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PT-179 is an orthogonal Thalidomide (HY-14658) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zincfinger (ZF) degron, and mediate the degradation of the tagged protein. For example, PT-179 binds to the ubiquitin ligase substrate receptor cereblon by forming a complex with SD40 and efficiently degrades proteins N- or C-terminally fused to SD40 or SD36 (DC50 for eGFP: 4.5 nM and 14.3 nM). PT-179 can be used to develop compact protein degradation tagging platforms .
ZNF207-IN-1 (compound C16) is a potent inhibitor of ZincFingerProtein 207 (ZNF207)， with IC50 values ranging from 0.5–2.5 μM for inhibiting sphere formation and 0.5–15 μM for cytotoxicity. ZNF207-IN-1 exhibites efficient permeability across the blood–brain barrier .
Cisd2 agonist 2 (compound 6) is a Cisd2 activator (EC50=191 nM), and Cisd2 levels are associated with non-alcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant in vivo toxicity in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout). Cisd2 (CDGSH iron sulfur domain 2) is a zincfingerprotein that is mainly localized in the endoplasmic reticulum or mitochondrial membrane. Cisd2 participates in mitochondrial function by forming homodimers containing two redox-active 2Fe-2S clusters .
YPC-22026 is a zinc-fingerprotein 143 (ZNF143) inhibitor with an IC50 value of 9.0 μM. YPC-22026 is a potent tumor regression inducer. YPC-22026 exhibits anti‐tumor activities .
The ZBTB17 protein is a multifunctional transcription factor that functions as a binding partner-based activator or repressor and a targeted regulator of cell cycle progression. It is essential for early lymphocyte development, preventing apoptosis and ensuring lineage commitment. ZBTB17 Protein, Human (His) is the recombinant human-derived ZBTB17 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZBTB17 Protein, Human (His) is 188 a.a., with molecular weight of ~18.0-26.0 kDa.
The ZBTB7B protein is a transcriptional regulator that determines the lineage commitment of T cell precursors, which is critical for the fate of CD4 and CD8 cells. Essential for CD4 commitment, its absence results in CD8 commitment. ZBTB7B Protein, Human (Sf9) is the recombinant human-derived ZBTB7B protein, expressed by Sf9 insect cells , with tag free. The total length of ZBTB7B Protein, Human (Sf9) is 538 a.a., .
GZF1, a transcriptional repressor, regulates gene expression by binding to the GZF1 responsive element (GRE) with the consensus sequence 5'-TGCGCN[TG][CA]TATA-3'. Its role includes potential regulation of VSX2/HOX10 expression, and it interacts with NCL, suggesting a molecular association that contributes to its transcriptional modulatory activities. GZF1 Protein, Human (Sf9) is the recombinant human-derived GZF1 protein, expressed by Sf9 insect cells , with tag free. The total length of GZF1 Protein, Human (Sf9) is 710 a.a., .
The ZBTB7B protein is a transcriptional regulator that determines the lineage commitment of T cell precursors, which is critical for the fate of CD4 and CD8 cells. Essential for CD4 commitment, its absence results in CD8 commitment. ZBTB7B Protein, Human (Sf9, His, Strep) is the recombinant human-derived ZBTB7B protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ZBTB7B Protein, Human (Sf9, His, Strep) is 538 a.a., .
The ZFAND5 protein is a key player in protein degradation by the ubiquitin-proteasome system and serves as a potential anchor for ubiquitinated proteins, promoting their proteasomal targeting. It regulates NF-kappa-B activation and apoptosis by inhibiting NF-kappa-B activation induced by various stimuli, including RIPK1 and TRAF6 overexpression. ZFAND5 Protein, Human (Sf9) is the recombinant human-derived ZFAND5 protein, expressed by Sf9 insect cells , with tag free. The total length of ZFAND5 Protein, Human (Sf9) is 212 a.a., .
The ZNF70 protein itself is a potential regulator of transcriptional processes, suggesting that it may play a role in shaping cellular function through gene expression control. Although the specific mechanisms and target genes affected by ZNF70 are not fully understood, its versatility in transcriptional regulation implies potential effects on a variety of cellular pathways. ZNF70 Protein, Human (His) is the recombinant human-derived ZNF70 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZNF70 Protein, Human (His) is 446 a.a., with molecular weight of ~60.0 kDa.
