Search Result
Results for "
chelating agent
" in MedChemExpress (MCE) Product Catalog:
22
Biochemical Assay Reagents
3
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W008585
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- HY-126565
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Others
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Others
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Licam-C is a promising radiological decontaminant agent. Acting as a chelating agent, LICAM-C forms stable complexes with radioactive elements such as Plutonium (Pu) and Americium (Am). Licam-C is employed in research addressing the remediation of radioactive nucleotide contamination .
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- HY-136952
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Biochemical Assay Reagents
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Others
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p-SCN-Bn-HOPO is a bifunctional chelating agent. p-SCN-Bn-HOPO is used to bind to the radioactive isotope zirconium-89 (^89Zr) for use in ImmunoPET .
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- HY-W019885A
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Sodium triphosphate pentabasic, 98%
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Biochemical Assay Reagents
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Others
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Sodium tripolyphosphate (STPP), 98% is a biochemical reagent that can be used as pH adjustment, chelating agent, and detergent additive .
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- HY-D0223
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1-Pyridylazo-2-naphthol
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Biochemical Assay Reagents
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Others
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1-(2-Pyridylazo)-2-naphthol (1-Pyridylazo-2-naphthol) is an azo compound. 1-(2-Pyridylazo)-2-naphthol can be used as a chelating precipitant, flocculant, auxiliary complexing agent, and as a ligand for anchoring on other supports with the purpose of introducing
chelating property .
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- HY-153551
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Others
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Others
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HBED-CC-tris(tert-butyl ester), a HBED-CC derivative, is a bifunctional chelating agent. HBED-CC-tris(tert-butyl ester) is used in agricultural research and radiopharmacy .
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- HY-153551A
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Others
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Others
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HBED-CC-tris(tert-butyl ester) TFA, a HBED-CC derivative, is a bifunctional chelating agent. HBED-CC-tris(tert-butyl ester) is used in agricultural research and radiopharmacy .
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- HY-W019885
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Sodium triphosphate pentabasic, 85%
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Biochemical Assay Reagents
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Others
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Sodium tripolyphosphate (STPP), 85% (Sodium triphosphate pentabasic, 85%) is a biochemical reagent that can be used as pH adjustment, chelating agent, and detergent additive .
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- HY-121075
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Reverse Transcriptase
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Infection
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Alizarin complexone is a calcium-tracer and a chelating agent. Alizarin complexone is Rous-associated virus 2 reverse transcriptase (RAV-2 RT) inhibitor .
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- HY-W012683
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Others
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Cancer
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Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals . Iminodiacetic acid can be used for removal of toxic metal ions from water . Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) .
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- HY-N0420
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Wormwood acid
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Endogenous Metabolite
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Neurological Disease
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Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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- HY-W015410
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Endogenous Metabolite
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Inflammation/Immunology
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Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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- HY-153552A
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FAP
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Cancer
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NH2-UAMC1110 TFA is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activation protein (FAP) inhibitor. FAPI-QS is a chelating agent that can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors .
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- HY-W105700
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EDTA sodium hydrate
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Biochemical Assay Reagents
Bacterial
SOD
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Cardiovascular Disease
Neurological Disease
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Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid sodium hydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research .
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- HY-B1009
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EDTA trisodium salt; Trisodium EDTA
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Ferroptosis
Bacterial
SOD
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Cardiovascular Disease
Neurological Disease
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Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
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- HY-Y0682B
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EDTA tetrasodium
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Biochemical Assay Reagents
Bacterial
SOD
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Cardiovascular Disease
Neurological Disease
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Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .
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- HY-Y0682A
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EDTA disodium dihydrate
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Biochemical Assay Reagents
Bacterial
SOD
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Cardiovascular Disease
Neurological Disease
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Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
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- HY-Y0682
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EDTA
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Biochemical Assay Reagents
Bacterial
SOD
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Cardiovascular Disease
Neurological Disease
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Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
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- HY-16564
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- HY-158820
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QPI-1007
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Small Interfering RNA (siRNA)
Caspase
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Cardiovascular Disease
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Cosdosiran is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?
