm Of The Pancreas
Cancer Of The Pancreas	Pancreatic Carcinoma, Somatic
Pancreatic Cancer, Somatic	Ca Body Of Pancreas
Ca Head Of Pancreas	Ca Tail Of Pancreas
Malignant Neoplasm Of Body Of Pancreas	Malignant Neoplasm Of Head Of Pancreas
Malignant Neoplasm Of Tail Of Pancreas	Pancreas Neoplasm
Exocrine Cancer	Exocrine Pancreas Carcinoma
Hereditary Pancreatic Cancer	Hereditary Pancreatic Carcinoma
PNCA	Pancreatic Cancer, Susceptibility To
Carcinoma Of Head Of Pancreas	Pancreatic Neoplasms
Pancreatic Tumors	Cancer, Pancreatic
Cancer Of Pancreas	Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

T Cell Deficiency

T Cell Immunodeficiency	T Lymphocyte Deficiency
T Lymphocyte Immunodeficiency	T-Lymphocyte Deficiency

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia	Acute T Cell Leukemia
Precursor T Lymphoblastic Leukemia	Precursor T-Lymphoblastic Lymphoma/Leukemia
T Acute Lymphoblastic Leukemia	T-Cell Acute Lymphocytic Leukaemia
T-Cell Lymphoblastic Leukemia/Lymphoma	Leukemia T-Cell
Leukemia, T-Cell	Leukemia, Acute, Lymphoblastic, T-Cell
Leukemia, T-Cell Acute Lymphoblastic	Leukemia, Acute T-Cell
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Precursor T-Cell Lymphoblastic Lymphoma
Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Bare Lymphocyte Syndrome, Type Ii

Mhc Class Ii Deficiency	Bare Lymphocyte Syndrome
Major Histocompatibility Complex Class Ii Deficiency	Bare Lymphocyte Syndrome 2
Bare Lymphocyte Syndrome Type 2	Severe Combined Immunodeficiency, Hla Class Ii-Negative
Bare Lymphocyte Syndrome, Type Ii, Complementation Group C	Bare Lymphocyte Syndrome, Type Ii, Complementation Group D
Bare Lymphocyte Syndrome Type Ii	Scid, Hla Class Ii-Negative
Bare Lymphocyte Syndrome, Type Ii, Complementation Group A	Bare Lymphocyte Syndrome, Type Ii, Complementation Group B
Scid Due To Absent Class Ii Hla Antigens	Hla Class 1 Deficiency
Scid, Hla Class 2-Negative	Bls Type Ii
Bare Lymphocyte Syndrome Type 2, Complementation Group A	Bare Lymphocyte Syndrome Type 2, Complementation Group E
Severe Combined Immunodeficiency	Bls, Type Ii
Bls	Bare Lymphocyte Syndrome, Type Ii, Complementation Group E
Blsii	Bls Type 1
Bls 2	Scid Due To Absence Of Class Ii Hla Antigens
Severe Combined Immunodeficiency Due To Absent Class Ii Human Leukocyte Antigens	Immunodeficiency By Defective Expression Of Mhc Class Ii
BLS2	Bare Lymphocyte Syndrome Type Ii Complementation Group A
Bare Lymphocyte Syndrome Type Ii Complementation Group B	Bare Lymphocyte Syndrome Type Ii Complementation Group C
Bare Lymphocyte Syndrome Type Ii Complementation Group D	Bare Lymphocyte Syndrome Type Ii Complementation Group E
Bls Ii	Hereditary Mhc Class Ii Deficiency
Hla Class Ii Deficient Combined Immunodeficiency	Mhc-Ii Deficiency
Scid Hla Class Ii-Negative	Severe Combined Immunodeficiency Hla Class Ii-Negative
Bl-2	Immunodeficiency By Defective Expression Of Hla Class 2
Hla Class 2-Negative Severe Combined Immunodeficiency

Hematologic Cancer

Hematologic Neoplasm	Hematologic Neoplasms
Hematologic Malignancies	Blood Cancer
Hematologic Malignancy	Hematological Tumors
Hematopoietic And Lymphoid System Tumor	Hematopoietic Cancer
Hematopoietic Neoplasm	Hematopoietic Tumors
Malignant Hematopoietic Neoplasm	Liquid Tumor
Hematopoietic Neoplasms

