1. Gene
  2. KCTD9 - potassium channel tetramerization domain containing 9 Gene

KCTD9 - potassium channel tetramerization domain containing 9 Gene

Homo sapiens

Also known as BTBD27

Gene ID: 54793 | Gene type: protein coding

About KCTD9

Cytogenetic location: 8p21.2 Genomic coordinates (GRCh38): 8:25,427,847-25,458,433 (from NCBI)

This gene has 11 transcripts (splice variants), 266 orthologues and 3 paralogues. Ubiquitous expression in heart (RPKM 8.3), esophagus (RPKM 7.8) and 25 other tissues.

Summary

Enables cullin family protein binding activity; identical protein binding activity; and protein self-association. Predicted to be involved in intracellular signal transduction; protein homooligomerization; and protein ubiquitination. [provided by Alliance of Genome Resources, Apr 2022]

KCTD9 Products(1)

mRNA Protein Name
NM_017634.4 NP_060104.2 BTB/POZ domain-containing protein KCTD9
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables cullin family protein binding IDA
IDA: Inferred from direct assay
26334369 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
21516116 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21145461 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

KCTD9 Protein Structure

KHA

KHA: KHA, dimerisation domain of potassium ion channel (1 - 64)

BTB_2

BTB_2: BTB/POZ domain (91 - 182)

Pentapeptide

Pentapeptide: Pentapeptide repeats (8 copies) (248 - 279)

Pentapeptide

Pentapeptide: Pentapeptide repeats (8 copies) (338 - 376)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
Protein Preferred Names Protein Names