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- HY-158820A
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QPI-1007 sodium
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Small Interfering RNA (siRNA)
Caspase
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Cardiovascular Disease
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Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?
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- HY-E70364
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Biochemical Assay Reagents
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Inflammation/Immunology
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IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .
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- HY-122107
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TRODAT-1
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Others
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Others
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Tropantiol (TRODAT-1) is a chelating agent .
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- HY-122107A
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TRODAT-1 hydrochloride
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Others
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Others
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Tropantiol (TRODAT-1) hydrochloride is a chelating agent .
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- HY-B1768
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Dimercaptosuccinic acid; DMSA
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Others
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Others
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Succimer is a widely used chelating agent for the treatment of Pb poisoning.
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- HY-W127819
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- HY-114377
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Others
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Cancer
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p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor .
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- HY-139975
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Fluorescent Dye
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Cancer
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Antitumor agent-31 is a nanosized chelates of anchoring bisazo dye. Antitumor agent-31 can be used for an antioxidant and antitumor agent .
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- HY-148646
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Others
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Others
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p-NH2-CHX-A"-DTPA is a bifunctional chelating agent .
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- HY-W018746
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Ethylenediaminetetraacetic acid disodium
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Biochemical Assay Reagents
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Others
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EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
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- HY-100332
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Others
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Others
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CP 375 is a Fe 3+ chelating agent, with a log K1 value of 14.50.
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- HY-W009722A
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Ditiocarb sodium trihydrate, ACS, 99.0%
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HIV
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Infection
Cancer
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Sodium diethylcarbamodithioate trihydrate, ACS, 99.0% (Ditiocarb sodium trihydrate, ACS, 99.0%) is a copper reagent. The reaction with Cu 2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate, ACS, 99.0% can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer .
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- HY-13950
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Others
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Others
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S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.
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- HY-W030778
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Triglycollamic acid
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Others
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Others
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Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions .
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- HY-W004650
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Biochemical Assay Reagents
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Others
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TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .
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- HY-W102590
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Biochemical Assay Reagents
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Others
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DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-114758
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PIH
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Others
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Cancer
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Pyridoxal isonicotinoyl hydrazone (PIH) is a lipophilic, tridentate Fe-chelating agent that shows high Fe chelation efficacy .
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- HY-W007656
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Others
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Others
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Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .
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- HY-Y0308E
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Disodium hydrogen phosphate, for cell culture
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Biochemical Assay Reagents
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Others
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Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture can be used as an excipient, such as buffer, chelating agent, can used for cell culture .
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- HY-W134005
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Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate
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Biochemical Assay Reagents
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Others
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Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .
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- HY-W402032
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Biochemical Assay Reagents
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Others
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Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-N0151
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- HY-N0621
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Morin
5 Publications Verification
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Others
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Cancer
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Morin, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation .
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- HY-W013851
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Biochemical Assay Reagents
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Others
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EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper . EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils . EDTA-OH is able to cross brain-blood barrier .
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- HY-W581819
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Biochemical Assay Reagents
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Others
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Ferric glycinate is an iron amino acid chelate used as a food fortifier and therapeutic agent, which can prevent and ameliorate iron deficiency anemia .
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- HY-D0190
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HTTA; TTA; TTFA
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Mitochondrial Metabolism
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Infection
Others
Cancer
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2-Theoyltrifluoroacetone is a chelating agent and mitochondrial electron transfer chain inhibitor, with a IC50 value of 51.5 μM. 2-Thermoyltrifluoroacetone can chelate with various metal ions and has cytotoxicity and anti-tumor activity, which is expected to play an important role in the treatment of mitochondrial dysfunction related diseases [1][2][3].
