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Egf

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Compare Product Name Species Source
  • HY-P71171A
    NRG1-beta 1 Protein, Human (CHO)

    Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; Egf; NRG1; GGF; HGL; HRGA; NDF; SMDF; Heregulin β-1; Heregulin; HRG

    		 Human CHO
    NRG1-alpha protein acts as a direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concurrently recruiting ERBB1 and ERBB2 coreceptors, thereby inducing ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The diverse functions of its multiple isoforms encompass the induction of growth and differentiation in various cell types, including epithelial, glial, neuronal, and skeletal muscle cells. NRG1-alpha is also involved in the expression of acetylcholine receptors during neuromuscular junction formation, the stimulation of lobuloalveolar budding and milk production in the mammary gland, and the induction of differentiation in mammary tumor cells. Furthermore, it stimulates Schwann cell proliferation and plays a role in myocardial development, specifically contributing to the trabeculation of the developing heart. Isoform 10 is implicated in motor and sensory neuron development. NRG1-alpha binds to ERBB4 and ERBB3, acting as a ligand for integrins and forming a ternary complex with integrins and ERBB3, a crucial step in NRG1-ERBB signaling. It induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2, and AKT1. Additionally, NRG1-alpha participates in ligand-dependent ERBB4 endocytosis, essential for the activation of these kinases in neurons, and interacts with the LIM domain region of LIMK1. It also forms a ternary complex with ERBB3 and integrins ITGAV:ITGB3 or ITGA6:ITGB4 and interacts with NRDC and BACE1. NRG1-beta 1 Protein, Human (CHO) is the recombinant human-derived NRG1-beta 1 protein, expressed by CHO , with tag free. The total length of NRG1-beta 1 Protein, Human (CHO) is 71 a.a., with molecular weight of 7.5 kDa.
  • HY-P70524
    NRG1-beta 1 Protein, Human (245a.a)

    Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1; Egf; NRG1; GGF; HGL; HRGA; NDF; SMDF;

    		Human E. coli
    NRG1-α protein binds directly to ERBB3 and ERBB4 receptors, leading to the recruitment of ERBB1 and ERBB2 coreceptors. NRG1-beta 1 Protein, Human (245a.a) is the recombinant human-derived NRG1-beta 1 protein, expressed by E. coli , with tag free. The total length of NRG1-beta 1 Protein, Human (245a.a) is 245 a.a., with molecular weight of ~32-34.0 kDa.
  • HY-P7109G
    GMP EGF Protein, Human
    1 Publications Verification

    Pro-epidermal growth factor; Egf; Urogastrone

    		 Human E. coli
    EGF proteins act as potent stimulators of growth in a variety of epidermal and epithelial tissues in both in vivo and in vitro settings, while promoting the proliferation of specific fibroblasts in cell culture. This multifaceted protein also acts as a magnesium stimulating hormone, driving magnesium reabsorption in the renal distal tubule through engagement of EGFR and activation of the magnesium channel TRPM6. GMP EGF Protein, Human is the recombinant human-derived EGF protein, expressed by E. coli , with tag free. The total length of GMP EGF Protein, Human is 53 a.a., with molecular weight of ~9.6 kDa.
  • HY-P7109
    EGF Protein, Human
    Maximum Cited Publications
    40 Publications Verification

    rHuEgf; Pro-epidermal growth factor; Urogastrone

    		 Human E. coli
    EGF Protein is a potent epidermal growth factor that belongs to EGF-family of proteins. EGF Protein stimulates cell growth and differentiation by binding to epidermal growth factor receptor (EGFR) found in many human tissues, including platelets, submandibular gland (submaxillary gland) and parotid gland. EGF Protein has effects such as wound healing, anti-intestinal atrophy, anti-cancer, reducing ureteral obstruction and assisting in nerve tissue regeneration, mainly used in wound healing applications. EGF Protein (Human) is a recombinant protein with tag free that consists of 53 amino acids with three intramolecular disulfide bonds and is produced in E. coli[1],[2],[3],[4],[5],[6],[7].
  • HY-P72982
    EGF Protein, Human (Solution, HEK293, N-hFc)

