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The Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) is a humanized antibody expressed in CHO cells, targeting CDH17/Cadherin-17. The Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) features an IgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 149.12 kDa. The isotype control for the Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH17/Cadherin-17 Antibody (10C12) is a human antibody expressed in CHO cells, targeting CDH17. Anti-CDH17/Cadherin-17 Antibody (10C12) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH1/E-cadherin/CD324 Antibody is a humanized antibody expressed in CHO, targeting CDH1/E-cadherin/CD324. The Anti-CDH1/E-cadherin/CD324 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.6 kDa. The isotype control for Anti-CDH1/E-cadherin/CD324 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) is a human antibody expressed in CHO cells, targeting CDH6. Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
SLEC-11 is a CDH1/E-cadherin modulator that potently inhibits cell death in E-cadherin-deficient cells (EC50=8.2 μM). SLEC-11 can be used to study potential synthetic lethal therapies for gastric cancer .
FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS) .
AW01178 is a Class I HDAC inhibitor. AW01178 induces the upregulation of E-cadherin at both mRNA and protein levels and inhibits the EMT of breast cancer cells .
Ovalitenone is a flavonoid compound that can be isolated from the plant Millettia peguensis. It shows no cytotoxic effects on lung cancer H460 and A549 cells, but it significantly inhibits anchorage-independent growth, CSC-like phenotypes, colony formation, and the migration and invasion capabilities of cancer cells. Ovalitenone can significantly reduce the levels of N-cadherin, snail, and slug, while increasing E-cadherin, thus inhibiting the EMT pathway. Additionally, Ovalitenone suppresses the signaling pathways regulated by focal adhesion kinase (FAK), ATP-dependent tyrosine kinase (AKT), mammalian target of rapamycin (mTOR), and cell division cycle 42 (Cdc42) .
PF-03732010 is a humanized antibody expressed in CHO, targeting CDH3/P-cadherin. PF-03732010 has a huIgG1 type heavy chain and a huλ type light chain, with a predicted molecular weight (MW) of 142.7 kDa. The isotype control for PF-03732010 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong antitumor effect in mice model and exhibits no significant hepatic and renal toxicity .
AL-GDa62 is a derivative of the CDH1/E-cadherin modulator SLEC-11 (HY-145268) and induces apoptosis in CDH1 -/- cells. AL-GDa62 has an EC50 of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild type) and mutant MCF10A-CDH1 -/-, respectively. AL-GDa62 specifically inhibits TCOF1, ARPC5, and UBC9, and suppresses SUMOylation at low micromolar concentrations .
TRPM7-IN-1 (compound SUD), a benzoylurea derivative, is an effective TRPM7 inhibitor. TRPM7-IN-1 induces cell cycle arrest and apoptosis, decreases the migration of MCF-7 and BGC-823 cells. TRPM7-IN-1 decreases vimentin expression and increases E-cadherin expression. TRPM7-IN-1 potentially reduces the TRPM7-like current and decreases TRPM7 expression through the PI3K/Akt signaling pathway. TRPM7-IN-1 is a potential agent to suppress the metastasis of breast and gastric cancer by inhibiting TRPM7 expression and function .
pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide .
FX-06 (Fibrin-derived peptide Bβ15-42) is a fibrin Bbeta chain-derived peptide. FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling. FX-06 can be used in the research of ischemia/reperfusion injury, Dengue shock syndrome (DSS) .
SWELYYPLRANL-NH2 is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers .
SWELYYPLRANL-NH2 TFA is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 TFA inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 TFA inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers .
The Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) is a humanized antibody expressed in CHO cells, targeting CDH17/Cadherin-17. The Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) features an IgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 149.12 kDa. The isotype control for the Anti-CDH17/Cadherin-17 Antibody (PTA001_A4) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
RG-6125 is a humanized antibody expressed in CHO, targeting CDH11/Cadherin-11. RG-6125 has a huIgG2 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for RG-6125 can refer to Human IgG2 kappa, Isotype Control (HY-P99002).