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- HY-12691
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Others
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Cancer
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BFCAs-1 is a polyamino polycarboxylic bifunctional chelating agent(BFCAs); a broad range of applications in chemistry, biology and medicine and diagnostic imaging (MRI, SPECT, PET).
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- HY-W012037
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8-Quinolinol hemisulfate
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Bacterial
Antibiotic
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Infection
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8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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- HY-B0300S
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- HY-B0568S
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- HY-W030778R
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Triglycollamic acid (Standard)
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Others
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Others
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Nitrilotriacetic acid (Standard) is the analytical standard of Nitrilotriacetic acid. This product is intended for research and analytical applications. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions .
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- HY-W013178
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Biochemical Assay Reagents
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Others
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DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions .
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- HY-W030778S
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Isotope-Labeled Compounds
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Others
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Nitrilotriacetic acid-d9 is the deuterium labeled Nitrilotriacetic acid[1]. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[2].
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- HY-111605
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ADC Linker
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Cancer
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Macropa-NCS can be coupled with antibodies to form tumor-selective carrier molecules, which can be further combined with radionuclides as specific targeting cancer cell carriers, and is a linker-chelating agent in targeted alpha research (TAT) .
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- HY-W102714
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CDTA
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Others
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Metabolic Disease
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1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
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- HY-D1895
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Fluorescent Dye
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Others
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3,5-DiBr-PAESA is a supersensitive chelating agent that can be used for silver (I) determination in water in the case of absence of other interfering ions. 3,5-DiBr-PAESA can also be used for copper (II) determination .
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- HY-153552
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Others
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Cancer
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NH2-UAMC1110 is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors .
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- HY-W127847
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Triglycollamic acid trisodium salt
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Biochemical Assay Reagents
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Others
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Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.
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- HY-B0302
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Etidronate; HEDPA; HEDP
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Apoptosis
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Metabolic Disease
Cancer
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Etidronic acid (Etidronate) is an orally and intravenously active bisphosphonate. Etidronic acid inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid has anticancer activity. Etidronic acid is a chelating agent and can be used to remove heavy metal in water .
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- HY-B0302A
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Etidronate disodium; HEDPA disodium; HEDP disodium
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Apoptosis
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Metabolic Disease
Cancer
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Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water .
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- HY-W017457
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(±)-Penicillamine
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Others
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Others
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DL-Penicillamine [(±)-Penicillamine] is a copper chelating agent. DL-Penicillamine has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A). DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response .
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- HY-W034674
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Silver(1+) diethyldithiocarbamate
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Biochemical Assay Reagents
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Others
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Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
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- HY-W034576
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Hexaaza-18-crown-6 hexahydrochloride; 1,4,7,10,13,16-Hexaazacyclooctadecane hexahydrochloride
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Biochemical Assay Reagents
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Cancer
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Hexacyclen (Cycloalkene) is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. Hexacyclen is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions, and is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Hexacyclen also acts as an inhibitor of cancer .
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- HY-N10473
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Bacterial
Fungal
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Infection
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Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe 3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .
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- HY-158125
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PSMA
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Cancer
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PSMA binder-2 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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- HY-B0568
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Deferiprone
Maximum Cited Publications
37 Publications Verification
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Ferroptosis
HCV
Apoptosis
COX
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Infection
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
Endocrinology
Cancer
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Deferiprone is a potent, orally active, brain-penetrant, cell-penetrant, skin-permeable, free iron chelating agent. Deferiprone inhibits the proliferation and migration, and stimulates apoptosis in tumor cell. Deferiprone has antianemic, neuroprotective, anti-inflammatory, antioxidant, and antidotal activity. Deferiprone can be used in cancer, cardiovascular disease, infection, inflammation, and neurological disease study .
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- HY-W034566A
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Hexaaza-18-crown-6 trisulfate; 1,4,7,10,13,16-Hexaazacyclooctadecane trisulfate
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Biochemical Assay Reagents
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Others
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Hexacyclen, also known as cycloalkene, is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications.