ZMYND19 Protein, implicated in GPR24/MCH-R1 signaling, suggests a role in modulating the associated pathways. Its interaction with GPR24/MCH-R1 indicates regulatory involvement. Mechanisms and downstream effects of ZMYND19 in GPR24/MCH-R1 signaling require further elucidation. Exploring ZMYND19's functions may provide insights into its role in cellular responses, offering potential interventions in G protein-coupled receptor pathways. ZMYND19 Protein, Human (His) is the recombinant human-derived ZMYND19 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZMYND19 Protein, Human (His) is 227 a.a., with molecular weight of ~32.0 kDa.
GZF1, a transcriptional repressor, regulates gene expression by binding to the GZF1 responsive element (GRE) with the consensus sequence 5'-TGCGCN[TG][CA]TATA-3'. Its role includes potential regulation of VSX2/HOX10 expression, and it interacts with NCL, suggesting a molecular association that contributes to its transcriptional modulatory activities. GZF1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived GZF1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of GZF1 Protein, Human (Sf9, His, Strep) is 710 a.a., .
The ZFAND5 protein is a key player in protein degradation by the ubiquitin-proteasome system and serves as a potential anchor for ubiquitinated proteins, promoting their proteasomal targeting. It regulates NF-kappa-B activation and apoptosis by inhibiting NF-kappa-B activation induced by various stimuli, including RIPK1 and TRAF6 overexpression. ZFAND5 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ZFAND5 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ZFAND5 Protein, Human (Sf9, His, Strep) is 212 a.a., .
RIZ1 Protein, an S-adenosyl-L-methionine-dependent histone methyltransferase, specifically methylates 'Lys-9' of histone H3. Additionally, it acts as a DNA-binding transcription factor, showing affinity for the MTE within the HMOX1 gene. Implicated as a potential activator, RIZ1 suggests a regulatory role in HMOX1 gene expression beyond histone modification. RIZ1 Protein, Human is the recombinant human-derived RIZ1 protein, expressed by E. coli , with tag free. The total length of RIZ1 Protein, Human is 200 a.a., with molecular weight of ~26 kDa.
RIZ1 Protein, an S-adenosyl-L-methionine-dependent histone methyltransferase, specifically methylates 'Lys-9' of histone H3. Additionally, it acts as a DNA-binding transcription factor, showing affinity for the MTE within the HMOX1 gene. Implicated as a potential activator, RIZ1 suggests a regulatory role in HMOX1 gene expression beyond histone modification. RIZ1 Protein, Human (GST) is the recombinant human-derived RIZ1 protein, expressed by E. coli , with N-GST labeled tag. The total length of RIZ1 Protein, Human (GST) is 200 a.a., with molecular weight of ~49.6 kDa.
RIZ1 Protein, an S-adenosyl-L-methionine-dependent histone methyltransferase, specifically methylates 'Lys-9' of histone H3. Additionally, it acts as a DNA-binding transcription factor, showing affinity for the MTE within the HMOX1 gene. Implicated as a potential activator, RIZ1 suggests a regulatory role in HMOX1 gene expression beyond histone modification. RIZ1 Protein, Human (His) is the recombinant human-derived RIZ1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RIZ1 Protein, Human (His) is 200 a.a., with molecular weight of ~27 kDa.
The RNF141 protein emerged as a potential player in spermatogenesis, suggesting a role in male germ cell development. This implication highlights its importance in the complex regulatory networks that control reproductive biology. RNF141 Protein, Human is the recombinant human-derived RNF141 protein, expressed by E. coli , with tag free. The total length of RNF141 Protein, Human is 229 a.a., .
The OTUD7B protein acts as a negative regulator to inhibit the non-canonical NF-kappa-B pathway by deubiquitinating TRAF3, thereby inhibiting B cell responses. It prevents degradation of “Lys-48”-linked polyubiquitin chains on TRAF3 during atypical NF-kappa-B stimulation, avoiding overactivation of the pathway and affecting mucosal immunity. OTUD7B Protein, Human (Sf9) is the recombinant human-derived OTUD7B protein, expressed by Sf9 insect cells , with tag free. The total length of OTUD7B Protein, Human (Sf9) is 842 a.a., .
The OTUD7B protein acts as a negative regulator to inhibit the non-canonical NF-kappa-B pathway by deubiquitinating TRAF3, thereby inhibiting B cell responses. It prevents degradation of “Lys-48”-linked polyubiquitin chains on TRAF3 during atypical NF-kappa-B stimulation, avoiding overactivation of the pathway and affecting mucosal immunity. OTUD7B Protein, Human (Sf9, His, Strep) is the recombinant human-derived OTUD7B protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of OTUD7B Protein, Human (Sf9, His, Strep) is 842 a.a., .