PF-03732010 is a humanized antibody expressed in CHO, targeting CDH3/P-cadherin. PF-03732010 has a huIgG1 type heavy chain and a huλ type light chain, with a predicted molecular weight (MW) of 142.7 kDa. The isotype control for PF-03732010 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH17/Cadherin-17 Antibody (10C12) is a human antibody expressed in CHO cells, targeting CDH17. Anti-CDH17/Cadherin-17 Antibody (10C12) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH1/E-cadherin/CD324 Antibody is a humanized antibody expressed in CHO, targeting CDH1/E-cadherin/CD324. The Anti-CDH1/E-cadherin/CD324 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.6 kDa. The isotype control for Anti-CDH1/E-cadherin/CD324 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) is a human antibody expressed in CHO cells, targeting CDH6. Anti-CDH6/K-Cadherin Antibody (HKT288 antibody) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Ovalitenone is a flavonoid compound that can be isolated from the plant Millettia peguensis. It shows no cytotoxic effects on lung cancer H460 and A549 cells, but it significantly inhibits anchorage-independent growth, CSC-like phenotypes, colony formation, and the migration and invasion capabilities of cancer cells. Ovalitenone can significantly reduce the levels of N-cadherin, snail, and slug, while increasing E-cadherin, thus inhibiting the EMT pathway. Additionally, Ovalitenone suppresses the signaling pathways regulated by focal adhesion kinase (FAK), ATP-dependent tyrosine kinase (AKT), mammalian target of rapamycin (mTOR), and cell division cycle 42 (Cdc42) .
Cadherin-12/CDH12 is a calcium-dependent cell adhesion protein in the cadherin family known for its preferential homophilic interactions (binding to itself between connecting cells). This interaction is shown to play a crucial role in mediating cell adhesion and may play a key role in sorting heterogeneous cell types. Cadherin-12/CDH12 Protein, Human (HEK293, His) is the recombinant human-derived Cadherin-12/CDH12 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-12/CDH12 Protein, Human (HEK293, His) is 582 a.a., with molecular weight of 80-85 kDa.
Cadherin-13 Protein is an atypical member of the cadherin family, devoid of a transmembrane domain and anchored to the exterior surface of the plasma membrane via a glycosylphosphatidylinositol anchor. And it exhibits a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. Cadherin-13 may act as negative regulators of neural cell growth. Moreover, it may act rather as a signalling receptor participating in recognition of the environment and regulation of cell motility, proliferation and phenotype. Cadherin-13 Protein, Rat (HEK293) is the recombinant rat-derived Cadherin-13 protein, expressed by HEK293 , with tag free.
Cadherin-6/KCAD Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. It exhibits a preference for interacting with other cadherin molecules of the same type in a homophilic manner, facilitating the adhesion between connecting cells. As a calcium-dependent adhesion protein, Cadherin-6/KCAD participates in maintaining the structural integrity of tissues and regulating cellular processes such as development, differentiation, and morphogenesis. Cadherin-6/KCAD Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Rat (HEK293, His) is 597 a.a., with molecular weight of 85-95 KDa.
Cadherin-3 protein mediates cell-cell interactions by selectively binding to other cadherin molecules in a homophilic manner. This promotes adhesion between cells, aiding in the sorting and organization of different cell types. Cadherin-3 also interacts with CDCP1 and CTNNB1, regulating cellular processes and signaling pathways. Cadherin-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-3 Protein, Mouse (HEK293, His) is 548 a.a., with molecular weight of 70-80 kDa.
Cadherin-13 proteins are calcium-dependent cell adhesion molecules that exhibit a preference for homogeneous interactions, promote connections between adjacent cells, and may play a role in cell type sorting. Cadherin-13 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-13 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-13 Protein, Mouse (HEK293, His) is 692 a.a., with molecular weight of 90-110 kDa.
Cadherin-9 Protein, a calcium-dependent cell adhesion molecule, functions within cellular interactions. Exhibiting calcium-dependent adhesion, CDH9 prefers homophilic interactions, connecting cells. This unique feature suggests a potential role in sorting heterogeneous cell types. The calcium-dependent mechanism underscores cadherins' regulatory role in cellular cohesion within intercellular junctions, maintaining tissue integrity and function. Cadherin-3 Protein, Pig (P.pastoris) is the recombinant pig-derived Cadherin-3 protein, expressed by P. pastoris , with tag free.
