Search Result

Results for "

AT1 receptors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Angiotensin Receptor (70) Angiotensin-converting Enzyme (ACE) (1) Apelin Receptor (APJ) (1) Apoptosis (12) Autophagy (6) Drug Metabolite (2) Endogenous Metabolite (3) Endothelin Receptor (1) Isotope-Labeled Compounds (10) Neprilysin (2) NF-κB (1) PPAR (2) Reactive Oxygen Species (3)
By Research Areas:	Cancer (13) Cardiovascular Disease (58) Endocrinology (35) Inflammation/Immunology (5) Metabolic Disease (8) Neurological Disease (7)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13955

Telmisartan 10+ Cited Publications BIBR 277	Angiotensin Receptor Autophagy	Cardiovascular Disease Endocrinology Cancer
Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of ¹²⁵I-AngII to AT1 receptors with IC₅₀ of 9.2 nM.

HY-17512A

Losartan potassium Maximum Cited Publications 42 Publications Verification DuP-753 potassium	Angiotensin Receptor	Cardiovascular Disease Endocrinology Cancer
Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-102093

ZD 7155(hydrochloride) 1 Publications Verification	Angiotensin Receptor	Cardiovascular Disease Endocrinology
ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 *receptor*) antagonist.

HY-17512

Losartan Maximum Cited Publications 42 Publications Verification DuP-753	Angiotensin Receptor	Cardiovascular Disease Endocrinology Cancer
Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-121313

Embusartan BAY 10-6734	Angiotensin Receptor	Neurological Disease Endocrinology
Embusartan (BAY 10-6734) is a brain-penetrant and effective **AT1 receptor blocker. Embusartan inhibits Ang II binding to brain AT1 receptors** in the nuclei of central nervous system (CNS) inside due to high lipophilic character. Embusartan is promising for research of sympathetic hyperactivity and hypertension .

HY-114586

L-158809	Angiotensin Receptor	Cancer
L-158809 is an angiotensin type 1 (AT1) receptor antagonist that prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment. L-158809 is promising for research of brain tumor .

HY-100292

SL910102	Angiotensin Receptor	Cardiovascular Disease Endocrinology
SL910102 is a nonpeptide angiotensin AT₁ receptor antagonist.

HY-101618

L162389	Angiotensin Receptor	Cardiovascular Disease
L162389 is a potent antagonist of angiotensin AT1 receptor with K_i of 28 nM.

HY-103247

EMD 66684	Angiotensin Receptor	Cardiovascular Disease
EMD 66684 is an antagonist of Angiotensin II Type 1 (AT1) receptor. EMD 66684 shows potent binding affinities for the *AT1* subtype Ang II receptor with an IC₅₀ value of 0.7 nM. EMD 66684 also serves as an antiischemic cytoprotectant ^- .

HY-13955R

Telmisartan (Standard) BIBR 277 (Standard)	Angiotensin Receptor Autophagy	Cardiovascular Disease Endocrinology
Telmisartan (Standard) is the analytical standard of Telmisartan. This product is intended for research and analytical applications. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of ¹²⁵I-AngII to AT1 receptors with IC₅₀ of 9.2 nM.

HY-A0229

Saprisartan GR 138950	Angiotensin Receptor	Others
Saprisartan (GR 138950) is a selective, long-acting AT1 receptor antagonist with low receptor dissociation kinetics.

HY-A0229A

Saprisartan potassium GR 138950 potassium	Angiotensin Receptor	Cardiovascular Disease
Saprisartan (GR 138950) potassium is a selective, long-acting **AT1 receptor** antagonist .

HY-U00188

A81988 Abbott81988	Angiotensin Receptor	Cardiovascular Disease Endocrinology
A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT₁ receptors.

HY-114412A

TD-0212 TFA	Angiotensin Receptor Neprilysin	Cardiovascular Disease Inflammation/Immunology
TD-0212 TFA is an orally active dual pharmacology angiotensin II type 1 receptor (AT₁) antagonist and neprilysin (NEP) inhibitor, with a pK_i of 8.9 for AT₁ and a pIC₅₀ of 9.2 for NEP .