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- HY-W017457R
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Others
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Others
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DL-Penicillamine (Standard) is the analytical standard of DL-Penicillamine. This product is intended for research and analytical applications. DL-Penicillamine [(±)-Penicillamine] is a copper chelating agent. DL-Penicillamine has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A). DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response .
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- HY-W115718
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Dopamine β-hydroxylase
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Neurological Disease
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Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) .
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- HY-158123
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PSMA
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Cancer
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PSMA binder-1 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or it can be labeled with 225Ac (to obtain Actinium-225-PSMA-Trillium (BAY 3563254)), which has a radioactive killing effect; it can be used as a Macropa chelator for targeted radionuclide therapy (TRT) , has a strong inhibitory effect on metastatic castration-resistant prostate cancer (mCRPC) .
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- HY-150563
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Monoamine Oxidase
Amyloid-β
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Neurological Disease
Inflammation/Immunology
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Neuroinflammatory-IN-2 is a potent anti-neuroinflammatory agent with an IC50 value of 10.30 μM for MAO-B, and 96.33% inhibition of Aβ1-42 aggregation at 25 μM. Neuroinflammatory-IN-2 has neuroprotective activity in H2O2-induced PC-12 cell injury. Neuroinflammatory-IN-2 also has biometal chelating abilities, antioxidant activity, anti-neuroinflammatory activity and appropriate BBB permeability. Neuroinflammatory-IN-2 can be used for researching Alzheimer’s disease .
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- HY-158122
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DNA-PK
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Cancer
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Lys(CO-C3-p-I-Ph)-O-tBu is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules. Lys(CO-C3-p-I-Ph)-O-tBu can increase the residence time of PSMA ligand in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-O-tBu also reduces salivary gland absorption, possibly extending the half-life of the active compound. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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- HY-158118
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DNA-PK
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Cancer
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Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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| Cat. No. |
Product Name |
Type |
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- HY-D1895
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Fluorescent Dyes/Probes
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3,5-DiBr-PAESA is a supersensitive chelating agent that can be used for silver (I) determination in water in the case of absence of other interfering ions. 3,5-DiBr-PAESA can also be used for copper (II) determination .
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| Cat. No. |
Product Name |
Type |
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- HY-W008585
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- HY-W105700
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EDTA sodium hydrate
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Biochemical Assay Reagents
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Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid sodium hydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid sodium hydrate can be used for coronary artery disease and neural system disease research .
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- HY-W019885A
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Sodium triphosphate pentabasic, 98%
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Buffer Reagents
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Sodium tripolyphosphate (STPP), 98% is a biochemical reagent that can be used as pH adjustment, chelating agent, and detergent additive .
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- HY-D0223
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1-Pyridylazo-2-naphthol
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Biochemical Assay Reagents
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1-(2-Pyridylazo)-2-naphthol (1-Pyridylazo-2-naphthol) is an azo compound. 1-(2-Pyridylazo)-2-naphthol can be used as a chelating precipitant, flocculant, auxiliary complexing agent, and as a ligand for anchoring on other supports with the purpose of introducing
chelating property .
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- HY-W019885
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Sodium triphosphate pentabasic, 85%
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Buffer Reagents
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Sodium tripolyphosphate (STPP), 85% (Sodium triphosphate pentabasic, 85%) is a biochemical reagent that can be used as pH adjustment, chelating agent, and detergent additive .
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- HY-Y0682B
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EDTA tetrasodium
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Biochemical Assay Reagents
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Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .
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- HY-Y0682A
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EDTA disodium dihydrate
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Biochemical Assay Reagents
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Ethylenediaminetetraacetic acid (EDTA) disodium dehydrate is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid disodium dehydrate has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid disodium dehydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid disodium dehydrate can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid disodium dehydrate can be used for coronary artery disease and neural system disease research .
