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Results for "

dinucleotide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Autophagy (1) Bacterial (5) Biochemical Assay Reagents (3) Calcium Channel (4) CD38 (1) DNA Methyltransferase (2) DNA/RNA Synthesis (5) Drug Derivative (1) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (24) Fluorescent Dye (2) Glutamate Dehydrogenase (GLDH) (1) HBV (2) IFNAR (1) Isotope-Labeled Compounds (3) Lactate Dehydrogenase (2) NADPH Oxidase (1) NAMPT (2) NF-κB (2) Nucleoside Antimetabolite/Analog (6) Orthopoxvirus (1) PARP (3) Phosphodiesterase (PDE) (2) Sodium Channel (1) STING (11) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (19) Cardiovascular Disease (8) Infection (7) Inflammation/Immunology (13) Metabolic Disease (25) Neurological Disease (2)
Oligonucleotides:	Nucleoside Phosphoramidites (2) CpG ODNs (2) Cap Analogs (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164690A

*Nicotinamide-guanine dinucleotide* sodium**	Endogenous Metabolite	Metabolic Disease
Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro .

HY-B0445A

NAD sodium Maximum Cited Publications 26 Publications Verification β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine dinucleotide sodium	Endogenous Metabolite	Metabolic Disease
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-131924

Thionicotinamide adenine dinucleotide Thio-NAD	Biochemical Assay Reagents	Others
Thionicotinamide adenine dinucleotide (Thio-NAD) is a dinucleotide substrate .

HY-B1654

Flavin adenine dinucleotide 2 Publications Verification FAD	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-131485

*3-Acetylpyridine adenine dinucleotide, 90%* 3-APAD, 90%; 3-Acetylpyridine NAD, 90%	Lactate Dehydrogenase	Metabolic Disease
3-Acetylpyridine adenine dinucleotide, 90% is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 90% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-134280

8-Br-NHD+ Nicotinamide 8-Br-hypoxanthine dinucleotide	Drug Derivative	Others
8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog .

HY-147342

β-Benzamide adenine dinucleotide	DNA/RNA Synthesis	Others
β-Benzamide adenine dinucleotide is a bioactive metabolite of benzamide nucleoside and a potent inhibitor of inosine 5 '-monophosphate dehydrogenase (IMPDH). β-Benzamide adenine dinucleotide is a potent, competitive inhibitor of human NAD kinase (K_i = 90 µM) .

HY-W250154

*β-Nicotinamide adenine dinucleotide* reduced dipotassium**	Endogenous Metabolite	Metabolic Disease
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-131485A

*3-Acetylpyridine adenine dinucleotide, 95%* 3-APAD, 95%; 3-Acetylpyridine NAD, 95%	Lactate Dehydrogenase	Metabolic Disease
3-Acetylpyridine adenine dinucleotide, 95% (3-APAD, 95%)is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 95% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-W250156

*3-Acetylpyridine adenine dinucleotide* disodium**	Biochemical Assay Reagents	Others
3-Acetylpyridine adenine dinucleotide (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-137592

Nicotinamide 1,N6-ethenoadenine dinucleotide ε-NAD	Fluorescent Dye	Others
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) , a fluorescent analogue of NAD, is able to serve as a substrate for the bacterial toxincatalyzed G-ADP ribosylation of signal-transducing G-proteins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the studies of the ADP ribosylation reaction .

HY-B1654S

*Flavin adenine dinucleotide-13C5 ammonium* FAD-¹³C₅ ammonium	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide- ¹³C5 (FAD- ¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-159849

Cytidylyl-(3′,5′)-uridine	Nucleoside Antimetabolite/Analog	Metabolic Disease
Cytidylyl-(3′,5′)-uridine is a dinucleotide derivative that can be used to study nucleotide metabolism .

HY-B1654A

*Flavin adenine dinucleotide* disodium salt** 2 Publications Verification FAD disodium salt; FAD-Na2	Endogenous Metabolite	Cardiovascular Disease
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-157438

pppApA	Bacterial	Metabolic Disease
pppApA is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA is formed by conjugation between two molecules of ATP .

HY-157438A

pppApA sodium	Bacterial	Metabolic Disease
pppApA sodium is a linear dinucleotide intermediate in the enzymatic production of the bacterial signalling nucleotide c-diAMP. pppApA sodium is formed by conjugation between two molecules of ATP .

HY-130115A

IACS-8803 disodium 1 Publications Verification	STING	Cancer
IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy .

HY-130115B

IACS-8803 diammonium 1 Publications Verification	STING	Cancer
IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy .

HY-B0445B

α-NAD α-Nicotinamide Adenine dinucleotide	Others	Others
α-NAD (α-Nicotinamide Adenine Dinucleotide) serves as a substrate for renalase and functions as an analog of β-NAD, influencing the kinetics of NAD-dependent enzymes, while also playing a crucial role as a cofactor in mitochondrial oxidation-reduction reactions.

HY-159806

UU (3′,5′)-Uridylyluridine	Nucleoside Antimetabolite/Analog	Metabolic Disease
UU ((3′,5′)-Uridylyluridine) is a nucleobase-containing dinucleotide derivative. UU can be used for the study of RNA-related processes .

HY-154924

Thio-NADP S-NADP	Calcium Channel	Cardiovascular Disease
Thio-NADP (S-NADP) is a *nicotinic acid adenine dinucleotide* phosphate (NAADP)** inhibitor. Thio-NADP activates partial Ca ²⁺ release .

HY-157421

Nampt activator-4	NAMPT	Others
Nampt activator-4 is a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT) with an EC₅₀ of 0.058 μM. Nampt activator-4 can enhance the nicotinamide adenine dinucleotide (NAD ⁺) in cells .

HY-137672A

2',3'-Cyclic NADP disodium 2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate	Phosphodiesterase (PDE) Calcium Channel	Neurological Disease
2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.

HY-145010

SN-011 4 Publications Verification	STING	Inflammation/Immunology
SN-011 is a potent and selective mouse and human STING inhibitor, with an IC₅₀ of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease .

HY-163941

GSK_WRN2	DNA/RNA Synthesis	Cancer
GSK_WRN2 is a potent and selective covalent WRN helicase inhibitor that suppresses replication stress caused by DNA (TA)_n dinucleotide repeat expansions. GSK_WRN2 can be used to study microsatellite instability (MSI) cancers .

HY-E70410

NAD Synthetase NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The K_m values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the K_m values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases .

HY-W250163

NAD+ lithium β-DPN lithium; β-NAD lithium; β-Nicotinamide Adenine dinucleotide lithium	Biochemical Assay Reagents	Metabolic Disease
NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .

HY-131041

Ned-K	Calcium Channel	Cardiovascular Disease
Ned-K is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Ned-K is effective at dampening simulated ischaemia and reperfusion (sIR)-induced Ca ²⁺ oscillations in cardiomyocytes .

HY-113432

Nudifloramide 2PY	Endogenous Metabolite PARP	Metabolic Disease
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .

HY-134375

cAIMP Cyclic Adenosine-Inosine Monophosphate	NF-κB IFNAR	Inflammation/Immunology
cAIMP (Cyclic Adenosine-Inosine Monophosphate) is an effective synthetic cyclic dinucleotide. cAIMP activates IRF and NF-κB in the THP1 human monocyte reporter cell line (THP1-Dual). cAIMP induces the secretion of IFNs and pro-inflammatory cytokines in vitro in human blood, with an EC₅₀ of 6.4 μmol/L .

HY-113432R

Nudifloramide (Standard) 2PY (Standard)	Endogenous Metabolite PARP	Metabolic Disease
Nudifloramide (Standard) is the analytical standard of Nudifloramide. This product is intended for research and analytical applications. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .

HY-156205

CdnP-IN-1	Phosphodiesterase (PDE)	Infection
CdnP-IN-1 (compound c82) is a potent and selective non-nucleotide *MTB CDN PDE (CdnP; Mycobacterium tuberculosis* cyclic dinucleotide phosphodiesterase) inhibitor with an IC₅₀** of 18 μM. CdnP-IN-1 does not inhibit the enzymatic activities of three other bacterial CDN PDEs (Yybt, RocR, and GBS-CdnP), a viral CDN PDE (poxin) or mammalian ENPP1 .

HY-B1654R

*Flavin adenine dinucleotide* (Standard)**	Endogenous Metabolite	Cardiovascular Disease

HY-148420

CDN-A	STING	Inflammation/Immunology
CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA or by invading bacterial pathogens, trigger the innate immune system by activating the expression of interferon genes .

HY-B1654AR

*Flavin adenine dinucleotide* (disodium salt) (Standard)**	Endogenous Metabolite	Cardiovascular Disease

HY-E70406

Cholesterol Dehydrogenase, Nocardia sp. CHDH-5	Endogenous Metabolite	Others
Cholesterol Dehydrogenase, Nocardia sp. is an enzyme that uses nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phosphate (NAD(P)) as its cofactor in oxidizing cholesterol to form cholest-4-en-3-one. This enzyme oxidizes the hydroxyl group at the 3 position of the sterol ring to form a ketone.

