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Hydroxy Pioglitazone-d<sub>5</sub> (M-IV) (Mixture of-diastereomers)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (1) 5-HT Receptor (1) Antibiotic (3) Antifolate (1) Bacterial (2) Biochemical Assay Reagents (6) Cholinesterase (ChE) (1) COX (1) Drug Metabolite (7) Endogenous Metabolite (11) Epigenetic Reader Domain (1) Ferroptosis (7) FLT3 (1) Fluorescent Dye (7) Fungal (2) Glucocorticoid Receptor (1) Histone Methyltransferase (1) HIV Protease (1) Isotope-Labeled Compounds (31) LXR (2) Microtubule/Tubulin (1) MMP (1) Nucleoside Antimetabolite/Analog (1) Parasite (1) PPAR (8) Prostaglandin Receptor (1) Reactive Oxygen Species (3) Serotonin Transporter (1) Telomerase (1) Thymidylate Synthase (1) TRP Channel (1) VD/VDR (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (4) Endocrinology (3) Infection (8) Inflammation/Immunology (8) Metabolic Disease (14) Neurological Disease (4)
Click Chemistry:	Alkynes (1)

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Fluorescent Dye

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Isotope-Labeled Compounds

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Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132379S

Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers)	Isotope-Labeled Compounds	Others
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-134670S

*α-Hydroxy* Metoprolol-d5 (Mixture of Diastereomers)**	Isotope-Labeled Compounds	Others
α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].

HY-132676S

*Ramiprilat-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-W653769

*Deltamethrin-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
Deltamethrin-d5 (Mixture of Diastereomers) is the deuterium labeled Deltamethrin (Mixture of Diastereomers) .

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-W742256

*N-Nitroso nebivolol (mixture* of diastereomers)**	Others	Cancer
N-Nitroso nebivolol (mixture of diastereomers) is a nitrosamine and mutagenic .

HY-144145S

Hydroxy Pioglitazone (M-II)-d4	Isotope-Labeled Compounds	Others
Hydroxy Pioglitazone (M-II)-d₄ is the deuterium labeled Hydroxy Pioglitazone (M-II)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**	Endogenous Metabolite Isotope-Labeled Compounds	Others
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)** DS5565-¹³C<sub>2sub>,d<sub>1sub> (Mixture of diastereomers)	Isotope-Labeled Compounds	Others
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-13956C

(R)-Pioglitazone (R)-U 72107	PPAR	Neurological Disease
(R)-Pioglitazone ((+)-pioglitazone) is the R enantiomer of Pioglitazone (HY-13956). (R)-Pioglitazone is an orally active and selective peroxisome proliferator-activated receptor (PPARγ) agonist with high affinity binding to the PPARγ ligand-binding domain. (R)-Pioglitazone can be used for the research of Alzheimer's disease .

HY-134818

ML-SI1 5 Publications Verification	TRP Channel	Neurological Disease
ML-SI1, a racemic mixture of diastereomers, is a TRPML inhibitor with an IC₅₀ value of 15 μM for TRPML1 .

HY-13956S

Pioglitazone-d4 U 72107-d<sub>4sub>	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone-d₄ is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].

HY-132382S

*β-Sitosterol-d7 (mixture* of diasteromers)**	Isotope-Labeled Compounds	Others
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].

HY-113679

Ceramides Mixture 1 Publications Verification	Telomerase	Metabolic Disease Endocrinology
Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .

HY-13956R

Pioglitazone (Standard)	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone (Standard) is the analytical standard of Pioglitazone. This product is intended for research and analytical applications. Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC₅₀ of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .

HY-W008216S

HMMNI-d3 Hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Infection
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-13956A

*(R)-Pioglitazone-d1* (R)-U 72107-d<sub>1sub>	Endogenous Metabolite	Inflammation/Immunology
(R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities.

HY-13956S1

Pioglitazone-d4 (alkyl)	Isotope-Labeled Compounds PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone-d₄ (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1][2].

HY-132468S

*Keto Pioglitazone-d4 (M-III-d4)*	Isotope-Labeled Compounds	Others
Keto Pioglitazone-d4 (M-III-d4) is the deuterium labeled Keto Pioglitazone (M-III) .

HY-115871A

(Rac)-PDE4-IN-4	Others	Others
(Rac)-PDE4-IN-4 is the diastereomer mixture of PDE4-IN-4 (HY-115871). PDE4-IN-4 is a dual M3 (pIC₅₀ = 10.2) antagonist-PDE4 (pIC₅₀ = 8.8) inhibitor for the inhaled research of pulmonary diseases .

