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Results for "

natural cytotoxicity

" in MedChemExpress (MCE) Product Catalog:

73

Inhibitors & Agonists

2

Peptides

6

Inhibitory Antibodies

55

Natural
Products

12

Recombinant Proteins

3

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N8088

    Others Cancer
    Neolancerin is a natural product with weak cytotoxic activity against HL-60 cells .
    Neolancerin
  • HY-160421

    Apoptosis Inflammation/Immunology Cancer
    TREM2-IN-1 (OPA) is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206 + and CX3CR1 + immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells .
    TREM2-IN-1
  • HY-156186

    Others Cancer
    Anticancer agent 160 (Compound 6) is a natural product derived from Parthenium hysterophorus. Anticancer agent 160 is cytotoxic to HCT-116 cells, IC50=5.0 μM .
    Anticancer agent 160
  • HY-122948

    Others Cancer
    Isogambogenic acid is a natural product that can be isolated from Resina Garciniae. Isogambogenic acid has cytotoxicity to cancer cell lines with IC50 values of 0.4327-5.942 μmol/L .
    Isogambogenic acid
  • HY-N8317

    Others Cancer
    Rubicordifolin is a natural product that can be isolated from Rubia cordifolia. Rubicordifolin inhibits the growth of sarcoma ascites in mice. Rubicordifolin has significant cytotoxic activity both in vitro and in vivo .
    Rubicordifolin
  • HY-N8915

    Others Others
    Deoxyflindissone (Compound 13) is a triterpenoid compound. Deoxyflindissone is isolated from natural Cornus walteri .Deoxyflindissone has significant cytotoxic activity .
    Deoxyflindissone
  • HY-N10363

    Others Cancer
    Pixinol, a natural glycoside, shows cytotoxicity against the human lung carcinoma GLC4 and adenocarcinoma COLO 320 cell lines (IC50=71 µM and 43 µM, respectively) .
    Pixinol
  • HY-136689

    Others Cancer
    Taxin B is a natural product with cytotoxicity effects .
    Taxin B
  • HY-N6582

    Others Cancer
    Flavokawin C is a natural compound with antioxidative and cytotoxicity .
    Flavokawin C
  • HY-N1155

    Others Cardiovascular Disease
    Theviridoside is a natural iridoid glucoside found in the leaves of Cerbera odollam, it has cytotoxicity.
    Theviridoside
  • HY-142007

    Others Others
    Epothilone D1 is an isolated natural product that shows cytotoxicity against mouse fibroblasts.
    Epothilone D1
  • HY-N3430

    AF33

    Others Cancer
    Kaempferol tetraacetate (AF33) is a natural product. Kaempferol tetraacetate shows cytotoxicity .
    Kaempferol tetraacetate
  • HY-133220

    Others Cancer
    Guajadial E is a natural product that can be found in Psidium guajava. Guajadial E shows cytotoxicity .
    Guajadial E
  • HY-133220A

    Others Cancer
    Guajadial F is a natural product that can be found in Psidium guajava. Guajadial F shows cytotoxicity .
    Guajadial F
  • HY-N7011

    Others Inflammation/Immunology
    Epicorynoxidine, a natural alkaloid, shows cytotoxic effects P-388 cell line with an ED50 of 25.53 μg/mL .
    Epicorynoxidine
  • HY-N1266

    Others Others
    Scutebata B (compound 4) is a neoclerodane diterpenoid iaolated from the whole plant of Scutellaria barbata. Scutebata B has cytotoxic activities with IC50 values of 10.27~28.48 μM .
    Scutebata B
  • HY-W010533

    Others Others
    (E)-2-Methyl-2-pentenoic acid is the component can be used to synthesize the cytotoxic natural product Lactimidomycin .
    (E)-2-Methyl-2-pentenoic acid
  • HY-N1081A

    (S)-Viteralone

    Others Cancer
    Viteralone (compound 5) is a natural product that can be isolated from Vitex negundo. Viteralone is cytotoxic to HL-60 cancer cells .
    Viteralone
  • HY-N12524

