2. Gene
  3. ZBTB16 - zinc finger and BTB domain containing 16 Gene

ZBTB16 - zinc finger and BTB domain containing 16 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PLZF; ZNF145

Gene ID: 7704 | Gene type: protein coding

About ZBTB16

Cytogenetic location: 11q23.2 Genomic coordinates (GRCh38): 11:114,059,711-114,256,770 (from NCBI)

This gene has 20 transcripts (splice variants), 273 orthologues, 36 paralogues and is associated with 75 phenotypes. Broad expression in fat (RPKM 27.9), ovary (RPKM 22.2) and 19 other tissues.

Summary

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

ZBTB16 Products(5)

mRNA Protein Name
NM_001018011.3 NP_001018011.1 zinc finger and BTB domain-containing protein 16 isoform 1
NM_001354750.2 NP_001341679.1 zinc finger and BTB domain-containing protein 16 isoform 1
NM_001354751.2 NP_001341680.1 zinc finger and BTB domain-containing protein 16 isoform 1
NM_001354752.1 NP_001341681.1 zinc finger and BTB domain-containing protein 16 isoform 2
NM_006006.6 NP_005997.2 zinc finger and BTB domain-containing protein 16 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
12802276 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12802276 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10688654 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
9294197 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9294197 GOA
enables protein homodimerization activity IDA
IDA: Inferred from direct assay
8622986 GOA
enables transcription corepressor binding IPI
IPI: Inferred from physical interaction
10688654 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cartilage development IDA
IDA: Inferred from direct assay
21547890 GOA
involved in hemopoiesis IDA
IDA: Inferred from direct assay
8541544 GOA
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12802276 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
24359566 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10688654 GOA
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
21547890 GOA
involved in positive regulation of cartilage development IDA
IDA: Inferred from direct assay
21547890 GOA
involved in positive regulation of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
21547890 GOA
involved in positive regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
21547890 GOA
involved in positive regulation of ossification IDA
IDA: Inferred from direct assay
21547890 GOA
Cellular Component GO Annotation Evidence Reference Source
located in PML body IDA
IDA: Inferred from direct assay
9294197 GOA
located in nuclear body IDA
IDA: Inferred from direct assay
19648967 GOA
located in nuclear speck IDA
IDA: Inferred from direct assay
8541544 GOA
located in nucleus IDA
IDA: Inferred from direct assay
9294197 GOA
part of protein-containing complex IMP
IMP: Inferred from mutant phenotype
10980608 GOA
part of transcription repressor complex IDA
IDA: Inferred from direct assay
12802276 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB16 Protein Structure

BTB

BTB: BTB/POZ domain (25 - 124)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (434 - 454)

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (461 - 483)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (492 - 512)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (532 - 555)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (561 - 584)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (589 - 610)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (630 - 652)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 16