Omenn Syndrome

Histiocytic Medullary Reticulosis	Severe Combined Immunodeficiency With Hypereosinophilia
Combined Immunodeficiency With Hypereosinophilia	Reticuloendotheliosis, Familial, With Eosinophilia
Reticuloendotheliosis Familial With Eosinophilia	Familial Reticuloendotheliosis
Omenn'S Syndrome	OS
Malignant Histiocytosis

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia	B-Cell Chronic Lymphocytic Leukemia
CLL	B-Cell Chronic Lymphoid Leukemia
Chronic Lymphatic Leukemia	Chronic Lymphocytic Leukaemia
Lymphoplasmacytic Leukemia	Small Lymphocytic Lymphoma
Leukemia, Chronic Lymphatic	B-Cell Chronic Lymphocytic Leukaemia
Chronic Lymphatic Leukaemia	Lymphoplasmacytic Leukaemia
B Cell Chronic Lymphocytic Leukemia	Chronic B-Cell Lymphocytic Leukemia
Leukemia, Lymphocytic, Chronic	B-Cll
Chronic Lymphoid Leukemia	Leukemia Lymphocytic Chronic
Lymphoma Small Lymphocytic	Leukemia, Lymphocytic, Chronic, B-Cell

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-16209	Forodesine hydrochloride	99.86%	Yes
HY-W011727A	Pyridoxal 5'-phosphate monohydrate	≥98.0%	Unkown
HY-16210	Forodesine	99.88%	Yes