    Bacterial Infection Cancer
    Cyclo(prolyltyrosyl) is a natural compound that can be found in various microorganisms and marine sponges. Cyclo(prolyltyrosyl) has antibacterial, phytotoxic and cytotoxic properties .
    Cyclo(prolyltyrosyl)
  • HY-133223

    Others Cancer
    Hispidanin B is a natural product that can be extracted from the rhizomes of Isodon hispida. Hispidanin B has cytotoxic activities against cancer cells .
    Hispidanin B
  • HY-142102

    (+)-T988C

    Others Cancer
    T988C is a heptacyclic epidithiodioxopiperazine (ETP) natural product. T988C shows strong cytotoxicity to cultured P388 leukemia cells .
    T988C
  • HY-117371

    (-)-Hemiasterlin; Milnamide B

    ADC Cytotoxin Cancer
    Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .
    Hemiasterlin
  • HY-143242

    Others Others
    Phidianidine B is a highly cytotoxic 1,2,4-oxadiazole marine metabolite. Phidianidine B is a natural product that can be isolated from a marine mollusk .
    Phidianidine B
  • HY-N8679

    Endogenous Metabolite Cancer
    Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells .
    Physalin C
  • HY-N1318S

    Psathyrotin-d9

    Autophagy Neurological Disease Inflammation/Immunology Cancer
    Salvigenin-d9 is the deuterium labeled Salvigenin. Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].
    Salvigenin-d9
  • HY-N7933

    ALKANE C24

    Apoptosis Inflammation/Immunology
    Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer .
    Tetracosane
  • HY-N2852

    Others Others
    α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH .
    α-Terthienylmethanol
  • HY-N12192

    Others Others
    Ebenifoline E-II (Compound 2) is a sesquiterpene alkaloid derived from Euonymus laxiflorus. Ebenifoline E-II is cytotoxic .
    Ebenifoline E-II
  • HY-W024604

    4,4-Dimethylcyclopent-2-enone

    Others Cancer
    4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity .
    4,4-Dimethyl-2-cyclopenten-1-one
  • HY-N2445
    Flavokawain C
    1 Publications Verification

    Apoptosis Cancer
    Flavokawain C is a natural chalcone found in Kava root. Flavokawain C exerts cytotoxicity against human cancer cell lines, with an IC50 of 12.75 μM for HCT 116 cells .
    Flavokawain C
  • HY-N3916

    (+)-Galanolactone

    Fungal Infection
    Galanolactone is a natural product that can be isolated from the seeds of Alpinia galanga. Galanolactone shows antifungal activitie. Galanolactone shows cytotoxicity against KB cells with an EC50 of 38.5 µg/ml .
    Galanolactone
  • HY-129148

    GAAM1

    Others Cancer
    Ganoderic acid AM1 (GAAM1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid AM1 shows cytotoxicity with an IC50 value of 19.8 µM for HeLa cells .
    Ganoderic acid AM1
  • HY-N1912

    Others Cancer
    Andropanolide is a natural product that exerts cytotoxicity toward carcinoma cells and significantly inhibits the overproduction of nitric oxide (NO) in Lipopolysaccharides (HY-D1056) (LPS)-stimulated RAW264.7 macrophages .
    Andropanolide
  • HY-N8846

    Fungal Infection
    dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .
    dl-Aloesol
  • HY-N1318
    Salvigenin
    2 Publications Verification

    Psathyrotin

    Autophagy Apoptosis ROS Kinase Neurological Disease Inflammation/Immunology Cancer
    Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis .
    Salvigenin
  • HY-N3722

    Others Cancer
    O-Demethylmurrayanine is a natural phenol with anticancer effects. O-Demethylmurrayanine exhibits strong cytotoxicity against MCF-7 and SMMC-7721 with IC50 values in the range 4.42-7.59 μg/mL .
    O-Demethylmurrayanine
  • HY-N8739

    Endogenous Metabolite Cancer
    2-Hydroxyxanthone (Compound 3) is an isoprene flavone derived from Calophyllum inophyllum. 2-Hydroxyxanthone has an obvious killing effect on K562 cells .
    2-Hydroxyxanthone
  • HY-156089

    Others Inflammation/Immunology Cancer
    Triptoquinone H is a class of natural product isolated from traditional Chinese medicine Tripterygium hypoglaucu. Triptoquinone H has strong cytotoxic, immunomodulatory and anti-inflammatory activities. Triptoquinone H can be used for cancer or inflammatory diseases research .
    Triptoquinone H
  • HY-N12128

    Others Cancer
    Ophiopogonin R (compound 3) is a steroid saponin. Ophiopogonin R was isolated and purified from natural ophiopogonin. Ophiopogonin R was not cytotoxic to five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela) .
    Ophiopogonin R
  • HY-Y0790S

    p-Isopropylbenzaldehyde-d8

    Endogenous Metabolite Isotope-Labeled Compounds Cancer
    Cuminaldehyde-d8 is deuterated labeled Cuminaldehyde (HY-Y0790). Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity .
    Cuminaldehyde-d8
  • HY-Y0493

    HOOBt

    STAT HIV Infection Cancer
    HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer .
    HODHBt
  • HY-N3057

    Others Cancer
    Pinostrobin chalcone is found to be potent natural cytotoxic compounds against MDA-MB-231 and HT-29 colon cancer cell lines(IC50 = 20.42±2.23 and 22.51±0.42 μg/mL) .
    Pinostrobin chalcone
  • HY-N7933R

    Apoptosis Inflammation/Immunology
    Tetracosane (Standard) is the analytical standard of Tetracosane. This product is intended for research and analytical applications. Tetracosane (ALKANE C24) is a natural product that can be found in Acrostichum aureum. Tetracosane hows cytotoxicity and induces Apoptosis. Tetracosane has the potential for the research of peptic ulcer .
    Tetracosane (Standard)
  • HY-W015307S

    Biochemical Assay Reagents Isotope-Labeled Compounds Others
    4-Ethyloctanoic acid- 13C2 is 13C labeled Cuminaldehyde (HY-Y0790). Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity .
    4-Ethyloctanoic acid-13C2
  • HY-N0763
    Angelicin
    Maximum Cited Publications
    8 Publications Verification

    Isopsoralen

    Apoptosis Virus Protease Cancer
    Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).
    Angelicin
  • HY-P9977
    Amivantamab
    1 Publications Verification

    JNJ-61186372

    EGFR Cancer
    Amivantamab (JNJ-61186372) is a human EGFR-MET bispecific antibody with immune anticancer activity. Amivantamab inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells .
    Amivantamab
  • HY-N11519

    Others Cancer
    Polyporusterone C (Compound 3) is a natural product that can be isolated from Polyporus umbellatus. Polyporusterone C shows cytotoxic activities with IC50s of 37, 26 and 42 μg/mL against L-1210 cells at 3, 5 and 7 days, respectively .
    Polyporusterone C
  • HY-125098
    Illudin S
    1 Publications Verification

    DNA Alkylator/Crosslinker Apoptosis Infection Cancer
    Illudin S, a cytotoxic Illudin, is a natural sesquiterpene with strong anti-tumour and antiviral activities. Illudin S has genotoxic activities. Illudin S blocks the G1-S phase interface of the cell cycle in human leukemia cells .
    Illudin S
  • HY-N7173

    Parasite Infection
    7-Methoxy-β-carboline-1-propionic acid (compound 46) is a cytotoxic and antimalarial compound. 7-Methoxy-β-carboline-1-propionic acid can be extracted from the roots of Eurycoma longifolia .
    7-Methoxy-β-carboline-1-propionic acid
  • HY-N3966

    Others Others
    Goniodiol 8-acetate is a styrylpyrones that can be isolated from the leaves of Goniothalamus amuyon. Goniodiol 8-acetate has cytotoxic activity .
    Goniodiol 8-acetate

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