BTB/POZ domain-containing protein KCTD9

potassium channel tetramerisation domain containing 9

KCTD9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
KCTD9 Q7L273 TASOR2 Homo sapiens Q5VWN6-2 25416956
Intra
KCTD9 Q7L273 TASOR2 Homo sapiens Q5VWN6-2 25416956
Intra
KCTD9 Q7L273 ADAMTSL4 Homo sapiens Q6UY14-3 32296183
Intra
KCTD9 Q7L273 ADAMTSL4 Homo sapiens Q6UY14-3 32296183
Intra
KCTD9 Q7L273 SPMIP4 Homo sapiens Q8N865 32296183
Intra
KCTD9 Q7L273 SPMIP4 Homo sapiens Q8N865 32296183
Intra
KCTD9 Q7L273 SPMIP4 Homo sapiens Q8N865 32296183
Intra
KCTD9 Q7L273 KRTAP13-3 Homo sapiens Q3SY46 32296183
Intra
KCTD9 Q7L273 KRTAP13-3 Homo sapiens Q3SY46 32296183
Intra
KCTD9 Q7L273 SYT6 Homo sapiens Q5T7P8-2 25416956
Intra
KCTD9 Q7L273 SYT6 Homo sapiens Q5T7P8-2 25416956
Intra
KCTD9 Q7L273 SPMIP6 Homo sapiens Q8NCR6 32296183
Intra
KCTD9 Q7L273 SPMIP6 Homo sapiens Q8NCR6 32296183
Intra
KCTD9 Q7L273 SPMIP6 Homo sapiens Q8NCR6 32296183
Intra
KCTD9 Q7L273 SLAIN1 Homo sapiens Q8ND83 32296183
Intra
KCTD9 Q7L273 SLAIN1 Homo sapiens Q8ND83 32296183
Intra
KCTD9 Q7L273 SLAIN1 Homo sapiens Q8ND83 32296183
Intra
KCTD9 Q7L273 PPP1R16B Homo sapiens Q96T49 25416956
Intra
KCTD9 Q7L273 PPP1R16B Homo sapiens Q96T49 25416956
Intra
KCTD9 Q7L273 KRT34 Homo sapiens O76011 32296183
Intra
KCTD9 Q7L273 KRT34 Homo sapiens O76011 32296183
Intra
KCTD9 Q7L273 KRT35 Homo sapiens Q92764 32296183
Intra
KCTD9 Q7L273 KRT35 Homo sapiens Q92764 32296183
Intra
KCTD9 Q7L273 KRT35 Homo sapiens Q92764 32296183
Intra
KCTD9 Q7L273 TEPSIN Homo sapiens Q96N21 32296183
Intra
KCTD9 Q7L273 TEPSIN Homo sapiens Q96N21 32296183
Intra
KCTD9 Q7L273 TEPSIN Homo sapiens Q96N21 32296183
Intra
KCTD9 Q7L273 GOLGA6A Homo sapiens Q9NYA3 32296183
Intra
KCTD9 Q7L273 GOLGA6A Homo sapiens Q9NYA3 32296183
Intra
KCTD9 Q7L273 GOLGA6A Homo sapiens Q9NYA3 32296183
Intra
KCTD9 Q7L273 PRDM6 Homo sapiens Q9NQX0 32296183
Intra
KCTD9 Q7L273 PRDM6 Homo sapiens Q9NQX0 32296183
Intra
KCTD9 Q7L273 PRDM6 Homo sapiens Q9NQX0 32296183
Intra
KCTD9 Q7L273 BANP Homo sapiens Q8N9N5-2 32296183
Intra
KCTD9 Q7L273 BANP Homo sapiens Q8N9N5-2 32296183
Intra
KCTD9 Q7L273 BANP Homo sapiens Q8N9N5-2 32296183
Intra
KCTD9 Q7L273 KRTAP13-2 Homo sapiens Q52LG2 32296183
Intra
KCTD9 Q7L273 KRTAP13-2 Homo sapiens Q52LG2 32296183
Intra
KCTD9 Q7L273 IGFN1 Homo sapiens Q86VF2-5 32296183
Intra
KCTD9 Q7L273 USP54 Homo sapiens Q70EL1-9 32296183
Intra
KCTD9 Q7L273 USP54 Homo sapiens Q70EL1-9 32296183
Intra
KCTD9 Q7L273 ACTMAP Homo sapiens Q5BKX5-3 32296183
Intra
KCTD9 Q7L273 ACTMAP Homo sapiens Q5BKX5-3 32296183
Intra
KCTD9 Q7L273 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
KCTD9 Q7L273 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
KCTD9 Q7L273 POF1B Homo sapiens Q8WVV4-1 32296183
Intra
