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Results for "

antiparasitic activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Adrenergic Receptor (2) Aminoacyl-tRNA Synthetase (1) Antibiotic (13) Apoptosis (5) Autophagy (2) Bacterial (17) Bcl-2 Family (2) Carbonic Anhydrase (1) Caspase (2) Cholinesterase (ChE) (1) Dihydrofolate reductase (DHFR) (3) Endogenous Metabolite (4) Farnesyl Transferase (1) Fungal (11) HDAC (1) HIF/HIF Prolyl-Hydroxylase (3) HSV (2) Influenza Virus (1) Isotope-Labeled Compounds (3) Microtubule/Tubulin (3) Na+/K+ ATPase (1) Necroptosis (2) Oxidative Phosphorylation (2) p38 MAPK (2) Parasite (89) PARP (2) PI4K (1) Platelet-activating Factor Receptor (PAFR) (1) Raf (2) SARS-CoV (2)
By Research Areas:	Cancer (17) Cardiovascular Disease (3) Infection (93) Inflammation/Immunology (20) Metabolic Disease (1) Neurological Disease (11)

By Targets:

5-HT Receptor (3)

Adrenergic Receptor (2)

Aminoacyl-tRNA Synthetase (1)

Antibiotic (13)

Apoptosis (5)

Autophagy (2)

Bacterial (17)

Bcl-2 Family (2)

Carbonic Anhydrase (1)

Caspase (2)

Cholinesterase (ChE) (1)

Dihydrofolate reductase (DHFR) (3)

Endogenous Metabolite (4)

Farnesyl Transferase (1)

Fungal (11)

HDAC (1)

HIF/HIF Prolyl-Hydroxylase (3)

HSV (2)

Influenza Virus (1)

Isotope-Labeled Compounds (3)

Microtubule/Tubulin (3)

Na+/K+ ATPase (1)

Necroptosis (2)

Oxidative Phosphorylation (2)

p38 MAPK (2)

Parasite (89)

PARP (2)

PI4K (1)

Platelet-activating Factor Receptor (PAFR) (1)

Raf (2)

SARS-CoV (2)

By Research Areas:

Cancer (17)

Cardiovascular Disease (3)

Infection (93)

Inflammation/Immunology (20)

Metabolic Disease (1)

Neurological Disease (11)

100

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1400

Diiodohydroxyquinoline 1 Publications Verification Iodoquinol; 5,7-Diiodo-8-hydroxyquinoline; 5,7-Diiodo-8-quinolinol	Parasite SARS-CoV	Infection Inflammation/Immunology
Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC₅₀ value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .

HY-113562

Laidlomycin phenylcarbamate	Antibiotic Parasite	Infection
Laidlomycin phenylcarbamate is a semisynthetic polyether antibiotic with antiparasitic activity .

HY-161666

mCMY416	Aminoacyl-tRNA Synthetase Parasite	Infection
mCMY416 is an orally active and blood brain barrier (BBB) permeability apicomplexan phenylalanine tRNA synthetase inhibitor, and shows antiparasitic activity .

HY-157466

Antiparasitic agent-21	Parasite	Infection
Antiparasitic agent-21 (compound 28) has selectively antiparasitic activity against Naegleria fowleri with an EC₅₀ of 0.92 μM. Antiparasitic agent-21 has excellent blood-brain barrier permeability .

HY-149078

Antiparasitic agent-14	Parasite	Infection
Antiparasitic agent-14 is a potemt *antiparasitic* agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote .

HY-B0226A

(E)-Nitrofurazone (E)-Nitrofural	Bacterial Parasite	Infection
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .

HY-151133

Antiparasitic agent-9	Parasite	Infection
Antiparasitic agent-9 (compound 47) is an orally active and potent antiparasitic agent. Antiparasitic agent-9 shows antiparasitic activity against the human parasite .

HY-151433

Antiparasitic agent-10	Parasite	Infection
Antiparasitic agent-10 (Compound 94) is an *anti-parasitic* agent, shows anti-schistosomal activity. Antiparasitic agent-10 shows activity against adults of Schistosoma mansoni, and can be used in Schistosomiasis research .

HY-157028

Antiparasitic agent-19	Others	Infection
Antiparasitic agent-19 (compound 40) is a compound with broad-spectrum antiparasitic activity. Antiparasitic agent-19 has minimal toxicity against Trypanosoma brucei, Leishmania Infantum, and Trypanosoma cruzi .

HY-B1400R

Diiodohydroxyquinoline (Standard)	Parasite SARS-CoV	Infection Inflammation/Immunology
Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .

HY-149722

Antiparasitic agent-20	Parasite	Infection
Antiparasitic agent-20 (Compound 1p) is a parasite inhibitor with broad antiparasitic activity. Antiparasitic agent-20 has inhibitory effects on T. brucei and T. cruzi with EC₅₀ values of 0.09 μM and 14.1 μM respectively .

HY-146044

Antiparasitic agent-6	Parasite	Infection
Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC₅₀ = 13.64 μM) .

HY-146043

Antiparasitic agent-5	Parasite	Infection
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC₅₀ = 6.78 μM) .

HY-146045

Antiparasitic agent-7	Parasite	Infection
Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC₅₀ value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC₅₀ = 10.61 μM) .

HY-147806

Antiparasitic agent-8	Parasite	Infection
Antiparasitic agent-8 (Compound 9) is an antiparasitic agent against Hymenolepis nana with low cytotoxicity .

HY-N2656

5,7,8-Trimethoxycoumarin	Parasite	Infection
5,7,8-Trimethoxycoumarin is an anti-parasite agent with IC₅₀s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively .

HY-160985

Lemidosul	Parasite	Others
Lemidosul is an anti-trypanosomiasis compound that can be further optimized for its performance as an anti-trypanosomiasis drug by means of a computer-aided drug design (CADD) approach .

HY-125298

Cycloaspeptide A	Parasite	Infection
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has *antiparasitic* activity .

HY-155087

Anticancer agent 140	Parasite	Infection Cancer
Anticancer agent 140 (Compd 3) is a compound with potential anticancer and antiparasitic activities .

HY-146042

Antiparasitic agent-4	Parasite	Infection
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC₅₀s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC₅₀ = 18.97 μM) .

HY-146041

Antiparasitic agent-2	Parasite	Infection
Antiparasitic agent-2 (compound 8a) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC₅₀s of 7.28 μM and 2.30 μM, respectively. Antiparasitic agent-2 also has certain cytotoxicity against HepG2 (CC₅₀ = 26.79 μM) .

HY-149079

Antiparasitic agent-15	Parasite Necroptosis	Infection
Antiparasitic agent-15, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-15 has IC₅₀s of 0.9 μM and 0.64 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-15 has IC₅₀s of 42.2 μM and 9.58 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-15 induces parasite cell death through necrosis induction. Antiparasitic agent-15 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .

HY-149080

Antiparasitic agent-16	Parasite Necroptosis	Infection
Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC₅₀s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi. Antiparasitic agent-16 has IC₅₀s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis. Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes .

HY-10502

Tipifarnib 5+ Cited Publications IND 58359; R115777	Farnesyl Transferase	Infection Cancer
Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC₅₀ of 0.86 nM. Antineoplastic activity and antiparasitic activity .

HY-N10769

Atanine	Parasite	Infection
Atanine is an alkaloid with antiparasitic activity. Atanine can be isolated from medicinal plant, Evodia rutaecarpa .

HY-118495

Cardol diene	Parasite	Infection
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-155281

Antiparasitic agent-18	Parasite	Infection
Antiparasitic agent-18 (compound 3a) is active and selective against the T. brucei (EC₅₀=0.4 μM), T. cruzi (EC₅₀=0.21 μM), and L. donovani (EC₅₀=0.26 μM). Antiparasitic agent-18 has potent antiprotozoal activity .

HY-N0924A

(±)-Stylopine hydrochloride 1 Publications Verification Tetrahydrocoptisine hydrochloride	Parasite	Inflammation/Immunology
(±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-N0924

(±)-Stylopine 1 Publications Verification Tetrahydrocoptisine	Parasite	Inflammation/Immunology
(±)-Stylopine (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P1975

Aureobasidin A 2 Publications Verification Basifungin	Fungal Parasite	Infection Inflammation/Immunology
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and *antiparasitic* activity .

HY-75247

Coumaran 2 Publications Verification 2,3-Dihydrobenzofuran	Cholinesterase (ChE) Endogenous Metabolite Parasite	Infection Neurological Disease Inflammation/Immunology
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide. .

HY-146747

Antifungal agent 26	Fungal Parasite	Infection Inflammation/Immunology
Antifungal agent 26, a Pradimicin A derivative, shows antifungal, antiviral, and antiparasitic activities through binding to d-mannose (Man)-containing glycans of pathogenic species .

HY-121054

Chalcone	Bacterial Parasite	Inflammation/Immunology Cancer
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-129130

Canthin-6-one N-oxide Canthin-6-one 3-oxide	Parasite	Infection
Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active *antiparasitic* agent with limited activity .