The RNF141 protein emerged as a potential player in spermatogenesis, suggesting a role in male germ cell development. This implication highlights its importance in the complex regulatory networks that control reproductive biology. RNF141 Protein, Human (His) is the recombinant human-derived RNF141 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF141 Protein, Human (His) is 229 a.a., .
The ZNF100 protein emerged as a potential regulator of transcriptional processes, suggesting that it may influence cellular function through gene expression control. Although the specific mechanisms and target genes are not fully understood, the multifunctional nature of ZNF100 in the field of transcriptional regulation suggests its potential impact on various cellular pathways. ZNF100 Protein, Human (His) is the recombinant human-derived ZNF100 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZNF100 Protein, Human (His) is 108 a.a., with molecular weight of ~15.0 kDa.
The RNF114 protein is an E3 ubiquitin protein ligase that critically regulates a variety of cellular processes by ubiquitinating various substrates. RNF114 is involved in cell cycle progression, apoptosis, osteoclastogenesis and immunity, serving as a negative regulator of NF-kappa-B-dependent transcription, affecting immune responses by ubiquitinating TNFAIP3 and potentially TRAF6. RNF114 Protein, Human is the recombinant human-derived RNF114 protein, expressed by E. coli , with tag free. The total length of RNF114 Protein, Human is 227 a.a., .
The RNF114 protein is an E3 ubiquitin protein ligase that critically regulates a variety of cellular processes by ubiquitinating various substrates. RNF114 is involved in cell cycle progression, apoptosis, osteoclastogenesis and immunity, serving as a negative regulator of NF-kappa-B-dependent transcription, affecting immune responses by ubiquitinating TNFAIP3 and potentially TRAF6. RNF114 Protein, Human (GST) is the recombinant human-derived RNF114 protein, expressed by E. coli , with N-GST labeled tag. The total length of RNF114 Protein, Human (GST) is 227 a.a., .
The ZNF75A protein appears to be a potential influencer of transcriptional regulation, suggesting that it may play a role in shaping cellular function through gene expression control. Although the specific mechanisms and target genes affected by ZNF75A are not fully understood, its multifunctional nature in transcriptional regulation implies potential effects on a variety of cellular pathways. ZNF75A Protein, Human (His) is the recombinant human-derived ZNF75A protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZNF75A Protein, Human (His) is 105 a.a., with molecular weight of ~14.0 kDa.
The RING finger (RNF) protein contains the RING domain, and exerts E3 ubiquitin ligase that mediates the covalent attachment of ubiquitin to target proteins. RNF113B belongs to the RNF protein family. RNF113B Protein, Human is the recombinant human-derived RNF113B protein, expressed by E. coli , with tag free. The total length of RNF113B Protein, Human is 321 a.a., .
KIAA0136; Microrchidia 3; MORC family CW type ZincFinger 3; MORC family CW type ZincFingerProtein 3; MORC family CW-type ZincFingerProtein 3; MORC3; MORC3_HUMAN; Nuclear matrix Protein 2; Nuclear matrix Protein NXP2; NXP2; ZCW5; ZCWCC3
MORC3 protein is a nuclear matrix protein that forms MORC3-NB through an ATP-dependent mechanism to restrict viruses through IFN response regulation, which is critical for innate immunity.It regulates IFNB1 activation and has secondary IFN inhibitory functions.MORC3 Protein, Human (His-SUMO) is the recombinant human-derived MORC3 protein, expressed by E.coli , with N-His, N-SUMO labeled tag.
The RING finger (RNF) protein contains the RING domain, and exerts E3 ubiquitin ligase that mediates the covalent attachment of ubiquitin to target proteins. RNF113B belongs to the RNF protein family. RNF113B Protein, Human (His) is the recombinant human-derived RNF113B protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF113B Protein, Human (His) is 321 a.a., .
ZBTB9 Protein appears as a potential regulator in transcriptional processes, implying a role in modulating cellular functions through gene expression regulation. While specific targets and mechanisms are yet to be fully understood, ZBTB9's versatile nature suggests its potential impact on diverse cellular pathways. This makes ZBTB9 an intriguing candidate for further exploration in the realm of gene regulation and cellular homeostasis. ZBTB9 Protein, Human (His) is the recombinant human-derived ZBTB9 protein, expressed by E. coli , with C-6*His labeled tag. The total length of ZBTB9 Protein, Human (His) is 473 a.a., with molecular weight of ~60.0 kDa.