    Pro-epidermal growth factor; Urogastrone; Egf; HOMG4

    		 Human HEK293
    The Progranulin/PGRN protein is involved in a variety of cellular processes, including cell growth, inflammation, and neurodegeneration. It acts as a regulator of tissue repair and has been implicated in the pathogenesis of several diseases, including Alzheimer's disease and frontotemporal dementia. Progranulin/PGRN interacts with various receptors and signaling pathways to exert its effects on cellular function and disease progression. EGF Protein, Human (Solution, HEK293, N-hFc) is the recombinant human-derived EGF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of EGF Protein, Human (Solution, HEK293, N-hFc) is 53 a.a., with molecular weight of ~37 kDa.
  • HY-P72982A
    EGF Protein, Human (HEK293, N-hFc)

    Pro-epidermal growth factor; Urogastrone; Egf; HOMG4

    		 Human HEK293
    The Progranulin/PGRN protein is involved in a variety of cellular processes, including cell growth, inflammation, and neurodegeneration. It acts as a regulator of tissue repair and has been implicated in the pathogenesis of several diseases, including Alzheimer's disease and frontotemporal dementia. Progranulin/PGRN interacts with various receptors and signaling pathways to exert its effects on cellular function and disease progression. EGF Protein, Human (HEK293, N-hFc) is the recombinant human-derived EGF protein, expressed by HEK293 , with N-hFc labeled tag.
  • HY-P70878A
    EDIL3 Protein, Human (HEK293, His)

    Egf-Like Repeats and Discoidin I-Like Domains 3; EDIL3

    		 Human HEK293
    EDIL3 Protein enhances endothelial cell adhesion by interacting with the alpha-v/beta-3 integrin receptor, while also inhibiting the formation of vascular-like structures. Its role suggests involvement in the regulation of vascular morphogenesis during embryonic development. EDIL3 Protein, Human (HEK293, His) is the recombinant human-derived EDIL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EDIL3 Protein, Human (HEK293, His) is 457 a.a., with molecular weight of ~56 kDa.
  • HY-P70878
    EDIL3 Protein, Human (HEK293, His, solution)

    Egf-Like Repeats and Discoidin I-Like Domains 3; EDIL3

    		Human HEK293
    EDIL3 Protein enhances endothelial cell adhesion by interacting with the alpha-v/beta-3 integrin receptor, while also inhibiting the formation of vascular-like structures. Its role suggests involvement in the regulation of vascular morphogenesis during embryonic development. EDIL3 Protein, Human (HEK293, His, solution) is the recombinant human-derived EDIL3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EDIL3 Protein, Human (HEK293, His, solution) is 457 a.a., with molecular weight of ~56 kDa.
  • HY-P7017
    HB-EGF Protein, Human

    rHuHB-Egf; HBEgf; Diphtheria toxin receptor; DTR

    		 Human E. coli
    HB-EGF Protein, Human is a member of the epidermal growth factor (EGF) family of growth factors that stimulate growth and differentiation.
  • HY-P72487
    HB-EGF Protein, Human (HEK293, His)

    Proheparin-binding Egf-like growth factor; HB-Egf; DT-R; DTS; HEgfL

    		 Human HEK293
    HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (HEK293, His) is the recombinant human-derived HB-EGF protein, expressed by HEK293 , with C-6*His labeled tag. The total length of HB-EGF Protein, Human (HEK293, His) is 129 a.a., with molecular weight of ~18 kDa.
  • HY-P7400
    HB-EGF Protein, Human (CHO)
    2 Publications Verification

    rHuProheparin-binding Egf-like Growth Factor; DTR; DTS; HEgfL

    		 Human CHO
    HB-EGF Protein, Human (CHO) is shown to play a role in wound healing, cardiac hypertrophy, and heart development and function.
  • HY-P73093
    HB-EGF Protein, Human (sf9)

