Search Result

Results for "

4α

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (2) Antibiotic (1) Apoptosis (1) DGK (1) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) Fluorescent Dye (2) GABA Receptor (1) GCGR (2) Glucosidase (4) HBV (1) Histamine Receptor (1) Histone Methyltransferase (1) HIV (1) Isotope-Labeled Compounds (9) Kinesin (3) Melanocortin Receptor (1) Microtubule/Tubulin (2) nAChR (3) Nucleoside Antimetabolite/Analog (5) Opioid Receptor (1) PI3K (2) PROTAC Linkers (1) Topoisomerase (1) TRP Channel (1)
By Research Areas:	Cancer (23) Cardiovascular Disease (4) Endocrinology (2) Infection (2) Inflammation/Immunology (3) Metabolic Disease (13) Neurological Disease (8)
Click Chemistry:	PROTAC Synthesis (1) Azide (3)
Oligonucleotides:	Nucleosides and their Analogs (5)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116291

4α-Phorbol 12,13-didecanoate 4αPDD	TRP Channel	Neurological Disease Inflammation/Immunology
4α-Phorbol 12,13-didecanoate (4αPDD) is a TRPV4 agonist with antidipsogenic effects. 4α-Phorbol 12,13-didecanoate promotes Ca ²⁺ influx .

HY-N8531

4α-Methylcholesterol	Others	Others
4α-Methylcholesterol is a Cholesterol derivative. 4α-Methylcholesterol can oxidize 3-hydroxy steroid, with the apparent K_m of 12.6 μM .

HY-N2408

4α-Phorbol Isophorbol; α-Phorbol	Others	Others
4α-Phorbol is a compound that can be isolated from croton oil .

HY-106029

4α-TPA α-TPA	Others	Cancer
4α-TPA is an inactive form of TPA, and is used as a negative control for TPA-activated events .

HY-N9175

4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide	Others	Others
4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .

HY-N3808

(4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid	Others	Others
(4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid is a compound isolated from the Tunisian Pulicaria laciniata (Coss.et Kral.) Thell. flowers .

HY-124013

NBDA 4-(α-N-L-alanine)-NBD	Fluorescent Dye	Others
NBDA (4-(α-N-L-alanine)-NBD) is a structural and functional analogue of the 2,4-dinitrophenyl group (DNP). NBDA can be used to detect and characterize antinitroaromatic antibodies, even in crude preparations, and possibly on cell surfaces .

HY-N4241

Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)-	Others	Others
Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)- (compound 5) is a endogenous ent-kaurane diterpene compound in green coffee beans, providing direct chemical indicators of low-quality coffee .

HY-137309

4-Deoxy-4α-phorbol	HIV	Others
4-Deoxy-4α-phorbol is a tetracyclic diterpene found in E. desmondi. It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters .

HY-138213

Afzelechin-(4α→8)-epiafzelechin	Others	Others
Afzelechin-(4α→8)-epiafzelechin is a Flavonoids product that can be isolated from the herbs of Cassia javanica .

HY-15536A

Cebranopadol ((1α,4α)stereoisomer) GRT6005 (1α,4α)stereoisomer	Opioid Receptor	Neurological Disease
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol. Cebranopadol is a potent agonist activity on ORL-1.

HY-108469

BI-6015 3 Publications Verification	Others	Metabolic Disease Cancer
BI-6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BI6015 represses insulin promoter activity through HNF4α antagonism. BI-6015 can be used for the research of cancer and diabetes .

HY-N1608

18-Norabieta-8,11,13-trien-4α-ol	Others	Others
18-Norabieta-8,11,13-trien-4α-ol (Compound 4) is a natural product that can be isolated from the resins of Populus euphratica .

HY-N11477

(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid	Glucosidase	Metabolic Disease
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid is a saponin that can be isolated from Rubus ellipticus var. obcordatus. (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid inhibits α-Glucosidase with an IC₅₀ of 1.68 mM .

HY-N3361

(3β,4α)-Lup-20(29)-ene-3,23-diol	Others	Cancer
(3β,4α)-Lup-20(29)-ene-3,23-diol (compound 11) is a natural lupane-type triterpenes betulinic acid with anti-tumor activity .

