2,3-Butanediol

Name: 2,3-Butanediol
Brand: MedChemExpress
SKU: HY-128387
Rating: 4.5 (1 reviews)

Cat. No.: HY-128387 Purity: 99.87%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

2,3-Butanediol is a butanediol derived from the bioconversion of natural resources.

For research use only. We do not sell to patients.

2,3-Butanediol Chemical Structure

CAS No. : 513-85-9

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 35	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 35	In-stock	Estimated Time of Arrival: December 31
Liquid
50 mg	USD 32	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 2,3-Butanediol:

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Biological Activity
Purity & Documentation
References
Customer Review

Description

2,3-Butanediol is a butanediol derived from the bioconversion of natural resources^[1].

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

Molecular Weight

90.12

Formula

C₄H₁₀O₂

CAS No.

513-85-9

Appearance

Liquid (Density: 1.002 g/cm³)

Color

Colorless to light yellow

SMILES

CC(O)C(O)C

Structure Classification

Others

Initial Source

Microorganisms

Escherichia coli

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (1109.63 mM; Need ultrasonic)

DMSO : 100 mg/mL (1109.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	11.0963 mL	55.4816 mL	110.9632 mL
5 mM	2.2193 mL	11.0963 mL	22.1926 mL
10 mM	1.1096 mL	5.5482 mL	11.0963 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (27.74 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (27.74 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (27.74 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 140 mg/mL (1553.48 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.87%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (249 KB) HNMR (125 KB) GC (196 KB)

Handling Instructions (2659 KB)

References

[1]. Zhang L, et al. Mechanism of 2,3-butanediol stereoisomers formation in a newly isolated Serratia sp. T241. Sci Rep. 2016 Jan 12;6:19257. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	11.0963 mL	55.4816 mL	110.9632 mL	277.4079 mL
	5 mM	2.2193 mL	11.0963 mL	22.1926 mL	55.4816 mL
	10 mM	1.1096 mL	5.5482 mL	11.0963 mL	27.7408 mL
	15 mM	0.7398 mL	3.6988 mL	7.3975 mL	18.4939 mL
	20 mM	0.5548 mL	2.7741 mL	5.5482 mL	13.8704 mL
	25 mM	0.4439 mL	2.2193 mL	4.4385 mL	11.0963 mL
	30 mM	0.3699 mL	1.8494 mL	3.6988 mL	9.2469 mL
	40 mM	0.2774 mL	1.3870 mL	2.7741 mL	6.9352 mL
	50 mM	0.2219 mL	1.1096 mL	2.2193 mL	5.5482 mL
	60 mM	0.1849 mL	0.9247 mL	1.8494 mL	4.6235 mL
	80 mM	0.1387 mL	0.6935 mL	1.3870 mL	3.4676 mL
	100 mM	0.1110 mL	0.5548 mL	1.1096 mL	2.7741 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

2,3-Butanediol Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2,3-Butanediol513-85-9Endogenous MetaboliteInhibitorinhibitorinhibit

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2,3-Butanediol

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Other Forms of 2,3-Butanediol:

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References

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Complete Stock Solution Preparation Table

2,3-Butanediol Related Classifications

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