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Results for "

pentacyclic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) AMPK (1) Androgen Receptor (2) Antibiotic (3) Apoptosis (15) Autophagy (7) Bacterial (5) Bcl-2 Family (1) Biochemical Assay Reagents (2) Calcium Channel (1) Caspase (2) COX (1) Drug Derivative (2) Endogenous Metabolite (8) ERK (2) Fatty Acid Synthase (FASN) (1) Fungal (2) Glycosidase (1) GSK-3 (2) HIV (2) Interleukin Related (3) JAK (1) Keap1-Nrf2 (2) Leukotriene Receptor (2) Lipoxygenase (2) LXR (2) Mitophagy (2) NF-κB (6) NO Synthase (4) p38 MAPK (2) Parasite (5) PI3K (1) PPAR (1) Pyroptosis (1) Reactive Oxygen Species (3) Ser/Thr Protease (1) SOD (1) Somatostatin Receptor (1) STAT (1) TNF Receptor (2) Topoisomerase (2)
By Research Areas:	Cancer (29) Cardiovascular Disease (3) Endocrinology (2) Infection (10) Inflammation/Immunology (26) Metabolic Disease (6) Neurological Disease (10)

By Targets:

Akt (1)

AMPK (1)

Androgen Receptor (2)

Antibiotic (3)

Apoptosis (15)

Autophagy (7)

Bacterial (5)

Bcl-2 Family (1)

Biochemical Assay Reagents (2)

Calcium Channel (1)

Caspase (2)

COX (1)

Drug Derivative (2)

Endogenous Metabolite (8)

ERK (2)

Fatty Acid Synthase (FASN) (1)

Fungal (2)

Glycosidase (1)

GSK-3 (2)

HIV (2)

Interleukin Related (3)

JAK (1)

Keap1-Nrf2 (2)

Leukotriene Receptor (2)

Lipoxygenase (2)

LXR (2)

Mitophagy (2)

NF-κB (6)

NO Synthase (4)

p38 MAPK (2)

Parasite (5)

PI3K (1)

PPAR (1)

Pyroptosis (1)

Reactive Oxygen Species (3)

Ser/Thr Protease (1)

SOD (1)

Somatostatin Receptor (1)

STAT (1)

TNF Receptor (2)

Topoisomerase (2)

By Research Areas:

Cancer (29)

Cardiovascular Disease (3)

Endocrinology (2)

Infection (10)

Inflammation/Immunology (26)

Metabolic Disease (6)

Neurological Disease (10)

Inhibitors & Agonists

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8879

Wilforol A (-)-Wilforol A	Others	Metabolic Disease
Wilforol A ((-)-Wilforol A), plant metabolite, is a pentacyclic triterpenoid. Wilforol A can be used for the research of various biochemical studies .

HY-N6255

Ilexgenin A	TNF Receptor	Inflammation/Immunology Cancer
Ilexgenin A is a pentacyclic triterpenoid, which extracted from Ilex hainanensis Merr. Ilexgenin A can be used for the research of inflammation and cancer .

HY-N6601

Pomolic acid Randialic acid A	Apoptosis	Cancer
Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from?Euscaphis japonica?(Tunb.). Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC) .

HY-N8423

α-Amyrin 1 Publications Verification	ERK GSK-3	Neurological Disease Metabolic Disease
α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can be used in the study of metabolic syndrome induced by high fructose diet and cognitive dysfunction caused by low cholinergic neurotransmission .

HY-N3565

Cephalocyclidin A	Others	Others
Cephalocyclidin A is a pentacyclic alkaloid and can be isolated from Cephalotaxus harringtonia var.nana .

HY-145869

Anti-inflammatory agent 12	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 12 (Compound 2) is a pentacyclic triterpene compound. Anti-inflammatory agent 12 shows a significant bias in the LPS-induced inflammatory response with an IIC₅₀ value of 2.22 μM. Anti-inflammatory agent 12 has the potential for the research of inflammation disease .