Cadherin-6/KCAD protein acts as a calcium-dependent cell adhesion protein and mediates cell-cell interactions. They preferentially interact in the same way with other cadherin molecules of the same type, promoting adhesion between cells. Cadherin-6/KCAD Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Mouse (HEK293, His) is 597 a.a., with molecular weight of ~98 kDa.
Cadherin-13 Protein is an atypical member of the cadherin family, devoid of a transmembrane domain and anchored to the exterior surface of the plasma membrane via a glycosylphosphatidylinositol anchor. And it exhibits a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. Cadherin-13 may act as negative regulators of neural cell growth. Moreover, it may act rather as a signalling receptor participating in recognition of the environment and regulation of cell motility, proliferation and phenotype. Cadherin-13 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-13 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-13 Protein is an atypical member of the cadherin family, devoid of a transmembrane domain and anchored to the exterior surface of the plasma membrane via a glycosylphosphatidylinositol anchor. And it exhibits a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. Cadherin-13 may act as negative regulators of neural cell growth. Moreover, it may act rather as a signalling receptor participating in recognition of the environment and regulation of cell motility, proliferation and phenotype. Cadherin-13 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Cadherin-13 protein, expressed by HEK293 , with C-hFc labeled tag.
Cadherin-13 proteins are calcium-dependent cell adhesion molecules that exhibit a preference for homophilic interactions, fostering connections between neighboring cells and potentially playing a role in cell type sorting. These proteins may act as negative regulators of neural cell growth. In contrast to classical cadherins, the homodimerization of Cadherin-13 in trans does not occur through the cadherin EC1 domain strand-swapping mechanism. Instead, it takes place through a homophilic adhesive interface, bringing together two elongated EC1-EC2 domains in close proximity to their Ca2+-binding sites, forming a distinctive tetrahedral, X-like shape. Cadherin-13 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Cadherin-13 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-13 Protein, Mouse (HEK293, Fc) is 692 a.a., with molecular weight of ~100.6 kDa.
Cadherin-11 Protein, Human (HEK293, His) is a recombinant human Cadherin-11 produced in HEK293 cells, with His tag. Cadherin-11 is a classical cadherin adhesion molecule that mediates homophilic cell-to-cell adhesion.
Cadherin-3 protein, a calcium-dependent adhesion molecule, facilitates cell interactions. It prefers homophilic interaction with other cadherin-3 proteins, aiding cell connection. This interaction helps sort and organize cell types. Cadherin-3 also interacts with CDCP1 and CTNNB1, impacting cellular processes. Cadherin-3 Protein, Human (547a.a, HEK293, His) is the recombinant human-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-3 Protein, Human (547a.a, HEK293, His) is 547 a.a., with molecular weight of 70-80 kDa.
Cadherin-9 Protein, a calcium-dependent cell adhesion molecule, functions within cellular interactions. Exhibiting calcium-dependent adhesion, CDH9 prefers homophilic interactions, connecting cells. This unique feature suggests a potential role in sorting heterogeneous cell types. The calcium-dependent mechanism underscores cadherins' regulatory role in cellular cohesion within intercellular junctions, maintaining tissue integrity and function. Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is the recombinant cynomolgus-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is 547 a.a., with molecular weight of 70-80 kDa.
Cadherin-1/CD324 Protein, a calcium-dependent receptor on myeloid cells, binds to carbohydrates on neutrophils and monocytes. It facilitates interaction between activated endothelial cells or platelets with leukocytes. It recognizes sialyl-Lewis X as its ligand. Through interaction with SELPLG, it mediates rapid leukocyte rolling in early inflammation. Cadherin-1/CD324 Protein also interacts with SNX17 and facilitates neutrophil adhesion and rolling, depending on sialyl-Lewis X epitope and tyrosine sulfation. Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is 554 a.a., with molecular weight of 68-78 kDa.
