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Results for "

E2 conjugating enzyme

" in MedChemExpress (MCE) Product Catalog:

2

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1

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47

Recombinant Proteins

7

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Cat. No. Compare Product Name Species Source
  • HY-P79449
    UbcH5b/UBE2D2 Protein, Human

    Ubiquitin-conjugating enzyme E2 D2; UBE2D2; (E3-independent) E2 ubiquitin-conjugating enzyme D2 (EC:2.3.2.24); E2 ubiquitin-conjugating enzyme D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kD

    		 Human E. coli
    The UbcH5b/UBE2D2 protein is an important cellular mediator that accepts ubiquitin from the E1 complex and catalyzes multifunctional “Lys-48”-linked polyubiquitination on target proteins. In addition to its catalytic role, it also concentrates and selectively degrades short-lived proteins and contributes to E6/E6-AP-induced ubiquitination of p53/TP53. UbcH5b/UBE2D2 Protein, Human is the recombinant human-derived UbcH5b/UBE2D2 protein, expressed by E. coli , with tag free. The total length of UbcH5b/UBE2D2 Protein, Human is 147 a.a., with molecular weight of ~16 kDa.
  • HY-P701488
    UB2E2 Protein, Human (Sf9)

    UBE2E2; Ubiquitin-conjugating enzyme E2 E2; E2 ubiquitin-conjugating enzyme E2; UbcH8; Ubiquitin carrier protein E2; Ubiquitin-protein ligase E2

    		 Human Sf9 insect cells
    The UB2E2 protein is a key ubiquitin-proteasome system participant, acting as an E2 ubiquitin-conjugating enzyme that accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to proteins. In vitro, UB2E2 exhibits multifunctionality by catalyzing polyubiquitination of “Lys-11,” “Lys-48,” and “Lys-63” linkages, suggesting its involvement in diverse cellular processes. UB2E2 Protein, Human (Sf9) is the recombinant human-derived UB2E2 protein, expressed by Sf9 insect cells , with tag free. The total length of UB2E2 Protein, Human (Sf9) is 200 a.a., .
  • HY-P701496
    UB2E2 Protein, Human (Sf9, His, Strep)

    UBE2E2; Ubiquitin-conjugating enzyme E2 E2; E2 ubiquitin-conjugating enzyme E2; UbcH8; Ubiquitin carrier protein E2; Ubiquitin-protein ligase E2

    		 Human Sf9 insect cells
    The UB2E2 protein is a key ubiquitin-proteasome system participant, acting as an E2 ubiquitin-conjugating enzyme that accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to proteins. In vitro, UB2E2 exhibits multifunctionality by catalyzing polyubiquitination of “Lys-11,” “Lys-48,” and “Lys-63” linkages, suggesting its involvement in diverse cellular processes. UB2E2 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UB2E2 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UB2E2 Protein, Human (Sf9, His, Strep) is 200 a.a., .
  • HY-P701350
    UBE2C Protein, Human (Sf9, His, Strep)

    UBE2C; Ubiquitin-conjugating enzyme E2 C; (E3-independent) E2 ubiquitin-conjugating enzyme C; E2 ubiquitin-conjugating enzyme C; UbcH10; Ubiquitin carrier protein C; Ubiquitin-protein ligase C

    		 Human Sf9 insect cells
    The UBE2C protein is a key ubiquitin-proteasome system component that acts as an E2 ubiquitin-conjugating enzyme and is the core of the covalent linkage of ubiquitin to target proteins. In vitro, UBE2C expertly promotes “Lys-11” and “Lys-48” linked polyubiquitination, demonstrating the versatility of ubiquitin chain formation. UBE2C Protein, Human (Sf9, His, Strep) is the recombinant human-derived UBE2C protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UBE2C Protein, Human (Sf9, His, Strep) is 178 a.a., .
  • HY-P79448
    UBE2R1/CDC34 Protein, Human (Sf9, His, Strep)

    Ubiquitin-conjugating enzyme E2 R1; CDC34; (E3-independent) E2 ubiquitin-conjugating enzyme R1 (EC:2.3.2.24); E2 ubiquitin-conjugating enzyme R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; Ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protei

    		 Human Sf9 insect cells
    The UBE2R1/CDC34 protein is an important ubiquitin-proteasome system component that functions as an E2 ubiquitin-conjugating enzyme, capable of proficiently accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to a variety of protein substrates. . In vitro, UBE2R1 efficiently mediates “Lys-48”-linked polyubiquitination. UBE2R1/CDC34 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UBE2R1/CDC34 protein, expressed by Sf9 insect cells , with N-Strep, N-His labeled tag. The total length of UBE2R1/CDC34 Protein, Human (Sf9, His, Strep) is 235 a.a., .
  • HY-P703042
    UBE2U Protein, Human (sf9, GST)

