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Results for "

fluorescent peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (4) Fluorescent Dye (62) Peptide-Drug Conjugates (PDCs) (1) Angiotensin-converting Enzyme (ACE) (2) Bacterial (2) Beta-secretase (2) Biochemical Assay Reagents (6) Bombesin Receptor (1) Caspase (4) Cathepsin (1) EBV (1) EGFR (1) Integrin (4) Isotope-Labeled Compounds (2) MetAP (1) MMP (5) Neurokinin Receptor (1) PKA (1) Potassium Channel (1) Radionuclide-Drug Conjugates (RDCs) (1) Ser/Thr Protease (1) STAT (2)
By Research Areas:	Cancer (17) Infection (5) Inflammation/Immunology (1) Neurological Disease (10)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Fluorescent Dye Formyl Peptide Receptor (FPR) Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15944

5(6)-TAMRA 2 Publications Verification 5(6)-Carboxytetramethylrhodamine	Fluorescent Dye	Others
5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.

HY-P1188

LDV-FITC	Integrin	Cancer
LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn ²⁺ respectively). LDV-FITC can be used to detect α4β1 integrin affinity .

HY-W039519

7-Methoxycoumarin-3-carboxylic acid	Fluorescent Dye	Cancer
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .

HY-15938

5-FAM SE	Fluorescent Dye	Others
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-135414

Cyanine5 NHS ester chloride	Fluorescent Dye	Others
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-P1188A

LDV-FITC TFA	Integrin	Cancer
LDV-FITC TFA, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC TFA binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn ²⁺ respectively). LDV-FITC TFA can be used to detect α4β1 integrin affinity .

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dye	Others
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-W927376

Boc-Val-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dye	Others
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-P10172

Abz-SDK(Dnp)P-OH	Angiotensin-converting Enzyme (ACE)	Neurological Disease
Abz-SDK(Dnp)P-OH is a fluorescence peptide. Abz-SDK(Dnp)P-OH is the substrate of angiotensin I-converting enzyme (ACE). Abz-SDK(Dnp)P-OH has fluorescent donor-acceptor pair Abz and Dnp (2,4-dinitrophenyl) .

HY-P4425

Gly-Phe-AMC	Biochemical Assay Reagents	Others
Gly-Phe-AFC is a fluorescent substrate, which is a peptide sequence composed of glycine and phenylalanine, linked to the fluorescent group AFC .

HY-P1459

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)	Bacterial	Infection
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.

HY-P4344

Met-Gly-Pro-AMC	MetAP	Others
Met-Gly-Pro-AMC is a fluorescent peptide substrate of MetAP2 .

HY-P2603

Bz-Dab(NBD)-AwFpP-Nle-NH2	Neurokinin Receptor	Neurological Disease
Bz-Dab(NBD)-AwFpP-Nle-NH2 (Compound 5B) is a potent fluorescent antagonist of NK2 receptor, with a pK_i of 8.87 nM (Ex=340 nm, Em=505 nm) .

HY-D2495

Cy7 SE (nosulfo)	Fluorescent Dye	Others
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.

HY-D1849

Cy3B NHS ester	Fluorescent Dye	Others
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-P4364

Suc-Phe-Leu-Phe-4MβNA	Biochemical Assay Reagents	Others
Suc-Phe-Leu-Phe-4MβNA is a fluorescent peptide substrate .

HY-P5287

cRGDfK-thioacetyl ester	Integrin	Cancer
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-D1423

Dibromobimane	Fluorescent Dye	Others
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-137367

Z-Val-Val-Arg-AMC	Cathepsin	Infection
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins .

HY-W879234

TriSulfo-Cy5.5 DBCO Sulfo Cy5.5-DBCO	Fluorescent Dye	Others
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.

