Search Result

Results for "

α-Glucosidase Inhibitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glucosidase (185) AMPK (1) Amylases (25) Antibiotic (3) Apoptosis (9) Aryl Hydrocarbon Receptor (2) Bacterial (8) Bcl-2 Family (1) Carbonic Anhydrase (1) Cholinesterase (ChE) (4) COX (2) Dengue virus (3) Dipeptidyl Peptidase (4) DNA/RNA Synthesis (2) Endogenous Metabolite (11) Enterovirus (1) Flavivirus (3) Fungal (3) Glucokinase (2) Glutaminase (1) Glutathione Peroxidase (2) HBV (2) HCV (2) HDAC (1) HIV (3) HIV Protease (1) HMG-CoA Reductase (HMGCR) (2) Interleukin Related (2) Lipoxygenase (3) NOD-like Receptor (NLR) (1) Opioid Receptor (2) P-glycoprotein (1) Parasite (3) Phosphatase (7) Phospholipase (1) PI3K (3) PPAR (2) Reactive Oxygen Species (2) TNF Receptor (2) Tyrosinase (3) α-synuclein (2)
By Research Areas:	Cancer (22) Cardiovascular Disease (6) Endocrinology (6) Infection (33) Inflammation/Immunology (19) Metabolic Disease (152) Neurological Disease (9)
Click Chemistry:	Azide (1)

202

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Targets Recommended: Glucosidase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-157311

α-Glucosidase-IN-45	Glucosidase	Cancer
α-Glucosidase-IN-45 (compound 11E) is an inhibitor of *α-glucosidase. α-Glucosidase*-IN-45 is a novel indol-fused pyrano[2,3-D]pyrimidine compound .

HY-163066

α-Glucosidase-IN-44	Glucosidase	Metabolic Disease
α-Glucosidase-IN-44 (compound IT4) is an inhibitor of *α-glucosidase* with IC₅₀ value of 2.35 μM. α-Glucosidase-IN-44 has an oral activity. α-Glucosidase-IN-44 suppresses fasting blood glucose levels in diabetic mice .

HY-N12347

α-Glucosidase-IN-37	Others	Inflammation/Immunology
α-Glucosidase-IN-37 (Compound 11) moderately inhibits LPS-induced NO production with an IC₅₀ value of 23.7 μM in macrophages. α-Glucosidase-IN-37 has weak inhibitory activity against α-Glucosidase .

HY-150560

α-Glucosidase-IN-11	Glucosidase	Metabolic Disease
α-Glucosidase-IN-11 is a highly permeable competitive *α-glucosidase* inhibitor with the IC₅₀ value of 0.56 μM. α-Glucosidase-IN-11 binds to Trp residues in α-glucosidase and regulates protein folding. α-Glucosidase-IN-11 can be used to regulate blood glucose levels .

HY-155344

α-Glucosidase-IN-38	Glucosidase	Metabolic Disease
α-Glucosidase-IN-38 (Compound 11j) is a potent inhibitor of α-glucosidase inhibitor with IC₅₀ of 12.44±0.38 μM.α-Glucosidase-IN-38 plays an important role in Diabetes mellitus (DM) .

HY-169251

α-Glucosidase-IN-75	Glucosidase	Cardiovascular Disease Metabolic Disease
α-Glucosidase-IN-75 (compound 13) is an *α-glucosidase* inhibitor with an IC₅₀ of 3.81 μM. α-Glucosidase-IN-75 can be used for the study of high glucose-induced cardiovascular diseases .

HY-157488

α-Glucosidase-IN-46	Glucosidase	Metabolic Disease
α-Glucosidase-IN-46 is a potent *α-glucosidase* inhibitor with an IC₅₀ of 26.0 μM. α-Glucosidase-IN-46 can be used for the research of type 2 diabetes .

HY-155030

α-Glucosidase-IN-25	Glucosidase	Metabolic Disease
α-Glucosidase-IN-25 (Compound (R)-8k) is a competitive inhibitor of α-glucosidase, with an IC₅₀ of 1.19μM and can be used for anti-diabetic research .