    Ubiquitin-conjugating enzyme E2 U; E2 ubiquitin-conjugating enzyme U; Ubiquitin carrier protein U; Ubiquitin-protein ligase U

    		 Human Sf9 insect cells
    UBE2U Protein, Human (sf9, GST) is the recombinant human-derived UBE2U, expressed by Sf9 insect cells , with GST labeled tag. ,
  • HY-P702065
    UB2D3 Protein, Human (Sf9, His, Strep)

    UBE2D3; Ubiquitin-conjugating enzyme E2 D3; (E3-independent) E2 ubiquitin-conjugating enzyme D3; E2 ubiquitin-conjugating enzyme D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3

    		 Human Sf9 insect cells
    The UBE2D3 protein is a key player in ubiquitination. It accepts ubiquitin from the E1 complex and covalently attaches it to a variety of proteins, demonstrating multifunctionality. It catalyzes "Lys-11" and "Lys-48" linked polyubiquitination in vitro, regulating protein ubiquitination patterns. UB2D3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UB2D3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UB2D3 Protein, Human (Sf9, His, Strep) is 146 a.a., .
  • HY-P701493
    UBE2O Protein, Human (Sf9, His, Strep)

    UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme; E2/E3 hybrid ubiquitin-protein ligase UBE2O; Ubiquitin carrier protein O; Ubiquitin-conjugating enzyme E2 O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O

    		 Human Sf9 insect cells
    UBE2O protein acts as a hybrid E2/E3 ubiquitin protein ligase capable of monoubiquitinating target proteins. It negatively regulates TRAF6-mediated NF-kappa-B activation independently of E2 activity. UBE2O Protein, Human (Sf9, His, Strep) is the recombinant human-derived UBE2O protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UBE2O Protein, Human (Sf9, His, Strep) is 1291 a.a., .
  • HY-P701494
    UBE2O Protein, Human (Sf9)

    UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme; E2/E3 hybrid ubiquitin-protein ligase UBE2O; Ubiquitin carrier protein O; Ubiquitin-conjugating enzyme E2 O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O

    		 Human Sf9 insect cells
    UBE2O protein acts as a hybrid E2/E3 ubiquitin protein ligase capable of monoubiquitinating target proteins. It negatively regulates TRAF6-mediated NF-kappa-B activation independently of E2 activity. UBE2O Protein, Human (Sf9) is the recombinant human-derived UBE2O protein, expressed by Sf9 insect cells , with tag free. The total length of UBE2O Protein, Human (Sf9) is 1291 a.a., .
  • HY-P701346
    UbcH6/UBE2E1 Protein, Human (Sf9)

    UBE2E1; Ubiquitin-conjugating enzyme E2 E1; (E3-independent) E2 ubiquitin-conjugating enzyme E1; E2 ubiquitin-conjugating enzyme E1; UbcH6; Ubiquitin carrier protein E1; Ubiquitin-protein ligase E1

    		 Human Sf9 insect cells
    The UbcH6/UBE2E1 protein is an important ubiquitination component that acts as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin in the E1 complex and catalyzing its covalent attachment to proteins. It is versatile and also facilitates covalent attachment of ISG15, playing a role in a variety of ubiquitin-like modifications. UbcH6/UBE2E1 Protein, Human (Sf9) is the recombinant human-derived UbcH6/UBE2E1 protein, expressed by Sf9 insect cells , with tag free. The total length of UbcH6/UBE2E1 Protein, Human (Sf9) is 192 a.a., .
  • HY-P701347
    UbcH6/UBE2E1 Protein, Human (Sf9, His, Strep)

    UBE2E1; Ubiquitin-conjugating enzyme E2 E1; (E3-independent) E2 ubiquitin-conjugating enzyme E1; E2 ubiquitin-conjugating enzyme E1; UbcH6; Ubiquitin carrier protein E1; Ubiquitin-protein ligase E1

    		 Human Sf9 insect cells
    The UbcH6/UBE2E1 protein is an important ubiquitination component that acts as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin in the E1 complex and catalyzing its covalent attachment to proteins. It is versatile and also facilitates covalent attachment of ISG15, playing a role in a variety of ubiquitin-like modifications. UbcH6/UBE2E1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UbcH6/UBE2E1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UbcH6/UBE2E1 Protein, Human (Sf9, His, Strep) is 192 a.a., .
  • HY-P701487
    UB2E3 Protein, Human (Sf9)

    UBE2E3; Ubiquitin-conjugating enzyme E2 E3; E2 ubiquitin-conjugating enzyme E3; UbcH9; Ubiquitin carrier protein E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3

