Search Result
Results for "
Anaerobic
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
16
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B0177
-
-
-
- HY-126129
-
|
Bacterial
|
Infection
|
Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .
|
-
-
- HY-144300
-
TNP-2198
|
Bacterial
|
Infection
|
Rifasutenizol (TNP-2198) is a dual-targeted antibacterial agent that has a good antibacterial effect on Helicobacter pylori infection. Rifasutenizol can be used in the study of microaerophilic and anaerobic bacterial infections .
|
-
-
- HY-13625
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L-749345; MK-826
|
Bacterial
Antibiotic
|
Infection
Cancer
|
Ertapenem sodium (L-749345) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
-
- HY-N8461
-
3-Hydroxypropionaldehyde; 3-Hydroxypropanal
|
Bacterial
|
Infection
|
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates .
|
-
-
- HY-130338
-
-
-
- HY-130339
-
-
-
- HY-119614
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BA-32644
|
Parasite
Bacterial
|
Infection
|
Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC50 values ranging from 0.0037 to 1.0 μg/mL .
|
-
-
- HY-138094
-
|
Drug Metabolite
|
Infection
|
N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
|
-
-
- HY-125496
-
|
Antibiotic
Bacterial
|
Infection
|
A201A is a aminoacylnucleoside antibiotic with antibacterial activities. A201A is highly effective against Gram-positive and most Gram-negative anaerobic bacteria. A201A inhibits tRNA accommodation during translation .
|
-
-
- HY-A0294
-
MK-0826
|
Antibiotic
Bacterial
|
Infection
|
Ertapenem (MK-0826) is a broad spectrum and long acting β-lactam antibiotic. Ertapenem has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
-
- HY-135024
-
Phenylacetyl Coenzyme A
|
Endogenous Metabolite
|
Metabolic Disease
|
Phenylacetyl CoA is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .
|
-
-
- HY-B0318
-
-
-
- HY-117778
-
|
Enolase
Bacterial
Antibiotic
|
Infection
Cancer
|
SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions .
|
-
-
- HY-A0294A
-
MK-0826 disodium
|
Bacterial
Antibiotic
|
Infection
|
Ertapenem (MK-0826) disodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem disodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem disodium can be used for the research of severe infections caused by bacteria in the skin, lungs, stomach, pelvis, and urinary tract .
|
-
-
- HY-126129R
-
|
Drug Metabolite
Bacterial
|
Infection
|
Desacetylcefotaxime (Standard) is the analytical standard of Desacetylcefotaxime. This product is intended for research and analytical applications. Desacetylcefotaxime, the in vivo metabolite of Cefotaxime (CTX), possesses significant in vitro antimicrobial activity similar to the parent compound against a variety of aerobic and anaerobic bacteria .
|
-
-
- HY-118906
-
|
Antibiotic
Bacterial
|
Infection
|
BO-1165 is an antibiotic with good antibacterial activity against Gram-negative bacteria, but almost no activity against Gram-positive bacteria and anaerobic bacteria. BO-1165 has high antibacterial activity against Pseudomonas aeruginosa (MIC50=3.12 mg/L) and P. cepacia (MIC50=1.56 mg/L) .
|
-
-
- HY-B0536
-
AM-1091; CI-960; PD 127391
|
Bacterial
Antibiotic
|
Infection
|
Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
-
- HY-B0536A
-
AM 1091 hydrochloride; CI 960 hydrochloride; PD127391 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
Clinafloxacin hydrochloride (AM 1091 hydrochloride) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin hydrochloride is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
-
- HY-B0318A
-
SC 326421
|
Antibiotic
Bacterial
Parasite
Apoptosis
|
Infection
Inflammation/Immunology
|
Metronidazole hydrochloride (SC 326421) is an orally active nitroimidazole antibiotic, can be used to research anaerobic infections. Metronidazole hydrochloride can cross blood brain barrier and results inflammation and skeletal muscle contraction under long-term application .
|
-
-
- HY-B0318R
-
|
Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
Inflammation/Immunology
Cancer
|
Metronidazole (Standard) is the analytical standard of Metronidazole. This product is intended for research and analytical applications. Metronidazole is an orally active nitroimidazole antibiotic. Metronidazole can cross blood brain barrier. Metronidazole can be used for the research of anaerobic infections .