RNF113A is an important spliceosome component that participates in pre-mRNA splicing and contributes to U12-type intron splicing within the small spliceosome. As an E3 ubiquitin protein ligase, it catalyzes the transfer of ubiquitin to target proteins. RNF113A Protein, Human is the recombinant human-derived RNF113A protein, expressed by E. coli , with tag free. The total length of RNF113A Protein, Human is 342 a.a., .
RNF113A is an important spliceosome component that participates in pre-mRNA splicing and contributes to U12-type intron splicing within the small spliceosome. As an E3 ubiquitin protein ligase, it catalyzes the transfer of ubiquitin to target proteins. RNF113A Protein, Human (His) is the recombinant human-derived RNF113A protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF113A Protein, Human (His) is 342 a.a., .
ZFAND3 is a transcriptional regulatory protein that regulates the expression of adhesion and invasion related genes, and can drive the invasion of glioblastoma. In addition, ZFAND3 can improve glucose tolerance by improving insulin resistance and inhibiting gluconeogenesis, and is identified as a susceptibility gene for type 2 diabetes. ZFAND3 Protein, Human (Sf9) is the recombinant human-derived ZFAND3 protein, expressed by Sf9 insect cells , with tag free. The total length of ZFAND3 Protein, Human (Sf9) is 226 a.a., .
HKR3 Protein, Human (His, Strep) is the recombinant human-derived HKR3, expressed by E. coli , with Strep, His labeled tag. The total length of HKR3 Protein, Human (His, Strep) is 119 a.a.,
CTCF protein is a chromatin-binding factor that plays multiple roles in transcriptional regulation and epigenetic control. It binds to DNA at specific sites and acts as a transcriptional repressor by binding to chromatin insulators to prevent undesirable interactions between promoters and neighboring enhancers or silencers. CTCF Protein, Human is the recombinant human-derived CTCF protein, expressed by E. coli , with tag free.
ZNRF3, as an E3 ubiquitin protein ligase, plays a crucial role as a negative regulator in the Wnt signaling pathway. It does this by mediating the ubiquitination and subsequent degradation of components within the Wnt receptor complex, namely Frizzled and LRP6. ZNRF3 Protein, Human (HEK293, His) is the recombinant human-derived ZNRF3 protein, expressed by HEK293 , with C-6*His labeled tag.
UHRF2; E3 ubiquitin-Protein ligase UHRF2; Np95/ICBP90-like RING FingerProtein; Np95-like RING FingerProtein; Nuclear Protein 97; Nuclear ZincFingerProtein Np97; RING FingerProtein 107; RING-type E3 ubiquitin transferase UHRF2; Ubiquitin-like PHD and RING Finger domain-containing Protein 2; Ubiquitin-like-containing PHD and RING Finger domains Protein 2
UHRF2 protein is an E3 ubiquitin ligase involved in DNA methylation, histone modification, cell cycle regulation and DNA repair. UHRF2 Protein, Human (His, SUMO) is the recombinant human-derived UHRF2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of UHRF2 Protein, Human (His, SUMO) is 230 a.a., .
ZNRF2 protein is an E3 ubiquitin protein ligase that plays a crucial role in neuronal transmission and plasticity. It ubiquitinates Na(+)/K(+) ATPase α-1 subunit/ATP1A1, affecting its endocytosis or degradation, which is critical for neuronal function. ZNRF2 Protein, Human is the recombinant human-derived ZNRF2 protein, expressed by E. coli , with tag free. The total length of ZNRF2 Protein, Human is 241 a.a., .
ZNRF2 protein is an E3 ubiquitin protein ligase that plays a crucial role in neuronal transmission and plasticity. It ubiquitinates Na(+)/K(+) ATPase α-1 subunit/ATP1A1, affecting its endocytosis or degradation, which is critical for neuronal function. ZNRF2 Protein, Human (His) is the recombinant human-derived ZNRF2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZNRF2 Protein, Human (His) is 241 a.a., .
ZFAND3 is a transcriptional regulatory protein that regulates the expression of adhesion and invasion related genes, and can drive the invasion of glioblastoma. In addition, ZFAND3 can improve glucose tolerance by improving insulin resistance and inhibiting gluconeogenesis, and is identified as a susceptibility gene for type 2 diabetes. ZFAND3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ZFAND3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ZFAND3 Protein, Human (Sf9, His, Strep) is 226 a.a., .