Cadherin-6/KCAD Proteinas are calcium-dependent cell adhesion proteins that facilitate cell-to-cell interactions. They preferentially bind to other cadherins of the same type, promoting homophilic interactions. This aids in the organization and sorting of various cell types within tissues. Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is the recombinant human-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is 562 a.a., with molecular weight of 75-95 kDa.
Cadherin-17 Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. Employing preferential homophilic interactions, Cadherin-17 facilitates self-binding between connecting cells. With its calcium-dependent adhesion properties, Cadherin-17 actively participates in establishing selective connections between cells, influencing the dynamic regulation of cellular interactions and contributing to the overall structural integrity of tissues, particularly in the liver and intestine. Cadherin-17 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-17 protein mediates cell-cell interactions by selectively binding to other cadherin-17 proteins in a homophilic manner. This interaction promotes connections between adjacent cells and helps sort and organize different cell types within the tissue. Cadherin-17 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-17 Protein, Mouse (HEK293, His) is 761 a.a., with molecular weight of 90-115 kDa.
Cadherin-18, a calcium-dependent cell adhesion protein and member of the cadherin family, regulates cellular adhesion processes. Cadherin-18 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Cadherin-18 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-17 protein is a calcium-dependent cell adhesion member that plays a crucial role in cell adhesion through self-association. Cadherin-17 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-17 Protein, Rhesus macaque (HEK293, His) is 762 a.a., with molecular weight of 90-110 kDa.
Cadherin-3 Protein, Mouse (HEK293, Fc) is a recombinant mouse Cadherin-3 (P-cadherin) produced in HEK293 cells, with an Fc fragment at the C-terminus. Cadherin-3 is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues.
Cadherin-17 Protein, Human (765a.a, HEK293, His) is a recombinant human Cadherin-17 produced in HEK293 cells, with His tag. Cadherin-17 is a calcium-dependent transmembrane glycoprotein that mediates cell-cell adhesion in intestinal epithelium.
Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Human (765a.a, HEK293, hFc) is 765 a.a., with molecular weight of 113-135 kDa.
Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (328a.a, HEK293, His) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-17 Protein, Human (328a.a, HEK293, His) is 328 a.a., with molecular weight of 50-70 kDa.
Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (215a.a, HEK293, His) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-17 Protein, Human (215a.a, HEK293, His) is 215 a.a., with molecular weight of 35-45 kDa.
Cadherin-6/KCAD Protein, Human (HEK293, Fc), a recombinant human Cadherin-6 produced in HEK293 cells, has an Fc fragment at the C-terminus. Cadherin-6 (CDH6) is a type 2 cadherin, which drives epithelial cells toward a mesenchymal condition (EMT) during embryonic development and it is aberrantly re-activated in cancer.
Cadherin-11, a calcium-dependent cell adhesion protein, belongs to the cadherin family. Cadherin-11 Protein, Human (564a.a, HEK293, His) is the recombinant human-derived Cadherin-11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-11 Protein, Human (564a.a, HEK293, His) is 564 a.a., with molecular weight of 67-70 kDa.
Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (Biotinylated, 328a.a, HEK293, His) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-17 Protein, Human (Biotinylated, 328a.a, HEK293, His) is 328 a.a., with molecular weight of 50-70 kDa.
Cadherin-3 Protein, Human (630a.a, HEK293, His) is a recombinant human Cadherin-3 (P-cadherin) produced in HEK293 cells, with His tag. Cadherin-3 is a classical cell-to-cell adhesion molecule with a homeostatic function in several normal tissues.
Cadherin-17 protein mediates cell-cell interactions, sorting and organizing heterogeneous cell types by preferentially binding to other Cadherin-17 molecules. LI-cadherin, a subtype of Cadherin-17, is implicated in liver and intestinal morphological organization. Cadherin-17 also facilitates intestinal peptide transport, emphasizing its functional significance. Cadherin-17 Protein, Human (Biotinylated, 765a.a, HEK293, His-Avi) is the recombinant human-derived Cadherin-17 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Cadherin-17 Protein, Human (Biotinylated, 765a.a, HEK293, His-Avi) is 765 a.a., with molecular weight of 105-120 kDa.