promyelocytic leukaemia zinc finger

ZBTB16 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
26871637
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Validated Y2H
26871637
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Validated Y2H
32296183
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Y2H Array
26871637
Intra
ZBTB16 Q05516 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
ZBTB16 Q05516 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
ZBTB16 Q05516 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
ZBTB16 Q05516 CCHCR1 Homo sapiens Q8TD31-3
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 CCHCR1 Homo sapiens Q8TD31-3
Validated Y2H
32296183
Intra
ZBTB16 Q05516 CCHCR1 Homo sapiens Q8TD31-3
Y2H Array
32296183
Intra
ZBTB16 Q05516 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
ZBTB16 Q05516 UBE2I Homo sapiens Q7KZS0
Validated Y2H
32296183
Intra
ZBTB16 Q05516 NFKBID Homo sapiens Q8NI38
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 NFKBID Homo sapiens Q8NI38
Validated Y2H
32296183
Intra
ZBTB16 Q05516 NFKBID Homo sapiens Q8NI38
Y2H Array
32296183
Intra
ZBTB16 Q05516 SH2D4A Homo sapiens Q9H788-2
Y2H Prey Pooling
25416956
Intra
ZBTB16 Q05516 OSBPL3 Homo sapiens Q9H4L5
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 OSBPL3 Homo sapiens Q9H4L5
Validated Y2H
32296183
Intra
ZBTB16 Q05516 OSBPL3 Homo sapiens Q9H4L5
Y2H Array
32296183
Intra
ZBTB16 Q05516 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
ZBTB16 Q05516 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra
ZBTB16 Q05516 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZBTB16 Q05516 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 CARD9 Homo sapiens Q9H257-2
Validated Y2H
32296183
Intra
ZBTB16 Q05516 CARD9 Homo sapiens Q9H257-2
Y2H Array
32296183
Intra
ZBTB16 Q05516 CARD9 Homo sapiens Q9H257-2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
ZBTB16 Q05516 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra
ZBTB16 Q05516 RAB3IP Homo sapiens Q96QF0-7
Validated Y2H
32296183
Intra
ZBTB16 Q05516 RAB3IP Homo sapiens Q96QF0-7
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 RAB3IP Homo sapiens Q96QF0-7
Y2H Array
32296183
Intra
ZBTB16 Q05516 ZBTB42 Homo sapiens B2RXF5
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 ZBTB42 Homo sapiens B2RXF5
Y2H Array
32296183
Intra
ZBTB16 Q05516 PIBF1 Homo sapiens Q4G0R1
Validated Y2H
32296183
Intra
ZBTB16 Q05516 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
ZBTB16 Q05516 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
ZBTB16 Q05516 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
ZBTB16 Q05516 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
ZBTB16 Q05516 FAM217B Homo sapiens Q9NTX9
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 FAM217B Homo sapiens Q9NTX9
Validated Y2H
32296183
Intra
ZBTB16 Q05516 FAM217B Homo sapiens Q9NTX9
Y2H Array
32296183
Intra
ZBTB16 Q05516 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
25416956
Intra
ZBTB16 Q05516 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
ZBTB16 Q05516 TRIM54 Homo sapiens Q9BYV2
Y2H Array
25416956
Intra
ZBTB16 Q05516 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
ZBTB16 Q05516 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 EFHC2 Homo sapiens Q5JST6
Validated Y2H
32296183
Intra
ZBTB16 Q05516 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra
ZBTB16 Q05516 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
32296183
Intra
ZBTB16 Q05516 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
ZBTB16 Q05516 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 ZNF552 Homo sapiens Q9H707
Validated Y2H
32296183
Intra
ZBTB16 Q05516 ZNF552 Homo sapiens Q9H707
Y2H Array
32296183
Intra
ZBTB16 Q05516 ZNF552 Homo sapiens Q9H707
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
Intra
ZBTB16 Q05516 PML Homo sapiens P29590
Pull Down
9294197
Intra
ZBTB16 Q05516 PML Homo sapiens P29590
Anti Tag CoIP
9294197
Intra
ZBTB16 Q05516 HDAC1 Homo sapiens Q13547
Lumier
37398436
Intra
ZBTB16 Q05516 PML Homo sapiens P29590-5
Y2H
9294197
Intra
ZBTB16 Q05516 PML Homo sapiens P29590-5
Pull Down
9294197
Intra
ZBTB16 Q05516 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra
ZBTB16 Q05516 EEF1A1 Homo sapiens P68104
Y2H
16828757
Intra
ZBTB16 Q05516 EEF1A1 Homo sapiens P68104
Pull Down
16828757
Intra
ZBTB16 Q05516 EEF1A1 Homo sapiens P68104
Anti Tag CoIP
16828757
Intra
ZBTB16 Q05516 TRAF2 Homo sapiens Q12933
Validated Y2H
32296183
Intra
ZBTB16 Q05516 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
ZBTB16 Q05516 TRAF2 Homo sapiens Q12933
Y2H Pooling
16189514
Intra
ZBTB16 Q05516 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 YWHAE Homo sapiens P62258
Crosslink
36931259
Intra
ZBTB16 Q05516 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TRAF1 Homo sapiens Q13077
Validated Y2H
32296183
Intra
ZBTB16 Q05516 TRAF1 Homo sapiens Q13077
BFG-2H
27107012
Intra
ZBTB16 Q05516 TRAF1 Homo sapiens Q13077
Y2H Array
32296183
Intra
ZBTB16 Q05516 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra
ZBTB16 Q05516 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
32296183
Intra
ZBTB16 Q05516 COG6 Homo sapiens Q9Y2V7
BFG-2H
27107012
