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respiratory diseases

" in MedChemExpress (MCE) Product Catalog:

97

Inhibitors & Agonists

2

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1

Peptides

2

Inhibitory Antibodies

13

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13

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107355

    Others Inflammation/Immunology
    Letosteine is an orally active, potent and safe expectorant. Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3].
    Letosteine
  • HY-147240

    ADX-629

    Others Infection Cardiovascular Disease Inflammation/Immunology
    Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes .
    Acloproxalap
  • HY-137451A

    (E/Z)-S-600918

    P2X Receptor Inflammation/Immunology
    (E/Z)-Sivopixant ((E/Z)-S-600918) is a potent P2X3 receptor antagonist with an IC50 of 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research .
    (E/Z)-Sivopixant
  • HY-120632

    RSV Infection
    BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 can be used for the research of respiratory tract disease .
    BMS-433771
  • HY-120632A

    RSV Infection
    BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease .
    BMS-433771 dihydrochloride hydrate
  • HY-15280

    PI3K Inflammation/Immunology
    GSK2292767 is a potent and selective inhibitor of PI3Kδ, with a pIC50 of 10.1. GSK2292767 showing greater than 500-fold selective over the other PI3K isoforms. GSK2292767 can be used for the research of respiratory disease .
    GSK2292767
  • HY-144058

    JAK Inflammation/Immunology
    JAK-IN-18 is a potent inhibitor of JAK. JAK-IN-18 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2018204238A1, compound 1) .
    JAK-IN-18
  • HY-144057

    JAK Inflammation/Immunology
    JAK-IN-17 is a potent inhibitor of JAK. JAK-IN-17 is useful for the research of multiple diseases, particularly ocular, skin, and respiratory diseases (extracted from patent WO2021185305A1, compound 9-1) .
    JAK-IN-17
  • HY-105762A

    Others Cardiovascular Disease
    Etamiphyllin camsylate is a cardiac stimulant with oral activity that increases cardiac output without increasing heart rate. Etamiphyllin camsylate is also a respiratory stimulant used for respiratory failure, as Etamiphyllin camsylate relaxes the smooth muscles of the bronchi and bronchioles, thereby opening up the airways to relieve chronic obstructive pulmonary disease .
    Etamiphyllin camsylate
  • HY-156550

    ROCK Inflammation/Immunology
    ROCK-IN-8 (Example 4) is a ROCK inhibitor, with an IC50 value less than 100 nM. ROCK-IN-8 has anti-inflammatory activity. ROCK-IN-8 can be used for research of respiratory and gastro-intestinal diseases .
    ROCK-IN-8
  • HY-B1717

    Others Inflammation/Immunology
    Oxolamine (SKF-9976) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine also exhibits anti-inflammatory effect .
    Oxolamine
  • HY-B1717A

    Others Inflammation/Immunology
    Oxolamine (SKF-9976) hydrochloride is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine hydrochloride also exhibits anti-inflammatory effect .
    Oxolamine hydrochloride
  • HY-B1042

    SKF-9976 citrate; AF-438 citrate

    Others Inflammation/Immunology
    Oxolamine citrate (SKF-9976 citrate) is an orally active cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine citrate also exhibits anti-inflammatory effect .
    Oxolamine citrate
  • HY-N1875

    p-Hydroxybenzyl Et ether

    Others Inflammation/Immunology
    4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations .
    4-(Ethoxymethyl)phenol
  • HY-N2913

    Phosphodiesterase (PDE) Inflammation/Immunology Cancer
    Ayanin is a bioflavonoid isolated from Psychotria serpens. Ayanin is a non-selective phosphodiesterase1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al .
    Ayanin
  • HY-149235

    PI3K Inflammation/Immunology
    PI3Kδ-IN-12 (compound 13) is a PI3Kδ inhibitor (pIC50 = 5.8), with pKi values of 8.0/6.5/6.4/6.7 for PI3Kδ/γ/β/α, respectively. PI3Kδ-IN-12 can be used in the study of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) .
    PI3Kδ-IN-12
  • HY-156684