Cadherin-8, a calcium-dependent cell adhesion protein, participates in homophilic interactions, potentially aiding the sorting of diverse cell types. Its ability for preferential homophilic interaction underscores its role in mediating cell-cell adhesions and implies involvement in cellular organization and coordination. Cadherin-8 Protein, Rat (HEK293) is the recombinant rat-derived Cadherin-8 protein, expressed by HEK293 , with tag free.
Cadherin-6 Protein, Human (594a.a, HEK293, His), a recombinant human Cadherin-6 produced in HEK293 cells, has a His tag at the N-terminus. Cadherin-6 (CDH6) is a type 2 cadherin, which drives epithelial cells toward a mesenchymal condition (EMT) during embryonic development and it is aberrantly re-activated in cancer.
Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is 690 a.a., with molecular weight of 95-130 kDa.
The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag.
The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is 685 a.a., with molecular weight of ~87.1 KDa.
Cadherin-1/CD324 is a calcium-dependent cell adhesion protein that orchestrates homogeneous interactions, promoting cell cohesion and potential cell type sorting. CDH1 regulates epithelial cell adhesion, mobility, and proliferation and acts as an invasive suppressor. Cadherin-1/CD324 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-6*His labeled tag.
Cadherin-8, a calcium-dependent cell adhesion protein, participates in homophilic interactions, potentially aiding the sorting of diverse cell types. Its ability for preferential homophilic interaction underscores its role in mediating cell-cell adhesions and implies involvement in cellular organization and coordination. Cadherin-8 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-8 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-8 Protein, Human (HEK293, His), a recombinant human Cadherin-8 produced in HEK293 cells, has a His tag at the N-terminus. Cadherin-8 (Cdh8) is a classical type II cadherin that can bind β-catenin and has a role in the migration and growth of other neuronal cell types.
Cadherin-1/CD324 Protein, Human (HEK293, His) is a recombinant human E-cadherin produced in HEK293 cells, with His tag. Cadherin-1/CD324/E-cadherin is one of the most important molecules in cell-cell adhesion in epithelial tissues.
Cadherin-17 protein is a calcium-dependent cell adhesion member that plays a crucial role in cell adhesion through self-association. Cadherin-17 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-17 Protein, a member of the calcium-dependent cell adhesion protein family, assumes a crucial role in mediating cellular adhesion. Employing preferential homophilic interactions, Cadherin-17 facilitates self-binding between connecting cells. With its calcium-dependent adhesion properties, Cadherin-17 actively participates in establishing selective connections between cells, influencing the dynamic regulation of cellular interactions and contributing to the overall structural integrity of tissues, particularly in the liver and intestine. Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived Cadherin-17 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-17 Protein, Cynomolgus (HEK293, Fc) is 787 a.a., with molecular weight of ~111.8 KDa.
CDH16, a calcium-dependent cell adhesion protein, belongs to the cadherin family. It exhibits homophilic interactions, potentially contributing to cell-type sorting and regulating cell-cell adhesions for cellular organization. CDH16 Protein, Human (HEK293, His) is the recombinant human-derived CDH16 protein, expressed by HEK293 , with C-His labeled tag. The total length of CDH16 Protein, Human (HEK293, His) is 768 a.a., with molecular weight of 90-110 kDa.
The R-Cadherin/CDH4 protein facilitates cell adhesion through homophilic interactions, aiding in cell connections and potential cell type sorting. It may play a crucial role in retinal development, indicating its significance in orchestrating cellular processes within the context of eye development and function. R-Cadherin/CDH4 Protein, Human (HEK293, His) is the recombinant human-derived R-Cadherin/CDH4 protein, expressed by HEK293 , with C-His labeled tag. The total length of R-Cadherin/CDH4 Protein, Human (HEK293, His) is 714 a.a., with molecular weight of 90-100 kDa.