HY-13955S1

Telmisartan-d4 BIBR 277-d₄	Isotope-Labeled Compounds Angiotensin Receptor Autophagy	Cardiovascular Disease Endocrinology
Telmisartan-d₄ is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2].

HY-13955S

Telmisartan-d3	Angiotensin Receptor Autophagy	Cardiovascular Disease Endocrinology
Telmisartan-d₃ is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2].

HY-17512AS

Losartan-d6 hydrochloride DuP-753-d₆ hydrochloride	Angiotensin Receptor Isotope-Labeled Compounds	Cardiovascular Disease Endocrinology Cancer
Losartan-d₆ hydrochloride is deuterated labeled Losartan potassium (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-17512AR

Losartan (potassium) (Standard) DuP-753 (potassium) (Standard)	Angiotensin Receptor	Cardiovascular Disease Endocrinology Cancer
Losartan (potassium) (Standard) is the analytical standard of Losartan (potassium). This product is intended for research and analytical applications. Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-114412

TD-0212	Angiotensin Receptor Neprilysin	Inflammation/Immunology Endocrinology
TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT₁) antagonist and neprilysin (NEP) inhibitor, with a pK_i of 8.9 for AT₁ and a pIC₅₀ of 9.2 for NEP .

HY-112824

L-162313	Angiotensin Receptor	Cardiovascular Disease
L-162313 is a non-peptide angiotensin II AT1 and AT2 receptor agonist, with IC₅₀ values of 1.1 and 2.0 nM for AT1 and AT2 receptor, respectively. L-162313 can be used for the research of vasoconstriction, aldosterone release, and cardiovascular growth .

HY-13955S2

Telmisartan-13C,d3 BIBR 277-¹³C,d₃	Isotope-Labeled Compounds Angiotensin Receptor Autophagy	Cardiovascular Disease Endocrinology
Telmisartan- ¹³C,d₃ is the ¹³C- and deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.

HY-P1515

Angiotensin II (3-8), human	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT₁ receptor.

HY-W005288S

4-Vinylphenol-d4 4-Hydroxystyrene-d₄	Apoptosis Endogenous Metabolite Isotope-Labeled Compounds	Cancer
4-Vinylphenol-d₄ is deuterated labeled Losartan (potassium) (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-106123

Pomisartan	Angiotensin Receptor	Cardiovascular Disease
Pomisartan is an orally active angiotensin II receptor type *AT1* antagonist (IC₅₀=0.26 μM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect .

HY-17005

Olmesartan medoxomil CS 866	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC₅₀ of 66.2 μM.

HY-P1515A

Angiotensin II (3-8), human TFA 2 Publications Verification	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Angiotensin II (3-8), human (TFA) is a less effective agonist at the angiotensin AT₁ receptor.

HY-13955S3

Telmisartan-d7 BIBR 277-d₇	Isotope-Labeled Compounds Autophagy Angiotensin Receptor	Cardiovascular Disease
Telmisartan-d₇ (BIBR 277-d₇) is a deuterium labeled Telmisartan (HY-13955). Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of ¹²⁵I-AngII to AT1 receptors with IC₅₀ of 9.2 nM.

HY-101542

Milfasartan LR-B/081	Angiotensin Receptor	Cardiovascular Disease
Milfasartan (LR-B/081) is a selective angiotensin receptor *AT1* antagonist with antihypertensive activity .

HY-117447

LY303336	Angiotensin Receptor	Others
LY303336 is an antagonist of polysubstituted 4-aminoimidazole AT1 receptor with an IC₅₀ value of 5.2 nM .

HY-105010

FK-739 free base	Angiotensin Receptor	Cardiovascular Disease
FK-739 (free base) is an angiotensin II type 1 (AT1) receptor antagonist used in the study of hypertension .

HY-17512S

Losartan-d4 DuP-753 d₄	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Losartan-d₄ is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

HY-105440

LY 301875	Angiotensin Receptor	Cardiovascular Disease
LY 301875 is a potent and orally active angiotensin II receptor type 1 (AT1) antagonist with a pK_B value of 9.6 .