ZNHIT1 is a key chromatin remodeling protein that regulates gene expression by promoting the incorporation of histone variants H2AZ1/H2A.Z. In muscle differentiation, ZNHIT1 is recruited to the MYOG promoter, mediating H2AZ1 binding and inducing muscle-specific gene expression. ZNHIT1 Protein, Human (His) is the recombinant human-derived ZNHIT1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of ZNHIT1 Protein, Human (His) is 154 a.a., with molecular weight of ~21.0 kDa.
ZRANB1 is a ubiquitin thioesterase that specifically hydrolyzes “Lys-29”-linked and “Lys-33”-linked diubiquitins, with additional activity on “Lys-63”-linked chains. It positively regulates the Wnt pathway by deubiquitinating APC, an inhibitor of Wnt-mediated transcription. ZRANB1 Protein, Human (Sf9) is the recombinant human-derived ZRANB1 protein, expressed by Sf9 insect cells , with tag free. The total length of ZRANB1 Protein, Human (Sf9) is 708 a.a., .
ZRANB1 is a ubiquitin thioesterase that specifically hydrolyzes “Lys-29”-linked and “Lys-33”-linked diubiquitins, with additional activity on “Lys-63”-linked chains. It positively regulates the Wnt pathway by deubiquitinating APC, an inhibitor of Wnt-mediated transcription. ZRANB1 Protein, Human (Sf9, His) is the recombinant human-derived ZRANB1 protein, expressed by Sf9 insect cells , with C-8*His labeled tag. The total length of ZRANB1 Protein, Human (Sf9, His) is 708 a.a., .
As an E3-type SUMO ligase, ZBED1 protein catalyzes CHD3/Mi2-α sumoylation, relieves transcriptional repression and promotes the recruitment of RNA polymerase II to gene promoters. This positively regulates H1-5, RPS6, RPL10A and RPL12 transcription, enhancing cell proliferation and growth. ZBED1 Protein, Human (His) is the recombinant human-derived ZBED1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of ZBED1 Protein, Human (His) is 98 a.a., with molecular weight of ~14.0 kDa.
The RNF216 protein accepts ubiquitin from specific enzymes and transfers it to the substrate, promoting its ubiquitination. It has antiviral activity, inhibits TNF- and IL-1-mediated NF-kappa-B activation, and promotes TNF- and RIP-mediated apoptosis. RNF216 Protein, Human is the recombinant human-derived RNF216 protein, expressed by E. coli , with tag free. The total length of RNF216 Protein, Human is 865 a.a., .
The RNF216 protein accepts ubiquitin from specific enzymes and transfers it to the substrate, promoting its ubiquitination. It has antiviral activity, inhibits TNF- and IL-1-mediated NF-kappa-B activation, and promotes TNF- and RIP-mediated apoptosis. RNF216 Protein, Human (His) is the recombinant human-derived RNF216 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF216 Protein, Human (His) is 865 a.a., .
SWSAP1, an ATPase selectively activated by single-stranded DNA, is vital for homologous recombination repair (HRR). In addition to ATPase activity, SWSAP1 independently binds DNA. Teaming up with ZSWIM7, it forms a complex crucial for HRR, with mutual stabilization. SWSAP1 interacts with key HRR proteins—RAD51, RAD51B, RAD51C, RAD51D, and XRCC3—underscoring its role in facilitating homologous recombination repair processes. SWSAP1 Protein, Human (His) is the recombinant human-derived SWSAP1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SWSAP1 Protein, Human (His) is 229 a.a., with molecular weight of ~30.0 kDa.
ANKFY1 is a proposed Rab5 effector that critically participates in endosomal dynamics by binding to PI(3)P, promoting homotypic early endosomal fusion and participating in heterotypic fusion. It plays a crucial role in macropinocytosis, is dependent on Rab5-GTP, and is essential for the correct localization of activated tyrosine kinase receptors such as PDGFRB. ANKFY1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ANKFY1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ANKFY1 Protein, Human (Sf9, His, Strep) is 1168 a.a., .
The EGR1/ZNF225 protein is a multifunctional transcriptional regulator that binds to the EGR site in the promoter of target genes and is independent of cytosine methylation. It controls the transcription of multiple target genes, affecting responses to growth factors, DNA damage, and ischemia. EGR1/ZNF225 Protein, Human (His) is the recombinant human-derived EGR1/ZNF225 protein, expressed by E. coli , with N-6*His labeled tag. The total length of EGR1/ZNF225 Protein, Human (His) is 152 a.a., with molecular weight of ~20.0 kDa.