    		 Human Sf9 insect cells
    UB2E3 protein is a key ubiquitin-proteasome system component. As an E2 ubiquitin-conjugating enzyme, it plays a crucial role in the attachment of ubiquitin to target proteins. In vitro, UB2E3 exhibits diverse catalytic abilities, promoting polyubiquitination of “Lys-11,” “Lys-48,” and “Lys-63” linkages, suggesting its involvement in diverse cellular processes. UB2E3 Protein, Human (Sf9) is the recombinant human-derived UB2E3 protein, expressed by Sf9 insect cells , with tag free. The total length of UB2E3 Protein, Human (Sf9) is 206 a.a., .
  • HY-P71412
    UBE2Z Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 Z; Uba6-Specific E2 conjugating enzyme 1; Use1; Ubiquitin Carrier Protein Z; Ubiquitin-Protein Ligase Z; UBE2Z; HOYS7

    		 Human E. coli
    UBE2Z Protein, a catalyst in ubiquitin conjugation, facilitates the covalent attachment of ubiquitin to target proteins. It serves as a specific substrate for UBA6 and is implicated in the regulation of apoptosis. UBE2Z Protein, Human (His) is the recombinant human-derived UBE2Z protein, expressed by E. coli , with N-6*His labeled tag. The total length of UBE2Z Protein, Human (His) is 246 a.a., with molecular weight of ~32.0 kDa.
  • HY-P701490
    UB2E3 Protein, Human (Sf9, His, Strep)

    UBE2E3; Ubiquitin-conjugating enzyme E2 E3; E2 ubiquitin-conjugating enzyme E3; UbcH9; Ubiquitin carrier protein E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3

    		 Human Sf9 insect cells
    UB2E3 protein is a key ubiquitin-proteasome system component. As an E2 ubiquitin-conjugating enzyme, it plays a crucial role in the attachment of ubiquitin to target proteins. In vitro, UB2E3 exhibits diverse catalytic abilities, promoting polyubiquitination of “Lys-11,” “Lys-48,” and “Lys-63” linkages, suggesting its involvement in diverse cellular processes. UB2E3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UB2E3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UB2E3 Protein, Human (Sf9, His, Strep) is 206 a.a., .
  • HY-P701495
    UB2Q2 Protein, Human (Sf9)

    UBE2Q2; Ubiquitin-conjugating enzyme E2 Q2; E2 ubiquitin-conjugating enzyme Q2; Ubiquitin carrier protein Q2; Ubiquitin-protein ligase Q2

    		 Human Sf9 insect cells
    The UB2Q2 protein is a component of the ubiquitin-proteasome system and functions as an E2 ubiquitin-conjugating enzyme, adept at accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to a variety of protein substrates. In vitro, UB2Q2 efficiently mediates “Lys-48”-linked polyubiquitination. UB2Q2 Protein, Human (Sf9) is the recombinant human-derived UB2Q2 protein, expressed by Sf9 insect cells , with tag free. The total length of UB2Q2 Protein, Human (Sf9) is 374 a.a., .
  • HY-P79451
    UbcH7/UBE2L3 Protein, Human

    Ubiquitin-conjugating enzyme E2 L3; UBE2L3; E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3; UBCE7

    		Human E. coli
    UbcH7/UBE2L3 is a unique ubiquitin-conjugating E2 enzyme that cooperates with HECT-type and RBR family E3 ligases and lacks intrinsic E3-independent reactivity with lysine. It uniquely works with RBR family E3 enzymes such as PRKN, RNF31 and ARIH1, acting like a RING-HECT hybrid. UbcH7/UBE2L3 Protein, Human is the recombinant human-derived UbcH7/UBE2L3 protein, expressed by E. coli , with tag free.
  • HY-P701348
    UbcH7/UBE2L3 Protein, Human (Sf9, His, Strep)

    UBE2L3; Ubiquitin-conjugating enzyme E2 L3; E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3

    		 Human Sf9 insect cells
    UbcH7/UBE2L3 is a unique ubiquitin-conjugating E2 enzyme that cooperates with HECT-type and RBR family E3 ligases and lacks intrinsic E3-independent reactivity with lysine. It uniquely works with RBR family E3 enzymes such as PRKN, RNF31 and ARIH1, acting like a RING-HECT hybrid. UbcH7/UBE2L3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UbcH7/UBE2L3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UbcH7/UBE2L3 Protein, Human (Sf9, His, Strep) is 153 a.a., .
  • HY-P701491
    UB2Q1 Protein, Human (His, Strep)

    UBE2Q1; Ubiquitin-conjugating enzyme E2 Q1; E2 ubiquitin-conjugating enzyme Q1; Protein NICE-5; Ubiquitin carrier protein Q1; Ubiquitin-protein ligase Q1

    		 Human E. coli
    Studies have shown that the UB2Q1 protein plays a key role in cellular processes by catalyzing the covalent attachment of ubiquitin to other proteins. In addition to its ubiquitination function, UB2Q1 may also be involved in female hormonal homeostasis. UB2Q1 Protein, Human (His, Strep) is the recombinant human-derived UB2Q1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of UB2Q1 Protein, Human (His, Strep) is 421 a.a., .
  • HY-P71408
    UBE2S Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 S; E2-EPF; Ubiquitin Carrier Protein S; Ubiquitin-conjugating enzyme E2-24 kDa; Ubiquitin-conjugating enzyme E2-EPF5; Ubiquitin-Protein Ligase S; UBE2S; E2EPF