K-Cadherin/CDH6, a calcium-dependent cell adhesion protein, shows significant transcriptional expression in hepatocellular and renal carcinoma cell lines, hinting at potential involvement in metastasis and invasion. K-Cadherin/CDH6 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived K-Cadherin/CDH6 protein, expressed by HEK293 , with C-His labeled tag.
VE-cadherin is critical for cellular functions such as β-catenin binding and signaling receptor activity, and is involved in processes such as cell-cell junction organization and vascular maturation. It is predicted to localize in cell-cell junctions and nuclei, serving as a biomarker for pulmonary hypertension. VE-Cadherin Protein, Rat (HEK293, His) is the recombinant rat-derived VE-Cadherin protein, expressed by HEK293 , with C-His labeled tag. The total length of VE-Cadherin Protein, Rat (HEK293, His) is 561 a.a., with molecular weight of ~80-95 kDa.
VE-cadherin is a calcium-dependent glycoprotein critical for mediating cell adhesion and coordinating morphogenetic events during development. Lack of VE-cadherin in mice leads to uterine death due to increased endothelial cell apoptosis leading to vascular insufficiency. VE-Cadherin Protein, Mouse (HEK293, His) is the recombinant mouse-derived VE-Cadherin protein, expressed by HEK293 , with C-10*His labeled tag.
N-Cadherin Protein forms dimers with CDH2 chains, promoting cell-cell adhesion and sorting of cell types. It regulates neural stem cell quiescence by anchoring them to ependymocytes, disrupted by MMP24 cleavage. It also promotes cell-to-cell junctions and neurite branching, and regulates dendritic spine density. N-Cadherin Protein interacts with CDCP1, PCDH8, OBSCN, FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43, CTTN, and FBXO45. N-Cadherin Protein, Human (699a.a, HEK293, His) N-Cadherin Protein, Human (HEK293, His) is the recombinant human-derived N-Cadherin protein, expressed by HEK293 , with C-His labeled tag.
The FGFR-4 protein binds to its ligands and activates signaling pathways involved in cell growth, differentiation, and survival. It plays a role in various developmental processes, including skeletal development, liver metabolism, and cancer progression. In the absence of ligand binding, FGFR-4 remains inactive and does not initiate downstream signaling cascades. VE-Cadherin Protein, Human (HEK293, C-His-Fc) is the recombinant human-derived VE-Cadherin protein, expressed by HEK293 , with C-hFc, C-6*His labeled tag. The total length of VE-Cadherin Protein, Human (HEK293, C-His-Fc) is 568 a.a., with molecular weight of ~125 kDa.
N-Cadherin Protein is a calcium-dependent cell adhesion protein that mediates homotypic cell-cell adhesion by dimerizing with a CDH2 chain from another cell. N-Cadherin Protein plays a role in cell adhesion, cell sorting, and neural development. N-Cadherin Protein, Mouse (HEK293) is the recombinant mouse-derived N-Cadherin protein, expressed by HEK293 , with tag free. The total length of N-Cadherin Protein, Mouse (HEK293) is 699 a.a., with molecular weight of ~91 & 114 kDa, respectively.
CDH19 Protein, a calcium-dependent cell adhesion protein, engages in homophilic interactions, primarily connecting cells. This adhesive property suggests a potential role for cadherins, including CDH19, in facilitating the sorting of diverse cell types. CDH19 Protein, Human (Flag-MBP) is the recombinant human-derived CDH19 protein, expressed by E. coli , with N-MBP, N-Flag labeled tag. The total length of CDH19 Protein, Human (Flag-MBP) is 526 a.a., with molecular weight of 100.89 kDa.
The PCDH1 protein has been implicated in cell-cell interactions and adhesion, suggesting a role in important cellular processes. Its involvement in cell adhesion highlights its importance in forming and maintaining cell junctions. PCDH1 Protein, Human (HEK293, His) is the recombinant human-derived PCDH1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PCDH1 Protein, Human (HEK293, His) is 795 a.a., with molecular weight of ~120.0 kDa.