HY-P5287A

cRGDfK-thioacetyl ester TFA	Integrin	Cancer
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-137834A

Gly-Pro-AMC	Biochemical Assay Reagents	Others
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-P0248F

Kemptide, 5-FAM labeled	PKA Fluorescent Dye	Others
Kemptide, 5-FAM labeled is a biological active peptide. (Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. 5-FAM labeled HY-P0248)

HY-P5355

Z-Gly-Gly-Arg-AFC	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AFC is a biological active peptide. (Plasminogen Activator Acrosine Substrate, fluorescent Z-Gly-Gly-Arg-AFC)

HY-D0715

Fluorescamine Ro 20-7234	Fluorescent Dye	Others
Fluorescamine (Ro 20-7234) is a spirocyclic compound with no fluorescent properties. It can react with primary amines and form fluorescence, so it is used to detect amines and peptides.

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dye	Others
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .

HY-P10648

Herceptide HER2-targeting peptide	EGFR	Cancer
Herceptide (HER2-targeting peptide) is a HER2-targeting peptide, and can be further conjugated to the near-infrared fluorescent dye indocyanine green (HY-D0711) (ICG) for developing theranostic agents .

HY-P10651

Lifeact peptide	Bacterial	Infection
Lifeact peptide is a fusion structure of BP100 bound to actin. BP100 (KKLFKKILKYL-amide) is an antimicrobial peptide against plant pathogens that acts as a fast and effective cell penetrant to transport fluorescent test cargo into the cytoplasm of plant cell walls .

HY-P5295

Cy3-Ova (323-339)	Fluorescent Dye	Others
Cy3-Ova (323-339) is an Cy3 labled OVA Peptide (323-339) (HY-P0286). Cy3 is a fluorescent dye belonging to the Cyanine family and is a fluorescent light product of Cy5. Cyanine is commonly used in fluorescence microscopy, cell imaging, and molecular biology experiments. OVA Peptide (323-339) represents the T and B cell epitopes of ovalbumin (OVA). OVA Peptide (323-339) has limited immunogenic efficacy in activating OVA-sensitized and attacked mouse spleen cells .

HY-P2550A

β-Amyloid (1-40), FAM-labeled TFA	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).

HY-D2498

Cy7 maleimide	Fluorescent Dye	Others
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .

HY-D2439

RGD-PEG-Cy3	Fluorescent Dye	Cancer
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .

HY-P2550

β-Amyloid (1-40), FAM-labeled	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled?β-Amyloid (1-40) peptide (λ_ex=?492?nm and λ_em=?518?nm) .

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dye	Others
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .

HY-W027544

MCA	Fluorescent Dye	Others
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-P1362FA

Cy5-β-Amyloid (42-1), human Tris Cy5-Amyloid β peptide (42-1)(human) Tris	Amyloid-β	Neurological Disease
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-P1362F

Cy5-β-Amyloid (42-1), human Cy5-Amyloid β peptide (42-1)(human)	Amyloid-β	Neurological Disease
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-D2488

Sulfo Cy5.5-maleimide	Fluorescent Dye	Others
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.

HY-P3722

Mca-PLAQAV-Dpa-RSSSR-NH2	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE; ADAM17), ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-P3722A

Mca-PLAQAV-Dpa-RSSSR-NH2 TFA	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE): ADAM17, ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-66022

5-FAM 3 Publications Verification 5-Carboxyfluorescein	Fluorescent Dye	Others
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .

HY-P10202

5-FAM-GpYLPQTV-NH2	STAT	Cancer
5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .

HY-P5367

5-FAM-PMDM6 PMDM6-F	Fluorescent Dye	Others
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)

HY-P10202A

5-FAM-GpYLPQTV-NH2 TFA	STAT	Cancer
5-FAM-GpYLPQTV-NH2 (TFA) is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 (TFA) can be used in cancer research .

HY-D0715R

Fluorescamine (Standard)	Fluorescent Dye	Others
Fluorescamine (Standard) is the analytical standard of Fluorescamine. This product is intended for research and analytical applications. Fluorescamine (Ro 20-7234) is a spirocyclic compound with no fluorescent properties. It can react with primary amines and form fluorescence, so it is used to detect amines and peptides.

