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Peptide Synthesis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (2) ADC Cytotoxin (2) ADC Linker (6) Amino Acid Derivatives (70) Angiotensin Receptor (3) Antibiotic (8) Apoptosis (5) Bacterial (15) Biochemical Assay Reagents (10) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) FAK (1) Fungal (2) Integrin (1) Interleukin Related (2) Isotope-Labeled Compounds (3) Melanocortin Receptor (2) mTOR (1) PI3K (1) PROTAC Linkers (4) Protease Activated Receptor (PAR) (2) Radionuclide-Drug Conjugates (RDCs) (2) Reactive Oxygen Species (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (5) Endocrinology (6) Infection (20) Inflammation/Immunology (6) Metabolic Disease (7) Neurological Disease (5)
Click Chemistry:	Azide (3) Alkynes (2)

137

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

115

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: DNA/RNA Synthesis Formyl Peptide Receptor (FPR) CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-133803

Z-Ala-Ala-OH	Amino Acid Derivatives	Others
Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis .

HY-D0177

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate	Biochemical Assay Reagents	Others
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and can be utilized in solid phase synthesis test .

HY-Y1636

Fmoc-Arg(Pbf)-OH	Amino Acid Derivatives	Others
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .

HY-131092

H-Asn-Arg-OH	Others	Others
H-Asn-Arg-OH is used for the solid-phase peptide synthesis.

HY-131094

H-Gly-D-Tyr-OH	Others	Others
H-Gly-D-Tyr-OH is used for the the solid-phase peptide synthesis.

HY-W048209

Fmoc-Lys(Palmitoyl)-OH	Amino Acid Derivatives	Others
Fmoc-Lys(Palmitoyl)-OH is a Fmoc-amino acid with long alkyl chains. Fmoc-Lys(Palmitoyl)-OH can be used for peptide synthesis .

HY-W090942

Z-Gly-Gly-Phe-OH	Amino Acid Derivatives	Others
Z-Gly-Gly-Phe-OH is an active compound. Z-Gly-Gly-Phe-OH can be used for the synthesis of enzymic peptide .

HY-131091

Boc-Glu(OBzl)-OSu	Amino Acid Derivatives	Others
Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.

HY-W088805

Fmoc-NIP-OH Fmoc-3-carboxypiperidine	Amino Acid Derivatives	Others
Fmoc-NIP-OH (Fmoc-3-carboxypiperidine) is a Fmoc-protected amino acid derivative commonly used in peptide synthesis .

HY-78927

N-Boc-L-Prolinal	Amino Acid Derivatives	Others
N-Boc-L-Prolinal is a proline with a Boc protecting group, which can be used to synthesize biologically active peptide mimetics, such as the synthesis of Dolastatin 10 (HY-15580) analogs with anti-colon cancer activity .

HY-Y1169

Fmoc-Asp(OtBu)-OH 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate; Fmoc-L-Asp(OtBu)-OH	Amino Acid Derivatives	Others
Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .

HY-125586

β-Amanitin	DNA/RNA Synthesis ADC Cytotoxin	Cancer
β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .

HY-151783

DAPOA	ADC Linker	Others
DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151783A

DAPOA (DCHA)	ADC Linker	Others
DAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-41121

Boc-L-Ala-OH 1 Publications Verification Boc-Ala-OH	Amino Acid Derivatives	Others
Boc-L-Ala-OH (Boc-Ala-OH) shows excellent affinity with ATP. Boc-L-Ala-OH contains an amino acid moiety, and an acylamide bond like that of the peptide and protein .

HY-164166

Fmoc-Sar-Sar-Sar-OH	Biochemical Assay Reagents	Others
Fmoc-Sar-Sar-Sar-OH is a small molecule polypeptide composed of four sarcosine residues, in which the N-terminus of the peptide chain is protected by Fmoc. Fmoc-Sar-Sar-Sar-OH can be used for peptide synthesis or synthesis of drug-peptide ligand conjugates .

HY-W540122

Fmoc-PNA-C(Bhoc)-OH	Biochemical Assay Reagents	Others
Fmoc-PNA-C(Bhoc)-OH is a peptide nucleic acid monomers, and can be used in the synthesis of peptide nucleic acid compounds .