HY-119971

BIM5078	Others	Metabolic Disease Cancer
BIM5078 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BIM5078 represses insulin promoter activity through HNF4α antagonism. BIM5078 can be used for the research of cancer and diabetes .

HY-P3645

(Nle4)-α-MSH	Melanocortin Receptor	Others
(Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment .

HY-N2882

*Apigenin-4'-α-L-rhamnoside*	HBV	Infection
Apigenin-4'-α-L-rhamnoside is a potent inhibitor of HBV. Apigenin-4'-α-L-rhamnoside inhibits the secretory level of HBV surface antigen (HBsAg) in HepG2.2.15 cells .

HY-152764

4’-α-C-Methyluridine	Nucleoside Antimetabolite/Analog	Others
4’-α-C-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-152454

4’-α-C-Methylcytidine	Nucleoside Antimetabolite/Analog	Others
4’-α-C-Methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-141126

Azido-PEG4-alpha-D-mannose	PROTAC Linkers	Cancer
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-N1885

4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide	Others	Others
4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .

HY-N12147

*Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside*	Others	Cancer
Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside (Compound 12) is a cardiac glycoside that can be isolated from seeds of Thevetia peruvian. Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside shows cytotoxicity against SW1990 and MGC-803 cells (IC₅₀: 9.52 and 7.70 μM) .

HY-154590

*2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine*	Nucleoside Antimetabolite/Analog	Cancer
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B2193A

α-Amylase, Human Saliva 1,4-alpha-D-Glucan-glucanohydrolase, ptyalin	Others	Others
α-Amylase, Human Saliva (1,4-alpha-D-Glucan-glucanohydrolase, ptyalin) is a biological material or organic compound that can be used in life science research .

HY-154357

4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine	Nucleoside Antimetabolite/Analog	Cancer
4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154358

4’-alpha-C-Allyl-2’,3’-bis(O-t-butyldimethylsilyl) uridine	Nucleoside Antimetabolite/Analog	Cancer
4’-alpha-C-Allyl-2’,3’-bis(O-t-butyldimethylsilyl) uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-B2193C

α-Amylase, Porcine Pancreatic 1,4-alpha-D-Glucan-glucanohydrolase, amy2, PPA, PA	Others	Others
α-Amylase, Porcine Pancreatic (1,4-alpha-D-Glucan-glucanohydrolase, amy2, PPA, PA) is a biological material or organic compound that can be used in life science research .

HY-D1486

*4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene*	Fluorescent Dye	Others
4,4-Difluoro-8-(4'-iodophenyl)-1,7-bis-(1'-napthyl)-4-bora-3alpha,4alpha-diaza-s-indacene is a fluorescent dye for DNA sequencing .

HY-B1058

Benfluorex hydrochloride 5 Publications Verification JP-992 hydrochloride	Others	Cardiovascular Disease Metabolic Disease
Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

HY-B1058A

Benfluorex JP-992	Others	Cardiovascular Disease Metabolic Disease
Benfluorex (JP-992) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-Glucan glucohydrolase; Exo-1,4-α-glucosidase	Others	Metabolic Disease
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

HY-B1058R

Benfluorex hydrochloride (Standard)	Others	Cardiovascular Disease Metabolic Disease
Benfluorex (hydrochloride) (Standard) is the analytical standard of Benfluorex (hydrochloride). This product is intended for research and analytical applications. Benfluorex hydrochloride (JP-992 hydrochloride) is a hepatic nuclear factor 4 alpha (HNF4α) activator.

HY-131345

PI3Kα-IN-4	PI3K	Cancer
PI3Kα-IN-4 is a potent, selective and orally active inhibitor of PI3Kα, with an IC₅₀ of 1.8 nM. PI3Kα-IN-4 has antitumor activity .

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-P0082

Glucagon (1-29), bovine, human Maximum Cited Publications 9 Publications Verification Glucagon	GCGR	Metabolic Disease Cancer
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .

HY-P0082A

Glucagon (1-29), bovine, human hydrochloride Glucagon hydrochloride	GCGR	Metabolic Disease Cancer
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .

HY-151453

Topoisomerase IIα-IN-4	Topoisomerase Apoptosis	Cancer
Topoisomerase IIα-IN-4 (F2) is a non-intercalative ATP-competitive human DNA topoisomerase II inhibitor with an IC₅₀ value of 3.8 and 10.1 μM for TopoIIα and TopoIIβ, respectively. Topoisomerase IIα-IN-4 shows potent potency in apoptosis induction and cell cycle arrest in HepG2 cells. Topoisomerase IIα-IN-4 exhibits strong antitumor activities against human cancer cell lines, it can be used for the research of cancer .

HY-132649S

α-Cholestane-d4	Isotope-Labeled Compounds	Others
α-Cholestane-d₄ is the deuterium labeled α-Cholestane[1].

HY-Y0245S

α-Cyanopyridine-d4	Isotope-Labeled Compounds	Others
α-Cyanopyridine-d₄ is the deuterium labeled α-Cyanopyridine[1].

HY-155241

α-Amylase/α-Glucosidase-IN-4	Glucosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-118566S

5α-Androstenone-d4	Isotope-Labeled Compounds	Others
5α-Androstenone-d₄ is the deuterium labeled 5α-Androstenone[1].

HY-154758S

6-Alpha-Methyl-Cortisol-d4	Isotope-Labeled Compounds	Others
6-Alpha-Methyl-Cortisol-d₄ is deuterated labeled 6-Alpha-Methyl-Cortisol.

HY-154759S

6-Alpha-Methyl-Prednisolone-d4	Isotope-Labeled Compounds	Others
6-Alpha-Methyl-Prednisolone-d₄ is deuterated labeled 6-Alpha-Methyl-Prednisolone.

HY-131345A

(S)-PI3Kα-IN-4	PI3K	Cancer
(S)-PI3Kα-IN-4 is a potent inhibitor of PI3Kα, with an IC₅₀ of 2.3 nM. (S)-PI3Kα-IN-4 shows 38.3-, 4.25-, and 4.93-fold selectivity for PI3Kα over PI3Kβ, PI3Kδ, and PI3Kγ, respectively. (S)-PI3Kα-IN-4 can be used for the research of cancer .

HY-142127S

2-(α-D-Mannopyranosyl)-L-tryptophan-d4	Isotope-Labeled Compounds Antibiotic	Others
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan[1].

HY-149973

α-Amylase-IN-4	Others	Metabolic Disease
α-Amylase-IN-4 (Compd 10y) show maximum inhibition of amylase activity with IC₅₀ value 17.83 ± 0.14 μg/mL .

HY-146305

α-Glucosidase-IN-4	Glucosidase	Infection Cardiovascular Disease Others Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology Cancer
α-Glucosidase-IN-4 is a reversible and mixed type α-glucosidase inhibitor with an IC₅₀ of 12.98 μM, a K_I of 27.02 μM, and a K_IS of 13.65 μM, respectively .

HY-B1204S

Histamine-α,α,β,β-d4 dihydrochloride Ergamine-α,α,β,β-d₄ (dihydrochloride)	Histamine Receptor Endogenous Metabolite	Neurological Disease Endocrinology Cancer
Histamine-α,α,β,β-d₄ (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

HY-128579

DW14800	Histone Methyltransferase	Cancer
DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC₅₀ of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity .

Cat. No.	Product Name	Type

HY-E70165

Carbohydrate Sulfotransferase 5 EC:2.8.2.-; CHST5; GST4-α	Enzyme Substrates
Carbohydrate Sulfotransferase 5 (EC:2.8.2.-) can catalyze sulphate transfer to position 6 of non- GlcNAc residues and O-linked sugars of mucin-type acceptors .

Cat. No.	Product Name	Target	Research Area

HY-P0082

Glucagon (1-29), bovine, human 5+ Cited Publications Glucagon	GCGR	Metabolic Disease Cancer
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation .

HY-P3645

(Nle4)-α-MSH	Melanocortin Receptor	Others
(Nle4)-α-MSH is a synthetic analogue of α-MSH (HY-P0252), a melanocyte-stimulating hormone. (Nle4)-α-MSH reversibly darkens frog skins and also exhibits prolonged activity after heat-alkali treatment .

HY-P0082A

Glucagon (1-29), bovine, human hydrochloride Glucagon hydrochloride	GCGR	Metabolic Disease Cancer
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis . Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2408

4α-Phorbol Isophorbol; α-Phorbol	Structural Classification Natural Products Croton tiglium Linn. Source classification Euphorbiaceae Plants	Others
4α-Phorbol is a compound that can be isolated from croton oil .