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

Cat. No.	Product Name	Type

HY-15944

5(6)-TAMRA 2 Publications Verification 5(6)-Carboxytetramethylrhodamine	Fluorescent Dyes/Probes
5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.

HY-W039519

7-Methoxycoumarin-3-carboxylic acid	Fluorescent Dyes/Probes
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .

HY-15938

5-FAM SE	Fluorescent Dyes/Probes
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-D1849

Cy3B NHS ester	Fluorescent Dyes/Probes
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-D1423

Dibromobimane	Fluorescent Dyes/Probes
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-135414

Cyanine5 NHS ester chloride	Fluorescent Dyes/Probes
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dyes/Probes
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes/Probes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D2495

Cy7 SE (nosulfo)	Fluorescent Dyes/Probes
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.

HY-W879234

TriSulfo-Cy5.5 DBCO Sulfo Cy5.5-DBCO	Fluorescent Dyes/Probes
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dyes/Probes
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-137834A

Gly-Pro-AMC	Fluorescent Dyes/Probes
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dyes/Probes
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-D0715

Fluorescamine Ro 20-7234	Protein Labeling
Fluorescamine (Ro 20-7234) is a spirocyclic compound with no fluorescent properties. It can react with primary amines and form fluorescence, so it is used to detect amines and peptides.

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dyes/Probes
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .

HY-D2498

Cy7 maleimide	Fluorescent Dyes/Probes
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .

HY-D2439

RGD-PEG-Cy3

Fluorescent Dyes/Probes

RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dyes/Probes
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .

HY-W027544

MCA	Fluorescent Dyes/Probes
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-P1362FA

Cy5-β-Amyloid (42-1), human Tris Cy5-Amyloid β peptide (42-1)(human) Tris	Fluorescent Dyes/Probes
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-P1362F

Cy5-β-Amyloid (42-1), human Cy5-Amyloid β peptide (42-1)(human)	Fluorescent Dyes/Probes
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-D2488

Sulfo Cy5.5-maleimide	Fluorescent Dyes/Probes
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.

HY-66022

5-FAM 3 Publications Verification 5-Carboxyfluorescein	Fluorescent Dyes/Probes
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .

HY-D0715R

Fluorescamine (Standard)	Protein Labeling
Fluorescamine (Standard) is the analytical standard of Fluorescamine. This product is intended for research and analytical applications. Fluorescamine (Ro 20-7234) is a spirocyclic compound with no fluorescent properties. It can react with primary amines and form fluorescence, so it is used to detect amines and peptides.

HY-W024881

2,3,3-trimethyl-3H-Indole-5-sulfonic acid potassium salt (1:1)	Fluorescent Dyes/Probes
2,3,3-Trimethylindolenine-5-sulfonic acid potassium is a water-soluble fluorescent near-infrared dye that can be coupled to peptides, proteins, nucleic acids, RNA, DNA, carbohydrates, polymers, and small molecules via sulfonyl substituents .

HY-D2441

TAT-PEG-Cy3

Fluorescent Dyes/Probes

TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .

HY-D0154

6-TRITC Tetramethylrhodamine-6-isothiocyanate	Fluorescent Dyes/Probes
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .

HY-D1756

ROX NHS ester, 6-isomer	Fluorescent Dyes/Probes
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.

HY-131498

MOCAc-PLGL(Dpa)AR Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

HY-149117

AF430 NHS ester	Fluorescent Dyes/Probes
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .

HY-15940

5(6)-Carboxyfluorescein 3 Publications Verification 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers	Fluorescent Dyes/Probes
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .

HY-137858

H-Gly-Arg-pNA hydrochloride Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride	Dyes
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .

HY-D1596A

Cyanine 3.5 bromide Cy3.5 NHS ester bromide; Cy 3.5 bromide	Fluorescent Dyes/Probes
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D0017

Dansyl chloride DNSCl	Protein Labeling
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-D1800

Vari Fluor 680 SE VF 680 SE	Fluorescent Dyes/Probes
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1801

Vari Fluor 488 SE VF 488 SE	Dyes
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1790

Vari Fluor 640 SE VF 640 SE	Dyes
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1802

Vari Fluor 425 SE VF 425 SE	Dyes
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1803

Vari Fluor 565 SE VF 565 SE	Dyes
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1797

Vari Fluor 660 SE VF 660 SE	Dyes
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1798

Vari Fluor 350 SE VF 350 SE	Dyes
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1799

Vari Fluor 568 SE 1 Publications Verification VF 568 SE	Dyes
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1791

Vari Fluor 750 SE VF 750 SE	Dyes
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1792

Vari Fluor 555 SE VF 555 SE	Dyes
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1794

Vari Fluor 405 SE VF 405 SE	Dyes
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1795

Vari Fluor 532 SE VF 532 SE	Dyes
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1796

Vari Fluor 594 SE VF 594 SE	Dyes
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D2194

AgAuSe-COOH (1000 nm)	Fluorescent Dyes/Probes
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.

HY-66019

FITC

Maximum Cited Publications

49 Publications Verification

Fluorescein 5-isothiocyanate

Fluorescent Dyes/Probes

FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .

HY-D0098

Fluorescein-5-maleimide

3 Publications Verification

N-(5-Fluoresceinyl)maleimide

Fluorescent Dyes/Probes

Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .

Cat. No.	Product Name	Type

HY-Y0623

N-Hydroxysuccinimide HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .

Cat. No.	Product Name	Target	Research Area

HY-P1188

LDV-FITC	Integrin	Cancer
LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn ²⁺ respectively). LDV-FITC can be used to detect α4β1 integrin affinity .

HY-P4931

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-P10172

Abz-SDK(Dnp)P-OH	Angiotensin-converting Enzyme (ACE)	Neurological Disease
Abz-SDK(Dnp)P-OH is a fluorescence peptide. Abz-SDK(Dnp)P-OH is the substrate of angiotensin I-converting enzyme (ACE). Abz-SDK(Dnp)P-OH has fluorescent donor-acceptor pair Abz and Dnp (2,4-dinitrophenyl) .

HY-P4343

Lys(Abz)-Pro-Pro-pNA	Peptides	Others
Lys(Abz)-Pro-Pro-pNA is a fluorescent peptide substrate of PepP .

HY-P4344

Met-Gly-Pro-AMC	MetAP	Others
Met-Gly-Pro-AMC is a fluorescent peptide substrate of MetAP2 .

HY-P1188A

LDV-FITC TFA	Integrin	Cancer
LDV-FITC TFA, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC TFA binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn ²⁺ respectively). LDV-FITC TFA can be used to detect α4β1 integrin affinity .

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dye	Others
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-P4425

Gly-Phe-AMC	Biochemical Assay Reagents	Others
Gly-Phe-AFC is a fluorescent substrate, which is a peptide sequence composed of glycine and phenylalanine, linked to the fluorescent group AFC .

HY-P1459

Sphistin Synthetic Peptide(12-38,Fitc in N-Terminal-Fluorescently Labeled Peptide)	Bacterial	Infection
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.

HY-P2603

Bz-Dab(NBD)-AwFpP-Nle-NH2	Neurokinin Receptor	Neurological Disease
Bz-Dab(NBD)-AwFpP-Nle-NH2 (Compound 5B) is a potent fluorescent antagonist of NK2 receptor, with a pK_i of 8.87 nM (Ex=340 nm, Em=505 nm) .

HY-P4364

Suc-Phe-Leu-Phe-4MβNA	Biochemical Assay Reagents	Others
Suc-Phe-Leu-Phe-4MβNA is a fluorescent peptide substrate .

HY-P5287

cRGDfK-thioacetyl ester	Integrin	Cancer
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-W009686F

5-FAM-Pro-Leu-OH	Peptides	Others
5-FAM-Pro-Leu-OH is a biological active peptide. (Used as MMP fluorescent reference standard)

HY-137367

Z-Val-Val-Arg-AMC	Cathepsin	Infection
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins .

HY-W436471

H-Ala-Pro-AFC	Peptides	Others
H-Ala-Pro-AFC is a biological active peptide. (This is a fluorescent peptide, Abs/Em=380/500nm. It is a substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase.)

HY-P5287A

cRGDfK-thioacetyl ester TFA	Integrin	Cancer
cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-137834A

Gly-Pro-AMC	Biochemical Assay Reagents	Others
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-P0248F

Kemptide, 5-FAM labeled	PKA Fluorescent Dye	Others
Kemptide, 5-FAM labeled is a biological active peptide. (Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. 5-FAM labeled HY-P0248)

HY-P5355

Z-Gly-Gly-Arg-AFC	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AFC is a biological active peptide. (Plasminogen Activator Acrosine Substrate, fluorescent Z-Gly-Gly-Arg-AFC)

HY-P10648

Herceptide HER2-targeting peptide	EGFR	Cancer
Herceptide (HER2-targeting peptide) is a HER2-targeting peptide, and can be further conjugated to the near-infrared fluorescent dye indocyanine green (HY-D0711) (ICG) for developing theranostic agents .

HY-P10651

Lifeact peptide	Bacterial	Infection
Lifeact peptide is a fusion structure of BP100 bound to actin. BP100 (KKLFKKILKYL-amide) is an antimicrobial peptide against plant pathogens that acts as a fast and effective cell penetrant to transport fluorescent test cargo into the cytoplasm of plant cell walls .

HY-P5295

Cy3-Ova (323-339)	Fluorescent Dye	Others
Cy3-Ova (323-339) is an Cy3 labled OVA Peptide (323-339) (HY-P0286). Cy3 is a fluorescent dye belonging to the Cyanine family and is a fluorescent light product of Cy5. Cyanine is commonly used in fluorescence microscopy, cell imaging, and molecular biology experiments. OVA Peptide (323-339) represents the T and B cell epitopes of ovalbumin (OVA). OVA Peptide (323-339) has limited immunogenic efficacy in activating OVA-sensitized and attacked mouse spleen cells .

HY-P2550A

β-Amyloid (1-40), FAM-labeled TFA	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).

HY-P2550

β-Amyloid (1-40), FAM-labeled	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled?β-Amyloid (1-40) peptide (λ_ex=?492?nm and λ_em=?518?nm) .

HY-P3722

Mca-PLAQAV-Dpa-RSSSR-NH2	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE; ADAM17), ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-P3722A

Mca-PLAQAV-Dpa-RSSSR-NH2 TFA	Fluorescent Dye MMP	Others
Mca-PLAQAV-Dpa-RSSSR-NH2 is a fluorescent peptide and as one of fluorescent substrates of TNF-α converting enzyme (TACE): ADAM17, ADAM 9 and ADAM 10. Mca-PLAQAV-Dpa-RSSSR-NH2 is a substrate based on fluorescence resonance energy transfer, and its activity can be determined by the change of fluorescence intensity during pyrolysis .

HY-P10202

5-FAM-GpYLPQTV-NH2	STAT	Cancer
5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .

HY-P5367

5-FAM-PMDM6 PMDM6-F	Fluorescent Dye	Others
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)

HY-P10202A

5-FAM-GpYLPQTV-NH2 TFA	STAT	Cancer
5-FAM-GpYLPQTV-NH2 (TFA) is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 (TFA) can be used in cancer research .

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P5908F

FAM-DEALA-Hyp-YIPD	Peptides	Others
FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide, with the K_d of 180-560 nM. FAM-DEALA-Hyp-YIPD can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity .

HY-P5378

Ac-KQKLR-AMC Cathepsin S substrate	Ser/Thr Protease	Others
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)

HY-P10772

L2P4	Peptide-Drug Conjugates (PDCs) EBV	Cancer
L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC₅₀ of 46.4 μM .