KCTD9 Q7L273 SAXO4 Homo sapiens Q7Z5V6-2 32296183
Intra
KCTD9 Q7L273 SAXO4 Homo sapiens Q7Z5V6-2 32296183
Intra
KCTD9 Q7L273 SAXO4 Homo sapiens Q7Z5V6-2 32296183
Intra
KCTD9 Q7L273 SMUG1 Homo sapiens Q53HV7-2 32296183
Intra
KCTD9 Q7L273 SMUG1 Homo sapiens Q53HV7-2 32296183
Intra
KCTD9 Q7L273 ZBTB42 Homo sapiens B2RXF5 32296183
Intra
KCTD9 Q7L273 ZBTB42 Homo sapiens B2RXF5 32296183
Intra
KCTD9 Q7L273 NDUFAB1 Homo sapiens O14561 32296183
Intra
KCTD9 Q7L273 NDUFAB1 Homo sapiens O14561 32296183
Intra
KCTD9 Q7L273 MBD3L1 Homo sapiens Q8WWY6 32296183
Intra
KCTD9 Q7L273 MBD3L1 Homo sapiens Q8WWY6 32296183
Intra
KCTD9 Q7L273 MBD3L1 Homo sapiens Q8WWY6 32296183
Intra
KCTD9 Q7L273 UNKL Homo sapiens Q9H9P5-5 32296183
Intra
KCTD9 Q7L273 UNKL Homo sapiens Q9H9P5-5 32296183
Intra
KCTD9 Q7L273 UNKL Homo sapiens Q9H9P5-5 32296183
Intra
KCTD9 Q7L273 MEOX2 Homo sapiens Q6FHY5 32296183
Intra
KCTD9 Q7L273 MEOX2 Homo sapiens Q6FHY5 32296183
Intra
KCTD9 Q7L273 EHHADH Homo sapiens Q08426 25416956
Intra
KCTD9 Q7L273 EHHADH Homo sapiens Q08426 25416956
Intra
KCTD9 Q7L273 EHHADH Homo sapiens Q08426 31515488
Intra
KCTD9 Q7L273 LONRF1 Homo sapiens Q17RB8 25416956
Intra
KCTD9 Q7L273 LONRF1 Homo sapiens Q17RB8 25416956
Intra
KCTD9 Q7L273 LONRF1 Homo sapiens Q17RB8 25416956
Intra
KCTD9 Q7L273 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
KCTD9 Q7L273 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
KCTD9 Q7L273 BLZF1 Homo sapiens Q9H2G9 32296183
Intra
KCTD9 Q7L273 PPP1R18 Homo sapiens Q6NYC8 25416956
Intra
KCTD9 Q7L273 MIIP Homo sapiens Q5JXC2 32296183
Intra
KCTD9 Q7L273 MIIP Homo sapiens Q5JXC2 32296183
Intra
KCTD9 Q7L273 CDPF1 Homo sapiens Q6NVV7 32296183
Intra
KCTD9 Q7L273 CDPF1 Homo sapiens Q6NVV7 32296183
Intra
KCTD9 Q7L273 ZNF408 Homo sapiens Q9H9D4 32296183
Intra
KCTD9 Q7L273 PFDN5 Homo sapiens Q99471 32296183
Intra
KCTD9 Q7L273 PFDN5 Homo sapiens Q99471 32296183
Intra
KCTD9 Q7L273 PFDN5 Homo sapiens Q99471 32296183
Intra
KCTD9 Q7L273 PSMB2 Homo sapiens P49721 25416956
Intra
KCTD9 Q7L273 PSMA1 Homo sapiens P25786 25416956
Intra
KCTD9 Q7L273 PSMA1 Homo sapiens P25786 32296183
Intra
KCTD9 Q7L273 PSMA1 Homo sapiens P25786 32296183
Intra
KCTD9 Q7L273 USP21 Homo sapiens Q9UK80 32296183
Intra
KCTD9 Q7L273 SPATS1 Homo sapiens Q496A3 32296183
Intra
KCTD9 Q7L273 SPATS1 Homo sapiens Q496A3 32296183
Intra
KCTD9 Q7L273 ZNF620 Homo sapiens Q6ZNG0 32296183
Intra
KCTD9 Q7L273 ZNF620 Homo sapiens Q6ZNG0 32296183
Intra
KCTD9 Q7L273 NUP35 Homo sapiens Q8NFH5 25416956
Intra
KCTD9 Q7L273 GORASP2 Homo sapiens Q9H8Y8 25416956
Intra
KCTD9 Q7L273 NUP35 Homo sapiens Q8NFH5 32296183
Intra
KCTD9 Q7L273 CUL3 Homo sapiens Q13618 33961781
Intra
KCTD9 Q7L273 NUP35 Homo sapiens Q8NFH5 32296183
Intra
KCTD9 Q7L273 GORASP2 Homo sapiens Q9H8Y8 29892012