    		 Human E. coli
    The UBE2S protein is critical in cellular ubiquitination, accepting ubiquitin from the E1 complex and catalyzing covalent attachment to various proteins.UBE2S is a key contributor to cell cycle regulation, catalyzing "Lys-11"-linked polyubiquitination, which is critical for anaphase-promoting complex/cyclosome (APC/C) function.UBE2S Protein, Human (GST) is the recombinant human-derived UBE2S protein, expressed by E.coli , with N-GST labeled tag.
  • HY-P79452
    UBE2N/Ubc13 Protein, Human (sf9, His, Strep)

    Ubiquitin-conjugating enzyme E2 N; UbcH13

    		 Human Sf9 insect cells
    The UBE2F protein accepts NEDD8 from the UBA3-NAE1 E1 complex and covalently links it to various target proteins in the ubiquitin-like NEDD8 conjugation pathway. The RBX2-UBE2F complex specifically interacts with the E3 ubiquitin ligase RBX2, but not RBX1, for the neddylation of specific targets, especially CUL5. UBE2N/Ubc13 Protein, Human (sf9, His, Strep) is the recombinant Rhesus Macaque, cynomolgus-derived UBE2N/Ubc13 protein, expressed by Sf9 insect cells , with N-8*His, N-Strep labeled tag. The total length of UBE2N/Ubc13 Protein, Human (sf9, His, Strep) is 151 a.a., .
  • HY-P71404
    UBE2J2 Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 J2; Non-Canonical Ubiquitin-conjugating enzyme 2; NCUBE-2; UBE2J2; NCUBE2

    		 Human E. coli
    The UBE2J2 protein plays a crucial role in cellular processes by catalyzing the covalent attachment of ubiquitin to other proteins. Its function is involved in the selective degradation of misfolded membrane proteins extending into the endoplasmic reticulum (ERAD), as suggested by the similarity of related processes. UBE2J2 Protein, Human (GST) is the recombinant human-derived UBE2J2 protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P77272
    UBE2W Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 W; UBC-16; Ubiquitin-protein ligase W; UBC16

    		 Human E. coli
    UBE2W protein is a multifunctional ubiquitin-conjugating enzyme that accepts ubiquitin in the E1 complex and catalyzes its covalent attachment to different substrates. Notably, UBE2W uniquely monoubiquitylates the N-terminus, including ATXN3, MAPT/TAU, POLR2H/RPB8, and STUB1/CHIP, showing specificity for disordered N-termini. UBE2W Protein, Human (His) is the recombinant human-derived UBE2W protein, expressed by E. coli , with N-His labeled tag.
  • HY-P71402
    UBE2H Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 H; UbcH2; Ubiquitin Carrier Protein H; Ubiquitin-conjugating enzyme E2-20K; Ubiquitin-Protein Ligase H; UBE2H

    		 Human E. coli
    UBE2H Protein, a crucial participant in cellular ubiquitination, transfers ubiquitin from the E1 complex to various proteins, including MAEA of the CTLH E3 ubiquitin-protein ligase complex. Versatile in vitro, UBE2H catalyzes both 'Lys-11'- and 'Lys-48'-linked polyubiquitination, showcasing its involvement in diverse ubiquitin-related processes. Notably, it demonstrates the capability to ubiquitinate histone H2A in vitro. UBE2H Protein, Human (GST) is the recombinant human-derived UBE2H protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2H Protein, Human (GST) is 183 a.a., with molecular weight of ~50.0 kDa.
  • HY-P71405
    UBE2K Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 K; Huntingtin-Interacting Protein 2; HIP-2; Ubiquitin Carrier Protein; Ubiquitin-conjugating enzyme E2-25 kDa; Ubiquitin-conjugating enzyme E2(25K); Ubiquitin-conjugating enzyme E2-25K; Ubiquitin-Protein Ligase; UBE2K; HIP2; LIG

    		 Human E. coli
    UBE2K protein is an important component of the ubiquitin-proteasome system and functions as an E2 ubiquitin-conjugating enzyme, which is critical for attaching ubiquitin to different substrates. In vitro, UBE2K catalyzes "Lys-48" linked polyubiquitin chains, specifically in the presence or absence of the BRCA1-BARD1 E3 ligase complex. UBE2K Protein, Human (GST) is the recombinant human-derived UBE2K protein, expressed by E. coli , with N-GST labeled tag.
  • HY-P703055
    UBE2D2 Protein, Xenopus (His)

    UBC4; E2 ubiquitin-conjugating enzyme; ubE2d1.L; E2(17)kb1

    		Xenopus laevis E. coli
    UBE2D2 Protein, Xenopus (His) is the recombinant Xenopus laevis-derived UBE2D2, expressed by E. coli , with His labeled tag. ,
  • HY-P71406
    UBE2M Protein, Human