    TRP Channel Neurological Disease
    GDC-6599 is an orally active TRPA1 inhibitor, with IC50 values of 5.3 nM in humans, 6.6 nM in rats, 9.3 nM in dogs, 7.2 nM in monkeys, and 15 nM in guinea pigs. GDC-6599 can be used in the research of neuropathic pain and respiratory diseases such as asthma and chronic cough .
    GDC-6599
  • HY-N10581

    Influenza Virus Infection
    Flutimide is a novel endonuclease inhibitor of influenza virus. Flutimide selectively inhibits endonuclease with an IC50 value of 3 μM. Flutimide shows antiviral activity in cell culture. Flutimide can be used for the research of acute contagious respiratory disease, such as influenza .
    Flutimide
  • HY-A0027

    Histamine Receptor Phosphodiesterase (PDE) Inflammation/Immunology Endocrinology
    Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride can be used for the research of respiratory diseases .
    Fenspiride hydrochloride
  • HY-A0027A

    Histamine Receptor Phosphodiesterase (PDE) Inflammation/Immunology
    Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride can be used for the research of respiratory diseases .
    Fenspiride
  • HY-146356

    Adenylate Cyclase Inflammation/Immunology
    Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases .
    Adenylyl cyclase type 2 agonist-1
  • HY-14162

    FLAP Inflammation/Immunology
    AM103 (free acid) is a selective FLAP inhibitor that can block the first step of the LT pathway, which is 5-LO activation. AM103 (free acid) can inhibit the production of LTB4 and cysteinyl leukotrienes (CysLT). AM103 (free acid) has anti-inflammatory activity in a mouse model of chronic lung inflammation and can extend the survival time of mice injected with platelet-activating factor. AM103 (free acid) can be used for research on respiratory diseases such as asthma .
    AM103 free acid
  • HY-B1374S1

    (-)-Florfenicol-d3; SCH-25298-d3

    Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
    Florfenicol-d3
  • HY-123862

    PI3K Lipase G Protein-coupled Receptor Kinase (GRK) Inflammation/Immunology
    LAS195319 is an orally active and potent inhibitor against PI3Kδ with an IC50 value of 0.5 nM. LAS195319 is also a highly selective inhibitor against an extensive panel of proteins, lipid kinases and GPCRs. LAS195319 causes an inhibition of neutrophil and eosinophil infiltration. LAS195319 is promising for research of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) .
    LAS195319
  • HY-B0905A
    Tilmicosin phosphate
    2 Publications Verification

    LY-177370 phosphate; EL-870 phosphate

    Bacterial Antibiotic Infection
    Tilmicosin phosphate is a antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
    Tilmicosin phosphate
  • HY-B0905
    Tilmicosin
    2 Publications Verification

    LY-177370; EL-870

    Bacterial Antibiotic Infection
    Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
    Tilmicosin
  • HY-B0519A
    Tylosin
    1 Publications Verification

    Bacterial Antibiotic Infection
    Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
    Tylosin
  • HY-B0519B
    Tylosin phosphate
    1 Publications Verification

    Bacterial Antibiotic Infection
    Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
    Tylosin phosphate
  • HY-B0519
    Tylosin tartrate
    1 Publications Verification

    Bacterial Antibiotic Infection
    Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
    Tylosin tartrate
  • HY-145603

    VX-121

    CFTR Chloride Channel Neurological Disease
    Vanzacaftor (VX-121) is an orally active noval corrector of Cystic fibrosis transmembrane conductance regulator (CFTR). Vanzacaftor improves processing and trafficking of CFTR protein as well as increases chloride transport in triple combined with Tezacaftor (HY-15448) and Deutivacaftor. Vanzacaftor-Tezacaftor-Deutivacaftor is safe and well tolerated, improving lung function, respiratory symptoms, and CFTR function with cystic fibrosis, which is promising for research in the field of cystic fibrosis diseases .
    Vanzacaftor
  • HY-B0905S

    LY-177370-d3; EL-870-d3

    Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
    Tilmicosin-d3
  • HY-B0519AR