HY-W008216

HMMNI Hydroxy Dimetridazole	Drug Metabolite	Others
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections .

HY-13956

*Pioglitazone* Maximum Cited Publications 29 Publications Verification U 72107	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC₅₀ of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .

HY-13956B

Pioglitazone potassium U 72107 potassium	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC₅₀ of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium can be used in diabetes research .

HY-14601R

Pioglitazone hydrochloride (Standard) U 72107A (Standard); AD 4833 (Standard)	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone (hydrochloride) (Standard) is the analytical standard of Pioglitazone (hydrochloride). This product is intended for research and analytical applications. Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC₅₀s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.

HY-115867A

(S)-GSK852	Epigenetic Reader Domain	Cancer
(S)-GSK852 is a diastereomer of GSK852 (HY-115867). GSK852 is a BET inhibitor targeting BD2 (pIC₅₀=7.9) .

HY-10792A

*Eplivanserin (mixture)* SR-46349 (Mixture)	Serotonin Transporter 5-HT Receptor	Neurological Disease
Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT_2A receptor antagonist, extracted from patent WO 2005/002578 A1 .

HY-14601

Pioglitazone hydrochloride Maximum Cited Publications 29 Publications Verification U 72107A; AD 4833	PPAR Ferroptosis	Metabolic Disease Cancer
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC₅₀s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively.

HY-N7265

Epi-galantamine	Cholinesterase (ChE)	Neurological Disease
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC₅₀ of 45.7 μM .

HY-D1249

*Calcein (mixture* of isomers)**	Fluorescent Dye	Others
Calcein mixture of isomers is a calcium-dependent fluorescent molecule. Calcein mixture of isomers can be used to study bone metabolism (in vivo) and to stain depressed areas (in vitro). Calcein mixture of isomers can also be used for fluorometry and EDTA titration of calcium.

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-Hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-131010

*Flutax-2 (5/6-mixture)*	Fluorescent Dye Microtubule/Tubulin	Cancer
Flutax-2 (5/6-mixture) is an active fluorescent derivative of paclitaxel. Flutax-2 (5/6-mixture) binds to a polymerized α,β tubulin dimer. Excitation/emission wavelength: 496/524 nm. Paclitaxel, a diterpenoid secondary metabolite produced by Taxus species, can be used for the research of a variety of cancers .

HY-14620A

*Farnesene (mixture* of isomers)**	Others	Others
Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species .

HY-D1093

*Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture)*	Fluorescent Dye	Others
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that is sensitive to pH. Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) can be used for measurement of intracellular pH .

HY-W763562

*Tridecanol (mixture* of isomers)**	Biochemical Assay Reagents	Others
Tridecanol (mixture of isomers) is a biochemical reagent.

HY-130017

*HKSOX-1r (5/6-mixture)*	Reactive Oxygen Species	Others
HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-126081

(8-epi)-BW 245C	Prostaglandin Receptor	Cardiovascular Disease
(8-epi)-BW 245C is the C-8 diastereomer of BW 245C (HY-101987). BW 245 C is a high affinity and selective PGD2 receptor agonist .

HY-130013

*HKYellow-AM (6/12-mixture)*	Fluorescent Dye	Others
HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .

HY-132637S

*Chlorfenvinphos-d10(Mixture* of cis-trans isomers)**	Isotope-Labeled Compounds	Others
Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-N6013

*Aloin(mixture* of A&B)**	MMP Bacterial Fungal	Infection Inflammation/Immunology Cancer
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; Hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W018772R

*D-Ribose(mixture* of isomers) (Standard)**	Endogenous Metabolite	Inflammation/Immunology Cancer
D-Ribose(mixture of isomers) (Standard) is the analytical standard of D-Ribose(mixture of isomers). This product is intended for research and analytical applications. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-Hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-117058

LY243246 (6S)-DDATHF	Antifolate	Cancer
LY243246 ((6S)-DDATHF), the 6S diastereomer of DDATHF, is a potent competitive inhibitor of 5’-phosphoribosylglycinamide formyltransferase (GAR transformylase). 6R- and 6S-diastereomers of DDATHF are remarkably similar and equiactive antimetabolites inhibitory to de novo purine synthesis .

HY-131164

*Potassium clavulanate mixture* with silicon dioxide (1:1)**	Antibiotic	Infection
Potassium clavulanate mixture with silicon dioxide (1:1) is a powdered mixture of 1 part Potassium clavulanate to 1 part Silicon dioxide .