HY-N9175

4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide	Structural Classification Terpenoids Sesquiterpenes Source classification Chloranthus erectus (Buchanan-Hamilton) Verdcourt Chloranthaceae Plants	Others
4α,6α-Dihydroxyeudesm-11(13)-en-12,8β-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .

HY-N4241

Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)-	other families Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Plants Disease Research Fields	Others
Kauran-18-oic acid, 16,17,19-trihydroxy-, (4α)- (compound 5) is a endogenous ent-kaurane diterpene compound in green coffee beans, providing direct chemical indicators of low-quality coffee .

HY-137309

4-Deoxy-4α-phorbol	Structural Classification Terpenoids Source classification Euphorbia cooperi N. E. Br. ex A. Berger Diterpenoids Euphorbiaceae Plants	HIV
4-Deoxy-4α-phorbol is a tetracyclic diterpene found in E. desmondi. It has been used in the semisynthesis of inhibitors of the HIV-1-induced cytopathic effect on MT-4 cells and 4α-phorbol esters .

HY-138213

Afzelechin-(4α→8)-epiafzelechin	Structural Classification Flavonoids Leguminosae Source classification Cassia Cassia javanica L. Plants Other Flavonoids	Others
Afzelechin-(4α→8)-epiafzelechin is a Flavonoids product that can be isolated from the herbs of Cassia javanica .

HY-N1608

18-Norabieta-8,11,13-trien-4α-ol	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Populus euphratica Salicaceae	Others
18-Norabieta-8,11,13-trien-4α-ol (Compound 4) is a natural product that can be isolated from the resins of Populus euphratica .

HY-N11477

(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid	Triterpenes Structural Classification Terpenoids Source classification Rosaceae Plants Rubus ellipticus Smith	Glucosidase
(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid is a saponin that can be isolated from Rubus ellipticus var. obcordatus. (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid inhibits α-Glucosidase with an IC₅₀ of 1.68 mM .

HY-N3361

(3β,4α)-Lup-20(29)-ene-3,23-diol	Triterpenes Structural Classification Terpenoids Source classification Bursera simaruba (L.) Sarg. Plants Burseraceae	Others
(3β,4α)-Lup-20(29)-ene-3,23-diol (compound 11) is a natural lupane-type triterpenes betulinic acid with anti-tumor activity .

HY-N2882

*Apigenin-4'-α-L-rhamnoside*	Ranunculus sieboldii Miq. Structural Classification Flavonoids Flavones Source classification Ranunculaceae Plants	HBV
Apigenin-4'-α-L-rhamnoside is a potent inhibitor of HBV. Apigenin-4'-α-L-rhamnoside inhibits the secretory level of HBV surface antigen (HBsAg) in HepG2.2.15 cells .

HY-N1885

4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide	Structural Classification Terpenoids Sesquiterpenes Source classification Chloranthus erectus (Buchanan-Hamilton) Verdcourt Chloranthaceae Plants	Others
4alpha,8beta-Dihydroxyeudesm-7(11)-en-12,8-olide is a Sesquiterpenoids product that can be isolated from the herbs of Chloranthus elatior .

HY-N12147

*Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside*	Apocynaceae Structural Classification Polysaccharides Source classification Thevetia peruviana (Pers.) K. Schum. Plants Saccharides Monosaccharides	Others
Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside (Compound 12) is a cardiac glycoside that can be isolated from seeds of Thevetia peruvian. Cannogenol 3-O-β-gentiobiosyl-(1→4)-α-L-thevetoside shows cytotoxicity against SW1990 and MGC-803 cells (IC₅₀: 9.52 and 7.70 μM) .

HY-P2857

Amyloglucosidase, Aspergillus niger Amyloglucosidase; 1,4-α-D-Glucan glucohydrolase; Exo-1,4-α-glucosidase	Structural Classification Natural Products Microorganisms Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Others
Amyloglucosidase, Aspergillus niger is an enzyme derived from many sources including plants, animals and microorganisms, can be use for industrial production. Amyloglucosidase can be widely used for starch saccharification, brewing and distilling industry .

Species:	Human (6) Rhesus Macaque (2) Mouse (1)
Tag:	His (10) Tag Free (5) Strep (1) HA (1) Flag (2) Fc (1)
Source:	HEK293 (6) Sf9 insect cells (1) E. coli (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P76722

	AMY2A Protein, Human (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Human	HEK293
	AMY2A is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2A plays an important role in digesting dietary starch, and inhibiting AMY2A can lead to a decrease in postprandial blood glucose levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Human (HEK293, His) is the recombinant human-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag. The total length of AMY2A Protein, Human (HEK293, His) is 496 a.a., with molecular weight of 53-58 kDa.

HY-P7163

	Eotaxin-3/CCL26 Protein, Human rHuEotaxin-3/CCL26; C-C motif chemokine 26; MIP-4-alpha; TSC-1; SCYA26	Human	E. coli
	Eotaxin-3/CCL26 Protein, Human is a CC chemokine that binds to chemokine receptors CCR3 or CX3CR1 and is a chemotactic agent for eosinophils and basophils that mediates inflammatory responses. Eotaxin-3/CCL26 Protein, Human is a recombinant human Eotaxin-3/CCL26 (T24-L94) protein expressed by E. coli .

HY-P702103

	treZ Protein, Arthrobacter ramosus treZ; Malto-oligosyltrehalose trehalohydrolase; MTHase; 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase; Maltooligosyl trehalose trehalohydrolase	Others	E. coli
	The treZ protein plays a key role in glycan biosynthesis, especially trehalose biosynthesis. This enzyme helps catalyze the formation of trehalose, a disaccharide made of two glucose molecules linked by an α,α-1,1-glycosidic bond. treZ Protein, Arthrobacter ramosus is the recombinant treZ protein, expressed by E. coli , with tag free. The total length of treZ Protein, Arthrobacter ramosus is 575 a.a., .

HY-P702102

	treZ Protein, Arthrobacter ramosus (FLAG, His) treZ; Malto-oligosyltrehalose trehalohydrolase; MTHase; 4-alpha-D-((1->4)-alpha-D-glucano)trehalose trehalohydrolase; Maltooligosyl trehalose trehalohydrolase	Others	E. coli
	The treZ protein plays a key role in glycan biosynthesis, especially trehalose biosynthesis. This enzyme helps catalyze the formation of trehalose, a disaccharide made of two glucose molecules linked by an α,α-1,1-glycosidic bond. treZ Protein, Arthrobacter ramosus (FLAG, His) is the recombinant treZ protein, expressed by E. coli , with N-6*His, N-Flag labeled tag. The total length of treZ Protein, Arthrobacter ramosus (FLAG, His) is 575 a.a., .

HY-P702148

	Alpha amylase Protein, Bacillus licheniformis amyS; Alpha-amylase; 1; 4-alpha-D-glucan glucanohydrolase; BLA	Others	E. coli
	Alpha amylase Protein, Bacillus licheniformis is the recombinant Alpha amylase protein, expressed by E. coli , with tag free. The total length of Alpha amylase Protein, Bacillus licheniformis is 512 a.a., .

HY-P71203

	PHS Protein, Human (His) Pterin-4-Alpha-Carbinolamine Dehydratase; PHS; 4-Alpha-Hydroxy-Tetrahydropterin Dehydratase; Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha; DCoH; Dimerization Cofactor of HNF1; Phenylalanine Hydroxylase-Stimulating Protein; Pterin Carbinolamine Dehy	Human	E. coli
	PHS protein is crucial in tetrahydrobiopterin biosynthesis and has the dual function of hindering the formation of 7-pterin and promoting quinone-BH2. It also acts as a coactivator of HNF1A-dependent transcription, affecting HNF1A dimerization and enhancing its activity. PHS Protein, Human (His) is the recombinant human-derived PHS protein, expressed by E. coli , with N-6*His labeled tag.

HY-P702149

	Alpha amylase Protein, Bacillus licheniformis (His) amyS; Alpha-amylase; 1; 4-alpha-D-glucan glucanohydrolase; BLA	Others	E. coli
	Alpha amylase Protein, Bacillus licheniformis (His) is the recombinant Alpha amylase protein, expressed by E. coli , with N-6*His labeled tag. The total length of Alpha amylase Protein, Bacillus licheniformis (His) is 512 a.a., .