HY-128470

Mitoquidone GR-30921	Drug Derivative	Cancer
Mitoquidone (GR-30921) is is the first member of a group of pentacyclic pyrroloquinones. Mitoquidone shows good activity in a range of experimental solid tumour models. Mitoquidone can be used for the research of anti-cancer .

HY-128366

Waltonitone	Apoptosis	Cancer
Waltonitone is a ursane-type pentacyclic triterpene isolated from Gentian waltonii Burkill. Waltonitone significantly inhibits hepatocellular carcinoma cells growth and induces apoptosis in vitro and in vivo .

HY-145870

Anti-inflammatory agent 13	NO Synthase	Inflammation/Immunology
Anti-inflammatory agent 13 (Compound 3) is a pentacyclic triterpene compound. Anti-inflammatory agent 13 exhibits a considerable inhibitory effect on inflammation models. Anti-inflammatory agent 13 has the potential for the research of either DAMPs or PAMPs triggered inflammation .

HY-N8423R

α-Amyrin (Standard)	ERK GSK-3	Neurological Disease Metabolic Disease
α-Amyrin (Standard) is the analytical standard of α-Amyrin. This product is intended for research and analytical applications. α-Amyrin is a pentacyclic triterpenoid compound with oral activity. α-Amyrin activates the ERK and GSK-3β signaling pathways. α-Amyrin can be used in the study of metabolic syndrome induced by high fructose diet and cognitive dysfunction caused by low cholinergic neurotransmission .

HY-N7652

Terminolic acid	Bacterial	Infection Inflammation/Immunology
Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum. Terminolic acid can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. Terminolic acid also exhibits moderate antibacterial activity .

HY-N8781

Tetrahymanol	Others	Others
Tetrahymanol is a pentacyclic triterpenoid that can be found in Tetrahymena pyriformis .

HY-125344

Fusarisetin A	Endogenous Metabolite	Infection
Fusarisetin A, a pentacyclic fungal metabolite, is an acinar morphogenesis inhibitor .

HY-N4165

Arnidiol	Others	Others
Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .

HY-N6983

Licoricesaponin G2	Others	Cancer
Licoricesaponin G2 is a pentacyclic triterpenoid isolated from Glycyrrhiza aspera .

HY-N12876

(18α)-Oleanolic acid (18α)-Oleanic acid; (18α)-Caryophyllin	Others	Cancer
18α-Oleanolic acid is a natural pentacyclic triterpenic acid that can be isolated from plants .

HY-N0271

Echinocystic acid 2 Publications Verification	Reactive Oxygen Species Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Echinocystic acid is a natural pentacyclic triterpene with potent antioxidant, anti-inflammatory and analgesic activities .

HY-N12190

Centellasaponin A	Others	Others
Centellasaponin A (compound 10) is a pentacyclic triterpene saponin isolated from the methanolic extract of Centella asiatica .

HY-N10449

Resistomycin	Antibiotic Apoptosis Bacterial	Cancer
Resistomycin, a pentacyclic polyketide antibiotic, possesses anticancer activity and induces apoptosis .

HY-169040

28-Aminobetulin	Fatty Acid Synthase (FASN)	Metabolic Disease
28-Aminobetulin is a pentacyclic triterpenoid and a derivative of the cholesterol biosynthesis inhibitor Betulin (HY-N0083).

HY-N0140

Ursolic acid 10+ Cited Publications Prunol; Urson; Malol	Autophagy Endogenous Metabolite	Cancer
Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

HY-N1037

δ-Amyrenone Delta-Amyrone	Others	Inflammation/Immunology
δ-Amyrenone (Delta-Amyrone) is a pentacyclic triterpene compound from S. lineare, with anti-inflammatory effects .

HY-N1827

3-epi-Maslinic acid	Others	Others
3-epi-Maslinic acid is an acidic pentacyclic triterpene isolated from Hexane and dichloromethane extracts of Platostoma africanum P. Beauv .

HY-N6946

Mitraphylline	NF-κB	Inflammation/Immunology
Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils .

HY-N3227

Myricadiol	Others	Cancer
Myricadiol, a pentacyclic triterpenoid compound, is a potential lead compound for anticancer agent. Myricadiol can be isolated from Scaevola spinescens R. Br. (Goodeniaceae) .

HY-P3193A

Cyclic nona-L-arginine hydrochloride	Biochemical Assay Reagents	Others
Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .

HY-138992

2,3-Indolobetulin	Glycosidase Endogenous Metabolite	Others
2,3-Indolobetulin is a pentacyclic triterpene and a derivative of betulin. 2,3-Indolobetulin can be used in the synthesis of α-glucosidase inhibitors .

HY-N0271R

Echinocystic acid (Standard)	Reactive Oxygen Species Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Echinocystic acid (Standard) is the analytical standard of Echinocystic acid. This product is intended for research and analytical applications. Echinocystic acid is a natural pentacyclic triterpene with potent antioxidant, anti-inflammatory and analgesic activities .

HY-N3866

Esculentic acid	COX	Inflammation/Immunology
Esculentic acid is a selective COX-2 inhibitor and has anti-inflammatory effect. Esculentic acid is a pentacyclic triterpenoid that can be extracted from the Chinese herb Phytolacca esculenta .

HY-P10672

SEI144	Biochemical Assay Reagents	Others
SEI144 is a low nanomolar binder of USP15 and does not inhibit USP15 activity .

HY-119784

Eupenifeldin	Fungal	Cancer
Eupenifeldin is pentacyclic bistropolone isolated from cultures of Eupenicillium brefeldianum ATCC 74184. Eupenifeldin is cytotoxic against the HCT-116 cell line. Eupenifeldin has the potential for the research of leukemia .

HY-N0140R

Ursolic acid (Standard)	Autophagy Endogenous Metabolite	Cancer
Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy.

HY-N0568

Madecassoside Asiaticoside A	Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase	Cardiovascular Disease Others Neurological Disease Inflammation/Immunology Endocrinology Cancer
Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB ^[5][6], exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity . Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.

HY-169479

Betulinic glycine amide	Drug Derivative	Infection Cancer
Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity .

HY-N1178

Taraxasterol 2 Publications Verification	Interleukin Related LXR	Inflammation/Immunology
Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases .

HY-10529

Betulinic acid Maximum Cited Publications 26 Publications Verification Lupatic acid; Betulic acid	Apoptosis Topoisomerase HIV Autophagy Mitophagy NF-κB Endogenous Metabolite Parasite	Infection Inflammation/Immunology Cancer
Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC₅₀ of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties .

HY-N1508

Ecliptasaponin A	Others	Inflammation/Immunology
Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .

HY-N6946R

Mitraphylline (Standard)	NF-κB	Inflammation/Immunology
Mitraphylline (Standard) is the analytical standard of Mitraphylline. This product is intended for research and analytical applications. Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils .

HY-N13031

Bellericagenin A	Bacterial	Infection
Bellericagenin A is a pentacyclic triterpenic acid isolated from the bark of Terminalia bellerica. Bellericagenin A exhibits antimicrobial activity. Bellericagenin A exhibits a high affinity to alcohol dehydrogenase (ADH), which has the potential for ameliorating the alcoholic liver injury .

HY-N12225

Isoasiaticoside	Others	Neurological Disease
Isoasiaticoside is a pentacyclic triterpene saponin that can be isolated from Centella asiatica. Isoasiaticoside has potential neuroprotective effects in the 6-OHDA (HY-B1081)-induced PC12 cell model .

HY-N0568R

Madecassoside (Standard)	Endogenous Metabolite Apoptosis Autophagy Keap1-Nrf2 p38 MAPK Caspase	Cardiovascular Disease Others Neurological Disease Inflammation/Immunology Endocrinology Cancer
Madecassoside (Standard) is the analytical standard of Madecassoside. This product is intended for research and analytical applications. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity[10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases.

HY-N0611

alpha-Boswellic acid α-Boswellic acid	Others	Neurological Disease Inflammation/Immunology Cancer
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-P10033

SFTI-1	Ser/Thr Protease	Others
SFTI-1 is a cyclic peptide trypsin inhibitor comprising 14 amino acid residues. SFTI-1 is a potent Bowman-Birk inhibitor.

