2. Gene
  3. IKZF3 - IKAROS family zinc finger 3 Gene

IKZF3 - IKAROS family zinc finger 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as AIO; IMD84; AIOLOS; ZNFN1A3

Gene ID: 22806 | Gene type: protein coding

About IKZF3

Cytogenetic location: 17q12-q21.1 Genomic coordinates (GRCh38): 17:39,757,715-39,864,312 (from NCBI)

This gene has 17 transcripts (splice variants), 133 orthologues, 11 paralogues and is associated with 71 phenotypes. Biased expression in lymph node (RPKM 17.4), spleen (RPKM 11.5) and 10 other tissues.

Summary

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

IKZF3 Products(16)

mRNA Protein Name
NM_001257408.2 NP_001244337.1 zinc finger protein Aiolos isoform 7
NM_001257409.2 NP_001244338.1 zinc finger protein Aiolos isoform 8
NM_001257410.2 NP_001244339.1 zinc finger protein Aiolos isoform 9
NM_001257411.2 NP_001244340.1 zinc finger protein Aiolos isoform 10
NM_001257412.2 NP_001244341.1 zinc finger protein Aiolos isoform 11
NM_001257413.2 NP_001244342.1 zinc finger protein Aiolos isoform 12
NM_001257414.2 NP_001244343.1 zinc finger protein Aiolos isoform 13
NM_001284514.2 NP_001271443.1 zinc finger protein Aiolos isoform 14
NM_001284515.2 NP_001271444.1 zinc finger protein Aiolos isoform 14
NM_001284516.1 NP_001271445.1 zinc finger protein Aiolos isoform 14
NM_012481.5 NP_036613.2 zinc finger protein Aiolos isoform 1
NM_183228.3 NP_899051.1 zinc finger protein Aiolos isoform 2
NM_183229.3 NP_899052.1 zinc finger protein Aiolos isoform 3
NM_183230.3 NP_899053.1 zinc finger protein Aiolos isoform 4
NM_183231.3 NP_899054.1 zinc finger protein Aiolos isoform 5
NM_183232.3 NP_899055.1 zinc finger protein Aiolos isoform 6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
34155405 GOA
enables histone deacetylase binding IPI
IPI: Inferred from physical interaction
17646674 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
17646674 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10369681 GOA
enables protein heterodimerization activity IDA
IDA: Inferred from direct assay
34155405 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
17646674 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
34155405 GOA
Biological Process GO Annotation Evidence Reference Source
involved in regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
10369681 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10369681 GOA
located in nucleus IDA
IDA: Inferred from direct assay
10369681 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IKZF3 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (133 - 156)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (160 - 182)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (189 - 212)

  • 0
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  • 400
  • 509 a.a.
Protein Preferred Names Protein Names