|
-
-
- HY-B0159
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Q-35
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-B0159A
-
Q-35 dihydrate
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-B0536R
-
|
Bacterial
Antibiotic
|
Infection
|
Clinafloxacin (Standard) is the analytical standard of Clinafloxacin. This product is intended for research and analytical applications. Clinafloxacin (AM 1091) is a potent and broad-spectrum fluoroquinolone antibiotic, has inhibitory activity against gram-positive, gram-negative bacterias, and anaerobic pathogens in vitro . Clinafloxacin is against DNA gyrase and topoisomerase IV of S. aureus with IC50 values of 0.92 µg/ml and 1.62 µg/ml, respectively .
|
-
-
- HY-125919
-
-
-
- HY-B0159R
-
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-B1118
-
RP-14539; PM-185184
|
Parasite
Antibiotic
Bacterial
|
Infection
|
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
-
- HY-B1118A
-
RP-14539 hemihydrate; PM-185184 hemihydrate
|
Antibiotic
Bacterial
Parasite
|
Infection
|
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
-
- HY-B1118R
-
|
Parasite
Antibiotic
Bacterial
|
Infection
|
Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .
|
-
-
- HY-18716
-
-
-
- HY-12687
-
TIZ
|
Bacterial
HIV
Autophagy
Parasite
IKK
Influenza Virus
|
Infection
Cancer
|
Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .
|
-
-
- HY-B0239
-
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
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- HY-126570
-
Coloradocin
|
Antibiotic
Bacterial
|
Infection
|
Luminamicin (Coloradocin) is an antibiotic isolated from the culture broth of the actinomycete strain OMR-59. Luminamicin exhibits antimicrobial activity against anaerobic bacteria, particularly those belonging to the genus Clostridium. Luminamicin can be utilized in research concerning anaerobic bacteria .
|
-
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- HY-B0239R
-
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
-
- HY-130755
-
CHCoA; Cyclohexanecarboxyl-CoA; Cyclohexanoyl CoA
|
Others
|
Others
|
Cyclohexanoyl coenzyme A is the active form of cyclohexane carboxylic acid (CHC) from anaerobic degradation in Rhodopseudomonas palustris .
|
-
-
- HY-B0508
-
-
-
- HY-100306
-
|
Bacterial
|
Infection
|
PNU-176798 is an antimicrobial agent, targeting protein synthesis in a wide spectrum of gram-positive and anaerobic bacteria.
|
-
-
- HY-130069
-
-
-
- HY-B0318S1
-
-
-
- HY-14865C
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PTK0796 hydrochloride; Amadacycline hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
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- HY-14865
-
PTK 0796; Amadacycline
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-14865A
-
PTK 0796 mesylate; Amadacycline mesylate
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-14865B
-
PTK 0796 tosylate; Amadacycline tosylate
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-N0537
-
Xylose
2 Publications Verification
D-(+)-Xylose; (+)-Xylose; Wood sugar
|
Endogenous Metabolite
|
Others
|
D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.
|
-
-
- HY-N7102
-
|
Bacterial
Antibiotic
|
Infection
|
Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
-
- HY-B0026
-
|
Bacterial
Antibiotic
|
Infection
|
Ceftiofur hydrochloride is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
-
- HY-E70276
-
-
-
- HY-N0420S
-
Wormwood acid-d6
|
Endogenous Metabolite
|
Metabolic Disease
|
Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
|
-
-
- HY-14865BR
-
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-14865R
-
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-18715
-
(S)-Ornidazole; Levornidazole
|
Bacterial
Parasite
|
Infection
|
Ornidazole Levo- is the levo-isomer of Ornidazole. Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Ornidazole Levo- is the less active isomer.
|
-
- HY-115249
-
|
Bacterial
Parasite
Antibiotic
|
Infection
|
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-E70236
-
-
- HY-B0898
-
sodium ceftiofur
|
Bacterial
Antibiotic
|
Infection
|
Ceftiofur sodium (sodium ceftiofur) is a semisynthetic antibiotic with antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, aerobic and anaerobic, targeting livestock .
|
-
- HY-B0177S
-
|
Bacterial
|
Infection
|
Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa[1].
|
-
- HY-N0420S1
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Succinic-2,2,3,3-d4 acid is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
|
-
- HY-B0318S
-
|
Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
|
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
|
-
- HY-135024A
-
Phenylacetyl Coenzyme A lithium
|
Endogenous Metabolite
|
Metabolic Disease
|
Phenylacetyl CoA lithium (Phenylacetyl Coenzyme A lithium) is an acceptor oxidoreductase. Phenylacetyl CoA is a membrane-bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica .
|
-
- HY-B0177R
-
|
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Tinidazole (Standard) is the analytical standard of Tinidazole. This product is intended for research and analytical applications. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa .
|
-
- HY-W748013
-
|
Antibiotic
Bacterial
|
Infection
|
Cervinomycin A2 is an anti-anaerobic antibiotic that can be isolated from Streptomyces cervicalis. Cervinomycin A2 has a strong inhibitory effect on Clostridium perfringens, Gastrococcus prophylacticus, and Bacteroides fragilis .
|
-
- HY-106950
-
Diphosphofructose; Esafosfan; FDP
|
Endogenous Metabolite
|
Cardiovascular Disease
|
Fosfructose (Diphosphofructose;Esafosfan;FDP) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.
|
-
- HY-116228
-
Caderofloxacin; CS-940
|
Bacterial
|
Infection
|
Cadrofloxacin (Caderofloxacin; CS-940), a orally active fluoroquinolone, is effective against aerobic/anaerobic Gram-positive and Gram-negative bacteria. Cadrofloxacin can be used for the research of infectious diseases .
|
-
- HY-B1484
-
Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases .
|
-
- HY-B0508S1
-
-
- HY-B1484A
-
Latamoxef; Lamoxactam; LY-127935
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Moxalactam (Latamoxef) is a synthetic oxa-β-lactam antibiotic. Moxalactam has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam inhibits production of β-lactamases .
|
-
- HY-W004260B
-
Glycerol diarachidate
|
Endogenous Metabolite
Biochemical Assay Reagents
|
Others
|
Dieicosanoin is a diacylglycerol containing arachidic acid (HY-W004260). Arachidic acid is a saturated long-chain fatty acid with a 20-carbon backbone. Arachidic acid can be isolated from peanut butter and anaerobic fungi .
|
-
- HY-N0537R
-
|
Endogenous Metabolite
|
Others
|
Xylose (Standard) is the analytical standard of Xylose. This product is intended for research and analytical applications. D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.
|
-
- HY-N7102R
-
|
Bacterial
Antibiotic
|
Infection
|
Ceftiofur (Standard) is the analytical standard of Ceftiofur. This product is intended for research and analytical applications. Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive and gram-negative, aerobic and anaerobic bacteria encountered by domestic animals .
|
-
- HY-B1825
-
|
Antibiotic
Bacterial
|
Infection
Cancer
|
Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
|
-
- HY-P2800
-
|
Endogenous Metabolite
|
Others
|
Diaphorase, Recombinant microorganisms can be obtained from anaerobic sludge organisms. Diaphorase catalyzes biotransformation of hexahydro-1,3, 5-trinitro-1,3, 5-triazine (RDX) by denitrification .
|
-
- HY-W015410S2
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Disodium succinate-d4 is the deuterium labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
|
-
- HY-122288
-
|
Bacterial
|
Infection
|
SC 28538 is a compound with antimicrobial activity. SC 28538 exerts its antimicrobial effect by reducing its nitro moiety in an anaerobic environment to form cytotoxic free radicals that can damage DNA and other key biomolecules of microorganisms .
|
-
- HY-106950A
-
Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium
|
Endogenous Metabolite
|
Cardiovascular Disease
|
Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.
|
-
- HY-122289
-
|
Dihydrofolate reductase (DHFR)
Bacterial
|
Infection
|
Metioprim is a competitive inhibitor of bacterial Dihydrofolate reductase (DHFR). Metioprim has inhibitory activity against anaerobic bacteria. Metioprim shows synergistic activity in combination with DDS (HY-B0688) against E. coli. and various mycobacteria .
|
-
- HY-15781
-
|
Bacterial
|
Infection
|
Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-12687S
-
|
Isotope-Labeled Compounds
Bacterial
HIV
Autophagy
|
Infection
|
Tizoxanide-d4 is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].
|
-
- HY-B1369
-
N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
|
Bacterial
Antibiotic
|
Infection
|
Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-W015410S
-
|
Endogenous Metabolite
|
Metabolic Disease
|
Disodium succinate-13C2 is the 13C labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
|
-
- HY-113945
-
|
Antibiotic
Bacterial
|
Infection
|
Abbeymycin is an antibiotic derived from the actinobacterium Streptomyces sp. AB-999F-52. Abbeymycin is a specifically acting antibiotic with antimicrobial activity, primarily targeting anaerobic bacteria. Abbeymycin is employed in research concerning antibiotic discovery and screening .
|
-
- HY-B0479
-
Thiophenicol; Dextrosulphenidol
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-117166
-
K-F-224
|
Bacterial
|
Infection
|
Naftoxate is an ester compound containing aminomethylsulfate, and its ammonium salt analog can inhibit free thiols to chemically weaken the reactive oxygen species (ROS)-sensitive anaerobic bacterium Trichomonas vaginalis and inhibit common pathogens causing vaginal infections: Candida albicans and Staphylococcus aureus .
|
-
- HY-115249R
-
|
Parasite
Antibiotic
Bacterial
|
Infection
|
Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa .
|
-
- HY-15781A
-
|
Bacterial
|
Infection
|
(R)-Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N +-glucuronidation and sulfation. (R)-Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria .
|
-
- HY-B1369A
-
N-Formimidoyl thienamycin; MK0787
|
Antibiotic
Bacterial
|
Infection
|
Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-B0395C
-
DU6859a hydrate
|
Bacterial
Antibiotic
|
Infection
|
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-117778B
-
|
Enolase
Bacterial
Antibiotic
|
Cancer
|
SF2312 ammonium is the ammonium form of SF2312. SF2312 is a phosphonate antibiotic and enolase inhibitor. SF2312 can be isolated from actinomycete Micromonospora, which is active under anaerobic conditions. SF2312 is selectively toxic to ENO1-deleted glioma cells .
|
-
- HY-B1484R
-
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Moxalactam (sodium salt) (Standard) is the analytical standard of Moxalactam (sodium salt). This product is intended for research and analytical applications. Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases .
|
-
- HY-B1825R
-
|
Antibiotic
Bacterial
|
Infection
Cancer
|
Cefoxitin (Standard) is the analytical standard of Cefoxitin. This product is intended for research and analytical applications. Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
|
-
- HY-B0395
-
DU6859a
|
Bacterial
Antibiotic
|
Infection
|
Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-B0831
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Others
|
Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
|
-
- HY-B0479S
-
Thiophenicol-d3; Dextrosulphenidol-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
|
-
- HY-B1923S
-
Pipracil-d5
|
Antibiotic
Bacterial
|
Infection
|
Piperacillin-d5 is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1].
|
-
- HY-B0395B
-
DU6859a monohydrate
|
Bacterial
Antibiotic
|
Infection
|
Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-B0395A
-
DU6859a hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection .
|
-
- HY-116974
-
ent-Thiophenicol; ent-Dextrosulphenidol
|
Antibiotic
|
Others
|
ent-Thiamphenicol (ent-Dextrosulphenidol) is a enantiomer of Thiamphenicol (HY-B0479). Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-N0420A
-
Wormwood acid tromethamine
|
Endogenous Metabolite
|
Neurological Disease
|
Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries .
|
-
- HY-157326
-
|
Monoamine Oxidase
|
Neurological Disease
|
hMAO-B-IN-6 (compound 17d) is a potent and selective inhibitor of hMAO-B with an IC50 of 67.02 nM. hMAO-B-IN-6 significantly improves Scopolamine (HY-N0296)-induced cognitive impairment in AD mice .
|
-
- HY-B0479R
-
Thiophenicol (Standard); Dextrosulphenidol (Standard)
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Thiamphenicol (Standard) is the analytical standard of Thiamphenicol. This product is intended for research and analytical applications. Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-113829
-
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
Valnemulin is an orally active broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, anaerobic bacteria, Mycoplasma, and Spirochetes. Valnemulin ameliorates enteric diseases, acute polyarthritis and enzootic pneumonia in pigs . Valnemulin exhibits anti-inflammatory efficacy against lipopolysaccharide (HY-D1056)-induced lung injury .
|
-
- HY-B1369R
-
|
Bacterial
Antibiotic
|
Infection
|
Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-B1257
-
Sodium cefmetazole
|
Bacterial
Antibiotic
|
Infection
|
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B1595
-
CS 1170
|
Antibiotic
Bacterial
|
Infection
|
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B1369AR
-
|
Antibiotic
Bacterial
|
Infection
|
Imipenem (Standard) is the analytical standard of Imipenem. This product is intended for research and analytical applications. Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
- HY-B0395CR
-
|
Bacterial
Antibiotic
|
Infection
|
Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections .
|
-
- HY-B0831S
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Metabolic Disease
|
Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
|
-
- HY-B0831R
-
|
Oxidative Phosphorylation
Reactive Oxygen Species
|
Others
|
Buprofezin (Standard) is the analytical standard of Buprofezin. This product is intended for research and analytical applications. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase .
|
-
- HY-B1257R
-
|
Bacterial
Antibiotic
|
Infection
Cancer
|
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-13678
-
SM 7338
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-13678A
-
SM 7338 trihydrate
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-115658
-
|
Bacterial
|
Infection
Metabolic Disease
|
VU0420373 is a potent heme sensor system (HssRS) activator with an EC50 of 10.7 μM and a pEC50 of 4.97. VU0420373 induces heme biosynthesis, and is toxic to fermenting S. aureus .
|
-
- HY-13678S1
-
SM 7338-d6-1
|
Bacterial
Antibiotic
|
Infection
|
Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-13678AR
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-13678R
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (Standard) is the analytical standard of Meropenem. This product is intended for research and analytical applications. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-W740053
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-B0479S1
-
Thiophenicol-d3-1; Dextrosulphenidol-d3-1
|
Isotope-Labeled Compounds
|
Infection
|
Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-A0170
-
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-103399
-
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-B1118S2
-
RP-14539-d4; PM-185184-d4
|
Bacterial
Parasite
Antibiotic
|
Infection
|
Secnidazole-d4 is the deuterium labeled Secnidazole[1]. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis[1][2][3].
|
-
- HY-P2807J
-
|
Lactate Dehydrogenase
|
Metabolic Disease
|
L-Lactate Dehydrogenase (L-LDH), pig muscle is an L-lactate dehydrogenase found in pig muscle, mainly present in anaerobic tissues (skeletal muscle, red blood cells). L-Lactate Dehydrogenase (L-LDH), pig muscle can interact with acidic liposomes at low pH, causing protein to adsorb onto the liposomes and inhibit enzyme activity. The IC50 values for L-Lactate Dehydrogenase (L-LDH), pig muscle are 0.05 μM for cardiolipin and 1.3 μM for phosphatidylserine liposomes .
|
-
- HY-A0170R
-
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Trovafloxacin (Standard) is the analytical standard of Trovafloxacin. This product is intended for research and analytical applications. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 .
|
-
- HY-B0239S2
-
|
JNK
Apoptosis
VEGFR
MMP
Bacterial
Akt
Autophagy
HIF/HIF Prolyl-Hydroxylase
Antibiotic
Beclin1
|
Cancer
|
Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol[1]. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research[2][3][4].
|
-
- HY-16487
-
TMFX; TA-167 free acid; A-62254 free acid
|
Bacterial
Antibiotic
|
Infection
|
Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .
|
-
- HY-113595
-
TMFX hydrochloride; TA-167; A-62254
|
Antibiotic
Bacterial
|
Infection
|
Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections .
|
-
- HY-16487R
-
|
Bacterial
Antibiotic
|
Infection
|
Temafloxacin (Standard) is the analytical standard of Temafloxacin. This product is intended for research and analytical applications. Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .
|
-
- HY-12687R
-
TIZ (Standard)
|
Bacterial
HIV
Autophagy
Parasite
IKK
Influenza Virus
|
Infection
Cancer
|
Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .
|
-
- HY-N0420
-
Wormwood acid
|
Endogenous Metabolite
|
Neurological Disease
|
Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-W015410
-
|
Endogenous Metabolite
|
Inflammation/Immunology
|
Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-N0420R
-
|
Endogenous Metabolite
|
Neurological Disease
|
Succinic acid (Standard) is the analytical standard of Succinic acid. This product is intended for research and analytical applications. Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-W015410R
-
|
Endogenous Metabolite
|
Inflammation/Immunology
|
Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
|
-
- HY-121195
-
PC-904
|
Bacterial
|
Infection
|
Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
|
-
-
-
HY-L083
-
|
2,161 compounds
|
Mutations in oncogenes and tumor suppressor genes can modify multiple signaling pathways and in turn cell metabolism, which facilitates tumorigenesis. The paramount hallmark of tumor metabolism is “aerobic glycolysis” or the Warburg effect, coined by Otto Warburg in 1926, in which cancer cells produce most of energy from glycolysis pathway regardless of whether in aerobic or anaerobic condition. Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside. The increased uptake of glucose is facilitated by the overexpression of several isoforms of membrane glucose transporters (GLUTs). Likewise, the metabolic pathways of glutamine, amino acid and fat metabolism are also altered. Recent trends in anti-cancer drug discovery suggests that targeting the altered metabolic pathways of cancer cells result in energy crisis inside the cancer cells and can selectively inhibit cancer cell proliferation by delaying or suppressing tumor growth.
MCE provides a unique collection of 2,161 compounds which cover various tumor metabolism-related signaling pathways. These compounds can be used for anti-cancer metabolism targets identification, validation as well anti-cancer drug discovery.
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Cat. No. |
Product Name |
Type |
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- HY-157365
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Microbial Culture
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Anaerobic Agar is a special medium for isolating anaerobic bacteria. The composition of 1 litre medium is 58.4 g anaerobic agar .
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- HY-157366
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Microbial Culture
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Sulfite Agar can be used for the test tube count of anaerobic Reductobacter sulfite. The composition of 1 litre medium is 31 g Sulfite Agar .
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- HY-W740053
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Microbial Culture
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Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N8461
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- HY-B0318
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- HY-117778
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- HY-125919
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- HY-B0239
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- HY-B0239R
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- HY-125496
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- HY-135024
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- HY-B0318R
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- HY-126570
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- HY-B0508
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- HY-N0537
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- HY-135024A
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- HY-W748013
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- HY-106950
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- HY-N0537R
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- HY-106950A
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- HY-B1369
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- HY-113945
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- HY-N0420A
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- HY-113829
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Structural Classification
Natural Products
Animals
Source classification
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Antibiotic
Bacterial
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Valnemulin is an orally active broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria, anaerobic bacteria, Mycoplasma, and Spirochetes. Valnemulin ameliorates enteric diseases, acute polyarthritis and enzootic pneumonia in pigs . Valnemulin exhibits anti-inflammatory efficacy against lipopolysaccharide (HY-D1056)-induced lung injury .
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- HY-B1369R
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- HY-13678
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- HY-13678R
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- HY-N0420
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- HY-W015410
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- HY-N0420R
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- HY-W015410R
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Structural Classification
Ketones, Aldehydes, Acids
Source classification
Endogenous metabolite
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Endogenous Metabolite
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Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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* This product has been "discontinued".
Optimized version of product available:
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0318S1
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Metronidazole-d4 is the deuterium labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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- HY-N0420S
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Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
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- HY-N0420S1
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Succinic-2,2,3,3-d4 acid is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
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- HY-B0318S
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Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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- HY-12687S
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Tizoxanide-d4 is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].
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- HY-B0479S
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Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria)[1][2].
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- HY-B0177S
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Tinidazole-d5 is the deuterium labeled Tinidazole. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa[1].
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- HY-B0508S1
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Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
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- HY-W015410S2
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Disodium succinate-d4 is the deuterium labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
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- HY-W015410S
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Disodium succinate-13C2 is the 13C labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
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- HY-B1923S
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Piperacillin-d5 is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins[1].
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- HY-B0831S
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Buprofezin-d6 is the deuterium labeled Buprofezin. Buprofezin is a broad-spectrum insecticide and chitin synthesis inhibitor that targets developmental stage coleopteran pests.Buprofezin promotes the conversion of energy metabolism from the aerobic tricarboxylic acid (TCA) cycle and oxidative phosphorylation to anaerobic glycolysis. Buprofezin also promotes the production of reactive oxygen species (ROS) by inhibiting cytochrome c oxidase[1][2].
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- HY-13678S1
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Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
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- HY-B0479S1
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Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
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- HY-B1118S2
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Secnidazole-d4 is the deuterium labeled Secnidazole[1]. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis[1][2][3].
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- HY-B0239S2
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Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol[1]. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research[2][3][4].
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Cat. No. |
Product Name |
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Classification |
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- HY-N0537
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Xylose
2 Publications Verification
D-(+)-Xylose; (+)-Xylose; Wood sugar
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Sweetening Agents
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D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.
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- HY-N0420
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Wormwood acid
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Cosolvents
pH Modifiers
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Succinic acid is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid is an important platform chemical. Succinic acid can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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