    Proheparin-binding Egf-like Growth Factor; DTR; DTS; HEgfL; HBEgf

    		 Human Sf9 insect cells
    HB-EGF protein is a multifunctional growth factor that is regulated through EGFR, ERBB2 and ERBB4 and is critical for cardiac valve formation and cardiac function. It promotes smooth muscle cell proliferation and may contribute to macrophage-mediated cell proliferation. HB-EGF Protein, Human (sf9) is the recombinant human-derived HB-EGF protein, expressed by Sf9 insect cells , with tag free. The total length of HB-EGF Protein, Human (sf9) is 86 a.a., with molecular weight of ~16.4 kDa.
  • HY-P700051AF
    Animal-Free EGF Protein, Human (His)

    Urogastrone; URG

    		 Human E. coli
    EGF protein does not possess the conserved residue(s) necessary for propagating feature annotation. Animal-Free EGF Protein, Human (His) is the recombinant human-derived animal-FreeEGF protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free EGF Protein, Human (His) is 53 a.a., with molecular weight of ~7.16 kDa.
  • HY-P79135
    Stabilin-2 Protein, Human (His)

    Stabilin-2; STAB2; FAS1 Egf-like and X-link domain-containing adhesion molecule 2; Fasciclin, Egf-like, laminin-type Egf-like and link domain-containing scavenger receptor 2; FEEL-2; Hyaluronan receptor for endocytosis; FEEL2; FELL; FEX2; HARE

    		Human E. coli
    Stabilin-2 protein is a multifunctional phosphatidylserine and hyaluronic acid receptor that engulfs apoptotic cells and mediates hyaluronic acid endocytosis. As a systemic scavenger receptor, it binds various ligands and supports extracellular matrix turnover and body mobility. Stabilin-2 Protein, Human (His) is the recombinant human-derived Stabilin-2 protein, expressed by E. coli , with C-His labeled tag.
  • HY-P77833
    CSPG5 Protein, Human (HEK293, His)

    Chondroitin sulfate proteoglycan 5; Acidic leucine-rich Egf-like domain-containing brain protein; Neuroglycan C; CALEB; chondroitin sulfate proteoglycan 5 (neuroglycan C; MGC44034; Neuroglycan C; NGC; NGCAcidic leucine-rich Egf-like domain-containing brai

    		 Human HEK293
    The CSPG5 protein is a potential growth and differentiation factor that is actively involved in and critical for neural development. It may induce ERBB3 activation, a key pathway for cell growth and differentiation. CSPG5 Protein, Human (HEK293, His) is the recombinant human-derived CSPG5 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P76285
    CRELD1 Protein, Human (HEK293, His)

    Protein disulfide isomerase CRELD1; Cysteine-rich with Egf-like domain protein 1; CIRRIN

    		 Human HEK293
    CRELD1 Protein, acting as a protein disulfide isomerase, aids in the correct folding and assembly of proteins, crucial for cellular homeostasis. It also contributes to the proper localization of acetylcholine receptors (AChRs) to the plasma membrane, emphasizing its significance in maintaining protein structure and membrane receptor distribution. CRELD1 Protein, Human (HEK293, His) is the recombinant human-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P70081
    CRELD2 Protein, Human (HEK293, His)

    rHuProtein disulfide isomerase CRELD2/CRELD2, His; Cysteine-Rich With Egf-Like Domain Protein 2; CRELD2

    		Human HEK293
    CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Human (HEK293, His) is the recombinant human-derived CRELD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRELD2 Protein, Human (HEK293, His) is 297 a.a., with molecular weight of ~41 kDa.
  • HY-P76684
    TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc)

    TR-1; H7365; Transmembrane protein with Egf-like and one follistatin-like domain; C9orf2

    		 Human HEK293
    TMEFF1/Tomoregulin-1 protein may inhibit NODAL and BMP signaling in neural patterning, suggesting a regulatory role in neural development. It has been proposed as a tumor suppressor in brain cancer, emphasizing its importance in mitigating abnormal cell growth. TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc) is the recombinant human-derived TMEFF1/Tomoregulin-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TMEFF1/Tomoregulin-1 Protein, Human (HEK293, Fc) is 291 a.a., with molecular weight of ~65 kDa.
  • HY-P70967
    NRG1-beta 1 Protein, Human (246a.a, His)

    Pro-neuregulin-1; Neuregulin-1 beta 1; NRG1-beta 1; HRG1-beta 1 ECD; NRG1; GGF; HGL; HRGA; NDF; SMDF;