HY-138992

2,3-Indolobetulin	Others	Others
2,3-Indolobetulin is a pentacyclic triterpene and a derivative of betulin. 2,3-Indolobetulin can be used in the synthesis of α-glucosidase inhibitors .

HY-162673

α-Amylase/α-Glucosidase-IN-16	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-16 (compound 15) is a potent dual inhibitor of α-amylase and *α-Glucosidase* with IC₅₀ values of 0.8 and 1.2 μM, respectively. α-Amylase/α-Glucosidase-IN-16 can be used in the study of diabetes mellitus (DM) .

HY-N9075

9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one	Glucosidase	Cancer
9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one is a phytoalexin and mixed competitive α-glucosidase inhibitor of Bacillus stearothermophilus (IC₅₀: 3.86 mg/L) .

HY-146128

Anti-hyperglycemic agent-1	Glucosidase	Metabolic Disease
Anti-hyperglycemic agent-1 (compound 10) is a potent *α-Glucosidase* inhibitor, with an IC₅₀ of 0.53 μM. Anti-hyperglycemic agent-1 can be used for diabetes research .

HY-162286

α-Glucosidase-IN-50	Glucosidase	Metabolic Disease
α-Glucosidase-IN-50 (compound 8) is an inhibitor of *α-Glucosidase* .

HY-162287

α-Glucosidase-IN-51	Glucosidase	Metabolic Disease
α-Glucosidase-IN-51 (compound 9) is an inhibitor of *α-Glucosidase* .

HY-156078

α-Glucosidase-IN-32	Glucosidase	Metabolic Disease
α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive and orally active α-glucosidase inhibitor with an IC₅₀ value of 3.07 μM. α-Glucosidase-IN-32 complex with α-glucosidase through hydrogen bonds and hydrophobic interactions, led to changes in the conformation and secondary strictures of α-glucosidase and further the inhibition of the enzymatic activity. α-Glucosidase-IN-32 can be used for diabetic disease research .

HY-157489

α-Glucosidase-IN-47	Glucosidase	Metabolic Disease
α-Glucosidase-IN-47 (compound 8H) is a non-competitive α-glucosidase (α-glucosidase) inhibitor with IC₅₀ value is 38.2 μM and K_i value is 38.2 μM. α-Glucosidase-IN-47 can be used in diabetes research. .

HY-149579

α-Glucosidase-IN-36	Glucosidase	Metabolic Disease
α-Glucosidase-IN-36 (compound 5g) is a potent *α-glucosidase* inhibitor, with an IC₅₀ of 6.69 ± 0.18 μM, K_i and K_is of 1.65 μM and 4.54 μM, respectively. α-Glucosidase-IN-36 may inhibit α-glucosidase activity by binding with its active site as well as changing the secondary structure of α-glucosidase. α-Glucosidase-IN-36 can be used for type 2 diabetes mellitus (T2DM) research .

HY-N2223

Ganoderol B Ganodermadiol	Glucosidase	Metabolic Disease
Ganoderol B is a potent *α-glucosidase* inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC₅₀ of 48.5 μg/mL (119.8 μM) .

HY-N8120

Bisabolone oxide A	Glucosidase	Metabolic Disease
Bisabolone oxide A is an *α-glucosidase* inhibitor .

HY-146156

α-Glucosidase-IN-7	Glucosidase	Metabolic Disease
α-Glucosidase-IN-7 is a noncompetitive *α-glucosidase* inhibitor with an IC₅₀ value of 18.9 µM .

HY-150960

α-Glucosidase-IN-13	Glucosidase	Metabolic Disease
α-Glucosidase-IN-13 (Compound 8) is a *α-glucosidase* inhibitor with an IC₅₀ of 5.69 μM .

HY-125713

Ganoderic acid Y	Glucosidase Enterovirus	Infection
Ganoderic acid Y is a *α-glucosidase* inhibitor with an IC₅₀ of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating .

HY-N0374

Licochalcone C 2 Publications Verification	Glucosidase	Metabolic Disease
Licochalcone C could inhibit *α-glucosidase, with IC₅₀s* of <100 nM and 92.43 μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

HY-149341

α-Glucosidase-IN-28	Glucosidase	Metabolic Disease
α-Glucosidase-IN-28 (Compound 18) is a *α-Glucosidase* inhibitor (IC₅₀: 0.62 μM, K_i: 3.93 μM). α-Glucosidase-IN-28 binds to α-glucosidase at the original binding site (OBS), and forms multiple hydrophobic interactions with nearby amino acids. α-Glucosidase-IN-28 can be used for research of diabetes and related diseases .

HY-146225

α-Amylase/α-Glucosidase-IN-2	Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and *α-glucosidase* dual inhibitor with IC₅₀ values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications .

HY-150959

α-Glucosidase-IN-12	Glucosidase	Metabolic Disease
α-Glucosidase-IN-12 (compound 14) is a potent *α-glucosidase* inhibitor, with an IC₅₀ of 10.20 μM .

HY-150961

α-Glucosidase-IN-14	Glucosidase	Metabolic Disease
α-Glucosidase-IN-14 (compound 5) is a potent *α-glucosidase* inhibitor, with an IC₅₀ of 5.22 μM .

HY-162262

α-Glucosidase-IN-48	Glucosidase	Metabolic Disease
α-Glucosidase-IN-48 (compound 9) is a potent inhibitor of α-Glucosidase, with IC₅₀ of 1.30 μM .

HY-162395

α-Glucosidase-IN-58	Glucosidase	Metabolic Disease
α-Glucosidase-IN-58 (Compound 6d) is an inhibitor for α-glucosidase with IC₅₀ of 1.47 μM .

HY-U00090

N-Methylmoranoline MOR 14; N-Methyl-1-deoxynojirimycin; N-Methylmoranolin	Glucosidase	Metabolic Disease
N-Methylmoranoline (MOR 14) is an *α-glucosidase* inhibitor.

HY-N3962

Glycyrrhisoflavone	Glucosidase	Metabolic Disease
Glycyrrhisoflavone, an active prenylflavonoid, inhibits *α-glucosidase* .

HY-147879

α-Glucosidase-IN-8	Glucosidase	Metabolic Disease
α-Glucosidase-IN-8 (Compound 4k) is a competitive *α-glucosidase* inhibitor with an IC₅₀ of 0.18 µg/mL .

HY-156447

α-Glucosidase-IN-40	Glucosidase	Metabolic Disease
α-Glucosidase-IN-40 (compound 5) is a noncompetitive α-glucosidase enzyme inhibitor with an IC₅₀ of 24.62 μM .

HY-115978

α-Glucosidase-IN-2	Glucosidase	Metabolic Disease
α-Glucosidase-IN-2 (compound 5d) is a potent *α-Glucosidase* inhibitor with an IC₅₀ of 9.48 µM. α-Glucosidase-IN-2 is an antidiabetic agent .

HY-N11512

α-Glucosidase-IN-24	Glucosidase	Metabolic Disease
α-Glucosidase-IN-24 (Compound 13) is an *α-Glucosidase* inhibitor with an IC₅₀ of 451 μM. α-Glucosidase-IN-24 can be isolated from Swertia kouitchensis .

HY-155372

α-Glucosidase-IN-39	Glucosidase	Metabolic Disease
α-Glucosidase-IN-39 is a potent inhibitor of α-glucosidase enzyme with an IC₅₀ of 869.06 ppm. α-Glucosidase-IN-39 can used in study antidiabetic .

HY-119593

α-Homonojirimycin Homonojirimycin	Glucosidase	Metabolic Disease
α-Homonojirimycin is a potent *α-glucosidase* inhibitor .

HY-147823

α-Glucosidase-IN-6	Glucosidase	Metabolic Disease
α-Glucosidase-IN-6 (compound 18) is a competitive *α-glucosidase* inhibitor with an IC₅₀ of 5.69 µM. α-Glucosidase-IN-6 has anti-diabetic potential .

HY-161318

α-Glucosidase-IN-52	Glucosidase	Metabolic Disease
α-Glucosidase-IN-52 (Compound 3h) is an *α-glucosidase* inhibitor with an IC₅₀ of 2.8 μM. α-Glucosidase-IN-52 can be used for diabetes research .

HY-168594

α-Glucosidase/NLRP3-IN-1	Glucosidase NOD-like Receptor (NLR)	Neurological Disease Metabolic Disease
α-Glucosidase/NLRP3-IN-1 (Compound 8) is a dual inhibitor of *α-glucosidase* and NLRP3, exhibiting an IC₅₀ of 6.6 μM against α-glucosidase and inhibiting NLRP3 in multiple cell lines at a concentration of 100 μM. α-Glucosidase/NLRP3-IN-1 demonstrates neuroprotective and antidiabetic properties, and can be utilized in relevant research .

HY-W005598

2-Hydroxyquinoline	Glucosidase	Metabolic Disease
2-Hydroxyquinoline is a potent *α-glucosidase* inhibitor with IC₅₀ values of 64.4, 130.5 µg/mL for α-glucosidase and α-amylase, respectively. 2-Hydroxyquinoline has the potential for the research of diabetes .

HY-147718

α-Glucosidase-IN-5	Glutaminase	Metabolic Disease
α-Glucosidase-IN-5 (compound 8) is a potent *α-glucosidase* inhibitor with an IC₅₀ of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabetes mellitus .

HY-151142

α-Glucosidase-IN-18	Glucosidase	Metabolic Disease
α-Glucosidase-IN-18 (7B) is an orally active *α-glucosidase* inhibitor with an IC₅₀ value of 3.96 μM. α-Glucosidase-IN-18 has antidiabetic activity .

HY-147964

α-Glucosidase-IN-9	Glucosidase	Metabolic Disease
α-Glucosidase-IN-9 (compound 7) is a potent *α-glucosidase* inhibitor, with an IC₅₀ of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research .

HY-147965

α-Glucosidase-IN-10	Glucosidase	Metabolic Disease
α-Glucosidase-IN-10 (compound 13) is a potent *α-glucosidase* inhibitor, with an IC₅₀ of 92.7 μM. α-Glucosidase-IN-10 can be used for type II diabetes research .

HY-151141

α-Glucosidase-IN-17	Glucosidase	Metabolic Disease
α-Glucosidase-IN-17 (Compound 12B) is a potent, orally active *α-glucosidase* inhibitor with an IC₅₀ of 3.79 μM. α-Glucosidase-IN-17 shows antidiabetic activity .

HY-151135

α-Glucosidase-IN-15	Glucosidase	Metabolic Disease
α-Glucosidase-IN-15 (Compound 14B) is a potent, orally active *α-glucosidase* inhibitor with an IC₅₀ of 3.34 μM. α-Glucosidase-IN-15 shows antidiabetic activity .

HY-161522

α-Glucosidase-IN-63	Glucosidase Carbonic Anhydrase	Endocrinology
α-Glucosidase-IN-63 (Compound 4d) is an inhibitor of *α-Glucosidase* (IC₅₀=0.44 μM). α-Glucosidase-IN-63 inhibits hCA II with an activity of K_i= 7.0 nM. α-Glucosidase-IN-63 is orally effective. .

HY-151145

α-Glucosidase-IN-21	Glucosidase	Metabolic Disease
α-Glucosidase-IN-21 (Compound 2B) is a potent, orally active *α-glucosidase* inhibitor with an IC₅₀ of 2.62 μM. α-Glucosidase-IN-21 shows anti-diabetic activity .

HY-151143

α-Glucosidase-IN-19	Glucosidase	Metabolic Disease
α-Glucosidase-IN-19 (Compound 6B) is a potent, orally active *α-glucosidase* inhibitor with an IC₅₀ of 3.63 μM. α-Glucosidase-IN-19 shows anti-diabetic activity .

Cat. No.	Product Name		Classification

HY-145273

EB-0150		Azide
EB-0150 is a potent inhibitor of *ER α-glucosidases* (α-Glu) Iand II with IC₅₀**s of 0.73 and 0.0337 μM, respectively. EB-0150 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0150 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses . EB-0150 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

α-Glucosidase Inhibitor

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Click Chemistry

Natural
Products