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-D2276

*Polyglyceryl-10 Laurate mixture-LB*	Biochemical Assay Reagents	Others
Polyglyceryl-10 Laurate mixture-LB is a biochemical reagent.

HY-D2275

*Polyglyceryl-10 Laurate mixture-Foam*	Biochemical Assay Reagents	Others
Polyglyceryl-10 Laurate mixture-Foam is a biochemical reagent.

HY-16478

Trifluridine/tipiracil hydrochloride mixture 1 Publications Verification TAS-102; FTD/TPI	Nucleoside Antimetabolite/Analog Thymidylate Synthase	Cancer
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. The composition of Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). Trifluridine/tipiracil hydrochloride mixture (TAS-102) shows the antitumor activity mainly via the inhibition of thymidylate synthase (TS) and incorporation into DNA .

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6013

*Aloin(mixture* of A&B)**	Infection Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Inflammation/Immunology Disease Research Fields	MMP Bacterial Fungal
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-W018772

*D-Ribose(mixture* of isomers)** 3 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-N2078

Yamogenin Neodiosgenin	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields Steroids	LXR
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-N8549A

5-Dihydrocortisone	Structural Classification Classification of Application Fields Cardiacglycosides Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
5-Dihydrocortisone is a 5-Dihydrocortisone with mixture of isomers. 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver

HY-13956R

Pioglitazone (Standard)	Human Gut Microbiota Metabolites Source classification Endogenous metabolite	PPAR Ferroptosis
Pioglitazone (Standard) is the analytical standard of Pioglitazone. This product is intended for research and analytical applications. Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC₅₀ of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research .

HY-N7265

Epi-galantamine	Alkaloids other families Source classification Plants	Cholinesterase (ChE)
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC₅₀ of 45.7 μM .

HY-W018772R

*D-Ribose(mixture* of isomers) (Standard)**	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
D-Ribose(mixture of isomers) (Standard) is the analytical standard of D-Ribose(mixture of isomers). This product is intended for research and analytical applications. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-131152

*Leucinostatin (mixture* of A&B)**	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Inflammation/Immunology Disease Research Fields Other Antibiotics	Antibiotic
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics .

HY-N2078R

Yamogenin (Standard)	Structural Classification other families Source classification Plants Steroids	LXR
Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

Cat. No.	Product Name	Chemical Structure

HY-13956S

Pioglitazone-d4
Pioglitazone-d₄ is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].

HY-132379S

Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers)
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-134670S

*α-Hydroxy* Metoprolol-d5 (Mixture of Diastereomers)**
α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].

HY-132676S

*Ramiprilat-d5 (Mixture* of Diastereomers)**
Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-W653769

*Deltamethrin-d5 (Mixture* of Diastereomers)**
Deltamethrin-d5 (Mixture of Diastereomers) is the deuterium labeled Deltamethrin (Mixture of Diastereomers) .

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-144145S

Hydroxy Pioglitazone (M-II)-d4
Hydroxy Pioglitazone (M-II)-d₄ is the deuterium labeled Hydroxy Pioglitazone (M-II)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)**
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-132382S

*β-Sitosterol-d7 (mixture* of diasteromers)**
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].

HY-W008216S

HMMNI-d3
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-13956A

*(R)-Pioglitazone-d1*
(R)-Pioglitazone-d1 ((R)-U 72107-d1) is a stabilized and deuterated R-enantiomer of pioglitazone, exhibiting pharmacological properties that are beneficial for NASH treatment, including modulation of mitochondrial function, non-steroidal anti-inflammatory effects, and glucose-lowering capabilities.

HY-13956S1

Pioglitazone-d4 (alkyl)
Pioglitazone-d₄ (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1][2].

HY-132468S

*Keto Pioglitazone-d4 (M-III-d4)*
Keto Pioglitazone-d4 (M-III-d4) is the deuterium labeled Keto Pioglitazone (M-III) .

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-132637S

*Chlorfenvinphos-d10(Mixture* of cis-trans isomers)**
Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-131543S

*22-Hydroxy* Mifepristone-d6**
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W018772S15

D-Ribose(mixture of isomers)-13C5

D-Ribose(mixture of isomers)- ¹³C₅ isomers)- ¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-132485S

*N-Methyl Pantoprazole-d3 (Mixture* of 1 and 3 isomers)**
N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers) is the deuterium labeled N-Methyl Pantoprazole (Mixture of 1 and 3 isomers) .

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-W021008S

*3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d2*
3-Hydroxy-4,5-dimethylfuran-2(5H)-one-d₂ is deuterated labeled 4-Ethyl-2-methoxyphenol.

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