HY-21545

5'-O-DMT-Bz-rA	Nucleoside Antimetabolite/Analog	Others
5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds synthesis .

HY-130115

IACS-8803	STING	Cancer
IACS-8803 is a highly potent cyclic dinucleotide STING agonist with robust systemic antitumor efficacy .

HY-E70238

2-Azido-NAD Nicotinamide 2-azidoadenine dinucleotide	Glutamate Dehydrogenase (GLDH)	Others
2-Azido-NAD is a NAD ⁺ analog that can be used for visualization of intracellular Poly(ADP ribos)ylation (PARylation) processes .

HY-E70210

GpC Methyltransferase GpC	DNA Methyltransferase	Cancer
GpC Methyltransferase (GpC) is a DNA methylating enzyme. GpC Methyltransferase methylates cytosines in GpC dinucleotides in non-nucleosomal DNA in vitro .

HY-P2809

Malic dehydrogenase, microorganism MDH; EC 1.1.1.37	Endogenous Metabolite	Metabolic Disease
Malate dehydrogenase (EC 1.1.1.37) (MDH) catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes .

HY-139586C

Ulevostinag (isomer 3) MK-1454 (isomer 3)	STING	Cancer
Ulevostinag (isomer 3) (example 246) is a potent cyclic dinucleotide agonist stimulator of interferon genes (STING). Ulevostinag (isomer 3) plays an important role in anti-tumor research .

HY-45491

Dmt-2'-f-dc(ac) amidite 2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite	Nucleoside Antimetabolite/Analog	Others
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .

HY-153838

ODN 5328 ODN 2395 Control	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN 5328 (ODN 2395 Control) can be used as a sequence control for C-class ODN 2395. ODN 5328 shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.

HY-139100B

m7G(5')ppp(5')A diammonium m7GpppA diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium	DNA/RNA Synthesis	Infection
m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-P2804

GAPDH, rabbit muscle GADPH; G3PDH; Glyceraldehyde phosphate dehydrogenase	Endogenous Metabolite	Others
Glyceraldehyde phosphate dehydrogenase (EC 1.2.1.12) is the target of anti-thymocyte and anti-apoptotic agents. Glyceraldehyde phosphate dehydrogenase catalyzes the chain oxidation of reduced nicotinamide adenine dinucleotide by perhydroxyl radicals .

HY-153838A

ODN 5328 sodium ODN 2395 Control sodium	Toll-like Receptor (TLR)	Inflammation/Immunology
ODN 5328 (ODN 2395 Control) sodium can be used as a sequence control for C-class ODN 2395. ODN 5328 sodium shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.

HY-P2987

L-Amino acid oxidase	Endogenous Metabolite	Metabolic Disease
L-Amino acid oxidase is a homodimeric proteins containing flavin adenine dinucleotide. L-Amino acid oxidase can catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia .

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-141663

2',3'-cGAMP-C2-SH	ADC Linker	Cancer
2',3'-cGAMP-C2-SH is a cyclic di-nucleotide (CDN) that can be conjugated to antibodies or antigen-binding fragments targeting specific antigens in the microenvironment of diseased cells or tissue .

Cat. No.	Product Name	Type

HY-B0445A

NAD sodium Maximum Cited Publications 26 Publications Verification β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine dinucleotide sodium	Enzyme Substrates
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-131485

*3-Acetylpyridine adenine dinucleotide, 90%* 3-APAD, 90%; 3-Acetylpyridine NAD, 90%	Gene Sequencing and Synthesis
3-Acetylpyridine adenine dinucleotide, 90% is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 90% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-W250154

β-Nicotinamide adenine dinucleotide reduced dipotassium

Biochemical Assay Reagents

β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-131485A

*3-Acetylpyridine adenine dinucleotide, 95%* 3-APAD, 95%; 3-Acetylpyridine NAD, 95%	Gene Sequencing and Synthesis
3-Acetylpyridine adenine dinucleotide, 95% (3-APAD, 95%)is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 95% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite .

HY-W250156

*3-Acetylpyridine adenine dinucleotide* disodium**	Biochemical Assay Reagents
3-Acetylpyridine adenine dinucleotide (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-154924

Thio-NADP S-NADP	Biochemical Assay Reagents
Thio-NADP (S-NADP) is a *nicotinic acid adenine dinucleotide* phosphate (NAADP)** inhibitor. Thio-NADP activates partial Ca ²⁺ release .