HY-P76723

	AMY2A Protein, Rhesus Macaque (HEK293, Fc) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76724

	AMY2A Protein, Rhesus Macaque (HEK293, His) Pancreatic alpha-amylase; PA; 1,4-alpha-D-glucan glucanohydrolase	Rhesus Macaque	HEK293
	AMY2B is a hydrolytic enzyme secreted by the pancreas that can hydrolyze α- 1,4-glycosidic bond, belonging to α- Members of the amylase family. AMY2B plays an important role in digesting dietary starch, and inhibiting AMY2B can lead to a decrease in postprandial blood sugar levels. Therefore, by regulating α- Amylase activity to control blood sugar level has therapeutic significance for diabetes, obesity and other diseases. AMY2A Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived AMY2A protein, expressed by HEK293 , with C-His labeled tag.

HY-P75606

	Eotaxin-3/CCL26 Protein, Human (sf9) C-C motif chemokine 26; MIP-4-alpha; TSC-1; SCYA26	Human	Sf9 insect cells
	Eotaxin-3/CCL26 Protein, Human (sf9) is a CC chemokine that binds to chemokine receptors CCR3 or CX3CR1 and is a chemotactic agent for eosinophils and basophils that mediates inflammatory responses. Eotaxin-3/CCL26 Protein, Human (sf9) is a recombinant human Eotaxin-3/CCL26 (M1-L94) protein expressed by Sf9 insect cells .

HY-P703513

	malQ Protein, Thermus thermophilus (Flag, His) 4-alpha-glucanotransferase; Amylomaltase; Disproportionating enzyme; D-enzyme; malQ; Thermus thermophilus; D-enzyme; Glycosyltransferase; Transferase; 2.4.1.25	Others	E. coli
	malQ Protein, Thermus thermophilus (Flag, His) is the recombinant malQ, expressed by E. coli , with His, Flag labeled tag. ,

HY-P70908

	EXTL2 Protein, Mouse (HEK293, His) Exostosin-like 2; Extl2; Alpha-1; 4-N-acetylhexosaminyltransferase EXTL2; Alpha-GalNAcT EXTL2; EXT-related protein 2; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase	Mouse	HEK293
	The EXTL2 protein is a key glycosyltransferase in heparan sulfate biosynthesis, responsible for overseeing the conversion of β-1-4-linked glucuronic acid (GlcA) and α-1-4-linked N-acetylglucosamine (GlcNAc) units Alternating sulfate chains are added to the nascent heparan. The function of this enzyme is critical for the complex and precise construction of heparan sulfate, a key component of various biological processes. EXTL2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EXTL2 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of EXTL2 Protein, Mouse (HEK293, His) is 288 a.a., with molecular weight of ~35.0 kDa.

HY-P701139

	HNF4A Protein, Human (His) FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14	Human	HEK293
	HNF 4 alpha, a nuclear transcription factor, forms homodimers to bind DNA. It regulates gene expression, including hepatocyte nuclear factor 1 alpha, impacting hepatic genes. Its involvement extends to liver, kidney, and intestinal development. Mutations associate with autosomal dominant non-insulin-dependent diabetes mellitus type I. The gene exhibits biased expression in the duodenum (RPKM 37.7) and colon (RPKM 32.8), among other tissues. HNF4A Protein, Human (His) is the recombinant human-derived HNF 4 alpha, expressed by HEK293 , with C-10*His labeled tag.

HY-P703445

	susB Protein, Bacteroides thetaiotaomicron Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; susB; Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Glycosidase; Hydrolase; 3.2.1.3	Others	E. coli
	susB Protein, Bacteroides thetaiotaomicron is the recombinant susB, expressed by E. coli , with tag Free labeled tag. ,

HY-P703446

	susB Protein, Bacteroides thetaiotaomicron (His, Strep) Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; susB; Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50); Glycosidase; Hydrolase; 3.2.1.3	Others	E. coli
	susB Protein, Bacteroides thetaiotaomicron (His, Strep) is the recombinant susB, expressed by E. coli , with Strep, His labeled tag. ,

