2. Gene
  3. KIF9 - kinesin family member 9 Gene

KIF9 - kinesin family member 9 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 64147 | Gene type: protein coding

About KIF9

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:47,227,998-47,282,799 (from NCBI)

This gene has 13 transcripts (splice variants), 160 orthologues and 41 paralogues. Biased expression in testis (RPKM 11.7), thyroid (RPKM 1.7) and 10 other tissues.

Summary

Enables identical protein binding activity. Involved in extracellular matrix disassembly; organelle disassembly; and regulation of podosome assembly. Located in microtubule; podosome; and vesicle. [provided by Alliance of Genome Resources, Apr 2022]

KIF9 Products(9)

mRNA Protein Name
NM_001134878.3 NP_001128350.1 kinesin-like protein KIF9 isoform 2
NM_001377474.1 NP_001364403.1 kinesin-like protein KIF9 isoform 3
NM_001377475.1 NP_001364404.1 kinesin-like protein KIF9 isoform 4
NM_001377476.1 NP_001364405.1 kinesin-like protein KIF9 isoform 5
NM_001377477.1 NP_001364406.1 kinesin-like protein KIF9 isoform 5
NM_001413975.1 NP_001400904.1 kinesin-like protein KIF9 isoform 6
NM_001413976.1 NP_001400905.1 kinesin-like protein KIF9 isoform 7
NM_022342.6 NP_071737.1 kinesin-like protein KIF9 isoform 1
NM_182902.4 NP_878905.2 kinesin-like protein KIF9 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
21119006 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21119006 GOA
Biological Process GO Annotation Evidence Reference Source
involved in extracellular matrix disassembly IMP
IMP: Inferred from mutant phenotype
21119006 GOA
involved in organelle disassembly IMP
IMP: Inferred from mutant phenotype
21119006 GOA
involved in regulation of podosome assembly IMP
IMP: Inferred from mutant phenotype
21119006 GOA
Cellular Component GO Annotation Evidence Reference Source
located in microtubule IDA
IDA: Inferred from direct assay
21119006 GOA
located in podosome IDA
IDA: Inferred from direct assay
21119006 GOA
located in vesicle IDA
IDA: Inferred from direct assay
21119006 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KIF9 Protein Structure

Kinesin

Kinesin: Kinesin motor domain (29 - 339)

  • 0
  • 200
  • 400
  • 600
  • 790 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF9

kinesin protein 9

KIF9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
KIF9 Q9HAQ2 PNMA5 Homo sapiens Q96PV4
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PNMA5 Homo sapiens Q96PV4
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZNF572 Homo sapiens Q7Z3I7
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZNF572 Homo sapiens Q7Z3I7
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 SLAIN1 Homo sapiens Q8ND83
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 SLAIN1 Homo sapiens Q8ND83
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 INKA1 Homo sapiens Q96EL1
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 INKA1 Homo sapiens Q96EL1
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 STEEP1 Homo sapiens Q9H5V9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 STEEP1 Homo sapiens Q9H5V9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PPP1R13B Homo sapiens Q96KQ4
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 GOLGA6A Homo sapiens Q9NYA3
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 GOLGA6A Homo sapiens Q9NYA3
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 GOLGA6A Homo sapiens Q9NYA3
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 IQCB1 Homo sapiens Q15051-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 IQCB1 Homo sapiens Q15051-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 CCDC125 Homo sapiens Q86Z20
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 CCDC125 Homo sapiens Q86Z20
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 KRTAP10-6 Homo sapiens P60371
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 KRTAP10-6 Homo sapiens P60371
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 SHISA6 Homo sapiens Q6ZSJ9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 SHISA6 Homo sapiens Q6ZSJ9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZC2HC1C Homo sapiens Q53FD0-2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZC2HC1C Homo sapiens Q53FD0-2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 OOEP Homo sapiens A6NGQ2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 OOEP Homo sapiens A6NGQ2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 MID1 Homo sapiens O15344
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 MID1 Homo sapiens O15344
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PRICKLE1 Homo sapiens Q96MT3
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 PRICKLE1 Homo sapiens Q96MT3
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 HMBOX1 Homo sapiens Q6NT76
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZNF566 Homo sapiens Q969W8
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZNF566 Homo sapiens Q969W8
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 KANK2 Homo sapiens Q63ZY3
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 KANK2 Homo sapiens Q63ZY3
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 VIM Homo sapiens P08670
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 VIM Homo sapiens P08670
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ALAS1 Homo sapiens P13196
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ALAS1 Homo sapiens P13196
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 KCTD9 Homo sapiens Q7L273
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 KCTD9 Homo sapiens Q7L273
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 RBM48 Homo sapiens Q5RL73
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 RBM48 Homo sapiens Q5RL73
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 EMD Homo sapiens P50402
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 EMD Homo sapiens P50402
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 OIP5 Homo sapiens O43482
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 OIP5 Homo sapiens O43482
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ATP5IF1 Homo sapiens Q9UII2
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 ATP5IF1 Homo sapiens Q9UII2
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ATP5IF1 Homo sapiens Q9UII2
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZCCHC7 Homo sapiens Q8N3Z6
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZCCHC7 Homo sapiens Q8N3Z6
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZNF417 Homo sapiens Q8TAU3
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 MAD1L1 Homo sapiens Q9Y6D9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 MAD1L1 Homo sapiens Q9Y6D9
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 MAD1L1 Homo sapiens Q9Y6D9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 AMOTL2 Homo sapiens Q9Y2J4
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 AMOTL2 Homo sapiens Q9Y2J4
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 AMOTL2 Homo sapiens Q9Y2J4
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra
KIF9 Q9HAQ2 ZNF436 Homo sapiens Q9C0F3
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 ZNF436 Homo sapiens Q9C0F3
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 IHO1 Homo sapiens Q8IYA8
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 NAB2 Homo sapiens Q15742
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 NAB2 Homo sapiens Q15742
Y2H Prey Pooling
32296183
Intra
KIF9 Q9HAQ2 PRMT6 Homo sapiens Q96LA8
Y2H
23455924
Intra
KIF9 Q9HAQ2 CYTIP Homo sapiens O60759
Y2H Array
32296183
Intra
KIF9 Q9HAQ2 CYTIP Homo sapiens O60759
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Megabladder, Congenital

MGBL

Congenital Megabladder
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07296 KIF9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF9 VGNC VGNC:42412
Macaca mulatta KIF9 VGNC VGNC:84157
Felis catus KIF9 VGNC VGNC:63119
Bos taurus KIF9 VGNC VGNC:30609
Rattus norvegicus KIF9 RGD RGD:1565187
Mus musculus KIF9 MGD MGI:1098237