Intra
KCTD9 Q7L273 NUP35 Homo sapiens Q8NFH5 32296183
Intra
KCTD9 Q7L273 CRADD Homo sapiens P78560 25416956
Intra
KCTD9 Q7L273 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
KCTD9 Q7L273 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
KCTD9 Q7L273 TRIM42 Homo sapiens Q8IWZ5 25416956
Intra
KCTD9 Q7L273 TRIM42 Homo sapiens Q8IWZ5 32296183
Intra
KCTD9 Q7L273 GOLGA6L9 Homo sapiens A6NEM1 32296183
Intra
KCTD9 Q7L273 GOLGA6L9 Homo sapiens A6NEM1 32296183
Intra
KCTD9 Q7L273 EPM2AIP1 Homo sapiens Q7L775 32296183
Intra
KCTD9 Q7L273 RUSC1 Homo sapiens Q9BVN2 32296183
Intra
KCTD9 Q7L273 RUSC1 Homo sapiens Q9BVN2 32296183
Intra
KCTD9 Q7L273 RUSC1 Homo sapiens Q9BVN2 32296183
Intra
KCTD9 Q7L273 INCA1 Homo sapiens Q0VD86 32296183
Intra
KCTD9 Q7L273 INCA1 Homo sapiens Q0VD86 32296183
Intra
KCTD9 Q7L273 CBX8 Homo sapiens Q9HC52 32296183
Intra
KCTD9 Q7L273 CBX8 Homo sapiens Q9HC52 25416956
Intra
KCTD9 Q7L273 CBX8 Homo sapiens Q9HC52 25416956
Intra
KCTD9 Q7L273 STX11 Homo sapiens O75558 25416956
Intra
KCTD9 Q7L273 STX11 Homo sapiens O75558 25416956
Intra
KCTD9 Q7L273 TRIM27 Homo sapiens P14373 32296183
Intra
KCTD9 Q7L273 TRIM27 Homo sapiens P14373 32296183
Intra
KCTD9 Q7L273 KLHL26 Homo sapiens Q53HC5 32296183
Intra
KCTD9 Q7L273 KLHL26 Homo sapiens Q53HC5 32296183
Intra
KCTD9 Q7L273 SDCBP Homo sapiens O00560 25416956
Intra
KCTD9 Q7L273 GORASP2 Homo sapiens Q9H8Y8 32296183
Intra
KCTD9 Q7L273 LNX1 Homo sapiens Q8TBB1 32296183
Intra
KCTD9 Q7L273 LNX1 Homo sapiens Q8TBB1 32296183
Intra
KCTD9 Q7L273 LNX1 Homo sapiens Q8TBB1 32296183
Intra
KCTD9 Q7L273 RBPMS Homo sapiens Q93062 25416956
Intra
KCTD9 Q7L273 RBPMS Homo sapiens Q93062 25416956
Intra
KCTD9 Q7L273 RBPMS Homo sapiens Q93062 25416956
Intra
KCTD9 Q7L273 HOXA1 Homo sapiens P49639 32296183
Intra
KCTD9 Q7L273 HOXA1 Homo sapiens P49639 32296183
Intra
KCTD9 Q7L273 NIF3L1 Homo sapiens Q9GZT8 32296183
Intra
KCTD9 Q7L273 NTAQ1 Homo sapiens Q96HA8 32296183
Intra
KCTD9 Q7L273 FAM124B Homo sapiens Q9H5Z6 25416956
Intra
KCTD9 Q7L273 FAM124B Homo sapiens Q9H5Z6 25416956
Intra
KCTD9 Q7L273 FAM124B Homo sapiens Q9H5Z6 25416956
Intra
KCTD9 Q7L273 DDIT4L Homo sapiens Q96D03 32296183
Intra
KCTD9 Q7L273 DDIT4L Homo sapiens Q96D03 32296183
Intra
KCTD9 Q7L273 DDIT4L Homo sapiens Q96D03 32296183
Intra
KCTD9 Q7L273 TRIP6 Homo sapiens Q15654 32296183
Intra
KCTD9 Q7L273 TRIP6 Homo sapiens Q15654 32296183
Intra
KCTD9 Q7L273 SPG21 Homo sapiens Q9NZD8 32296183
Intra
KCTD9 Q7L273 TRIM32 Homo sapiens Q13049 25416956
Intra
KCTD9 Q7L273 TRIM32 Homo sapiens Q13049 32296183
Intra
KCTD9 Q7L273 TRIM32 Homo sapiens Q13049 32296183
Intra
KCTD9 Q7L273 ZNF426 Homo sapiens Q9BUY5 32296183
Intra
KCTD9 Q7L273 ZNF426 Homo sapiens Q9BUY5 32296183
Intra