    NEDD8-conjugating enzyme Ubc12; NEDD8 carrier protein; NEDD8 protein ligase; Ubiquitin-conjugating enzyme E2 M; UBC12; UBE2M;

    		Human E. coli
    UBE2M Protein is a crucial mediator in the ubiquitin-like protein NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex, covalently attaching it to target proteins like CUL1, CUL2, CUL3, and CUL4, particularly interacting with the E3 ubiquitin ligase RBX1. This specificity in neddylating specific targets suggests a pivotal role in regulating cellular processes, notably contributing to cell proliferation. UBE2M Protein, Human is the recombinant human-derived UBE2M protein, expressed by E. coli , with tag free. The total length of UBE2M Protein, Human is 183 a.a., with molecular weight of 19-25.0 kDa.
  • HY-P702064
    UB2L5 Protein, Human (Sf9)

    UBE2L5; Ubiquitin-conjugating enzyme E2 L5; Ubiquitin-protein ligase L5

    		 Human Sf9 insect cells
    QDPR Protein, operating as a catalyst, converts quinonoid dihydrobiopterin into tetrahydrobiopterin, crucial for balancing biopterin cofactors in cellular metabolism. Tetrahydrobiopterin serves as an essential coenzyme in neurotransmitter synthesis and phenylalanine breakdown, emphasizing QDPR's regulatory role in diverse metabolic pathways. UB2L5 Protein, Human (Sf9) is the recombinant human-derived UB2L5 protein, expressed by Sf9 insect cells , with tag free. The total length of UB2L5 Protein, Human (Sf9) is 153 a.a., .
  • HY-P77271
    UBE2G1 Protein, Human

    Ubiquitin-conjugating enzyme E2 G1; E217K; UBC7; UBE2G1; UBE2G

    		 Human E. coli
    UBE2G1 Protein, a crucial ubiquitin-proteasome system player, acts as an E2 ubiquitin-conjugating enzyme, facilitating ubiquitin attachment to diverse protein substrates. In vitro, UBE2G1 demonstrates catalytic competence in 'Lys-48' and 'Lys-63'-linked polyubiquitination reactions. This multifaceted enzyme is implicated in potential roles, including the degradation of muscle-specific proteins, emphasizing its involvement in cellular processes related to protein turnover. Additionally, UBE2G1 mediates the polyubiquitination of CYP3A4, a cytochrome P450 enzyme, underscoring its significance in regulating specific cellular pathways. UBE2G1 Protein, Human is the recombinant human-derived UBE2G1 protein, expressed by E. coli, with tag free. The total length of UBE2G1 Protein, Human is 170 a.a., with molecular weight of ~19.5 kDa.
  • HY-P701498
    UE2NL Protein, Human (Sf9)

    UBE2NL; Putative ubiquitin-conjugating enzyme E2 N-like; Epididymis tissue protein Li 174

    		 Human Sf9 insect cells
    The UE2NL protein is expressed exclusively in the epididymis and regulates molecular processes in this reproductive tissue. As part of a family of ubiquitin-conjugating enzymes, UE2NL may be involved in ubiquitin-mediated signaling pathways affecting post-translational protein modifications in the epididymal microenvironment. UE2NL Protein, Human (Sf9) is the recombinant human-derived UE2NL protein, expressed by Sf9 insect cells , with tag free. The total length of UE2NL Protein, Human (Sf9) is 152 a.a., .
  • HY-P701500
    UEVLD Protein, Human (Sf9)

    UEVLD; Ubiquitin-conjugating enzyme E2 variant 3; UEV-3; EV and lactate/malate dehydrogenase domain-containing protein

    		 Human Sf9 insect cells
    UEVLD proteins are considered potential negative regulators of polyubiquitination, possibly controlling the ubiquitin-proteasome system. Its ability to form homodimers suggests that it has self-interacting properties, which may contribute to its role in regulating polyubiquitin chains. UEVLD Protein, Human (Sf9) is the recombinant human-derived UEVLD protein, expressed by Sf9 insect cells , with tag free. The total length of UEVLD Protein, Human (Sf9) is 470 a.a., .
  • HY-P70998
    UBE2D3 Protein, Human
    2 Publications Verification

    Ubiquitin-conjugating enzyme E2 D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3; UBE2D3 and UBCH5C.

