6-Benzoylheteratisine

Cat. No.: HY-N9404 Purity: 99.66%: FAQs
Data Sheet SDS COA Handling Instructions

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6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na⁺]i, [Ca²⁺]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge.

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6-Benzoylheteratisine Chemical Structure

CAS No. : 99759-48-5

Size	Price	Stock	Quantity
1 mg	USD 348	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 870	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1350	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description	6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na⁺]i, [Ca²⁺]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge^[1]^[2].
Molecular Weight	495.61
Formula	C₂₉H₃₇NO₆
CAS No.	99759-48-5
Appearance	Solid
SMILES	CO[C@@H]1[C@]23[C@]4([H])[C@@H]([C@@]([C@@]5([C@]6([H])[C@@]3([H])C[C@H](CC5)OC6=O)O)([H])[C@@]2([H])N(C[C@@]4(CC1)C)CC)OC(C7=CC=CC=C7)=O
Structure Classification	Alkaloids Piperidine Alkaloids
Initial Source	Plants Ranunculaceae Aconitum carmichaeli Debx.
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation	Purity: 99.66% Select Batch: Data Sheet (281 KB) SDS (251 KB) COA (270 KB) HNMR (108 KB) CNMR (125 KB) RP-HPLC (265 KB) Handling Instructions (2659 KB)
References	[1]. Gutser UT, et al. The alkaloid 6-benzoylheteratisine inhibits voltage-gated Na+ channels in rat brain synaptosomes. Neuropharmacology. 1998 Sep;37(9):1139-46. [Content Brief] [2]. Ameri A. Effects of the alkaloids 6-benzoylheteratisine and heteratisine on neuronal activity in rat hippocampal slices. Neuropharmacology. 1997 Aug;36(8):1039-46. [Content Brief]