2. Immunology/Inflammation
  3. COX
  4. CP-74006

CP-74006 (compound11h) is a selective Cyclooxygenase-1 inhibitor.

For research use only. We do not sell to patients.

CP-74006 Chemical Structure

CP-74006 Chemical Structure

CAS No. : 4943-86-6

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10 mM * 1 mL in DMSO
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CP-74006 Related Antibodies

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Description

CP-74006 (compound11h) is a selective Cyclooxygenase-1 inhibitor[1].

Molecular Weight

246.69

Formula

C13H11ClN2O
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

NC1=C(C=CC=C1)C(NC2=CC=C(C=C2)Cl)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (709.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0537 mL 20.2684 mL 40.5367 mL
5 mM 0.8107 mL 4.0537 mL 8.1073 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.86%

COA (248 KB) HNMR (241 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0537 mL 20.2684 mL 40.5367 mL 101.3418 mL
5 mM 0.8107 mL 4.0537 mL 8.1073 mL 20.2684 mL
10 mM 0.4054 mL 2.0268 mL 4.0537 mL 10.1342 mL
15 mM 0.2702 mL 1.3512 mL 2.7024 mL 6.7561 mL
20 mM 0.2027 mL 1.0134 mL 2.0268 mL 5.0671 mL
25 mM 0.1621 mL 0.8107 mL 1.6215 mL 4.0537 mL
30 mM 0.1351 mL 0.6756 mL 1.3512 mL 3.3781 mL
40 mM 0.1013 mL 0.5067 mL 1.0134 mL 2.5335 mL
50 mM 0.0811 mL 0.4054 mL 0.8107 mL 2.0268 mL
60 mM 0.0676 mL 0.3378 mL 0.6756 mL 1.6890 mL
80 mM 0.0507 mL 0.2534 mL 0.5067 mL 1.2668 mL
100 mM 0.0405 mL 0.2027 mL 0.4054 mL 1.0134 mL
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CP-74006 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CP-740064943-86-6CP74006CP 74006COXCyclooxygenaseCyclooxygenase-1analgesicsInhibitorinhibitorinhibit

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