BCL6 is a key transcriptional repressor of germinal centers and regulates multiple biological functions and lineages. It forms a complex with corepressors and histone deacetylase, directly binds to 5'-TTCCTAGAA-3', and inhibits genes involved in differentiation, inflammation, apoptosis and cell cycle control in GC B cells. BCL6 Protein, Human is the recombinant human-derived BCL6 protein, expressed by E. coli , with tag free. The total length of BCL6 Protein, Human is 706 a.a., with molecular weight of 79.0 kDa.
RBCK1 is an E3 ubiquitin protein ligase that cooperates with specific E2 enzymes such as UBE2L3/UBCM4 to transfer ubiquitin to substrates. It acts as an E3 ligase that oxidizes IREB2, relying on heme and oxygen for IREB2 ubiquitination. RBCK1 Protein, Human is the recombinant human-derived RBCK1 protein, expressed by E. coli , with tag free. The total length of RBCK1 Protein, Human is 509 a.a., .
RBCK1 is an E3 ubiquitin protein ligase that cooperates with specific E2 enzymes such as UBE2L3/UBCM4 to transfer ubiquitin to substrates. It acts as an E3 ligase that oxidizes IREB2, relying on heme and oxygen for IREB2 ubiquitination. RBCK1 Protein, Human (His) is the recombinant human-derived RBCK1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RBCK1 Protein, Human (His) is 509 a.a., .
BCL6 is a key transcriptional repressor of germinal centers and regulates multiple biological functions and lineages. It forms a complex with corepressors and histone deacetylase, directly binds to 5'-TTCCTAGAA-3', and inhibits genes involved in differentiation, inflammation, apoptosis and cell cycle control in GC B cells. BCL6 Protein, Human (GST) is the recombinant human-derived BCL6 protein, expressed by E. coli , with N-GST labeled tag. The total length of BCL6 Protein, Human (GST) is 706 a.a., with molecular weight of ~105.5 kDa.
DHHC20 Protein, Human (Sf9) is the recombinant human-derived DHHC20, expressed by Sf9 insect cells , with tag Free labeled tag. The total length of DHHC20 Protein, Human (Sf9) is 365 a.a.,
CKBBP1; CKII beta binding Protein 1; CKII beta-binding Protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box Protein 2; RING FingerProtein 7; RING-box Protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; Sensitive to apoptosis gene; Sensitive to apoptosis gene Protein; Zinc RING FingerProtein SAG
CKBBP1; CKII beta binding Protein 1; CKII beta-binding Protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box Protein 2; RING FingerProtein 7; RING-box Protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; Sensitive to apoptosis gene; Sensitive to apoptosis gene Protein; Zinc RING FingerProtein SAG
CRIP1 Protein, Human (GST) is the recombinant human-derived CRIP1, expressed by E. coli , with N-GST labeled tag. The total length of CRIP1 Protein, Human (GST) is 77 a.a.,
CKBBP1; CKII beta binding Protein 1; CKII beta-binding Protein 1; Rbx 2; Rbx2; RBX2_HUMAN; Regulator of cullins 2; RING box Protein 2; RING FingerProtein 7; RING-box Protein 2; RNF 7; RNF7; ROC 2; ROC2; SAG; Sensitive to apoptosis gene; Sensitive to apoptosis gene Protein; Zinc RING FingerProtein SAG
The KDM2A protein is a histone demethylase targeting "Lys-36" of histone H3. It plays a key role in the histone code, especially the demethylation of dimethylated H3 "Lys-36". Methylation. In addition to histone demethylation, KDM2A also recognizes and binds phosphorylated proteins, promoting their ubiquitination and degradation. KDM2A Protein, Human is the recombinant human-derived KDM2A protein, expressed by E. coli , with tag free. The total length of KDM2A Protein, Human is 115 a.a., .
The KDM2A protein is a histone demethylase targeting "Lys-36" of histone H3. It plays a key role in the histone code, especially the demethylation of dimethylated H3 "Lys-36". Methylation. In addition to histone demethylation, KDM2A also recognizes and binds phosphorylated proteins, promoting their ubiquitination and degradation. KDM2A Protein, Human (His) is the recombinant human-derived KDM2A protein, expressed by E. coli , with N-6*His labeled tag. The total length of KDM2A Protein, Human (His) is 115 a.a., .