HY-122382

Levofuraltadone NF-602	Parasite Bacterial	Infection
Levofuraltadone (NF-602) is an antibacterial and antiparasitic agent. Levofuraltadone has anti-trypanosomiasis activity and can be used in the study of human african trypanosomiasis as well as bacterial infections .

HY-B1056

Procodazole Propazol; 2-Benzimidazolepropionic acid	Bacterial Parasite Antibiotic Carbonic Anhydrase	Infection Cancer
Procodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity .

HY-12642

Diethylcarbamazine citrate	Parasite	Infection Inflammation/Immunology
Diethylcarbamazine citrate is an orally active anthropoidal compound. Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism of filaria microfilaria. Diethylcarbamazine citrate has anti-inflammatory and *antiparasitic* activity .

HY-N10402

Norbatzelladine L	Fungal Bacterial Parasite	Infection Cancer
Norbatzelladine L (Compound 2) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Norbatzelladine L inhibits Pdr5p ATPase activity with an IC₅₀ of 3.8 µM. Norbatzelladine L shows antifungal, *antiparasitic, antiviral, antibacterial* and antitumoral activities .

HY-150506

SPR7	Parasite	Infection
SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a K_i of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC₅₀ of 1.65 μM .

HY-118383

Agathisflavone	Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-161309

PfPKG-IN-2	Parasite	Infection
PfPKG-IN-2 (compound 53) is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with an IC₅₀ value of 13 nM. PfPKG-IN-2 shows antiparasitic activity .

HY-162656

DHFR-IN-19	Dihydrofolate reductase (DHFR)	Infection
DHFR-IN-19 (Compound 2g) is a selective inhibitor for TbDHFR with K_i of 9 nM. DHFR-IN-19 exhibits antiparasitic activity against Trypanosoma brucei with an EC₅₀ of 14.5 μM .

HY-N1451

Betulonic acid 2 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Parasite HSV	Infection Inflammation/Immunology Cancer
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N8846

dl-Aloesol	Fungal	Infection
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

HY-120809

Spiramycin III	Bacterial Parasite Antibiotic	Infection
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-N10401

Batzelladine D	Fungal Bacterial Parasite	Infection Cancer
Batzelladine D (Compound 1) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Batzelladine D inhibits Pdr5p ATPase activity with an IC₅₀ of 7.1 µM. Batzelladine D shows antifungal, *antiparasitic, antiviral, antibacterial* and antitumoral activities .

HY-123230

Trifloxystrobin CGA 279202	Fungal Caspase PARP Apoptosis	Infection Neurological Disease
Trifloxystrobin (CGA 279202) is a type of fungicide. Trifloxystrobin has toxicity, antiparasitic activity and induce apoptosis, oxidative stress and DNA damage. Trifloxystrobin can be used for the reaesrch of fungal diseases .

HY-W018025

5,6-Dihydroxyindole	Bacterial Fungal Parasite Endogenous Metabolite	Infection Inflammation/Immunology
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, *antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-W012550

D-Carnitine	Parasite	Infection
D-Carnitine is an orally available isomer of the essential nutrient L-carnitine that promotes long-chain fatty acid transport into the mitochondrial matrix for beta-oxidation. D-Carnitine has antiparasitic activity .

Cat. No.	Product Name

HY-L082

Antiparasitic Compound library

489 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 489 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

Cat. No.	Product Name	Target	Research Area

HY-P1975

Aureobasidin A 2 Publications Verification Basifungin	Fungal Parasite	Infection Inflammation/Immunology
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and *antiparasitic* activity .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Peptides	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0924A

(±)-Stylopine hydrochloride 1 Publications Verification Tetrahydrocoptisine hydrochloride	Alkaloids Structural Classification Classification of Application Fields Flacourtia indica Source classification Flacourtiaceae Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields	Parasite
(±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-N0924

(±)-Stylopine 1 Publications Verification Tetrahydrocoptisine	Alkaloids Structural Classification Chelidonium majus Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Papaveraceae	Parasite
(±)-Stylopine (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities .

HY-P1975

Aureobasidin A 2 Publications Verification Basifungin	Infection Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Disease Research Inflammation/Immunology Disease Research Fields Other Antibiotics	Fungal Parasite
Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and *antiparasitic* activity .

HY-75247

Coumaran 2 Publications Verification 2,3-Dihydrobenzofuran	Structural Classification Natural Products Verbenaceae Source classification Plants Endogenous metabolite Lantana camaraLinn.	Cholinesterase (ChE) Endogenous Metabolite Parasite
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide. .