    		 Human E. coli
    Ubiquitin-conjugating enzyme E2 D3 (UBE2D3) is an E3 ubiquitin protein ligase. UBE2D3 is able to accept ubiquitin from specific E2 ubiquitin-conjugating enzymes and transfer it to substrates, often promoting its degradation by the proteasome. UBE2D3 Protein, Human is the recombinant human-derived UBE2D3 protein, expressed by E. coli , with tag free. The total length of UBE2D3 Protein, Human is 147 a.a., with molecular weight of ~15.0 kDa.
  • HY-P702066
    UB2L5 Protein, Human (Sf9, His, Strep)

    UBE2L5; Ubiquitin-conjugating enzyme E2 L5; Ubiquitin-protein ligase L5

    		 Human Sf9 insect cells
    QDPR Protein, operating as a catalyst, converts quinonoid dihydrobiopterin into tetrahydrobiopterin, crucial for balancing biopterin cofactors in cellular metabolism. Tetrahydrobiopterin serves as an essential coenzyme in neurotransmitter synthesis and phenylalanine breakdown, emphasizing QDPR's regulatory role in diverse metabolic pathways. UB2L5 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UB2L5 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UB2L5 Protein, Human (Sf9, His, Strep) is 153 a.a., .
  • HY-P701497
    UE2NL Protein, Human (Sf9, His, Strep)

    UBE2NL; Putative ubiquitin-conjugating enzyme E2 N-like; Epididymis tissue protein Li 174

    		 Human Sf9 insect cells
    The UE2NL protein is expressed exclusively in the epididymis and regulates molecular processes in this reproductive tissue. As part of a family of ubiquitin-conjugating enzymes, UE2NL may be involved in ubiquitin-mediated signaling pathways affecting post-translational protein modifications in the epididymal microenvironment. UE2NL Protein, Human (Sf9, His, Strep) is the recombinant human-derived UE2NL protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UE2NL Protein, Human (Sf9, His, Strep) is 152 a.a., .
  • HY-P701499
    UEVLD Protein, Human (Sf9, His, Strep)

    UEVLD; Ubiquitin-conjugating enzyme E2 variant 3; UEV-3; EV and lactate/malate dehydrogenase domain-containing protein

    		 Human Sf9 insect cells
    UEVLD proteins are considered potential negative regulators of polyubiquitination, possibly controlling the ubiquitin-proteasome system. Its ability to form homodimers suggests that it has self-interacting properties, which may contribute to its role in regulating polyubiquitin chains. UEVLD Protein, Human (Sf9, His, Strep) is the recombinant human-derived UEVLD protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UEVLD Protein, Human (Sf9, His, Strep) is 470 a.a., .
  • HY-P71407
    UBE2R2 Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 R2; Ubiquitin Carrier Protein R2; Ubiquitin-conjugating enzyme E2-CDC34B; Ubiquitin-Protein Ligase R2; UBE2R2; CDC34B; UBC3B

    		 Human E. coli
    UBE2R2 Protein, a key element in the ubiquitin-proteasome system, operates as an E2 ubiquitin-conjugating enzyme. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to diverse protein substrates. In vitro, UBE2R2 displays versatile catalytic activity, facilitating both monoubiquitination and 'Lys-48'-linked polyubiquitination reactions. This implies its potential involvement in various cellular processes, including the targeted degradation of proteins, suggesting a role in the regulation of substrates like katenin. UBE2R2 Protein, Human (His) is the recombinant human-derived UBE2R2 protein, expressed by E. coli, with N-6*His labeled tag. The total length of UBE2R2 Protein, Human (His) is 238 a.a., with molecular weight of ~37.0 kDa.
  • HY-P71401
    UBE2G2 Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 G2; Ubiquitin Carrier Protein G2; Ubiquitin-Protein Ligase G2; UBE2G2

    		 Human E. coli
    UBE2G2 Protein, a vital ubiquitination component, accepts ubiquitin from the E1 complex, catalyzing its covalent attachment to various proteins, with a preference for 'Lys-48'-linked polyubiquitination. Its specificity in shaping ubiquitin chains underscores its role in cellular processes. Intricately associated with endoplasmic reticulum-associated degradation (ERAD), UBE2G2 maintains cellular homeostasis by regulating protein turnover. Indispensable for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase, it facilitates subsequent proteasomal degradation. UBE2G2 Protein, Human (GST) is the recombinant human-derived UBE2G2 protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2G2 Protein, Human (GST) is 165 a.a., with molecular weight of ~43.0 kDa.
  • HY-P71398
    UBE2B Protein, Human (HEK293, His)

    Ubiquitin-conjugating enzyme E2 B; RAD6 Homolog B; HR6B; hHR6B; Ubiquitin Carrier Protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-Protein Ligase B; UBE2B; RAD6B