Sall4 Antibody (YA1899) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1899), targeting Sall4, with a predicted molecular weight of 112 kDa (observed band size: 112 kDa). Sall4 Antibody (YA1899) can be used for WB, IHC-P experiment in human background.
ZincFinger BED domain containing 4; ZincFinger BED domain containing Protein 4; ZincFinger BED type containing 4; ZBED4_HUMAN.
WB
Human
ZBED4 Antibody is a rabbit-derived non-conjugated IgG antibody , targeting ZBED4 Antibody , with a predicted molecular weight of 130 kDa (observed band size:135 kDa). ZBED4 Antibody can be used for WB experiment in human background.
Endothelial Kruppel like ZincFingerProtein; Epithelial ZincFingerProtein EZF; EZF; GKLF; Gut-enriched krueppel-like factor; KLF; KLF4; KLF4_HUMAN; Krueppel-like factor 4; Kruppel like factor 4; Epithelial ZincFingerProtein EZF; Gut enriched Krueppel
WB
Human, Mouse, Rat
KLF4 Antibody (YA716) is a non-conjugated and Mouse origined monoclonal antibody about 55 kDa, targeting to KLF4 (3B3). It can be used for WB assays with tag free, in the background of Transfected.
RNF8 Antibody (YA1344) is a non-conjugated IgG antibody, targeting RNF8, with a predicted molecular weight of 56 kDa (observed band size: 60 kDa). RNF8 Antibody (YA1344) can be used for WB experiment in human, rat background.
ZNF160 Antibody (YA2453) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2453), targeting ZNF160, with a predicted molecular weight of 94 kDa (observed band size: 74 kDa). ZNF160 Antibody (YA2453) can be used for WB, IP experiment in human, mouse, rat background.
IKZF3; ZNFN1A3; ZincFingerProtein Aiolos; Ikaros family ZincFingerProtein 3
WB, IHC-P, ICC/IF, FC
Human, Mouse, Rat
IKZF3 Antibody (YA2116) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2116), targeting IKZF3, with a predicted molecular weight of 58 kDa (observed band size: 70 kDa). IKZF3 Antibody (YA2116) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
ZIC; Zic Protein member 1; ZincFingerProtein 201; ZincFingerProtein ZIC1; ZNF201
WB, ICC/IF, FC
Human, Mouse, Rat
ZIC 1 Antibody (YA3372) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3372), targeting ZIC 1, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). ZIC 1 Antibody (YA3372) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.
Ikaros Antibody (YA987) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA987), targeting Ikaros, with a predicted molecular weight of 58 kDa (observed band size: 58 kDa). Ikaros Antibody (YA987) can be used for WB, IP experiment in human background.
Ikaros Antibody (YA988) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA988), targeting Ikaros. Ikaros Antibody (YA988) can be used for IHC-P experiment in human background.
Gli 1; Gli1; Gli-1; GLI; GLI Kruppel family member 1; Glioma associated oncogene; Glioma associated oncogene homolog 1 (ZincFingerProtein); Oncogene GLI; Zfp 5; Zfp5; ZincFingerProtein GLI 1; ZincFingerProtein GLI1; GLI1_HUMAN.
WB, IHC-P, FC
Human, Mouse, Rat
Gli1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 118 kDa, targeting to Gli1. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.
AFP regulator 1; ZincFinger and homeodomain Protein 2
WB, ICC/IF
Human, Rat
ZHX2 Antibody (YA1746) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1746), targeting ZHX2, with a predicted molecular weight of 92 kDa (observed band size: 110 kDa). ZHX2 Antibody (YA1746) can be used for WB, ICC/IF experiment in human, rat background.
CTCF Antibody (YA2570) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2570), targeting CTCF, with a predicted molecular weight of 83 kDa (observed band size: 140 kDa). CTCF Antibody (YA2570) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.
ZNF364 Antibody (YA1579) is a non-conjugated IgG antibody, targeting ZNF364, with a predicted molecular weight of 34 kDa (observed band size: 34 kDa). ZNF364 Antibody (YA1579) can be used for WB experiment in human, rat background.
BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 Protein; BCL-6; B-cell lymphoma 5 Protein; BCL-5; Protein LAZ-3; ZincFinger and BTB domain-containing Protein 27; ZincFingerProtein 51
IHC-P
Human
Bcl6 Antibody (YA1281) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1281), targeting Bcl6. Bcl6 Antibody (YA1281) can be used for IHC-P experiment in human background.