DSC2/Desmocollin-2 protein is vital for intercellular desmosome junctions, mediating adhesion by interacting with plaque proteins and intermediate filaments. It also regulates cell positioning and interacts with DSP, PKP2, and JUP, strengthening junction stability. Overall, DSC2/Desmocollin-2 protein maintains tissue organization and functionality. DSC2/Desmocollin-2 Protein, Human (HEK293, His) is the recombinant human-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DSC2/Desmocollin-2 Protein, Human (HEK293, His) is 657 a.a., with molecular weight of ~85 & 100 KDa, respectively.
DSC2 (or Desmocollin-2) is an important component of desmosome connections between cells and plays a key role in the complex interaction network between plaque proteins and intermediate filaments. At these junctions, DSC2 contributes to cell-cell adhesion, promoting tissue cohesion and stability. DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is 666 a.a., with molecular weight of ~101.6 KDa.
DSC2 (or Desmocollin-2) is an important component of desmosome connections between cells and plays a key role in the complex interaction network between plaque proteins and intermediate filaments. At these junctions, DSC2 contributes to cell-cell adhesion, promoting tissue cohesion and stability. DSC2/Desmocollin-2 Protein, Rat (HEK293, His) is the recombinant rat-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of DSC2/Desmocollin-2 Protein, Rat (HEK293, His) is 666 a.a., with molecular weight of ~80-95 KDa, respectively.
DSC2/Desmocollin-2 protein is vital for intercellular desmosome junctions, mediating adhesion by interacting with plaque proteins and intermediate filaments. It also regulates cell positioning and interacts with DSP, PKP2, and JUP, strengthening junction stability. Overall, DSC2/Desmocollin-2 protein maintains tissue organization and functionality. DSC2/Desmocollin-2 Protein, Human (HEK293, C-His) is the recombinant human-derived DSC2/Desmocollin-2, expressed by HEK293 , with C-10*His labeled tag. The total length of DSC2/Desmocollin-2 Protein, Human (HEK293, C-His) is 657 a.a.,
CTNNA1 Protein, Human (sf9, GST) is the recombinant human-derived CTNNA1, expressed by Sf9 insect cells , with GST labeled tag. The total length of CTNNA1 Protein, Human (sf9, GST) is 906 a.a.,
DSG3 is a component of intercellular desmosome junctions and plays a key role in promoting intercellular adhesion by participating in important interactions with plaque proteins and intermediate filaments. Carefully orchestrated interactions between DSG3 and these structural elements are critical for maintaining the integrity and strength of cell-to-cell connections. DSG3 Protein, Human (Sf9, His) is the recombinant human-derived DSG3 protein, expressed by Sf9 insect cells , with C-6*His labeled tag.
HLA-A*0201 MAGE-A3 Complex Protein, a vital member of the major histocompatibility complex (MHC) class I family, facilitates immune recognition and response to hepatitis B virus (HBV). By presenting HBV-derived peptides to cytotoxic T cells, it contributes to antiviral defense mechanisms within the MHC class I pathway, emphasizing its pivotal role in adaptive immunity and immune system surveillance against infected or aberrant cells. HLA-A*0101 DSG3 Complex Protein, Human (NTDNNLAVY, HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-A*0101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and YTDNWLAVY peptide. HLA-A*0101 DSG3 Complex Protein, Human (NTDNNLAVY, HEK293, His-Avi), has molecular weight of 52-62 kDa.
DSG3 is a component of intercellular desmosome junctions and plays a key role in promoting intercellular adhesion by participating in important interactions with plaque proteins and intermediate filaments. Carefully orchestrated interactions between DSG3 and these structural elements are critical for maintaining the integrity and strength of cell-to-cell connections. DSG3 Protein, Human (His-SUMO) is the recombinant human-derived DSG3 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of DSG3 Protein, Human (His-SUMO) is 566 a.a., with molecular weight of ~79 kDa.