HY-P77849

	ST3GAL4 Protein, Human (HEK293, His-HA) Sialyltransferase 4C; SIAT4; SIAT4C; SIAT4-C; ST3Gal IV; ST3GAL4; ST3GalA.2; ST-4; STZSIAT4; Alpha 2,3-ST 4; CGS23; CGS23FLJ46764; FLJ11867; Gal-NAc 6S; NANTA3; SAT3; SAT-3	Human	HEK293
	The ST3GAL4 protein is a β-galactoside α2-3 sialyltransferase essential for the sialylation of glycoproteins and glycolipids. It mediates hemostasis by sialylating VWF, preventing ASGPR recognition and clearance, and regulating platelet clearance. ST3GAL4 Protein, Human (HEK293, His-HA) is the recombinant human-derived ST3GAL4 protein, expressed by HEK293 , with C-His, N-HA labeled tag. The total length of ST3GAL4 Protein, Human (HEK293, His-HA) is 293 a.a., with molecular weight of ~35.4 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-132649S

α-Cholestane-d4
α-Cholestane-d₄ is the deuterium labeled α-Cholestane[1].

HY-B1204S

Histamine-α,α,β,β-d4 dihydrochloride
Histamine-α,α,β,β-d₄ (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-Y0245S

α-Cyanopyridine-d4
α-Cyanopyridine-d₄ is the deuterium labeled α-Cyanopyridine[1].

HY-118566S

5α-Androstenone-d4
5α-Androstenone-d₄ is the deuterium labeled 5α-Androstenone[1].

HY-154758S

6-Alpha-Methyl-Cortisol-d4
6-Alpha-Methyl-Cortisol-d₄ is deuterated labeled 6-Alpha-Methyl-Cortisol.

HY-154759S

6-Alpha-Methyl-Prednisolone-d4
6-Alpha-Methyl-Prednisolone-d₄ is deuterated labeled 6-Alpha-Methyl-Prednisolone.

HY-142127S

2-(α-D-Mannopyranosyl)-L-tryptophan-d4
2-(α-D-Mannopyranosyl)-L-tryptophan-d₄ is the deuterium labeled 2-(α-D-Mannopyranosyl)-L-tryptophan[1].

HY-N6710S

α-Zearalenol-d4
α-Zearalenol-d4 is a deuterated labeled α-Zearalenol . α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER), α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects .

HY-146638S

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4
5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d₄ is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82750

	alpha A Crystallin Antibody (YA2495) Acry 1; CRYA1; CRYAA; HspB4	WB, ICC/IF	Human, Mouse, Rat
	alpha A Crystallin Antibody (YA2495) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2495), targeting alpha A Crystallin, with a predicted molecular weight of 20 kDa (observed band size: 17 kDa). alpha A Crystallin Antibody (YA2495) can be used for WB, ICC/IF experiment in human, mouse, rat background.

HY-P81445

	*HNF 4 alpha* Antibody (YA1190)** TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; TCF-14; HNF4alpha	IHC-P	Human
	HNF 4 alpha Antibody (YA1190) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1190), targeting HNF 4 alpha. HNF 4 alpha Antibody (YA1190) can be used for IHC-P experiment in human background.

HY-P82317

	alpha Actinin 4 Antibody (YA2062) Alpha-actinin-4 ,Non-muscle alpha-actinin 4 ,ACTN4	WB, ICC/IF, IP	Human, Mouse, Rat
	alpha Actinin 4 Antibody (YA2062) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2062), targeting alpha Actinin 4, with a predicted molecular weight of 105 kDa (observed band size: 105 kDa). alpha Actinin 4 Antibody (YA2062) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-141126

Azido-PEG4-alpha-D-mannose		PROTAC Synthesis Azide
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154590

*2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine*		Azide
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154357

4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine		Azide
4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-152764

4’-α-C-Methyluridine		Nucleosides and their Analogs
4’-α-C-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

HY-152454

4’-α-C-Methylcytidine		Nucleosides and their Analogs
4’-α-C-Methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-154590

*2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine*		Nucleosides and their Analogs
2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154357

4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine		Nucleosides and their Analogs
4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-alpha-C-Azido-2’,3’-bis(O-t-butyldimethylsilyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-154358

4’-alpha-C-Allyl-2’,3’-bis(O-t-butyldimethylsilyl) uridine		Nucleosides and their Analogs
4’-alpha-C-Allyl-2’,3’-bis(O-t-butyldimethylsilyl) uridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .

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