    Bacterial Antibiotic Infection
    Tylosin (Standard) is the analytical standard of Tylosin. This product is intended for research and analytical applications. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
    Tylosin (Standard)
  • HY-B0519BR

    Bacterial Antibiotic Infection
    Tylosin (phosphate) (Standard) is the analytical standard of Tylosin (phosphate). This product is intended for research and analytical applications. Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle .
    Tylosin phosphate (Standard)
  • HY-B0905R

    Bacterial Antibiotic Infection
    Tilmicosin (Standard) is the analytical standard of Tilmicosin. This product is intended for research and analytical applications. Tilmicosin is a macrolide antibiotic, is used for the research of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica.
    Tilmicosin (Standard)
  • HY-115876

    Btk Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    BTK-IN-5 is a covalent BTK inhibitor for researching medical conditions such as cardiovascular diseases, respiratory diseases, inflammation, and diabetes.
    BTK-IN-5
  • HY-118376

    Others Others
    Nestifylline is a biochemical reagent. Nestifylline can be used to study respiratory diseases such as bronchospasm .
    Nestifylline
  • HY-155944

    Phosphodiesterase (PDE) Inflammation/Immunology
    Isbufylline is a Phosphodiesterase inhibitor. Isbufylline is orally available. Isbufylline can be used in the research of respiratory diseases and inflammation such as asthma and pneumonia.
    Isbufylline
  • HY-B1096

    Ethamivan; N,N-Diethylvanillamide

    Others Neurological Disease
    Etamivan (Ethamivan), an orally active respiratory stimulant, is mainly used in the research of barbiturate overdose and chronic obstructive pulmonary disease .
    Etamivan
  • HY-U00382

    Neurokinin Receptor Neurological Disease Inflammation/Immunology
    Substance P Receptor Antagonist 1 has the potential function in central nervous system disorders, respiratory, inflammatory diseases and gastrointestinal disorders.
    Substance P Receptor Antagonist 1
  • HY-B0372

    Others Inflammation/Immunology
    Bromhexine is a potent expectorant. Bromhexine increase mucociliary clearance and reduces cough. Bromhexine can be used in study various respiratory diseases .
    Bromhexine
  • HY-108193

    Adenosine Receptor Inflammation/Immunology
    GW 328267 is an A2A receptor agonist. GW 328267 can be used for research of asthma, COPD and upper respiratory inflammatory disease .
    GW 328267
  • HY-161877

    RSV Infection
    GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease .
    GS-7682
  • HY-18260
    Bisphenol A
    5+ Cited Publications

    Endogenous Metabolite Endocrinology
    Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
    Bisphenol A
  • HY-119985

    Z 1170

    Adrenergic Receptor Others
    Broxaterol (Z 1170) is the an agonist of β2 adrenergic receptor that affects the smooth muscle receptors in the body. Broxaterol plays an important role in respiratory disease .
    Broxaterol
  • HY-B0035S

    Sulfadimidine-d4; Sulfadimerazine-d4

    Bacterial Infection
    Sulfamethazine-d4 is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].
    Sulfamethazine-d4
  • HY-12995

    FLAP Cardiovascular Disease Inflammation/Immunology
    BI 665915 is an orally active and potent 5-lipoxygenase-activating protein (FLAP) inhibitor. BI 665915 inhibits FLAP production that blocks LTB4 biosynthesis in mice. BI 665915 is promising for research of various inflammatory diseases, including respiratory and cardiovascular diseases .
    BI 665915
  • HY-P10093

    PI3K Others
    Penetratin-PI3Kγ(126-150) is a peptide inhibitor of ΡI3Κγ that plays an important role in respiratory system diseases .
    Penetratin-PI3Kγ(126-150)
  • HY-18260S1

    Endogenous Metabolite Endocrinology
    Bisphenol A-d6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].
    Bisphenol A-d6
  • HY-145390

    Keap1-Nrf2 Inflammation/Immunology
    Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) .
    Nrf2 activator-1
  • HY-18260S

    Endogenous Metabolite Endocrinology
    Bisphenol A-d16 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].
    Bisphenol A-d16

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