2. Gene
  3. KPRP - keratinocyte proline rich protein Gene

KPRP - keratinocyte proline rich protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C1orf45

Gene ID: 448834 | Gene type: protein coding

About KPRP

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:152,758,025-152,762,056 (from NCBI)

This gene has 1 transcript (splice variant), 142 orthologues and 12 paralogues. Restricted expression toward skin (RPKM 105.2).

Summary

This gene encodes a proline-rich skin protein possibly involved in keratinocyte differentiation. [provided by RefSeq, Jul 2016]

KPRP Products(1)

mRNA Protein Name
NM_001025231.3 NP_001020402.1 keratinocyte proline-rich protein
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27107012 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

keratinocyte proline-rich protein

keratinocyte expressed, proline-rich protein

KPRP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra KPRP Q5T749 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP4-2 Homo sapiens Q9BYR5
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP13-3 Homo sapiens Q3SY46
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP13-3 Homo sapiens Q3SY46
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 LCE3C Homo sapiens Q5T5A8
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 NID2 Homo sapiens Q8IV28
Validated Y2H
32296183
Intra KPRP Q5T749 DYRK1A Homo sapiens Q13627
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 DYRK1A Homo sapiens Q13627
Y2H Array
32296183
Intra KPRP Q5T749 ITIH6 Homo sapiens Q6UXX5
Y2H Array
32296183
Intra KPRP Q5T749 ITIH6 Homo sapiens Q6UXX5
Validated Y2H
32296183
Intra KPRP Q5T749 ITIH6 Homo sapiens Q6UXX5
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP1-5 Homo sapiens Q9BYS1
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP1-5 Homo sapiens Q9BYS1
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP1-3 Homo sapiens Q8IUG1
Y2H Array
32296183
Intra KPRP Q5T749 TFAP2D Homo sapiens Q7Z6R9
Y2H Array
32296183
Intra KPRP Q5T749 TFAP2D Homo sapiens Q7Z6R9
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 VGLL3 Homo sapiens A8MV65-2
Y2H Array
32296183
Intra KPRP Q5T749 VGLL3 Homo sapiens A8MV65-2
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 VWC2 Homo sapiens Q2TAL6
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 VWC2 Homo sapiens Q2TAL6
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP5-3 Homo sapiens Q6L8H2
Validated Y2H
32296183
Intra KPRP Q5T749 GNE Homo sapiens Q9Y223-2
Validated Y2H
32296183
Intra KPRP Q5T749 ACTMAP Homo sapiens Q5BKX5-3
Y2H Array
32296183
Intra KPRP Q5T749 ACTMAP Homo sapiens Q5BKX5-3
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Array
32296183
Intra KPRP Q5T749 GUCD1 Homo sapiens Q96NT3-2
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP5-7 Homo sapiens Q6L8G8
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP5-7 Homo sapiens Q6L8G8
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP4-5 Homo sapiens Q9BYR2
Validated Y2H
32296183
Intra KPRP Q5T749 SAXO4 Homo sapiens Q7Z5V6-2
Validated Y2H
32296183
Intra KPRP Q5T749 ATG9A Homo sapiens Q7Z3C6-3
Validated Y2H
32296183
Intra KPRP Q5T749 NUFIP2 Homo sapiens Q7Z417
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP6-1 Homo sapiens Q3LI64
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP6-1 Homo sapiens Q3LI64
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 ESR2 Homo sapiens Q92731-3
Validated Y2H
32296183
Intra KPRP Q5T749 SPRY3 Homo sapiens O43610
Y2H Array
32296183
Intra KPRP Q5T749 SPRY3 Homo sapiens O43610
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 CES1 Homo sapiens P23141-3
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 CES1 Homo sapiens P23141-3
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP19-6 Homo sapiens Q3LI70
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP19-6 Homo sapiens Q3LI70
Y2H Array
32296183
Intra KPRP Q5T749 SLC15A2 Homo sapiens Q16348
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 SLC15A2 Homo sapiens Q16348
Y2H Array
32296183
Intra KPRP Q5T749 RBP3 Homo sapiens P10745
Y2H Array
32296183
Intra KPRP Q5T749 RBP3 Homo sapiens P10745
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP19-1 Homo sapiens Q8IUB9
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP19-1 Homo sapiens Q8IUB9
Y2H Array
32296183
Intra KPRP Q5T749 CNFN Homo sapiens Q9BYD5
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 CNFN Homo sapiens Q9BYD5
Validated Y2H
32296183
Intra KPRP Q5T749 CNFN Homo sapiens Q9BYD5
Y2H Array
32296183
Intra KPRP Q5T749 LIMS1 Homo sapiens P48059-3
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 LIMS1 Homo sapiens P48059-3
Y2H Array
32296183
Intra KPRP Q5T749 FAM72B Homo sapiens Q86X60-2
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 FAM72B Homo sapiens Q86X60-2
Validated Y2H
32296183
Intra KPRP Q5T749 FAM72B Homo sapiens Q86X60-2
Y2H Array
32296183
Intra KPRP Q5T749 NR4A3 Homo sapiens Q92570
Validated Y2H
32296183
Intra KPRP Q5T749 NR4A3 Homo sapiens Q92570
Y2H Array
32296183
Intra KPRP Q5T749 NR4A3 Homo sapiens Q92570
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 UBASH3B Homo sapiens Q8TF42
Validated Y2H
32296183
Intra KPRP Q5T749 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra KPRP Q5T749 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra KPRP Q5T749 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra KPRP Q5T749 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP6-3 Homo sapiens Q3LI67
Y2H Array
32296183
Intra KPRP Q5T749 KRTAP6-3 Homo sapiens Q3LI67
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 RNF38 Homo sapiens Q9H0F5
Validated Y2H
32296183
Intra KPRP Q5T749 FBXO17 Homo sapiens Q96EF6
Validated Y2H
32296183
Intra KPRP Q5T749 PPIL1 Homo sapiens Q9Y3C6
Validated Y2H
32296183
Intra KPRP Q5T749 SH3KBP1 Homo sapiens Q96B97
Validated Y2H
32296183
Intra KPRP Q5T749 AKAP8L Homo sapiens Q9ULX6
Validated Y2H
32296183
Intra KPRP Q5T749 AKAP8L Homo sapiens Q9ULX6
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 AKAP8L Homo sapiens Q9ULX6
Y2H Array
32296183
Intra KPRP Q5T749 GLRX3 Homo sapiens O76003
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 GLRX3 Homo sapiens O76003
Y2H Array
32296183
Intra KPRP Q5T749 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra KPRP Q5T749 HSD3B7 Homo sapiens Q9H2F3
Validated Y2H
32296183
Intra KPRP Q5T749 TRIM42 Homo sapiens Q8IWZ5
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
32296183
Intra KPRP Q5T749 TRIM42 Homo sapiens Q8IWZ5
Y2H Array
32296183
Intra KPRP Q5T749 HEXIM2 Homo sapiens Q96MH2
Validated Y2H
32296183
Intra KPRP Q5T749 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
32296183
Intra KPRP Q5T749 LCE3D Homo sapiens Q9BYE3
Validated Y2H
32296183
Intra KPRP Q5T749 SPRED2 Homo sapiens Q7Z698
Validated Y2H
32296183
Intra KPRP Q5T749 PLA2G10 Homo sapiens O15496
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 PLA2G10 Homo sapiens O15496
Y2H Array
32296183
Intra KPRP Q5T749 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra KPRP Q5T749 GRAP2 Homo sapiens O75791
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 GRAP2 Homo sapiens O75791
Y2H Array
32296183
Intra KPRP Q5T749 OTX1 Homo sapiens P32242
Y2H Array
32296183
Intra KPRP Q5T749 OTX1 Homo sapiens P32242
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra KPRP Q5T749 CNNM3 Homo sapiens Q8NE01
Validated Y2H
32296183
Intra KPRP Q5T749 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra KPRP Q5T749 TRIP6 Homo sapiens Q15654
Validated Y2H
32296183
Intra KPRP Q5T749 NTN4 Homo sapiens Q9HB63
Validated Y2H
32296183
Intra KPRP Q5T749 CATSPER1 Homo sapiens Q8NEC5
Validated Y2H
32296183
Intra KPRP Q5T749 TEKT4 Homo sapiens Q8WW24
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP3-2 Homo sapiens Q9BYR7
Validated Y2H
32296183
Intra KPRP Q5T749 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Array
32296183
Intra KPRP Q5T749 PLSCR4 Homo sapiens Q9NRQ2
Validated Y2H
32296183
Intra KPRP Q5T749 MAPKBP1 Homo sapiens O60336
Y2H Prey Pooling
32296183
Intra KPRP Q5T749 TNS2 Homo sapiens Q63HR2
Validated Y2H
32296183
Intra KPRP Q5T749 DMRT3 Homo sapiens Q9NQL9
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Pancreatic Squamous Cell Carcinoma
Autosomal Recessive Congenital Ichthyosis