CDH13; CDHH; H-Cadherin; Heart Cadherin; P105; T cad; T Cadherin; Truncated Cadherin
WB, IHC-P
Human, Mouse, Rat
H Cadherin Antibody (YA1470) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1470), targeting H Cadherin, with a predicted molecular weight of 78 kDa (observed band size: 105,130 kDa). H Cadherin Antibody (YA1470) can be used for WB, IHC-P experiment in human, mouse, rat background.
P-Cadherin Antibody (YA1535) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1535), targeting P-Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 130-150 kDa). P-Cadherin Antibody (YA1535) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.
N Cadherin Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 100 kDa, targeting to N Cadherin. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.
E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.
Cadherin 4; type 1; R-Cadherin (retinal); CAD4; RCAD; R-CAD
WB, IP
Human, Mouse, Rat
R Cadherin Antibody (YA1844) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1844), targeting R Cadherin, with a predicted molecular weight of 100 kDa (observed band size: 130 kDa). R Cadherin Antibody (YA1844) can be used for WB, IP experiment in human, mouse, rat background.
Cadherin 16 Antibody (YA1476) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1476), targeting Cadherin 16, with a predicted molecular weight of 90 kDa (observed band size: 120 kDa). Cadherin 16 Antibody (YA1476) can be used for WB, IHC-P, IP experiment in human, mouse background.
Cadherin 10 Antibody (YA2764) is a non-conjugated IgG antibody, targeting Cadherin 10, with a predicted molecular weight of 88 kDa (observed band size: 110 kDa). Cadherin 10 Antibody (YA2764) can be used for WB experiment in human, mouse, rat background.
LI Cadherin Antibody (YA1709) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1709), targeting LI Cadherin, with a predicted molecular weight of 92 kDa (observed band size: 120 kDa). LI Cadherin Antibody (YA1709) can be used for WB, IHC-P, IP experiment in human background.
P cadherin Antibody (YA1234) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1234), targeting P cadherin. P cadherin Antibody (YA1234) can be used for IHC-P experiment in human background.
Pan-Cadherin Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 100 kDa, targeting to Pan-Cadherin. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse, Rat.
CD144/VE Cadherin Antibody is an unconjugated, approximately 88 kDa, rabbit-derived, anti-CD144/VE Cadherin monoclonal antibody. CD144/VE Cadherin Antibody can be used for: WB, IF-Cell, FC expriments in human, mouse, rat, background without labeling.
Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2579), targeting Phospho-E Cadherin (Ser838/Ser840), with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) can be used for WB, IHC-P, IP experiment in human, mouse background.
E-Cadherin Antibody (YA778) is a non-conjugated and Mouse origined monoclonal antibody about 97 kDa, targeting to E-Cadherin. It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse.
E-Cadherin Antibody (YA470) is a non-conjugated and Rabbit origined monoclonal antibody about 97 kDa, targeting to E-Cadherin. It can be used for WB,ICC/IF,IHC-P,FC,IP assays with tag free, in the background of Human.
Desmocollin 3 Antibody (YA1702) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1702), targeting Desmocollin 3, with a predicted molecular weight of 100 kDa (observed band size: 100 kDa). Desmocollin 3 Antibody (YA1702) can be used for WB, ICC/IF experiment in human background.
CTNNA1 Antibody (YA2057) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2057), targeting CTNNA1, with a predicted molecular weight of 100 kDa (observed band size: 100 kDa). CTNNA1 Antibody (YA2057) can be used for WB, IP experiment in human, mouse, rat background.
CTNNA3 Antibody (YA3001) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3001), targeting CTNNA3, with a predicted molecular weight of 100 kDa (observed band size: 100 kDa). CTNNA3 Antibody (YA3001) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.
Desmoglein-1; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen; Cadherin family member 4; DSG1; CDHF4
WB, IHC-P, ICC/IF
Human, Mouse, Rat
Desmoglein 1 Antibody (YA2873) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2873), targeting Desmoglein 1, with a predicted molecular weight of 114 kDa (observed band size: 114 kDa). Desmoglein 1 Antibody (YA2873) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat background.
AW01178 is a Class I HDAC inhibitor. AW01178 induces the upregulation of E-cadherin at both mRNA and protein levels and inhibits the EMT of breast cancer cells .
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