zinc finger protein Aiolos

zinc finger DNA binding protein Aiolos

IKZF3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra IKZF3 Q9UKT9 FBF1 Homo sapiens Q8TES7-6
Y2H Array
25416956
Intra IKZF3 Q9UKT9 FBF1 Homo sapiens Q8TES7-6
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 POLM Homo sapiens Q6PIY2
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 POLM Homo sapiens Q6PIY2
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Y2H Array
31515488
Intra IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 LGALS14 Homo sapiens Q8TCE9
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 OAZ3 Homo sapiens Q9UMX2
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Validated Y2H
27107012
Intra IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Y2H Array
31515488
Intra IKZF3 Q9UKT9 PPP1R16B Homo sapiens Q96T49
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 CABP5 Homo sapiens Q9NP86
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Array
25416956
Intra IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Array
31515488
Intra IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 BCAS2 Homo sapiens O75934
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 PCID2 Homo sapiens Q5JVF3
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 PCID2 Homo sapiens Q5JVF3
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Validated Y2H
27107012
Intra IKZF3 Q9UKT9 PRKAB2 Homo sapiens O43741
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Y2H Array
25416956
Intra IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Validated Y2H
27107012
Intra IKZF3 Q9UKT9 POLR1C Homo sapiens O15160
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Y2H Array
31515488
Intra IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 RAD51D Homo sapiens O75771
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 GOLGA6A Homo sapiens Q9NYA3
Y2H Array
32296183
Intra IKZF3 Q9UKT9 GOLGA6A Homo sapiens Q9NYA3
Y2H Prey Pooling
32296183
Intra IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H Array
25416956
Intra IKZF3 Q9UKT9 ATPAF2 Homo sapiens Q8N5M1
Y2H
21516116
Intra IKZF3 Q9UKT9 PRKAA1 Homo sapiens Q13131
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PRKAA1 Homo sapiens Q13131
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2-2
Validated Y2H
32296183
Intra IKZF3 Q9UKT9 IKZF4 Homo sapiens Q9H2S9
Anti Tag CoIP
33961781
Intra IKZF3 Q9UKT9 CHCHD2 Homo sapiens Q9Y6H1
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 CHCHD2 Homo sapiens Q9Y6H1
Y2H Array
25416956
Intra IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 FANCL Homo sapiens Q9NW38
Y2H Array
25416956
Intra IKZF3 Q9UKT9 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra IKZF3 Q9UKT9 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra IKZF3 Q9UKT9 ZMYM2 Homo sapiens Q9UBW7
Y2H Prey Pooling
32296183
Intra IKZF3 Q9UKT9 ZMYM2 Homo sapiens Q9UBW7
Y2H Array
32296183
Intra IKZF3 Q9UKT9 CDK4 Homo sapiens P11802
Y2H Prey Pooling
32296183
Intra IKZF3 Q9UKT9 CDK4 Homo sapiens P11802
Y2H Array
32296183
Intra IKZF3 Q9UKT9 ZGPAT Homo sapiens Q8N5A5
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 PIK3R2 Homo sapiens O00459
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 PIK3R2 Homo sapiens O00459
Y2H Array
25416956
Intra IKZF3 Q9UKT9 ABLIM3 Homo sapiens O94929
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Array
32296183
Intra IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 PFDN5 Homo sapiens Q99471
Y2H Prey Pooling
32296183
Intra IKZF3 Q9UKT9 EMC2 Homo sapiens Q15006
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 EMC2 Homo sapiens Q15006
Y2H Array
25416956
Intra IKZF3 Q9UKT9 EXOSC5 Homo sapiens Q9NQT4
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 EXOSC5 Homo sapiens Q9NQT4
Y2H Array
25416956
Intra IKZF3 Q9UKT9 CDKN1A Homo sapiens P38936
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 CDKN1A Homo sapiens P38936
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 TSSK3 Homo sapiens Q96PN8
Y2H Array
25416956
Intra IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Y2H Array
25416956
Intra IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 KAT5 Homo sapiens Q92993
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 GRB2 Homo sapiens P62993
Validated Y2H
27107012
Intra IKZF3 Q9UKT9 RHOA Homo sapiens P61586
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 ING5 Homo sapiens Q8WYH8
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 ING5 Homo sapiens Q8WYH8
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
25416956
Intra IKZF3 Q9UKT9 PIN1 Homo sapiens Q13526
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TLE5 Homo sapiens Q08117
Y2H Array
25416956
Intra IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra IKZF3 Q9UKT9 NEK6 Homo sapiens Q9HC98
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 NEK6 Homo sapiens Q9HC98
Y2H Array
29892012
Intra IKZF3 Q9UKT9 EXOC8 Homo sapiens Q8IYI6
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 EXOC8 Homo sapiens Q8IYI6
Y2H Array
25416956
Intra IKZF3 Q9UKT9 KRT19 Homo sapiens P08727
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
Intra IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
27107012
Intra IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 ARMC7 Homo sapiens Q9H6L4
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Array
31515488
Intra IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 EFHC1 Homo sapiens Q5JVL4
Y2H Array
25416956
Intra IKZF3 Q9UKT9 RCOR3 Homo sapiens Q9P2K3
Y2H
21516116
Intra IKZF3 Q9UKT9 TRAPPC6A Homo sapiens O75865
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TRAPPC6A Homo sapiens O75865
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 GEM Homo sapiens P55040
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 GEM Homo sapiens P55040
Y2H Array
25416956
Intra IKZF3 Q9UKT9 NME7 Homo sapiens Q9Y5B8
Validated Y2H
32296183
Intra IKZF3 Q9UKT9 STAMBPL1 Homo sapiens Q96FJ0
Y2H Array
25416956
Intra IKZF3 Q9UKT9 AQP1 Homo sapiens P29972
Y2H Array
25416956
Intra IKZF3 Q9UKT9 AQP1 Homo sapiens P29972
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H Array
25416956
Intra IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H
21516116
Intra IKZF3 Q9UKT9 CDKN2D Homo sapiens P55273
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 MAGOHB Homo sapiens Q96A72
Y2H
21516116
Intra IKZF3 Q9UKT9 MAGOHB Homo sapiens Q96A72
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 STK16 Homo sapiens O75716
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2
Y2H
21516116
Intra IKZF3 Q9UKT9 TCAF1 Homo sapiens Q9Y4C2
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Y2H
21516116
Intra IKZF3 Q9UKT9 TEKT4 Homo sapiens Q8WW24
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 AIRIM Homo sapiens Q9NX04
Y2H Array
25416956
Intra IKZF3 Q9UKT9 NATD1 Homo sapiens Q8N6N6
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
25416956
Intra IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
29892012
Intra IKZF3 Q9UKT9 TBC1D22B Homo sapiens Q9NU19
Y2H Array
31515488
Intra IKZF3 Q9UKT9 TSTD2 Homo sapiens Q5T7W7
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 TSTD2 Homo sapiens Q5T7W7
Y2H Array
25416956
Intra IKZF3 Q9UKT9 OSGIN1 Homo sapiens Q9UJX0
Y2H Array
31515488
Intra IKZF3 Q9UKT9 OSGIN1 Homo sapiens Q9UJX0
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 AKAP9 Homo sapiens Q99996-2
Y2H Array
25416956
Intra IKZF3 Q9UKT9 AKAP9 Homo sapiens Q99996-2
Validated Y2H
25416956
Intra IKZF3 Q9UKT9 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
25416956
Intra IKZF3 Q9UKT9 MORN3 Homo sapiens Q6PF18
Y2H Array
25416956
Intra IKZF3 Q9UKT9 FOXP3 Homo sapiens Q9BZS1
Anti Tag CoIP
20676092
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Immunodeficiency 84