HY-120286

K-13	Others	Others
K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.

HY-35028

Boc-Glu-Ofm	Amino Acid Derivatives	Others
Boc-Glu-Ofm is a peptide. Boc-Glu-Ofm has been used for the synthesis of ester insulin and cyclic peptide mixtures .

HY-P3326

Targeting the bacterial sliding clamp peptide 46	Bacterial	Infection
Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.

HY-138106

Fmoc-D-Cit-OH	Amino Acid Derivatives	Others
Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50-(CF3)2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity .

HY-W008555

Fmoc-N-Me-Ile-OH	Amino Acid Derivatives	Others
Fmoc-N-Me-Ile-OH is a used in peptide synthesis .

HY-W013750

Fmoc-Arg-OH Fmoc-L-Arginine	Amino Acid Derivatives	Others
Fmoc-Arg-OH (Fmoc-L-Arginine), an Fmoc modified Arginine, is a used in peptide synthesis.

HY-131095

Z-Glu-Tyr-OH	Amino Acid Derivatives	Others
Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support .

HY-W009876

9-Fluorenylmethanol	Biochemical Assay Reagents	Others
9-Fluorenylmethanol is an N-protecting reagent that can be used in peptide synthesis .

HY-60265

Boc-D-Cyclopropylglycine	Amino Acid Derivatives	Others
Boc-D-Cyclopropylglycine is a small molecule peptide, it can be used for compounds synthesis .

HY-W140465

L-Homotyrosine	Others	Others
L-Homotyrosine is a tyrosine derivative that can be used for solid-phase peptide synthesis .

HY-119523

Disuccinimidyl sebacate 1 Publications Verification DSSeb; Sebacic acid bis N-succinimidyl ester	Biochemical Assay Reagents	Others
Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .

HY-41912B

Boc-D-norleucine Boc-D-Nle-OH; N-BOC-D-norleucine	Amino Acid Derivatives	Others
Boc-D-norleucine (Boc-D-Nle-OH) is a leucine derivative that can be used for peptide synthesis .

HY-P4198

Fmoc-N(Me)-Sar10 Fmoc-Sar10	Biochemical Assay Reagents	Others
Fmoc-N(Me)-Sar10 can be used for synthesis of peptide ligand-agent conjugates .

HY-P2392

Fmoc-Ala-Thr(psi(Me,Me)pro)-OH	Amino Acid Derivatives	Others
Fmoc-Ala-Thr(psi(Me,Me))-OH is an Fmoc protected alanine derivative and can be used for peptide synthesis.

HY-W048682

Fmoc-1-methyl-L-histidine	Amino Acid Derivatives	Others
Fmoc-1-methyl-L-histidine is a Fmoc protected amino acid and can be used as an intermediate for peptide synthesis .

HY-79404A

Boc-beta-t-butyl-d-alanine	Amino Acid Derivatives	Others
Boc-beta-t-butyl-d-alanine is an intermediate, can be used in the synthesis of peptides and other amino acids .

HY-W016413

4-(Hydroxymethyl)phenoxyacetic acid	Others	Others
4-(Hydroxymethyl)phenoxyacetic acid is an acid-labile resin linkage agent for use in solid phase peptide synthesis .

HY-W338516

Fmoc-L-Homoarginine hydrochloride	Amino Acid Derivatives	Others
Fmoc-L-Homoarginine hydrochloride is a derivative of amino acid with protecting groups. Fmoc-L-Homoarginine hydrochloride can be used for synthesis of homoarginine containing peptide .

HY-W048199

(S)-N-FMoc-2-(6'-heptenyl)alanine	Amino Acid Derivatives	Others
(S)-N-FMoc-2-(6'-heptenyl)alanine is a amino acid, which can be used in peptide synthesis .

HY-W036160

N-Fmoc-O-ethyl-L-homoserine	Amino Acid Derivatives	Others
N-Fmoc-O-ethyl-L-homoserine is an homoserine derivative, can be used in cyclic peptide compounds synthesis, as a reducing reagent .

HY-Y0912

HBTU N-HBTU	Others	Others
HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis .

HY-W419374

ivDde-Lys(Fmoc)-OH	Amino Acid Derivatives	Others
ivDde-Lys(Fmoc)-OH is a derivative of amino acid with protecting groups. ivDde-Lys(Fmoc)-OH can be used for peptide synthesis .

HY-W562116

Boc-Lys(ivdde)-OH	Amino Acid Derivatives	Others
Boc-Lys(ivdde)-OH is a derivative of amino acid. Boc-Lys(ivdde)-OH can be used for synthesis of lysine containing peptide .

HY-N2403

Dihydrolycorine 1 Publications Verification	Others	Neurological Disease
Dihydrolycorine, isolated from Lycoris radiate Herb, is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step .

HY-W012000

Boc-N-methyl-L-isoleucine Boc-N-Me-Ile-OH	Amino Acid Derivatives	Others
Boc-N-methyl-L-isoleucine (Boc-N-Me-Ile-OH) is a peptide products and can be used as a precursor in organic synthesis and pharmaceuticals .

HY-W142064

Fmoc-L-photo-proline	Antibiotic	Others
Fmoc-L-photo-proline is a photo-crosslinking amino acid which can be incorporated into synthetic peptides using solid-phase Fmoc chemistry. Fmoc-L-photo-proline can synthesis of cyclic peptidomimetic antibiotic and be used for preparation of diverse peptide-based photoaffinity probes research .

HY-W002327

Fmoc-Asn(Trt)-OH	Biochemical Assay Reagents	Others
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .

HY-34738

Boc-β-Ala-ol 3-(Boc-amino)-1-propanol	Amino Acid Derivatives	Others
Boc-β-Ala-ol (3-(Boc-amino)-1-propanol) is an alanine derivative with a Boc protecting group at the N-terminus, which can be used to synthesize bioactive peptide mimics, such as Nα-Benzoyl-α-azaornithine phenyl ester, which has trypsin inhibitory activity .

HY-20841

Boc-(2S)-Gly-4-pyranoyl (S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid; Boc-4-Pyranoyl-Gly-OH	Amino Acid Derivatives	Others
Boc-(2S)-Gly-4-pyranoyl ((S)-2-((tert-Butoxycarbonyl)amino)-2-(tetrahydro-2H-pyran-4-yl)acetic acid) is an amino-terminally protected glycine derivative that can be used to synthesize dipeptidyl peptidase IV with antidiabetic activity .

HY-137002

Fmoc-N-Me-Arg(Pbf)-OH	Amino Acid Derivatives	Others
Fmoc-N-Me-Arg(Pbf)-OH is an amino acid derivative containing a guanidinium protecting group on the arginine side chain. Fmoc-N-Me-Arg(Pbf)-OH is used in the synthesis of neurotensin-derived NTS1 ligands for PET imaging .

HY-W048739

Fmoc-α-Me-Leu-OH	Amino Acid Derivatives	Others
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .

HY-46398

Fmoc-Val-Phe-Boc	PROTAC Linkers	Cancer
Fmoc-Val-Phe-Boc is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Val-Phe-Boc can be used in the synthesis of the Deruxtecan .

HY-129077

FR179642	Fungal	Infection
FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin . FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379 .

Cat. No.	Product Name

HY-L033

Peptidomimetic Library

375 compounds

Peptidomimetics are compounds whose essential elements (pharmacophore) mimic a natural peptide or protein in 3D space and which retain the ability to interact with the biological target and produce the same biological effect. Peptidomimetics are designed to circumvent some of the problems associated with a natural peptide: e.g. stability against proteolysis (duration of activity) and poor bioavailability. Certain other properties, such as receptor selectivity or potency, often can be substantially improved. The design and synthesis of peptidomimetics are most important because of the dominant position peptide and protein-protein interactions play in molecular recognition and signaling, especially in living systems. Hence mimics have great potential in drug discovery.

MCE Peptidomimetic Library contains 375 compounds including peptoid, α-helix mimetics, β-turn/sheets mimetics, etc. This library is an indispensable tool of structure-activity relationships in drug discovery.

Cat. No.	Product Name	Type

HY-D0177

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate	Biochemical Assay Reagents
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and can be utilized in solid phase synthesis test .

HY-P5282

ApoA-I mimetic peptide	Drug Delivery
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .

HY-W002327

Fmoc-Asn(Trt)-OH	Biochemical Assay Reagents
Fmoc-Asn(Trt)-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Fmoc-Asn(Trt)-OH can be used for synthesis of Fmoc-based solid-phase peptide synthesis .

HY-D0178

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride

Biochemical Assay Reagents

1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

Cat. No.	Product Name

HY-K1057

Puromycin, Sterile 10+ Cited Publications
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2403

Dihydrolycorine 1 Publications Verification	Alkaloids Lycoris radiata (L’Her.) Herb. other families Pyrrole Alkaloids Neurological Disease Classification of Application Fields Source classification Plants Disease Research Fields Amaryllidaceae	Others
Dihydrolycorine, isolated from Lycoris radiate Herb, is an inhibitor of protein synthesis in eukarytic cells by inhibiting the peptide bone formation step .

HY-129077

FR179642	Infection Monophenols Microorganisms Classification of Application Fields Cyclopeptides Source classification Phenols Disease Research Fields	Fungal
FR179642 is a key intermediate in the synthesis of the echinocandin antifungal Micafungin . FR179642 is the cyclic peptide nucleus of the echinocandin-like antifungal lipopeptide FR901379 .

HY-P2834

Penicillin amidase, E. coli PGA	Classification of Application Fields Disease Research Fields Cancer	Biochemical Assay Reagents
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics .

HY-17566

Capreomycin sulfate 2 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease .

HY-13948

Angiotensin II human Maximum Cited Publications 111 Publications Verification Angiotensin II; Ang II; DRVYIHPF	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology Cancer	Angiotensin Receptor Apoptosis
Angiotensin II (Angiotensin II) is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human also induces apoptosis. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway .

HY-120286

K-13	Structural Classification Natural Products Microorganisms Source classification	Others
K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.

HY-131083

ε-Amanitin	Structural Classification Natural Products Monophenols Microorganisms Classification of Application Fields Source classification Phenols Disease Research Fields Cancer	DNA/RNA Synthesis ADC Cytotoxin
ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II .

HY-N6680

Virginiamycin S1	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections ^[1][2].

HY-17566R

Capreomycin sulfate (Standard)	Structural Classification Microorganisms Antibiotics Source classification Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics	Antibiotic Bacterial
Capreomycin (sulfate) (Standard) is the analytical standard of Capreomycin (sulfate). This product is intended for research and analytical applications. Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease .

HY-N6680R

Virginiamycin S1 (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antibacterial Disease Research	Bacterial Antibiotic
Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections .

Cat. No.	Product Name	Chemical Structure

HY-Y1636S1

L-Arginine-N-FMOC PBF-OH-13C6
L-Arginine-N-FMOC PBF-OH- ¹³C₆ is the ¹³C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].

HY-Y1169S1

Fmoc-Asp(OtBu)-OH-13C4,15N
Fmoc-Asp(OtBu)-OH- ¹³C₄, ¹⁵N is the ¹³C and ¹⁵N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].

HY-W010712S1

Fmoc-His(Trt)-OH-15N3
Fmoc-His(Trt)-OH- ¹⁵N₃ is the ¹⁵N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].

Cat. No.	Product Name		Classification

HY-151783

DAPOA		Azide
DAPOA is a click chemistry reagent containing an azide group. DAPOA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151783A

DAPOA (DCHA)		Azide
DAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151825

Fmoc-L-Phe(4-NH-Poc)-OH		Alkynes
Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry .

HY-151824

Boc-L-Phe(4-NH-Poc)-OH		Alkynes
Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in peptide synthesis. Propargyloxycarbonyl, commonly abbreviated as Poc or Pryoc, can either be used as alkyne component for standard Click conjugation or in combination with tetrazine linkers in copper-free Diels-Alder type Click reactions. It also has applications as unusual protecting group for amines, hydroxy functions and as esters. All 3 are stable to neat TFA, but can be cleaved at ambient temperature with Co2(CO)8 in TFA:DCM. Deprotection with other transition metals like palladium have also been reported . Boc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151738

Fmoc-Aeg(N3)-OH		Azide
Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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Peptide Synthesis

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