Intra
ZBTB16 Q05516 COG6 Homo sapiens Q9Y2V7
Y2H Array
32296183
Intra
ZBTB16 Q05516 COG6 Homo sapiens Q9Y2V7
Validated Y2H
32296183
Intra
ZBTB16 Q05516 COG6 Homo sapiens Q9Y2V7
Y2H Prey Pooling
32296183
Cross
ZBTB16 Q05516 Hoxa1 Mus musculus P09022
Y2H
23088713
Intra
ZBTB16 Q05516 ZNF620 Homo sapiens Q6ZNG0
Validated Y2H
32296183
Intra
ZBTB16 Q05516 ZNF620 Homo sapiens Q6ZNG0
Y2H Array
32296183
Intra
ZBTB16 Q05516 ZNF620 Homo sapiens Q6ZNG0
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 HTT Homo sapiens P42858
Y2H
17500595
Intra
ZBTB16 Q05516 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
ZBTB16 Q05516 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
ZBTB16 Q05516 GOLGA2 Homo sapiens Q08379
BFG-2H
27107012
Intra
ZBTB16 Q05516 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra
ZBTB16 Q05516 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
Intra
ZBTB16 Q05516 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
Intra
ZBTB16 Q05516 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
ZBTB16 Q05516 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 FAM90A1 Homo sapiens Q86YD7
Validated Y2H
32296183
Intra
ZBTB16 Q05516 MYLIP Homo sapiens Q8WY64
Validated Y2H
32296183
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Pull Down
9294197
Intra
ZBTB16 Q05516 LAMTOR5 Homo sapiens O43504
Y2H Prey Pooling
25416956
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Y2H
9294197
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 LAMTOR5 Homo sapiens O43504
Validated Y2H
25416956
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Validated Y2H
32296183
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Y2H Array
25416956
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
BFG-2H
27107012
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Y2H Array
32296183
Intra
ZBTB16 Q05516 ZBTB16 Homo sapiens Q05516
Validated Y2H
27107012
Intra
ZBTB16 Q05516 TRIM27 Homo sapiens P14373
BFG-2H
27107012
Intra
ZBTB16 Q05516 RINT1 Homo sapiens Q6NUQ1
Y2H Array
32296183
Intra
ZBTB16 Q05516 RINT1 Homo sapiens Q6NUQ1
Validated Y2H
32296183
Intra
ZBTB16 Q05516 RINT1 Homo sapiens Q6NUQ1
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ZBTB16 Q05516 CEP70 Homo sapiens Q8NHQ1
Y2H Pooling
16189514
Intra
ZBTB16 Q05516 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
ZBTB16 Q05516 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
ZBTB16 Q05516 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 VTA1 Homo sapiens Q9NP79
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 VTA1 Homo sapiens Q9NP79
Y2H Array
32296183
Intra
ZBTB16 Q05516 VTA1 Homo sapiens Q9NP79
Y2H Pooling
16189514
Intra
ZBTB16 Q05516 VTA1 Homo sapiens Q9NP79
Validated Y2H
32296183
Intra
ZBTB16 Q05516 LDOC1 Homo sapiens O95751
Y2H Array
32296183
Intra
ZBTB16 Q05516 LDOC1 Homo sapiens O95751
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 LDOC1 Homo sapiens O95751
Y2H Pooling
16189514
Intra
ZBTB16 Q05516 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra
ZBTB16 Q05516 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 NME4 Homo sapiens O00746
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 NME4 Homo sapiens O00746
Y2H Array
32296183
Intra
ZBTB16 Q05516 AMOTL2 Homo sapiens Q9Y2J4
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 AMOTL2 Homo sapiens Q9Y2J4
Validated Y2H
32296183
Intra
ZBTB16 Q05516 AMOTL2 Homo sapiens Q9Y2J4
Y2H Array
32296183
Intra
ZBTB16 Q05516 FHL5 Homo sapiens Q5TD97
Validated Y2H
32296183
Intra
ZBTB16 Q05516 FHL5 Homo sapiens Q5TD97
Y2H Array
32296183
Intra
ZBTB16 Q05516 FHL5 Homo sapiens Q5TD97
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 CTDSP1 Homo sapiens Q9GZU7
Validated Y2H
32296183
Intra
ZBTB16 Q05516 CTDSP1 Homo sapiens Q9GZU7
Y2H Array
32296183
Intra
ZBTB16 Q05516 CTDSP1 Homo sapiens Q9GZU7
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TRIM21 Homo sapiens P19474
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TRIM21 Homo sapiens P19474
Y2H Array
32296183
Intra
ZBTB16 Q05516 TTC23 Homo sapiens Q5W5X9-3
Y2H Array
32296183
Intra
ZBTB16 Q05516 TTC23 Homo sapiens Q5W5X9-3
Y2H Prey Pooling
32296183
Intra
ZBTB16 Q05516 TTC23 Homo sapiens Q5W5X9-3
Validated Y2H
32296183
Cross
ZBTB16 Q05516 Gne Rattus norvegicus O35826
Pull Down
17118363
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Skeletal Defects, Genital Hypoplasia, And Impaired Intellectual Development

Skeletal Defects, Genital Hypoplasia, And Mental Retardation

SGYMR
Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic
Precursor T-Cell Acute Lymphoblastic Leukemia

T-All

Precursor T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Precursor T-Cell Acute Lymphocytic Leukemia

Precursor T-Cell Acute Lymphocytic Leukemia/Lymphoma

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Adult T-Cell Lymphoma/Leukemia
Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153698 CC-3060 99.7% Unkown
HY-RS15964 ZBTB16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ZBTB16 VGNC VGNC:81091
Bos taurus ZBTB16 VGNC VGNC:37062
Rattus norvegicus ZBTB16 RGD RGD:727921
Macaca mulatta ZBTB16 VGNC VGNC:78845
Canis familiaris ZBTB16 VGNC VGNC:48524
Mus musculus ZBTB16 MGD MGI:103222