IMD84
Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos
Gestational Ovarian Choriocarcinoma
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Autosomal Recessive Intellectual Developmental Disorder

Mental Retardation, Autosomal Recessive

Autosomal Recessive Mental Retardation

Autosomal Recessive Non-Syndromic Mental Retardation

Autosomal Recessive Non-Syndromic Intellectual Disability
Leukemia, Acute Lymphoblastic

Acute Lymphoblastic Leukemia

ALL

Acute Lymphocytic Leukemia

Leukemia, Acute Lymphocytic, Susceptibility To, 1

Acute Lymphoblastic Leukaemia

Precursor Lymphoblastic Lymphoma/Leukemia

Precursor Lymphoid Neoplasm

Leukemia, Acute Lymphoblastic, Susceptibility To

B-Cell Acute Lymphoblastic Leukemia

Leukemia, Acute Lymphocytic 1

Acute Lymphocytic Leukaemia

Acute Lymphoblastic Leukemia/Lymphoma

All1

Childhood Acute Lymphoblastic Leukemia

Leukemia Acute Lymphoblastic 1

Leukemia Acute Lymphoblastic B-Hyperdiploid

Leukemia Acute Lymphocytic

Leukemia Acute Lymphocytic 1

Leukemia B-Cell Acute Lymphoblastic

Leukemia T-Cell Acute Lymphoblastic

Leukemia, Acute Lymphoblastic, 3

ALL3

Lymphoblastic Leukemia Acute

Leukemia, Acute, Lymphoblastic

Precursor Cell Lymphoblastic Leukemia Lymphoma

Leukemia, Lymphocytic, Acute, L1

Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-161101 MG degrader 1 99.83% Unkown
HY-168614 MGD-4 Degrader / Unkown
HY-169077 IKZF3 degrader 1 Degrader / Unkown
HY-168615 MGD-28 Degrader / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus IKZF3 RGD RGD:1307024
Felis catus IKZF3 VGNC VGNC:62900
Canis familiaris IKZF3 VGNC VGNC:41925
Mus musculus IKZF3 MGD MGI:1342542
Macaca mulatta IKZF3 VGNC VGNC:73587
Bos taurus IKZF3 VGNC VGNC:30104