HY-P5481

DABCYL-LPETG-EDANS	Peptides	Others
DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

HY-P4899

RE(EDANS)EVNLDAEFK(DABCYL)R	Beta-secretase	Neurological Disease
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .

HY-P5356

H-D-Val-Leu-Lys-AFC Plasmin substrate	Fluorescent Dye	Others
H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a biological active peptide. (This is a fluorescent plasmin substrate, Abs/Em=380/500 nm.Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.)

HY-P1883

Bacterial Sortase Substrate III, Abz/DNP	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P1883A

Bacterial Sortase Substrate III, Abz/DNP TFA	Fluorescent Dye	Infection
Bacterial Sortase Substrate III, Abz/DNP TFA is an internally quenched fluorescent peptide substrate. Staphylococcus aureus transpeptidase sortase A (SrtA) reacts with its native substrate Bacterial Sortase Substrate III, Abz/DNP, cleaving it and catalyzing the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Cleavage of this substrate can be monitored at Ex/Em=320 nm/420 nm.

HY-P4919

Mca-SEVNLDAEFK(Dnp)	Beta-secretase	Others
Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.

HY-P5520

GB-6	Bombesin Receptor Radionuclide-Drug Conjugates (RDCs)	Cancer
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .

HY-P4742A

6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) (TFA) 6-FAM-AEEAC-SHK TFA	Biochemical Assay Reagents Potassium Channel	Neurological Disease
6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) TFA (6-FAM-AEEAC-SHK TFA) is a peptide neurotoxin conjugated with a fluorescent marker. 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) TFA can block voltage-gated potassium channels (kv1.1 and kv1.2) to prolong the duration of action potentials, thereby affecting the conduction of neural signals. 6-FAM-AEEAc-Stichodactyla helianthus Neurotoxin (ShK) TFA can be used in neuroscience research .

HY-P10147

Ac-LDESD-AMC	Caspase	Cancer
Ac-LDESD-AMC is a caspase-2 inhibitor. Ac-LDESD-AMC has a peptide sequence of Leu-Asp-Glu-Ser-Asp .

HY-P10162

Ac-DMQD-AMC	Caspase	Cancer
Ac-DMQD-AMC is an inhibitor of caspase-3. Ac-DMQD-AMC is an aromatic amine using aminium-based coupling reagent HATU in the presence of 2,4,6-trimethylpyridine (TMP) .

HY-P10173

Abz-LFK(Dnp)-OH	Angiotensin-converting Enzyme (ACE)	Others
Abz-LFK(Dnp)-OH is an angiotensin I-converting enzyme (ACE) peptide substrate. Abz-LFK(Dnp)-OH is selective for the C domain of ACE. Abz-LFK(Dnp)-OH can be used to assess ACE activity .

HY-P10196

DABCYL-SEVNLDAEF-EDANS	Peptides	Others
DABCYL-SEVNLDAEF-EDANS is a substrate of FRET. DABCYL-SEVNLDAEF-EDANS can be used in the BACE activity assay .

HY-P10197

DABCYL-VNLDAE-EDANS	Peptides	Others
DABCYL-VNLDAE-EDANS is a substrate of b-secretase. DABCYL-VNLDAE-EDANS can be used in BACE enzyme assays .

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-P10144

Ac-Orn-Phe-Arg-AMC	Fluorescent Dye	Others
Ac-Orn-Phe-Arg-AMC is a potent fluorescent substrate of cd–Tryptase and β 1-Tryptase. Ac-Orn-Phe-Arg-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection .

HY-P10189

α-Secretase Substrate, Fluorogenic	Biochemical Assay Reagents	Others
α-Secretase Substrate, Fluorogenic is α-secretase fluorogenic substrate that can be used to test α-secretase activity .

HY-P10142

Ac-YEVD-AMC	Fluorescent Dye	Others
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .

Cat. No.	Product Name	Chemical Structure

HY-W027544S

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d3
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₃ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide		Alkynes
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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