HY-121054

Chalcone	Structural Classification Chalcones Flavonoids Classification of Application Fields Leguminosae Source classification Plants Endogenous metabolite Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields	Bacterial Parasite
Chalcone is isolated from Glycyrrhiza uralensis and used to synthesize chalcone derivatives. Chalcone derivatives possess varied biological and pharmacological activity, including anti-inflammatory, antioxidative, antibacterial, anticancer, and anti-parasitic activities .

HY-N2656

5,7,8-Trimethoxycoumarin	Zanthoxylum dimorphophyllum Hemsl. Structural Classification Rutaceae Coumarins Phenylpropanoids Plants	Parasite
5,7,8-Trimethoxycoumarin is an anti-parasite agent with IC₅₀s of 25.5 μM and 57.7 μM against Trypanosoma cruzi and L. amazonensis, respectively .

HY-125298

Cycloaspeptide A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has *antiparasitic* activity .

HY-N10769

Atanine	Zanthoxylum bungeanum Maxim. Structural Classification Alkaloids Source classification Rutaceae Quinoline Alkaloids Plants	Parasite
Atanine is an alkaloid with antiparasitic activity. Atanine can be isolated from medicinal plant, Evodia rutaecarpa .

HY-118495

Cardol diene	Structural Classification Source classification Phenols Polyphenols Plants Anacardium occidentaleL. Anacardiaceae	Parasite
Cardol diene is a potent antiparasitic agent. Cardol diene shows schistosomicidal activity and inhibits cell viability .

HY-129130

Canthin-6-one N-oxide Canthin-6-one 3-oxide	Structural Classification Alkaloids Simaroubaceae Other Alkaloids Source classification Eurycoma harmandiana Pierre Plants	Parasite
Canthin-6-one N-oxide (Canthin-6-one 3-oxide) is an orally active *antiparasitic* agent with limited activity .

HY-N10402

Norbatzelladine L	Alkaloids Microorganisms Source classification	Fungal Bacterial Parasite
Norbatzelladine L (Compound 2) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Norbatzelladine L inhibits Pdr5p ATPase activity with an IC₅₀ of 3.8 µM. Norbatzelladine L shows antifungal, *antiparasitic, antiviral, antibacterial* and antitumoral activities .

HY-118383

Agathisflavone	Structural Classification Flavonoids Flavones Source classification Araucariaceae Agathis robusta (C. Moore ex F. Muell.) F. M. Bailey Plants	Parasite
Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats .

HY-N1451

Betulonic acid 2 Publications Verification Betunolic acid; Liquidambaric acid; (+)-Betulonic acid	Infection Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Parasite HSV
Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-N8846

dl-Aloesol	Structural Classification Flavonoids Microorganisms Source classification Other Flavonoids	Fungal
dl-Aloesol is a natural product that can be isolated from fungus Aspergillus sp. Aspergillus sp metabolites has cytotoxic, antibacterial, free radical scavenging, anti-parasitic, antiviral and antiproliferative activities, etc .

HY-120809

Spiramycin III	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Bacterial Parasite Antibiotic
Spiramycin III (SPMIII) is a main component of Spiramycin. Spiramycin (HY-100593) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect .

HY-N10401

Batzelladine D	Infection Alkaloids Structural Classification Classification of Application Fields Animals Other Alkaloids Marine natural products Sponge Disease Research Fields Cancer	Fungal Bacterial Parasite
Batzelladine D (Compound 1) is an inhibitor of the catalytic and functional activity of Pdr5p transporter. Batzelladine D inhibits Pdr5p ATPase activity with an IC₅₀ of 7.1 µM. Batzelladine D shows antifungal, *antiparasitic, antiviral, antibacterial* and antitumoral activities .

HY-W018025

5,6-Dihydroxyindole	Structural Classification Natural Products Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, *antiparasitic* activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-124210

Formycin B	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic Parasite
Formycin B is an antibiotic, which exhibits antiparasitic activity against Leishmania. Formycin B exhibits toxicity to leukocytes, reversibly decreases neutrophils. Formycin B can be used in research about myeloid leukemia .

HY-N6735

Apicidin 3 Publications Verification OSI 2040	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Anti-parasitic Disease Research Anticancer Disease Research Fields Other Antibiotics	HDAC Parasite
Apicidin (OSI 2040) is a fungal metabolite, acts as an orally active histone deacetylase 7/8 (HDAC7/8) inhibitor, with antiparasitic activity and a broad spectrum antiproliferative activity. Apicidin can be used for cancer research .

HY-N11920

Kadsurenin B	Structural Classification Source classification Lignans Piperaceae Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi	Platelet-activating Factor Receptor (PAFR)
Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc .

HY-N13197

5,6-Dihydro-6-methyl-2H-pyran-2-one	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial Fungal Parasite
5,6-Dihydro-6-methyl-2H-pyran-2-one is a heterocyclic compound with antitumor, antifungal, antimicrobial, anti-inflammatory, antistress, antibiotic, antituberculosis, antiparasitic, antiviral activities .

HY-100593

Spiramycin 1 Publications Verification Rovamycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Antibacterial Disease Research Disease Research Fields	Bacterial Parasite Antibiotic
Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-N10441

3β-Hydroxy-hop-22(29)-ene	Cnidoscolus spinosus Lundell Triterpenes Terpenoids Source classification Euphorbiaceae Plants	Parasite
3β-Hydroxy-hop-22(29)-ene (compound 3) is a potent *antiparasitic* agent. 3β-Hydroxy-hop-22(29)-ene shows moderate activity against Trypanosoma cruzi and Leishmania mexicana .

HY-N0397

Harpagide	Structural Classification Iridoids Classification of Application Fields Scrophularia ningpoensis Hemsl. Terpenoids Source classification Scrophulariaceae Plants Inflammation/Immunology Disease Research Fields	Parasite
Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (*T.b. rhodesiense) with an IC₅₀* of 21 μg/mL. Harpagide exerts significant antileishmanial activity against *L. donovani* with an IC₅₀ value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .

HY-N1451R

Betulonic acid (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Parasite HSV
Betulonic acid (Standard) is the analytical standard of Betulonic acid. This product is intended for research and analytical applications. Betulonic acid (Betunolic acid), a naturally occurring triterpene, is found in many plants. Betulonic acid has anti-tumor, anti-inflammatory, antiparasitic and anti-viral (HSV-1) activities .

HY-W071746

Linolelaidic acid Linoelaidic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite Parasite Apoptosis
Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections .

HY-B0778

Milbemycin oxime 1 Publications Verification	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Antibiotic Parasite
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-N0397R

Harpagide (Standard)	Structural Classification Iridoids Scrophularia ningpoensis Hemsl. Terpenoids Source classification Scrophulariaceae Plants	Parasite
Harpagide (Standard) is the analytical standard of Harpagide. This product is intended for research and analytical applications. Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC₅₀ of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC₅₀ value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities .

HY-100593R

Spiramycin (Standard)	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Anti-parasitic Antibacterial Disease Research	Bacterial Parasite Antibiotic
Spiramycin (Standard) is the analytical standard of Spiramycin. This product is intended for research and analytical applications. Spiramycin (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens with against bacteria and Toxoplasma gondii activities, and also has antiparasitic effect. Spiramycin is composed of a 16-member lactone ring, on which three sugars (mycaminose, forosamine, and mycarose) are attached .

HY-W018025R

5,6-Dihydroxyindole (Standard)	Structural Classification Natural Products Source classification Phenols Polyphenols Endogenous metabolite	Bacterial Fungal Parasite Endogenous Metabolite
5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .

HY-129278

Lunarine	Structural Classification Alkaloids Lunaria annua L. Other Alkaloids Source classification Plants Brassicaceae	Parasite
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD₅₀ of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with K_i of 304 μM .

HY-B0778R

Milbemycin oxime (Standard)	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Parasite
Milbemycin oxime (Standard) is the analytical standard of Milbemycin oxime. This product is intended for research and analytical applications. Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-N7236

Pervicoside B	Triterpenes Structural Classification Animals Terpenoids Source classification	Parasite Fungal
Pervicoside B is a glycoside C isolated from Neothyone gibbosa sea cucumber. In vitro studies have shown that Pervicoside B has a potent antiparasitic effect against Leishmania mexicana, inhibiting 100% of promastigotes at 5-10 μg/mL. Pervicoside B also exhibits strong antifungal activity against Aspergillus niger, with MIC values ranging from 4.65 to 16.7 μg/mL. Pervicoside B has potential applications in the inhibition of parasitic infections and fungal diseases .

Cat. No.	Product Name	Chemical Structure

HY-B0413S

Fenbendazole-d3

2 Publications Verification

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].

HY-17596S

Closantel-13C6
Closantel- ¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

HY-B0740S3

Cyclobenzaprine-d3-1 hydrochloride

Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT₂ receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases

HY-113050SA

2,3-Diphosphoglyceric acid-d3 ammonium

2,3-Diphosphoglyceric acid-d3 ammonium (2,3-DPG-d3 ammonium) is the deuterium labeled 2,3-Diphosphoglyceric acid (HY-113050). 2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD) .

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