Lamellar Ichthyosis

Congenital Ichthyosiform Erythroderma

Li

Congenital Nonbullous Ichthyosiform Erythroderma

Arci

Congenital Lamellar Ichthyosis

Nonbullous Congenital Ichthyosiform Erythroderma

Cie

Congenital Non-Bullous Ichthyosiform Erythroderma

Erythrodermic Ichthyosis

Nbcie

Ncie

Non-Bullous Congenital Ichthyosiform Erythroderma

Collodion Baby

Ichthyosis, Lamellar

Non Bullous Congenital Ichthyosiform Erythroderma

Ichthyosiform Erythroderma, Brocq Congenital, Nonbullous Form

Ichthyosiform Erythroderma, Congenital, Nonbullous, 1

Collodion Baby Syndrome

Ichthyoses, Lamellar

Nbie

Nonbullous Ichthyosiform Erythroderma

Classic Lamellar Ichthyosis

Ichthyosiform Erythroderma Nonbullous Congenital

Ichthyosiform Erythroderma Congenital

Ichthyosis, Congenital, Autosomal Recessive

Ichthyosiform Erythroderma, Congenital

Collodion Fetus

Non-Bullous Ichthyosiform Erythroderma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07423 KPRP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KPRP RGD RGD:1303244
Bos taurus KPRP VGNC VGNC:30708
Macaca mulatta KPRP VGNC VGNC:106400
Mus musculus KPRP MGD MGI:1920981