HY-W250163

NAD+ lithium β-DPN lithium; β-NAD lithium; β-Nicotinamide Adenine dinucleotide lithium	Biochemical Assay Reagents
NAD+ lithium (β-DPN lithium) is a lithium salt of nicotinamide adenine dinucleotide. NAD+ is a coenzyme in the REDOX reaction. NAD+ can directly or indirectly affect several key cellular functions, including metabolic pathways, DNA repair, chromatin remodeling, cell aging, and immune cell function .

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA	Gene Sequencing and Synthesis
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1654

Flavin adenine dinucleotide 2 Publications Verification FAD	Cardiovascular Disease Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-B1654A

*Flavin adenine dinucleotide* disodium salt** 2 Publications Verification FAD disodium salt; FAD-Na2	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-113432

Nudifloramide 2PY	Alkaloids Structural Classification Other disease Classification of Application Fields Source classification Disease markers Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite PARP
Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .

HY-113432R

Nudifloramide (Standard) 2PY (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite PARP
Nudifloramide (Standard) is the analytical standard of Nudifloramide. This product is intended for research and analytical applications. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro .

HY-B0445

NAD+ Maximum Cited Publications 26 Publications Verification β-DPN; β-NAD; β-Nicotinamide Adenine dinucleotide	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-B0456

Riboflavin 3 Publications Verification Vitamin B2; E101	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Bacterial
Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .

HY-113273B

Diadenosine pentaphosphate pentaammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Diadenosine pentaphosphate pentaammonium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes .

HY-W250154

*β-Nicotinamide adenine dinucleotide* reduced dipotassium**	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
β-Nicotinamide adenine dinucleotide reduced dipotassium is an orally active reduced coenzyme. β-Nicotinamide adenine dinucleotide reduced dipotassium is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide reduced dipotassium plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-B1654R

*Flavin adenine dinucleotide* (Standard)**	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms other families Source classification Plants Endogenous metabolite	Endogenous Metabolite

HY-B1654AR

*Flavin adenine dinucleotide* (disodium salt) (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite

HY-113273C

Diadenosine pentaphosphate pentalithium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Diadenosine pentaphosphate pentalithium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes .

HY-113273A

Diadenosine pentaphosphate pentasodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Diadenosine pentaphosphate pentasodium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes .

HY-B0456R

Riboflavin (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite Bacterial
Riboflavin (Standard) is the analytical standard of Riboflavin. This product is intended for research and analytical applications. Riboflavin, an orally active and easily absorbed micronutrient, is a precursor of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which serve as coenzymes for numerous enzymatic reactions and perform key metabolic functions by mediating the transfer of electrons in biological oxidation-reduction reaction .

Cat. No.	Product Name	Chemical Structure

HY-B1654S

*Flavin adenine dinucleotide-13C5 ammonium*
Flavin adenine dinucleotide- ¹³C5 (FAD- ¹³C5) ammonium is ¹³C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.

HY-113432S

Nudifloramide-d3
Nudifloramide-d₃ (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].

HY-W654288

NAD+-d4
NAD+-d₄ is the deuterium-labeled NAD+ (HY-B0445). NAD+-d₄ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

HY-B0445S

NAD+-13C5 ammonium
NAD+-13C5 (ammonium) is the ¹³C labled NAD+ (HY-B0445), with an ammonium .

HY-B0445S1

NAD+-13C5
NAD+- ¹³C₅-1 is the ¹³C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Cat. No.	Product Name		Classification

HY-21545

5'-O-DMT-Bz-rA		Nucleoside Phosphoramidites
5'-O-DMT-Bz-rA is an intermediate for cyclic di-nucleotide compounds synthesis .

HY-45491

Dmt-2'-f-dc(ac) amidite 2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite		Nucleoside Phosphoramidites
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides .

HY-139100B

m7G(5')ppp(5')A diammonium m7GpppA diammonium; N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium		Cap Analogs Cap Analogs
m7G(5')ppp(5')A (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-153838

ODN 5328 ODN 2395 Control		CpG ODNs
ODN 5328 (ODN 2395 Control) can be used as a sequence control for C-class ODN 2395. ODN 5328 shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.

HY-153838A

ODN 5328 sodium ODN 2395 Control sodium		CpG ODNs
ODN 5328 (ODN 2395 Control) sodium can be used as a sequence control for C-class ODN 2395. ODN 5328 sodium shares the sequence with ODN 2395 but contain GpC dinucleotides instead of the CpG motifs.

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA		Cap Analogs
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

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