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-19480	Ulodesine		99.00%	Phase 2
HY-106934A	Peldesine dihydrochloride	Inhibitor	99.63%	Phase 1
HY-106934	Peldesine	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (74)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-20336	Mc-Val-Cit-PABC-PNP		98.89%	Unkown
HY-41189	Fmoc-Val-Cit-PAB-PNP		98.99%	Unkown
HY-136329	β-D-glucuronide-pNP-carbonate		99.44%	Unkown
HY-136136	Fmoc-Val-Ala-PAB-PNP		98.90%	Unkown
HY-W008638	2'-Deoxyinosine		99.83%	Unkown
HY-137827	4-Nitrophenyl β-D-Cellobioside		99.48%	Unkown
HY-140150	Azido-PEG3-Val-Cit-PAB-PNP		99.09%	Unkown
HY-P2724	Purine nucleoside phosphorylase, Microorganism		/	Unkown
HY-141142	Boc-Val-Cit-PAB-PNP		98.96%	Unkown
HY-148425	Mal-amide-PEG8-Val-Ala-PAB-PNP		99.60%	Unkown
HY-W039442	2′-Deoxy-2′-fluoroadenosine		≥99.0%	Unkown
HY-128933	AMP-PNP tetralithium	Inhibitor	≥97.0%	Unkown
HY-130937	DBCO-Val-Cit-PABC-PNP		96.54%	Unkown
HY-139362	Enpp-1-IN-2	Inhibitor	99.16%	Unkown
HY-112835	Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside		99.42%	Unkown
HY-136154	Fmoc-Glu-(Boc)-Val-Cit-PAB-PNP		96.67%	Unkown
HY-135975	MC-Val-Ala-PAB-PNP		99.51%	Unkown
HY-W039911	4-Nitrophenyl α-D-galactopyranoside		98.53%	Unkown
HY-140147	Mal-amido-PEG2-Val-Cit-PAB-PNP		98.40%	Unkown
HY-114430	Fmoc-Phe-Lys(Boc)-PAB-PNP		98.67%	Unkown
HY-140145	Mal-PEG4-Val-Cit-PAB-PNP		98.05%	Unkown
HY-148461	Mal-VC-PAB-PNP		96.86%	Unkown
HY-130932	Boc-Val-Ala-PAB-PNP		≥98.0%	Unkown
HY-121106	9-Deazaguanine		99.18%	Unkown
HY-147164	MC-Gly-Gly-Phe-Gly-PAB-PNP		/	Unkown
HY-129352	Cbz-Phe-(Alloc)Lys-PAB-PNP		/	Unkown
HY-131156	Mal-PEG2-Val-Cit-PABA-PNP		96.82%	Unkown
HY-118047	CI 972 anhydrous	Inhibitor	/	Unkown
HY-129350	Fmoc-Phe-Lys(Trt)-PAB-PNP		/	Unkown
HY-129351	Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP		/	Unkown
HY-129353	Boc-Phe-(Alloc)Lys-PAB-PNP		/	Unkown
HY-129361	Fmoc-Ala-Ala-Asn-PABC-PNP		/	Unkown
HY-130777	AMP-PNP		/	Unkown
HY-134354	pNP-ADPr		/	Unkown
HY-134354A	pNP-ADPr disodium		99.93%	Unkown
HY-136100	TCO-PEG1-Val-Cit-PABC-PNP		/	Unkown
HY-136105	Azido-PEG1-Val-Cit-PABC-PNP		/	Unkown
HY-136108	Fmoc-Gly3-Val-Cit-PAB-PNP		/	Unkown
HY-139247	pNPS-DHA		/	Unkown
HY-139856	Mal-Ala-Ala-PAB-PNP		/	Unkown
HY-140144	Mal-PEG1-Val-Cit-PAB-PNP		98.41%	Unkown
HY-141145	OPSS-Val-Cit-PAB-PNP		/	Unkown
HY-144628	Fmoc-Asn-Pro-Val-PABC-PNP		/	Unkown
HY-147021	MC-Val-D-Cit-PAB-PNP		/	Unkown
HY-147021A	MC-D-Val-Cit-PAB-PNP		/	Unkown
HY-148031	MC-Ala-Ala-Asn-PAB-PNP		/	Unkown
HY-148399	Mal-VC-PAB-PNP-CDN-A		/	Unkown
HY-158199	BCN-HS-PEG2-bis(PNP)		/	Unkown
HY-20336G	Mc-Val-Cit-PABC-PNP (GMP)		/	Unkown
HY-P2724A	Purine nucleoside phosphorylase, Bacillus sp.		/	Unkown
HY-RS10789	PNP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W145529	GalNAcβ(1-3)Galα(1-4)Galβ(1-4)Glc-β-pNP		/	Unkown
HY-W145534	GlcNAcβ(1-3)GalNAc-α-pNP		/	Unkown
HY-W145540	Galβ(1-3)[Neu5Acα(2-6)]GalNAc-α-pNP		/	Unkown
HY-W145553	GalNAcβ(1-3)GlcNAc-β-pNP		/	Unkown
HY-W145556	Galβ(1-3)GlcNAcβ(1-3)Galβ(1-4)Glc-β-pNP		/	Unkown
HY-W145607	Galβ(1-3)GalNAc-β-pNP		/	Unkown
HY-W145622	Galβ(1-3)[Neu5Acα(2-6)]GlcNAc-β-pNP		/	Unkown
HY-W145631	GalNAcβ(1-4)GlcNAc-β-pNP		/	Unkown
HY-W357155	Gal1-β-3GlcNAc-β-PNP		/	Unkown
HY-W698379	Gal1-b-4GlcNAc-α-PNP		/	Unkown
HY-W698411	GlcNAc1-β-6GalNAc-α-PNP		/	Unkown
HY-W699180	Fuc1-α-2Gal1-β-3GlcNAc-β-PNP		/	Unkown
HY-137828	4-Nitrophenyl N,N′-diacetyl-β-D-chitobioside		/	Unkown
HY-141153	Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP		/	Unkown
HY-151699	6-Azidohexanoyl-Val-Cit-PAB-PNP		/	Unkown
HY-151726	Azido-PEG(4)-Val-Cit-PAB-PNP		/	Unkown
HY-151740	4-Pentynoyl-Val-Ala-PAB-PNP		/	Unkown
HY-160703	DMBA-SIL-PNP		/	Unkown
HY-160790	β-Glu-PNP		/	Unkown
HY-20560	(Ac)Phe-Lys(Alloc)-PABC-PNP		/	Unkown
HY-W015996	4-Nitrophenyl-N-acetyl-α-D-galactosaminide		/	Unkown
HY-W591286	Alkyne-Val-Cit-PAB-PNP		/	Unkown
HY-W591336	Alloc-Val-Ala-PAB-PNP		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PNP	RGD	RGD:1597189
Canis familiaris	PNP	VGNC	VGNC:44751
Felis catus	PNP	VGNC	VGNC:80883
Macaca fascicularis	PNP	NCBI	NCBI:102146459
Mus musculus	PNP	NCBI	NCBI:18950
Others	PNP	NCBI

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