    		Human E. coli
    NRG1 is a direct ligand of the ERBB3 and ERBB4 tyrosine kinase receptors. NRG1 can induce the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2 and AKT1. NRG1 can induce cell growth, differentiation and proliferation. NRG1-beta 1 Protein, Human (246a.a, His) is the recombinant human-derived NRG1-beta 1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of NRG1-beta 1 Protein, Human (246a.a, His) is 246 a.a., with molecular weight of ~35.0 kDa.
  • HY-P700637
    CRELD2 Protein, Human (329aa, HEK293, His)

    rHuProtein disulfide isomerase CRELD2/CRELD2, His; Cysteine-Rich With Egf-Like Domain Protein 2; CRELD2

    		Human HEK293
    CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Human (329aa, HEK293, His) is the recombinant human-derived CRELD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRELD2 Protein, Human (329aa, HEK293, His) is 329 a.a., with molecular weight of ~41.88 kDa.
  • HY-P73304
    NRG1-beta 2 Protein, Human

    NRG-1 Egf-like domain beta 2; Beta2; Neuregulin-1 beta 2

    		 Human E. coli
    NRG1-α protein binds directly to ERBB3 and ERBB4 receptors, leading to the recruitment of ERBB1 and ERBB2 coreceptors. NRG1-beta 2 Protein, Human is the recombinant human-derived NRG1-beta 2 protein, expressed by E. coli , with tag free. The total length of NRG1-beta 2 Protein, Human is 61 a.a., with molecular weight of ~7.0 kDa.
  • HY-P700470
    TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His)

    TMEFF2; transmembrane protein with Egf like and two follistatin like domains 2; TR; HPP1; TPEF; TR-2; TENB2; CT120.2; tomoregulin-2; cancer/testis antigen family 120, member 2; hyperplastic polyposis protein 1; transmembrane protein TENB2; transmembrane protein with Egf-like and two follistatin-like domains

    		 Human HEK293
    TMEFF2/Tomoregulin-2 protein serves as a potential survival factor for hippocampal and midbrain neurons, supporting neuronal cell viability.In addition, its shed form may upregulate cancer cell proliferation by promoting ERK1/2 phosphorylation.TMEFF2/Tomoregulin-2 Protein, Human (HEK293, His) is the recombinant human-derived TMEFF2/Tomoregulin-2 protein, expressed by HEK293 , with C-10*His labeled tag.
  • HY-P71448
    ITGBL1 Protein, Human (Myc, His)

    ITGBL1; OSCP; TIED; Integrin beta-like protein 1; Osteoblast-specific cysteine-rich protein; Ten integrin Egf-like repeat domain-containing protein

    		 Human E. coli
    Integrin beta-like protein 1 (ITGBL1) is a beta integrin-related protein that is a member of the EGF-like protein family, containing integrin-like cysteine-rich repeats and may has integrin binding activity. ITGBL1 might be involved in cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. ITGBL1 Protein, Human (Myc, His) is the recombinant human-derived ITGBL1 protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of ITGBL1 Protein, Human (Myc, His) is 471 a.a., with molecular weight of ~67 kDa.
  • HY-P702705
    TIE-2 Protein, Human (Biotinylated, sf9, Avi)

    TEK; TEK tyrosine kinase, endothelial; venous malformations, multiple cutaneous and mucosal , VMCM; angiopoietin-1 receptor; CD202b; TIE 2; TIE2; VMCM1; hTIE2; p140 TEK; soluble TIE2 variant 1; soluble TIE2 variant 2; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine kinase with Ig and Egf homology domains-2; VMCM; TIE-2; CD202B

    		 Human Sf9 insect cells
    TIE-2 is a tyrosine protein kinase that serves as a cell surface receptor for ANGPT1, ANGPT2, and ANGPT4 and exerts a global control over angiogenesis and vascular stability. It regulates endothelial cell survival, proliferation, migration, adhesion, and actin cytoskeletal reorganization. TIE-2 Protein, Human (Biotinylated, sf9, Avi) is the recombinant human-derived TIE-2, expressed by Sf9 insect cells , with Avi labeled tag. ,

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