HY-17512S1

Losartan-d3 Carboxylic Acid	Isotope-Labeled Compounds Angiotensin Receptor	Others
Losartan-d₃ Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-B0202S

Irbesartan-d4 SR-47436-d₄; BMS-186295-d₄	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Irbesartan-d₄ is the deuterium labeled Irbesartan, which is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist.

HY-17512S3

Losartan-d2 DuP-753-d₂	Angiotensin Receptor	Others
Losartan-d₂ is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512S4

Losartan-d9 DuP-753-d₉	Angiotensin Receptor	Others
Losartan-d₉ is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512R

Losartan (Standard)	Angiotensin Receptor	Cardiovascular Disease Endocrinology Cancer
Losartan (Standard) is the analytical standard of Losartan. This product is intended for research and analytical applications. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-131264

Olmesartan medoxomil impurity C Dehydro Olmesartan medoxomil	Angiotensin Receptor	Metabolic Disease
Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC₅₀ of 66.2 μM.

HY-19214

Elisartan HN 65021	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Elisartan is an orally active non-peptide pro-agent of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities.

HY-100113

Buloxibutid 4 Publications Verification AT2 receptor agonist C21	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Buloxibutid (AT2 receptor agonist C21) is a agentlike selective angiotensin II AT2 receptor agonist with K_i values of 0.4 nM and >10 μM for the AT2 receptor and AT1 receptor, respectively .

HY-102093R

ZD 7155(hydrochloride) (Standard)	Angiotensin Receptor	Cardiovascular Disease Endocrinology
ZD 7155(hydrochloride) (Standard) is the analytical standard of ZD 7155(hydrochloride). This product is intended for research and analytical applications. ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.

HY-131278

Olmesartan methyl ester	Angiotensin Receptor	Cardiovascular Disease
Olmesartan methyl ester is an intermediate in the synthesis of Olmesartan medoxomil. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor antagonist with IC₅₀ of 66.2 μM .

HY-B0202S1

Irbesartan-d6	Angiotensin Receptor Apoptosis	Cardiovascular Disease Endocrinology
Irbesartan-d₆ is the deuterium labeled Irbesartan. Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

HY-117805

UR-7247	Angiotensin Receptor	Cardiovascular Disease
UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow .

HY-N14205

Cytosporin A	Angiotensin Receptor	Others
Cytosporin A is a hexahydrobenzopyran derivative and an angiotensin II receptor antagonist. Cytosporin A has IC₅₀ values of 25-30 μM and 1.5-3 μM for *AT₁* and AT₂, respectively .

HY-D0845

Nitrosoglutathione GSNO; RVC-588; S-Nitroso-L-glutAThione	Endogenous Metabolite Angiotensin Receptor	Cardiovascular Disease Inflammation/Immunology
Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses .

HY-17005R

Olmesartan medoxomil (Standard) CS 866 (Standard)	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Olmesartan medoxomil (Standard) is the analytical standard of Olmesartan medoxomil. This product is intended for research and analytical applications. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC₅₀ of 66.2 μM.

HY-101823A

A-81282 Abbott 81282	Angiotensin Receptor	Cardiovascular Disease
A-81282 (Abbott 81282) is an antagonist of angiotensin II's *AT1* receptor, with a p_A2 value of 9.64 at the *AT1* receptor in rabbit aorta. A-81282 also demonstrates significant inhibitory action on the binding of [125i]_Sar1_lle8_Angiotensin_ll to rat liver membranes, with a p_KI value of 8.505. A-81282 has antihypertensive activity and can effectively lower blood pressure in renal artery-ligated rats .

HY-114953

BMS-248360	Angiotensin Receptor Endothelin Receptor	Cardiovascular Disease
BMS-248360 is a potent and orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ET_A) receptor, with K_is of 10 nM and 1.9 nM for hAT1 and hETA receptor, respectively. BMS-248360 displays hypertensive effects .