    		 Human HEK293
    UBE2B Protein, a key ubiquitination player, functions as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin from the E1 complex and catalyzing covalent attachment to proteins. Teaming with BRE1 (RNF20 and/or RNF40) E3 enzyme, UBE2B plays a pivotal role in transcriptional regulation by catalyzing histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). This modification tags various epigenetic processes and is essential for H3K4me and H3K79me formation. UBE2B exhibits versatile ubiquitin chain linkages, mediating 'Lys-11', 'Lys-48', and 'Lys-63'-linked polyubiquitination in vitro. It also plays a crucial role in postreplication repair of UV-damaged DNA, forming the UBE2B-RAD18 ubiquitin ligase complex with RAD18 E3 ligase, which mono-ubiquitinates DNA-associated PCNA on 'Lys-164'. The diverse functions of UBE2B suggest potential involvement in neurite outgrowth. UBE2B Protein, Human (HEK293, His) is the recombinant human-derived UBE2B protein, expressed by HEK293, with C-6*His labeled tag. The total length of UBE2B Protein, Human (HEK293, His) is 152 a.a., with molecular weight of ~17.0 kDa.
  • HY-P71399
    UBE2D1 Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 D1; Stimulator of Fe transport; SFT; UBC4/5 homolog; UbcH5; Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase D1; SFT; UBC5A; UBCH5; UBCH5A

    		 Human E. coli
    UBE2D1 Protein, crucial in cellular processes, accepts ubiquitin from the E1 complex, preferentially catalyzing 'Lys-48'-linked polyubiquitination in vitro, showcasing versatility. It mediates selective degradation of short-lived and aberrant proteins and participates in E6/E6-AP-induced p53/TP53 ubiquitination. UBE2D1 facilitates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6, and TRIM63/MURF1. It ubiquitinates STUB1-associated HSP90AB1 in vitro, highlighting involvement in cellular pathways. Lacking inherent specificity for any ubiquitin lysine residue, UBE2D1's dynamic nature in ubiquitin modification processes is notable. Its essential role in viral activation of IRF3 and mediation of CYP3A4 polyubiquitination emphasizes multifaceted contributions to cellular function. UBE2D1 Protein, Human (GST) is the recombinant human-derived UBE2D1 protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2D1 Protein, Human (GST) is 147 a.a., with molecular weight of ~40.0 kDa.
  • HY-P71403
    UBE2I Protein, Human (GST)

    SUMO-conjugating enzyme UBC9; SUMO-Protein Ligase; Ubiquitin Carrier Protein 9; Ubiquitin Carrier Protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-Protein Ligase I; p18; UBE2I; UBC9; UBCE9

    		 Human E. coli
    UBE2I Protein, a key participant in protein sumoylation, accepts ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4, and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex. Teaming up with E3 ligases like RANBP2, CBX4, and ZNF451, UBE2I catalyzes the covalent attachment of these SUMO proteins to target proteins, including critical substrates FOXL2 and KAT5. Its enzymatic activity extends to forming poly-SUMO chains, influencing diverse cellular processes and playing a pivotal role in specific protein modifications, such as sumoylation of p53/TP53 at 'Lys-386' and ERCC6. UBE2I Protein, Human (GST) is the recombinant human-derived UBE2I protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2I Protein, Human (GST) is 158 a.a., with molecular weight of ~40.0 kDa.
  • HY-P71409
    UBE2T Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 T; Cell Proliferation-Inducing Gene 50 Protein; Ubiquitin Carrier Protein T; Ubiquitin-Protein Ligase T; UBE2T

    		 Human E. coli
    UBE2T Protein, an essential ubiquitination component, serves as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to proteins. This multifaceted enzyme catalyzes monoubiquitination, crucial in MMC-induced DNA repair processes. Its significance is highlighted by specific association with the Fanconi anemia complex, collaborating with FANCL for FANCD2 monoubiquitination in the DNA damage response pathway. Beyond DNA repair, UBE2T mediates monoubiquitination of FANCL and FANCI and potentially contributes to BRCA1 ubiquitination and degradation. In vitro, UBE2T promotes various polyubiquitination types, showcasing involvement in diverse ubiquitin-dependent processes. UBE2T Protein, Human (His) is the recombinant human-derived UBE2T protein, expressed by E. coli, with N-6*His labeled tag. The total length of UBE2T Protein, Human (His) is 197 a.a., with molecular weight of 25-30 kDa.
  • HY-P71400
    UBE2D4 Protein, Human (GST)

    Ubiquitin-conjugating enzyme E2 D4; HBUCE1; Ubiquitin Carrier Protein D4; Ubiquitin-Protein Ligase D4; UBE2D4; UBCH5D

    		 Human E. coli
    UBE2D4 Protein, a vital ubiquitin-proteasome system component, acts as an E2 ubiquitin-conjugating enzyme, accepting ubiquitin from the E1 complex and catalyzing its covalent attachment to proteins. In vitro, UBE2D4 demonstrates versatility by promoting polyubiquitination with all seven ubiquitin Lys residues, potentially favoring 'Lys-11' and 'Lys-48'-linked polyubiquitination. This dynamic ubiquitin chain range suggests UBE2D4's involvement in diverse cellular processes and regulatory pathways, highlighting its significance in the intricate network of protein degradation and turnover. UBE2D4 Protein, Human (GST) is the recombinant human-derived UBE2D4 protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2D4 Protein, Human (GST) is 147 a.a., with molecular weight of ~40.0 kDa.
  • HY-P71397
    UBE2A Protein, Human (GST-His)

    Ubiquitin-conjugating enzyme E2 A; RAD6 Homolog A; HR6A; hHR6A; Ubiquitin Carrier Protein A; Ubiquitin-Protein Ligase A; UBE2A; RAD6A

    		 Human E. coli
    UBE2A cooperates with the E3 enzyme BRE1 to promote the attachment of ubiquitin to proteins, specifically histone H2B at "Lys-120", forming H2BK120ub1. This modification serves as a tag for transcriptional activation, RNA polymerase II elongation, telomeric silencing, and is critical for the formation of H3K4me and H3K79me. UBE2A Protein, Human (GST-His) is the recombinant human-derived UBE2A protein, expressed by E. coli , with N-6*His, N-GST labeled tag. The total length of UBE2A Protein, Human (GST-His) is 152 a.a., with molecular weight of ~52.0 kDa.
  • HY-P701489
    UB2V1 Protein, Human (Sf9)

    UBE2V1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; CROC-1; TRAF6-regulated IKK activator 1 beta Uev1A

    		 Human Sf9 insect cells
    The UBE2V1 protein does not have intrinsic ubiquitin ligase activity and can cooperate with UBE2N to synthesize non-canonical polyubiquitin chains linked through Lys-63. This type of polyubiquitination activates IKK and mediates NF-kappa-B activation, thereby affecting transcriptional activation, cell cycle progression, and DNA repair. UB2V1 Protein, Human (Sf9) is the recombinant human-derived UB2V1 protein, expressed by Sf9 insect cells , with tag free. The total length of UB2V1 Protein, Human (Sf9) is 146 a.a., .
  • HY-P701501
    UB2V1 Protein, Human (Sf9, His, Strep)

    UBE2V1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; CROC-1; TRAF6-regulated IKK activator 1 beta Uev1A

    		 Human Sf9 insect cells
    The UBE2V1 protein does not have intrinsic ubiquitin ligase activity and can cooperate with UBE2N to synthesize non-canonical polyubiquitin chains linked through Lys-63. This type of polyubiquitination activates IKK and mediates NF-kappa-B activation, thereby affecting transcriptional activation, cell cycle progression, and DNA repair. UB2V1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived UB2V1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of UB2V1 Protein, Human (Sf9, His, Strep) is 146 a.a., .
  • HY-P71020
    UBE2L6 Protein, Human (His)

    Ubiquitin/ISG15-conjugating enzyme E2 L6; Retinoic Acid-Induced Gene B Protein; RIG-B; UbcH8; Ubiquitin Carrier Protein L6; Ubiquitin-Protein Ligase L6; UBE2L6; UBCH8

    		 Human E. coli
    The UBE2L6 protein plays a key role in cell regulation by catalyzing the covalent attachment of ubiquitin or ISG15 to other proteins. Notably, it plays a role in E6/E6-AP-induced ubiquitination of p53/TP53, a core process in regulating cellular responses to stress and DNA damage. UBE2L6 Protein, Human (His) is the recombinant human-derived UBE2L6 protein, expressed by E. coli , with C-6*His labeled tag. The total length of UBE2L6 Protein, Human (His) is 153 a.a., with molecular weight of ~17.0 kDa.
  • HY-P71410
    UBE2V1 Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 Variant 1; UEV-1; CROC-1; TRAF6-Regulated IKK Activator 1 Beta Uev1A; UBE2V1; CROC1; UBE2V; UEV1; P/OKcl.19

    		 Human E. coli
    The UBE2V1 protein does not have intrinsic ubiquitin ligase activity and can cooperate with UBE2N to synthesize non-canonical polyubiquitin chains linked through Lys-63. This type of polyubiquitination activates IKK and mediates NF-kappa-B activation, thereby affecting transcriptional activation, cell cycle progression, and DNA repair. UBE2V1 Protein, Human (His) is the recombinant human-derived UBE2V1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of UBE2V1 Protein, Human (His) is 146 a.a., with molecular weight of ~17.0 kDa.
  • HY-P71411
    UBE2V2 Protein, Human (His)

    Ubiquitin-conjugating enzyme E2 Variant 2; DDVit 1; Enterocyte Differentiation-Associated Factor 1; EDAF-1; Enterocyte Differentiation-Promoting Factor 1; EDPF-1; MMS2 Homolog; Vitamin D3-Inducible Protein; UBE2V2; MMS2; UEV2

    		 Human E. coli
    UBE2V2 protein lacks independent ubiquitin ligase activity and forms a functional heterodimer with UBE2N. Together, they catalyze nonclassical polyubiquitin chain synthesis ("Lys-63"), distinct from proteasome-driven degradation. UBE2V2 Protein, Human (His) is the recombinant human-derived UBE2V2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of UBE2V2 Protein, Human (His) is 145 a.a., with molecular weight of ~18.0 kDa.

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