ZEB1 Antibody (YA1153) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1153), targeting ZEB1. ZEB1 Antibody (YA1153) can be used for IHC-P experiment in human background.
TRIM25 Antibody (YA2278) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2278), targeting TRIM25, with a predicted molecular weight of 71 kDa (observed band size: 71 kDa). TRIM25 Antibody (YA2278) can be used for WB, ICC/IF, IP experiment in human, rat background.
ZNRF2 Antibody (YA3191) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3191), targeting ZNRF2, with a predicted molecular weight of 24 kDa (observed band size: 24 kDa). ZNRF2 Antibody (YA3191) can be used for WB, IHC-P experiment in human, mouse, rat background.
RCHY1; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; RING Finger and CHY ZincFinger domain-containing Protein 1; Androgen receptor N-terminal-interacting Protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-Protein ligase Pirh2; RING Finger
WB
Human
Pirh2 Antibody (YA1743) is a non-conjugated IgG antibody, targeting Pirh2, with a predicted molecular weight of 30 kDa (observed band size: 30 kDa). Pirh2 Antibody (YA1743) can be used for WB experiment in human background.
EGR2; KROX20; E3 SUMO-Protein ligase EGR2; AT591; E3 SUMO-Protein transferase ERG2 Curated; Early growth response Protein 2 (EGR-2); ZincFingerProtein Krox-20;
WB
Human, Mouse, Rat
EGR2 Antibody (YA1926) is a non-conjugated IgG antibody, targeting EGR2, with a predicted molecular weight of 50 kDa (observed band size: 53 kDa). EGR2 Antibody (YA1926) can be used for WB experiment in human, mouse, rat background.
DBF4; ASK; DBF4A; ZDBF1; Protein DBF4 homolog A; Activator of S phase kinase; Chiffon homolog A; DBF4-type ZincFinger-containing Protein 1
WB
Human
DBF4 Antibody (YA2652) is a non-conjugated IgG antibody, targeting DBF4, with a predicted molecular weight of 77 kDa (observed band size: 77 kDa). DBF4 Antibody (YA2652) can be used for WB experiment in human background.
TNFAIP3; OTUD7C; Tumor necrosis factor alpha-induced Protein 3; TNF alpha-induced Protein 3; OTU domain-containing Protein 7C; Putative DNA-binding Protein A20; ZincFingerProtein A20
WB, IHC-F, IHC-P, ICC/IF
Human
TNFAIP3 Antibody (YA2231) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2231), targeting TNFAIP3, with a predicted molecular weight of 90 kDa (observed band size: 82 kDa). TNFAIP3 Antibody (YA2231) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.
CHD3 Antibody (YA944) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA944), targeting CHD3, with a predicted molecular weight of 227 kDa (observed band size: 260 kDa). CHD3 Antibody (YA944) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
CHD3 Antibody (YA945) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA945), targeting CHD3, with a predicted molecular weight of 227 kDa (observed band size: 260 kDa). CHD3 Antibody (YA945) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
SNAI1_HUMAN; ZincFingerProtein SNAI1; SNAI1; SNAH; SNAI 1; SNA; SNAIL1; dJ710H13.1; Protein snail homolog 1 (Protein sna); Protein snail homolog 1; Protein sna
WB, IHC-P, ICC/IF, ELISA
Human, Mouse
SNAI1 Antibody is an unconjugated, approximately 29 kDa, rabbit-derived, anti-SNAI1 polyclonal antibody. SNAI1 Antibody can be used for: WB,IHC-P,ICC/IF,ELISA expriments in human,and mouse background without labeling.
CSDD1; FLJ12457; LIN 28; Lin-28A; LIN28; LIN28A; LN28A_HUMAN; Protein lin-28 homolog A; ZCCHC1; ZincFinger CCHC domain-containing Protein 1.
WB
Human, Mouse
LIN28A Antibody (YA711) is a non-conjugated and Mouse origined monoclonal antibody about 23 kDa, targeting to LIN28A (2C1). It can be used for WB assays with tag free, in the background of Human, Mouse.
SP7/Osterix Antibody is an unconjugated, approximately 45 kDa, rabbit-derived, anti-SP7/Osterix monoclonal antibody. SP7/Osterix Antibody can be used for: WB, IHC-P, IF-Tissue, IHC-Fr expriments in human, mouse, and rat background without labeling.
PRDM1/Blimp1 Antibody (YA1101) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1101), targeting PRDM1/Blimp1. PRDM1/Blimp1 Antibody (YA1101) can be used for IHC-P experiment in human background.
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