2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Imiloxan hydrochloride

Imiloxan hydrochloride  (Synonyms: RS 21361)

Cat. No.: HY-101337A Purity: 98.47%
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Imiloxan hydrochloride is a potent and selective alpha 2B-adrenoceptor antagonist. Imiloxan hydrochloride has the potential for acute kidney injury research.

For research use only. We do not sell to patients.

Imiloxan hydrochloride Chemical Structure

Imiloxan hydrochloride Chemical Structure

CAS No. : 81167-22-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Imiloxan hydrochloride:

Imiloxan hydrochloride Related Antibodies

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α adrenergic receptor β adrenergic receptor

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Description

Imiloxan hydrochloride is a potent and selective alpha 2B-adrenoceptor antagonist. Imiloxan hydrochloride has the potential for acute kidney injury research[1][2].

Molecular Weight

280.75

Formula

C14H17ClN2O2
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

CCN1C=CN=C1CC2OC3=CC=CC=C3OC2.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (445.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5619 mL 17.8094 mL 35.6189 mL
5 mM 0.7124 mL 3.5619 mL 7.1238 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5619 mL 17.8094 mL 35.6189 mL 89.0472 mL
5 mM 0.7124 mL 3.5619 mL 7.1238 mL 17.8094 mL
10 mM 0.3562 mL 1.7809 mL 3.5619 mL 8.9047 mL
15 mM 0.2375 mL 1.1873 mL 2.3746 mL 5.9365 mL
20 mM 0.1781 mL 0.8905 mL 1.7809 mL 4.4524 mL
25 mM 0.1425 mL 0.7124 mL 1.4248 mL 3.5619 mL
30 mM 0.1187 mL 0.5936 mL 1.1873 mL 2.9682 mL
40 mM 0.0890 mL 0.4452 mL 0.8905 mL 2.2262 mL
50 mM 0.0712 mL 0.3562 mL 0.7124 mL 1.7809 mL
60 mM 0.0594 mL 0.2968 mL 0.5936 mL 1.4841 mL
80 mM 0.0445 mL 0.2226 mL 0.4452 mL 1.1131 mL
100 mM 0.0356 mL 0.1781 mL 0.3562 mL 0.8905 mL
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Imiloxan hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Imiloxan81167-22-8RS 21361RS21361RS-21361Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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