KCTD9 Q7L273 ZNF426 Homo sapiens Q9BUY5 32296183
Intra
KCTD9 Q7L273 SPMIP9 Homo sapiens Q96LM6 32296183
Intra
KCTD9 Q7L273 SPMIP9 Homo sapiens Q96LM6 32296183
Intra
KCTD9 Q7L273 SPMIP9 Homo sapiens Q96LM6 32296183
Intra
KCTD9 Q7L273 GEM Homo sapiens P55040 25416956
Intra
KCTD9 Q7L273 GEM Homo sapiens P55040 25416956
Intra
KCTD9 Q7L273 AQP1 Homo sapiens P29972 25416956
Intra
KCTD9 Q7L273 AQP1 Homo sapiens P29972 25416956
Intra
KCTD9 Q7L273 AQP1 Homo sapiens P29972 25416956
Intra
KCTD9 Q7L273 TASOR2 Homo sapiens Q5VWN6 32296183
Intra
KCTD9 Q7L273 TASOR2 Homo sapiens Q5VWN6 32296183
Intra
KCTD9 Q7L273 RFX6 Homo sapiens Q8HWS3 32296183
Intra
KCTD9 Q7L273 RFX6 Homo sapiens Q8HWS3 32296183
Intra
KCTD9 Q7L273 RFX6 Homo sapiens Q8HWS3 32296183
Intra
KCTD9 Q7L273 PNKD Homo sapiens Q8N490 25416956
Intra
KCTD9 Q7L273 PNKD Homo sapiens Q8N490 25416956
Intra
KCTD9 Q7L273 DEUP1 Homo sapiens Q05D60 32296183
Intra
KCTD9 Q7L273 DEUP1 Homo sapiens Q05D60 32296183
Intra
KCTD9 Q7L273 CARD9 Homo sapiens Q9H257 25416956
Intra
KCTD9 Q7L273 WDR83 Homo sapiens Q9BRX9 32296183
Intra
KCTD9 Q7L273 WDR83 Homo sapiens Q9BRX9 32296183
Intra
KCTD9 Q7L273 WDR83 Homo sapiens Q9BRX9 32296183
Intra
KCTD9 Q7L273 MAD2L2 Homo sapiens Q9UI95 25416956
Intra
KCTD9 Q7L273 MAD2L2 Homo sapiens Q9UI95 25416956
Intra
KCTD9 Q7L273 PICK1 Homo sapiens Q9NRD5 32296183
Intra
KCTD9 Q7L273 KIF9 Homo sapiens Q9HAQ2 32296183
Intra
KCTD9 Q7L273 CFP Homo sapiens P27918 32296183
Intra
KCTD9 Q7L273 CFP Homo sapiens P27918 32296183
Intra
KCTD9 Q7L273 KRT31 Homo sapiens Q15323 32296183
Intra
KCTD9 Q7L273 KRT31 Homo sapiens Q15323 32296183
Intra
KCTD9 Q7L273 ARID5A Homo sapiens Q03989 32296183
Intra
KCTD9 Q7L273 ARID5A Homo sapiens Q03989 32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

KCTD9 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83393 KCTD9 Antibody (YA3138) WB, ICC/IF Human

Related Diseases

Diseases Alias
Progressive Myoclonus Epilepsy 3

Cln14 Disease

Epm3

Neuronal Ceroid Lipofuscinosis 14

Pme Type 3

Progressive Myoclonic Epilepsy Due To Kctd7 Deficiency

Progressive Myoclonus Epilepsy Type 3

Epilepsy, Progressive Myoclonic 3

Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome

Sen Syndrome

SENS

Scalp Ear Nipple Syndrome

Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples

Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples

Indian Childhood Cirrhosis

Progressive Myoclonus Epilepsy

Pme

Progressive Myoclonic Epilepsy

Myoclonic Epilepsies, Progressive

Unverricht-Lundborg Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus KCTD9 RGD RGD:1312010
Canis familiaris KCTD9 VGNC VGNC:42312
Bos taurus KCTD9 VGNC VGNC:30516
Felis catus KCTD9 VGNC VGNC:63065
Macaca mulatta KCTD9 VGNC VGNC:84009
Mus musculus KCTD9 MGD MGI:2145579