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  6. Histamine phosphate

Histamine phosphate  (Synonyms: Histamine diphosphate)

Cat. No.: HY-A0129 Purity: 99.99%
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Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase.

For research use only. We do not sell to patients.

Histamine phosphate Chemical Structure

Histamine phosphate Chemical Structure

CAS No. : 51-74-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
500 mg USD 50 In-stock
1 g USD 60 In-stock
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Based on 9 publication(s) in Google Scholar

Other Forms of Histamine phosphate:

Histamine phosphate Related Antibodies

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View All Histamine Receptor Isoform Specific Products:

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase.

Clinical Trial
Molecular Weight

307.14

Formula

C5H15N3O8P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NCCC1=CNC=N1.O=P(O)(O)O.O=P(O)(O)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (325.58 mM; Need ultrasonic)

DMSO : 1.43 mg/mL (4.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2558 mL 16.2792 mL 32.5584 mL
5 mM 0.6512 mL 3.2558 mL 6.5117 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (162.79 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.2558 mL 16.2792 mL 32.5584 mL 81.3961 mL
H2O 5 mM 0.6512 mL 3.2558 mL 6.5117 mL 16.2792 mL
10 mM 0.3256 mL 1.6279 mL 3.2558 mL 8.1396 mL
15 mM 0.2171 mL 1.0853 mL 2.1706 mL 5.4264 mL
20 mM 0.1628 mL 0.8140 mL 1.6279 mL 4.0698 mL
25 mM 0.1302 mL 0.6512 mL 1.3023 mL 3.2558 mL
30 mM 0.1085 mL 0.5426 mL 1.0853 mL 2.7132 mL
40 mM 0.0814 mL 0.4070 mL 0.8140 mL 2.0349 mL
50 mM 0.0651 mL 0.3256 mL 0.6512 mL 1.6279 mL
60 mM 0.0543 mL 0.2713 mL 0.5426 mL 1.3566 mL
80 mM 0.0407 mL 0.2035 mL 0.4070 mL 1.0175 mL
100 mM 0.0326 mL 0.1628 mL 0.3256 mL 0.8140 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Histamine phosphate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Histamine51-74-1Histamine diphosphateHistamine ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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