2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. Indotecan hydrochloride

Indotecan hydrochloride  (Synonyms: LMP-400 hydrochloride; NSC-724998 hydrochloride)

Cat. No.: HY-18351A
Data Sheet Handling Instructions Technical Support

Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis.

For research use only. We do not sell to patients.

Indotecan hydrochloride Chemical Structure

Indotecan hydrochloride Chemical Structure

CAS No. : 1228035-68-4

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Other Forms of Indotecan hydrochloride:

Indotecan hydrochloride Related Antibodies

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Description

Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan hydrochloride prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis[1][2].

Molecular Weight

514.95

Formula

C26H27ClN2O7
CAS No.
SMILES

O=C1C2=C(C3=C1C4=CC(OC)=C(C=C4C(N3CCCN5CCOCC5)=O)OC)C=C6OCOC6=C2.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Indotecan hydrochloride Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

Indotecan1228035-68-4LMP-400NSC-724998LMP400LMP 400NSC724998NSC 724998TopoisomeraseP388HCT116MCF-7upercoiled DNAvisceral leishmaniasisInhibitorinhibitorinhibit

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