HY-10529R

Betulinic acid (Standard)	Apoptosis Topoisomerase HIV Autophagy Mitophagy NF-κB Endogenous Metabolite Parasite	Infection Inflammation/Immunology Cancer
Betulinic acid (Standard) is the analytical standard of Betulinic acid. This product is intended for research and analytical applications. Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties .

HY-N1178R

Taraxasterol (Standard)	Others Interleukin Related LXR	Inflammation/Immunology
Taraxasterol (Standard) is the analytical standard of Taraxasterol. This product is intended for research and analytical applications. Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases .

HY-N1508R

Ecliptasaponin A (Standard)	Others	Inflammation/Immunology
Ecliptasaponin A (Standard) is the analytical standard of Ecliptasaponin A. This product is intended for research and analytical applications. Ecliptasaponin A , a pentacyclic triterpenoid saponin, is one of major compounds separated from Eclipta prostrate . Eclipta prostrate is considered as a nourishing herbal medicine with pleiotropic effects, including anti-inflammatory, hepatoprotective, antioxidant, and immunomodulatory .

HY-N0790

Lupeol 3 Publications Verification Clerodol; Monogynol B; Fagarasterol	Androgen Receptor Apoptosis	Cancer
Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) .

HY-N12195

Cytochalasin R	Fungal	Infection
Cytochalasin R (compound 17) is a cytochalasin analogue that can be isolated from the endophytic fungus Phomopsis sp. xz-18. Cytochalasin R shows potential antifungal activity .

HY-N0611R

alpha-Boswellic acid (Standard)	Others	Neurological Disease Inflammation/Immunology Cancer
alpha-Boswellic acid (Standard) is the analytical standard of alpha-Boswellic acid. This product is intended for research and analytical applications. alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-N0790R

Lupeol (Standard)	Androgen Receptor Apoptosis	Cancer
Lupeol (Standard) is the analytical standard of Lupeol. This product is intended for research and analytical applications. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) .

Cat. No.	Product Name	Target	Research Area

HY-P3193A

Cyclic nona-L-arginine hydrochloride	Biochemical Assay Reagents	Others
Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .

HY-P4102

Cyclic PSAP peptide	Peptides	Cancer
Cyclic PSAP peptide is a cyclic pentapeptide (DWLPK). Cyclic PSAP peptide exhibits agent-like properties and could inhibit metastatic spread and restrain tumor development in general in vivo .

HY-P10033

SFTI-1	Ser/Thr Protease	Others
SFTI-1 is a cyclic peptide trypsin inhibitor comprising 14 amino acid residues. SFTI-1 is a potent Bowman-Birk inhibitor.

HY-P10027A

Clovibactin TFA	Antibiotic Bacterial	Infection
Clovibactin TFA is the TFA salt form of Clovibactin (HY-P10027). Clovibactin TFA is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .

HY-P1206

CH 275	Somatostatin Receptor	Neurological Disease
CH 275 is a peptide analog of somatostatin and binds preferably to somatostatin receptor 1 (sst₁) with a K_i of 52 nM . CH 275 acts as a potent and selective sst₁ agonist (IC₅₀=30.9 nM) and also displays IC₅₀ values of 345 nM, >1 μM, >10 μM, >10 μM for human sst₃, sst₄, sst₂ and sst₅, respectively . CH 275 can be used for the research of alzheimer’s disease .

HY-P3193

Cyclic nona-L-arginine TFA	Peptides	Others
Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts .

HY-P10672

SEI144	Biochemical Assay Reagents	Others
SEI144 is a low nanomolar binder of USP15 and does not inhibit USP15 activity .

HY-P10027

Clovibactin	Antibiotic Bacterial	Infection
Clovibactin is an antibiotic for drug-resistant bacterial pathogens without detectable resistance. Clovibactin TFA inihibits cell wall synthesis by targeting pyrophosphate of peptidoglycan precursors .

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