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- HY-Y0682
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EDTA
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Chelators
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Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
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- HY-W127819
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- HY-W018746
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Ethylenediaminetetraacetic acid disodium
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Chelators
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EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
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- HY-W009722A
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Ditiocarb sodium trihydrate, ACS, 99.0%
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Chelators
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Sodium diethylcarbamodithioate trihydrate, ACS, 99.0% (Ditiocarb sodium trihydrate, ACS, 99.0%) is a copper reagent. The reaction with Cu 2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate, ACS, 99.0% can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer .
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- HY-W004650
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Chelators
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TETA hydrochloride hydrate is an effective selective chelating agent for copper (II). TETA hydrochloride hydrate can be used for drug coupling .
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-
- HY-W102590
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Chelators
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DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-Y0308E
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Disodium hydrogen phosphate, for cell culture
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Buffer Reagents
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Sodium phosphate dibasic (Disodium hydrogen phosphate), for cell culture can be used as an excipient, such as buffer, chelating agent, can used for cell culture .
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- HY-W134005
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Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate
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Chelators
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Mg(II)-EDTA (disodium tetrahydrate) is an ion-chelating agent that can be used to prepare reagents for ion-sensitive experiments .
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-
- HY-W402032
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Chelators
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Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .
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- HY-W013851
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Chelators
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EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper . EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils . EDTA-OH is able to cross brain-blood barrier .
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- HY-W013178
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Biochemical Assay Reagents
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DCTA monohydrate is an organic acid. DCTA refers to N,N,N',N' -tetraacetic acid, which has a strong chelating ability. DCTA monohydrate can be used as a chelating agent and coordination reagent for metal ions. DCTA monohydrate, for example, forms stable complexes with many metal ions, including calcium, magnesium and zinc. DCTA modified with ethylene glycol is selective to calcium ions in the presence of magnesium ions .
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- HY-W127847
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Triglycollamic acid trisodium salt
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Biochemical Assay Reagents
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Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.
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- HY-W034674
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Silver(1+) diethyldithiocarbamate
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Biochemical Assay Reagents
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Silver diethyldithiocarbamate (SDDC) is an organic compound consisting of silver ions complexed with the ligand diethyldithiocarbamate. SDDC is mainly used as a reagent in analytical chemistry to detect the presence of copper, iron and other heavy metals in various materials. It acts as a chelating agent, binding to metal ions and forming stable complexes that can be easily analyzed using techniques such as UV-Vis spectroscopy.
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- HY-W034576
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Hexaaza-18-crown-6 hexahydrochloride; 1,4,7,10,13,16-Hexaazacyclooctadecane hexahydrochloride
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Biochemical Assay Reagents
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Hexacyclen (Cycloalkene) is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. Hexacyclen is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions, and is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Hexacyclen also acts as an inhibitor of cancer .
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- HY-W034566A
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Hexaaza-18-crown-6 trisulfate; 1,4,7,10,13,16-Hexaazacyclooctadecane trisulfate
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Biochemical Assay Reagents
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Hexacyclen, also known as cycloalkene, is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications.
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P10012
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GYK-DTPA
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Peptides
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Cancer
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Pendetide is a chelating agent, can be conjugated with Indium (111In) Capromab for further diagnostic use. Capromab pendetide is a FDA-approved imaging agent for the detection of soft tissue metastases in prostate carcinoma .
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- HY-P10369
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Peptides
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Cardiovascular Disease
Inflammation/Immunology
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Betiatide, as a chelating agent for Technetium-99m ( 99mTc), is used to prepare 99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0300S
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Penicillamine-d3 is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
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- HY-B0568S
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Deferiprone-d3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating agent to be used therapeutically in conditions of transfusional iron overload[1][2].
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- HY-W030778S
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Nitrilotriacetic acid-d9 is the deuterium labeled Nitrilotriacetic acid[1]. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[2].
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