HY-12765

Losartan Carboxylic Acid E-3174; EXP-3174	Drug Metabolite Angiotensin Receptor	Cardiovascular Disease
Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The K_i values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure .

Cat. No.	Product Name	Target	Research Area

HY-P3138

(Sar1)-Angiotensin II	Angiotensin Receptor	Cardiovascular Disease
(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a K_d of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes .

HY-P1769

Angiotensin II (5-8), human	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (5-8), human is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II . Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

HY-P1515

Angiotensin II (3-8), human	Angiotensin Receptor	Cardiovascular Disease Endocrinology
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT₁ receptor.

HY-110183

Angiotensin A	Peptides	Cardiovascular Disease
Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT₁ receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats .

HY-P1792A

Angiotensin II (1-4), human TFA	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (1-4), human (TFA) is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

HY-P1792

Angiotensin II (1-4), human	Angiotensin Receptor	Metabolic Disease Endocrinology
Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca ²⁺ levels. Angiotensin II also acts at the Na ⁺/H ⁺ exchanger in the proximal tubules of the kidney .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N14205

Cytosporin A	Structural Classification Natural Products Microorganisms Source classification	Angiotensin Receptor
Cytosporin A is a hexahydrobenzopyran derivative and an angiotensin II receptor antagonist. Cytosporin A has IC₅₀ values of 25-30 μM and 1.5-3 μM for *AT₁* and AT₂, respectively .

Cat. No.	Product Name	Chemical Structure

HY-13955S

Telmisartan-d3
Telmisartan-d₃ is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2].

HY-13955S3

Telmisartan-d7
Telmisartan-d₇ (BIBR 277-d₇) is a deuterium labeled Telmisartan (HY-13955). Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of ¹²⁵I-AngII to AT1 receptors with IC₅₀ of 9.2 nM.

HY-17512S

Losartan-d4
Losartan-d₄ is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

HY-B0202S

Irbesartan-d4
Irbesartan-d₄ is the deuterium labeled Irbesartan, which is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist.

HY-13955S1

Telmisartan-d4
Telmisartan-d₄ is the deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM[1][2].

HY-17512AS

Losartan-d6 hydrochloride
Losartan-d₆ hydrochloride is deuterated labeled Losartan potassium (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-13955S2

Telmisartan-13C,d3
Telmisartan- ¹³C,d₃ is the ¹³C- and deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.

HY-W005288S

4-Vinylphenol-d4
4-Vinylphenol-d₄ is deuterated labeled Losartan (potassium) (HY-17512A). Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC₅₀ of 20 nM.

HY-17512S1

Losartan-d3 Carboxylic Acid
Losartan-d₃ Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512S3

Losartan-d2
Losartan-d₂ is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-17512S4

Losartan-d9
Losartan-d₉ is the deuterium labeled Losartan[1]. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC₅₀ of 20 nM.

HY-B0202S1

Irbesartan-d6
Irbesartan-d₆ is the deuterium labeled Irbesartan. Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.

HY-17005S

Olmesartan medoxomil-d6
Olmesartan medoxomil-d₆ (CS 866-d6) is the deuterium labeled Olmesartan medoxomil. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM[1][2].

HY-12765S1

Losartan carboxylic acid-d4 hydrochloride

Losartan carboxylic acid-d₄ (hydrochloride) is deuterium labeled Losartan Carboxylic Acid. Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4].

HY-14914S1

Azilsartan-d4
Azilsartan-d₄ is the deuterium labeled Azilsartan[1]. Azilsartan is an orally active, potent, selective and specific angiotensin II type 1 receptor (AT1) antagonist. Azilsartan induces ROS formation and apoptosis in HepG2 cells. Azilsartan shows neuroprotective and anticancer activity. Azilsartan can be used for hypertension and stroke research[2][3][4][5][6].

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active *Ang II type 1 (AT1) receptor* blocker (ARB)**. Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202S2

Irbesartan-d6-1
Irbesartan-d₆-1 is the deuterium labeled Irbesartan[1]. Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease[2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks