Search Result
Results for "
ethanol
" in MedChemExpress (MCE) Product Catalog:
26
Biochemical Assay Reagents
6
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-W010155
-
-
-
- HY-W014334
-
-
-
- HY-W074486
-
-
-
- HY-W007853
-
|
|
PROTAC Linkers
|
Cancer
|
|
2-(Benzyloxy)ethanol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
-
- HY-W016857
-
|
|
Herbicide
|
Others
|
|
2-(4-Chlorophenoxy)ethanol is used as an intermediate (such as for herbicides) .
|
-
-
- HY-Y1783
-
|
N-Methylethanolamine
|
Biochemical Assay Reagents
|
Others
|
|
2-(Methylamino)ethanol (N-Methylethanolamine) is an alkaloid that can be isolated from lentil seeds. 2-(Methylamino)ethanol is used as an organic building block in chemical synthesis and as a solvent for removing carbon dioxide from gas streams .
|
-
-
- HY-W040313
-
-
-
- HY-138479
-
|
|
PROTAC Linkers
|
Cancer
|
|
Benzyl-PEG2-ethanol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-W010583S
-
-
-
- HY-44408
-
-
-
- HY-156517
-
|
|
ADC Cytotoxin
Topoisomerase
|
Cancer
|
|
7Ethanol-10NH2-11F-Camptothecin is a Camptothecin (HY-16560) analogue that serves as an ADC cytotoxin for the synthesis of antibody-drug conjugates (ADCs). 7Ethanol-10NH2-11F-Camptothecin can inhibit tumor growth and is used in cancer research .
|
-
-
- HY-113924
-
|
|
PROTAC Linkers
|
Cancer
|
|
Tri(t-butoxycarbonylethoxymethyl) ethanol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-156515
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a drug-linker conjugates for ADC. MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) is a MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) with protease cleavable MC-GGFG linker .
|
-
-
- HY-W382009
-
|
|
PROTAC Linkers
|
Cancer
|
|
7-Azaspiro[3.5]nonane-2-ethanol is a PROTAC linker can be used in the synthesis of PROTAC, KTX-951 (HY-148290) .
|
-
![7-Azaspiro[3.5]nonane-2-ethanol](//file.medchemexpress.eu/product_pic/hy-w382009.gif)
-
- HY-W101437R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-(6-Methoxy-2-naphthyl)ethanol (Standard) is the analytical standard of 1-(6-Methoxy-2-naphthyl)ethanol. This product is intended for research and analytical applications. 1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-W017395
-
|
N-Benzylethanolamine
|
Biochemical Assay Reagents
|
Others
|
|
2-(Benzylamino)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-W016876
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-(Naphthalen-1-yl)ethanol is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
-
- HY-W010519
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-N6890
-
|
|
Others
|
Metabolic Disease
|
|
Tarasaponin VI is a natural product isolated from Aralia elata. Tarasaponin VI shows potent inhibitory activity on ethanol absorption .
|
-
-
- HY-W250300
-
|
Ethylene glycol monododecyl ether
|
Biochemical Assay Reagents
|
Others
|
|
2-(Dodecyloxy)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-160094
-
|
|
Ligands for Target Protein for PROTAC
|
Cancer
|
|
BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol (compound 71) is a Ligands for Target Protein for PROTAC that contains a sulfonamide linker to increase the solubility of the linker-conjugate. BCN-sulfonamide-PEG2-sulfonamide-N-bis ethanol can be used to synthesize PROTACs with antitumor activity .
|
-
-
- HY-W101437
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
-
- HY-105960A
-
-
-
- HY-W042417S
-
|
N-Benzyl-N-methylethanolamine-d4
|
Isotope-Labeled Compounds
|
Others
|
|
2-(Benzyl(methyl)amino)ethanol-d4 is the deuterium labeled 2-(Benzyl(methyl)amino)ethanol[1].
|
-
-
- HY-24470B
-
-
-
- HY-W777583
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 is the 13C labeled isotope of 2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 (HY-W777583) .
|
-
![2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6](//file.medchemexpress.eu/product_pic/hy-w777583.gif)
-
- HY-Y0417S
-
|
Poly-Solv DE-d5; Seahosol DG-d5; Shihozoru DG-d5
|
Isotope-Labeled Compounds
|
Others
|
|
2-(2-Ethoxyethoxy)ethanol-d5 is the deuterium labeled 2-(2-Ethoxyethoxy)ethanol[1].
|
-
-
- HY-168870
-
|
|
PROTAC Linkers
|
Others
|
|
OH-PEG3-C2-Succinamic acid-2-(Methylamino)ethanol is a PROTAC Linker that can be used to synthesize PROTAC Tamoxifen-PEG-Clozapine (HY-168869) .
|
-
-
- HY-N1496
-
|
|
Others
|
Others
|
|
15,16-Di-O-acetyldarutoside (compound 5) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
|
-
-
- HY-114452A
-
|
BTRX-246040 tartrate
|
Opioid Receptor
|
Neurological Disease
|
|
LY2940094 (BTRX-246040) tartrate is a potent, brain penetrant, selective and orally available N/OFQ peptide (NOP) receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 tartrate reduces Ethanol self-administration and Ethanol seeking in animal models .
|
-
-
- HY-123856
-
|
|
Phosphatase
NF-κB
c-Met/HGFR
Anaplastic lymphoma kinase (ALK)
|
Cardiovascular Disease
Neurological Disease
|
|
MY10 is a potent and orally active receptor protein tyrosine phosphatase (RPTPβ/ζ) inhibitor. MY10 reduces NF-κB p65 expression. MY10 activates tyrosine phosphorylation of c-Met. MY10 prevents the alcohol-induced downregulation of Ptprz1 and Alk expression. MY10 attenuates binge-like ethanol consumption and ethanol reward. MY10 can be used in the study of neurological and vascular diseases .
|
-
-
- HY-103500
-
-
-
- HY-120967
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
-
-
- HY-105034
-
|
BMY 13859-1 free base
|
5-HT Receptor
|
Neurological Disease
|
|
Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm .
|
-
-
- HY-122666
-
|
|
GlyT
|
Metabolic Disease
|
|
Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse .
|
-
-
- HY-125139
-
|
ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%
|
Biochemical Assay Reagents
|
Cardiovascular Disease
Others
|
|
omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.
|
-
-
- HY-123966
-
|
|
Phosphatase
|
Neurological Disease
|
|
MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction .
|
-
-
- HY-123966A
-
|
|
Phosphatase
|
Neurological Disease
|
|
MY33-3 hydrochloride is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP)β/ζ, with an IC50 of ~0.1 μM. MY33-3 hydrochloride also inhibits PTP-1B (IC50 ~0.7 μM). MY33-3 hydrochloride can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction .
|
-
-
- HY-134564
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
|
-
-
- HY-77490A
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
Neurological Disease
|
|
1,3-Butanediol, an orally active ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol administeration can stimulate the biosynthesis of the ketone body, β-hydroxybutyrate (βHB). 1,3-Butanediol has cerebral protective and hypoglycaemic effect .
|
-
-
- HY-77490AR
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
Neurological Disease
|
|
1,3-Butanediol (Standard) is the analytical standard of 1,3-Butanediol. This product is intended for research and analytical applications. 1,3-Butanediol, an ethanol dimer providing a source of calories for human nutrition. 1,3-Butanediol is converted in the body to β-hydroxybutyrate and has cerebral protective and hypoglycaemic effect .
|
-
-
- HY-114452
-
|
BTRX-246040
|
Opioid Receptor
|
Neurological Disease
|
|
LY2940094 (BTRX-246040) is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 reduces ethanol self-administration in animal models .
|
-
-
- HY-138879B
-
|
(1S,5R)-CP-601927
|
nAChR
|
Neurological Disease
|
|
CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .
|
-
-
- HY-161964
-
-
-
- HY-10895
-
|
SB 334867A
|
Orexin Receptor (OX Receptor)
|
Neurological Disease
Endocrinology
|
|
SB-334867 (SB 334867A) is an excellent,selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively . SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo .
|
-
-
- HY-10895A
-
|
SB334867A free base
|
Orexin Receptor (OX Receptor)
|
Neurological Disease
Endocrinology
|
|
SB-334867 free base (SB334867A free base) is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively . SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo .
|
-
-
- HY-W392209A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Copovidone can be used as an excipient, such as Film formers, adhesives, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
-
- HY-147428
-
|
MM-110; (±)-18-Methoxycoronaridine
|
nAChR
Parasite
|
Infection
Neurological Disease
|
|
Zolunicant (MM-110) is a potent inhibitor against nicotinic α3β4 receptors with an IC50 of 0.90 μM to combat addiction. Zolunicant can decrease the self-administration of several addictive agents including morphine, methamphetamine, nicotine, and ethanol in rat model. Zolunicant can be studied as a potential research for multiple forms of agent abuse . Zolunicant also reveals a potent leishmanicide effect against Leishmania amazonensis .
|
-
-
- HY-103476
-
|
|
GABA Receptor
|
Neurological Disease
|
|
Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
-
- HY-163969
-
-
- HY-N10864
-
|
|
Others
|
Others
|
|
Imbricataflavone A, a imbricataflavone, can be isolated from 70% ethanol extract of C. chinensis .
|
-
- HY-N3882
-
|
|
Others
|
Others
|
|
Eurycarpin A is isoflavonoid analog isolated from the ethanol extract of the Chinese folk medicine Crotalaria ferruginea .
|
-
- HY-N13702
-
|
|
Others
|
Others
|
|
Secoaristolenedioic acid (Compound 1) is a sesquiterpene, which is found in ethanol extract of the roots and rhizomes of Nardostachys chinensis .
|
-
- HY-W016509
-
|
|
Endogenous Metabolite
|
Others
|
|
epi-Inositol is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Ethanol Consumption .
|
-
- HY-N11985
-
|
|
Others
|
Others
|
|
Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers .
|
-
- HY-W099586
-
|
Myristic acid ethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl tetradecanoate, which is an ester formed by the condensation of ethanol and myristic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries.
|
-
- HY-N12359
-
|
|
Others
|
Others
|
|
Mulberrofuran B can be isolated from the Ethanol extract of Morus alba. Mulberrofuran B has antioxidant activity .
|
-
- HY-W130500A
-
-
- HY-U00402
-
-
- HY-N1603
-
|
|
Others
|
Others
|
|
16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
|
-
- HY-137231B
-
|
|
nAChR
|
Neurological Disease
|
|
(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction .
|
-
- HY-137231A
-
|
|
nAChR
|
Neurological Disease
|
|
(S)-UFR2709 is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 acts as an anxiolytic agent and can be used for the study of nicotine addiction .
|
-
- HY-105960
-
-
- HY-123080
-
|
|
Others
|
Others
|
|
Tanshinol B is a bioactive component of Salvia miltiorrhiza, which can be isolated from the 50% ethanol extract of the roots and rhizomes of Seaweed prowazekii .
|
-
- HY-N2749
-
|
|
Others
|
Others
|
|
7-Hydroxy-5,8-dimethoxyflavanone is a compound isolated from the ethanol extract of the whole plants of Sarcandra hainanensis .
|
-
- HY-N6655
-
|
|
Amino Acid Derivatives
|
Inflammation/Immunology
|
|
DL-methionine methylsulfonium chloride is a naturally occurring methionine derivative. DL-methionine methylsulfonium chloride protects gastric mucosal from ethanol-induced damage .
|
-
- HY-N8262
-
|
|
Influenza Virus
|
Infection
|
|
Dehydrocorybulbine chloride is an isoquinoline alkaloid with neuraminidase (NA) inhibitory activity. Dehydrocorybulbine chloride can be isolated from the 95% ethanol extract of the rhizome of Viola odorata .
|
-
- HY-13941
-
|
1-NA-PP 1
|
Src
PKD
|
Cancer
|
|
1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively .
|
-
- HY-N0018
-
-
- HY-W012728
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-N11021
-
|
|
Others
|
Others
|
|
Feruloyl tyramine, an amide compound, can be isolated from ethanol extract of hemp seed. Feruloyl tyramine injected into the lateral ventricle caused hypothermia and dyskinesia in mice .
|
-
- HY-N9483
-
|
7-Oxo-DHEA; 7-Ketodehydroepiandrosterone; 7-Oxodehydroepiandrosterone
|
GABA Receptor
|
Metabolic Disease
|
|
7-Keto-DHEA binds to GABA Receptor, and reduces the ethanol intake in rats. 7-Keto-DHEA exhibits potential in investigation of alcohol dependence disorders .
|
-
- HY-118470
-
|
Butoxamin hydrochloride
|
Adrenergic Receptor
|
Endocrinology
|
|
Butaxamine (Butoxamin) hydrochloride is a specific β2-adrenergic receptor blocker. Butaxamine hydrochloride inhibits the decreases in urine volume in ethanol-anesthetized, water-diuretic rats .
|
-
- HY-P2740B
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
Alcohol dehydrogenase, yeast is an alcohol dehydrogenase expressed in yeast. It can catalyze the conversion between ethanol and acetaldehyde, while also reducing NAD or NADP, and it plays a role in glycolysis and aerobic respiration .
|
-
- HY-N4067
-
|
isoCDCA
|
Drug Metabolite
|
Inflammation/Immunology
Cancer
|
|
Isochenodeoxycholic acid (isoCDCA) is a human fecal bile acid. Isochenodeoxycholic acid has cytoprotective against ethanol-induced cell injuries in HepG2 cells. Isochenodeoxycholic acid is a major metabolite of orally administered ursodeoxycholic acid (UDCA) .
|
-
- HY-158051
-
|
|
PKC
|
Neurological Disease
|
|
CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (Ki=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner .
|
-
- HY-Y1147
-
|
Maleic acid diethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells .
|
-
- HY-N2809
-
|
|
Others
|
Others
|
|
Acantrifoside E (Compound 8) is a nature compound. Acantrifoside E can be isolated from the 90% ethanol extract of Salacia cochinchinensis. Acantrifoside E has none α-glucosidase inhibitory activity .
|
-
- HY-121203A
-
|
|
Serotonin Transporter
|
Neurological Disease
|
|
Citalopram oxalate is a serotonin uptake inhibitor that serves as an antidepressant, effectively reducing ethanol uptake in alcoholics and offering a preferable option for depressed patients experiencing tardive dyskinesia compared to tricyclic antidepressants, which may worsen this condition.
|
-
- HY-N0537R
-
|
|
Endogenous Metabolite
|
Others
|
|
Xylose (Standard) is the analytical standard of Xylose. This product is intended for research and analytical applications. D-(+)-xylose (Xylose) is a natural compound that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of xylose.
|
-
- HY-W141881
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research .
|
-
- HY-107248
-
|
|
Others
|
Inflammation/Immunology
|
|
Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats .
|
-
- HY-N0018R
-
|
|
Mitochondrial Metabolism
Reverse Transcriptase
Aldehyde Dehydrogenase (ALDH)
|
Others
|
|
Daidzin (Standard) is the analytical standard of Daidzin. This product is intended for research and analytical applications. Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .
|
-
- HY-107247
-
|
|
Others
|
Inflammation/Immunology
|
|
Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals . Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions .
|
-
- HY-161254
-
|
|
Apoptosis
MDM-2/p53
|
Inflammation/Immunology
Cancer
|
|
ATPase-IN-3 (compound 6) is a ATPase inhibitor. ATPase-IN-3 has Gastroprotective effect in ethanol-induced gastric ulcers by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins .
|
-
- HY-W115738
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PAR is an azo dye widely used as a colorimetric reagent for metal ions. PAR forms stable chelates with different metal ions. PAR can also complex with heavy metal ions in polar organic solvent like ethanol .
|
-
- HY-N9588
-
|
|
Others
|
Cancer
|
|
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
|
-
- HY-P3555
-
-
- HY-P3555A
-
|
|
Opioid Receptor
|
Others
|
|
D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
|
-
- HY-N4193
-
Glabrol
1 Publications Verification
|
Acyltransferase
|
Cardiovascular Disease
|
|
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity .
|
-
- HY-N1035
-
|
|
Others
|
Others
|
|
Urs-12-ene-3β,16β,22α-triol is a terpenoid compound isolated from the ethanol extract of fresh aerial parts of the Patagonian shrub Nardophyllum bryoides .
|
-
- HY-126241
-
|
|
Aldehyde Dehydrogenase (ALDH)
|
Inflammation/Immunology
|
|
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity . RV01 decreases iNOS expression, with anti-neuroinflammatory activity .
|
-
- HY-123789
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
T-5342126 is a toll-like receptor 4 (TLR4) antagonist. It reduces LPS-induced production of nitric oxide (NO) in RAW 264.7 cells (IC50=27.8 μM), as well as decreases LPS-induced IL-8, TNF-α, and IL-6 production in isolated human whole blood (IC50s=110.5, 315.6, and 318.4 μM, respectively). T-5342126 (82 mg/kg) reduces ethanol intake and the abundance of ionized calcium-binding adapter molecule 1 (Iba1), a marker of microglial activation, in the central nucleus of the amygdala in ethanol-dependent mice.
|
-
- HY-W008865
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PIPES sesquisodium is a pH buffer. PIPES refers to Piperazine N-N’-bis [2 ethanol sulphonic acid, an organic based buffer. PIPES can be used in the preparation of a variety of marine and mammalian tissues for electron microscopic study, with pH range of 6.1-7.5 .
|
-
- HY-116016
-
|
L-DOPA ethyl ester; Levodopa ethyl ester
|
Dopamine Receptor
Drug Metabolite
|
Neurological Disease
|
|
Etilevodopa (L-Dopa ethyl ester), an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
|
-
- HY-116016A
-
|
L-DOPA ethyl ester hydrochloride; Levodopa ethyl ester hydrochloride
|
Dopamine Receptor
Drug Metabolite
|
Neurological Disease
|
|
Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
|
-
- HY-N3344
-
|
|
Fungal
|
Others
|
|
Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation .
|
-
- HY-N2325
-
|
|
Endogenous Metabolite
|
Others
|
|
D-(+)-Cellobiose is a water-soluble disaccharide and an important intermediate product in the degradation process of cellulose and hemicellulose. D-(+)-cellobiose is used as a carbon source by microorganisms in fermentation processes, where it is converted into ethanol or other metabolic products. D-(+)-Cellobiose has significant application value in biofuel production, such as bioethanol .
|
-
- HY-N8989
-
|
|
Lipase
|
Metabolic Disease
|
|
(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC50 value of 23.9 µg/mL. Antiobesity Effect .
|
-
- HY-N11137
-
|
|
Bacterial
|
Infection
|
|
3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria .
|
-
- HY-W013809
-
|
Stearic acid ethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl stearate is an ester compound produced by the reaction of ethanol and stearic acid. It is commonly used as a flavoring agent in various foods such as baked goods, beverages and desserts. Ethyl stearate is also used as a fragrance ingredient in the manufacture of perfume, cologne and personal care products. Additionally, it has applications in industrial settings such as the production of lubricants and plasticizers.
|
-
- HY-125773
-
|
Beta-cyano-l-alanine
|
Endogenous Metabolite
|
Neurological Disease
|
|
β-cyano-L-Alanine (Beta-cyano-l-alanine), a nitrile of widespread occurrence in higher plants, is enzymatically produced by cyanoalanine synthase from cyanide and cysteine as substrates . β-cyano-L-Alanine abolishes the protective effect of ethanol on cerebral ischemia/reperfusion (I/R) injury .
|
-
- HY-N7905
-
|
|
Others
|
Inflammation/Immunology
|
|
Myricetin 3'-glucoside is a glycoside derivative of quercetin. Myricetin 3'-glucoside significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells. Myricetin 3'-glucoside has a certain protective effect on alcohol-induced liver injury .
|
-
- HY-N2086S
-
|
Ethyl hexadecanoate-d31
|
Isotope-Labeled Compounds
|
Others
|
|
Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
|
-
- HY-N2086R
-
|
|
Others
|
Others
|
|
Ethyl palmitate (Standard) is the analytical standard of Ethyl palmitate. This product is intended for research and analytical applications. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
|
-
- HY-125540
-
|
|
Influenza Virus
|
Infection
Inflammation/Immunology
|
|
Saussureamine C shows gastroprotective effect on acidified ethanol-induced gastric mucosal lesions in rats. Saussureamine C inhibits H274Y and N294S mutants and can be used for research of influenza virus infection. Saussureamine C can be isolated from the dried roots of Saussurea lappa Clarke .
|
-
- HY-106083
-
|
RHC 3988
|
Others
|
Inflammation/Immunology
|
|
Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers .
|
-
- HY-B0203B
-
|
(Rac)-R 065824
|
Adrenergic Receptor
NADPH Oxidase
|
Cardiovascular Disease
|
|
(Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity .
|
-
- HY-W127583
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl trans-4-decenoateIt is an organic compound belonging to esters. It consists of ethanol and trans-4-Decenoic acid reacts to form. Ethyl trans-4-decenoateIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as a flavoring agent in food.
|
-
- HY-W015305
-
|
Octanoic acid ethyl ester
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl octanoate is a class of esters consisting of the medium-chain fatty acid octanoic acid esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl octanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-N0115
-
|
Gastrodine
|
Apoptosis
Ferroptosis
|
Cardiovascular Disease
Neurological Disease
Inflammation/Immunology
|
|
Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
|
-
- HY-W014207
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl undecanoate is a class of esters consisting of long-chain straight-chain fatty acids, undecanoic acid, esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl undecanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W013809R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl stearate (Standard) is the analytical standard of Ethyl stearate. This product is intended for research and analytical applications. Ethyl stearate is an ester compound produced by the reaction of ethanol and stearic acid. It is commonly used as a flavoring agent in various foods such as baked goods, beverages and desserts. Ethyl stearate is also used as a fragrance ingredient in the manufacture of perfume, cologne and personal care products. Additionally, it has applications in industrial settings such as the production of lubricants and plasticizers.
|
-
- HY-W007511
-
|
Isohexanol; Isohexyl alcohol
|
Biochemical Assay Reagents
|
Neurological Disease
|
|
4-Methyl-1-pentanol is a volatile aroma component of red wine, which is often used in the production and blending of wine. 4-Methyl-1-pentanol can also be used as an alcohol antagonist to antagonize the effects of ethanol and 1-butanol on cell-cell adhesion, and is used in the study of fetal alcohol syndrome .
|
-
- HY-W013203
-
|
Icosanoic Acid Ethyl Ester
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl icosanoate is an ester, which is formed by the esterification of long-chain straight-chain fatty acids, eicosanoic acid and ethanol. The compound has a fruity, waxy smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl icosanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W076441
-
|
Ethyl (S)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.
|
-
- HY-W015667
-
|
Ethyl 2-methylvalerate
|
Biochemical Assay Reagents
|
Others
|
|
Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-N7103
-
|
|
Endogenous Metabolite
|
Others
|
|
Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .
|
-
- HY-170586
-
-
- HY-N2025
-
|
|
PPAR
Glycosidase
|
Metabolic Disease
|
|
Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity . Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence .
|
-
- HY-107380A
-
|
A-42872 TFA
|
TSH Receptor
|
Endocrinology
|
|
PGlu-3-methyl-His-Pro-NH2 TFA (A-42872 TFA), the modified thyrotropin-releasing hormone (TRH) peptide, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. The in vitro permeability of PGlu-3-methyl-His-Pro-NH2 TFA through rat skin is increased in the presence of enhancers Ethanol and Cineole .
|
-
- HY-N0537
-
Xylose
3 Publications Verification
D-(+)-Xylose; (+)-Xylose; Wood sugar
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .
|
-
- HY-N13218
-
|
|
Others
|
Cardiovascular Disease
|
|
Pueraria Extract is a kudzu extract, and its components include: Isoflavones. Pueraria Extract (ethanol extract) can significantly improve cardiac damage in rats with acute myocardial infarction. Pueraria Extract improves bile acid levels by increasing the expression of CYP7A1 and restoring the diversity of intestinal microbiota. Pueraria Extract can also inhibit the FXR-FGF15 signaling pathway and increase the expression of OST-α to increase bile acid reabsorption and fecal excretion. .
|
-
- HY-N7103R
-
|
|
Endogenous Metabolite
|
Others
|
|
Ethyl oleate (Standard) is the analytical standard of Ethyl oleate. This product is intended for research and analytical applications. Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .
|
-
- HY-N9182
-
|
Physalien
|
Adiponectin Receptor
P2X Receptor
Autophagy
|
Inflammation/Immunology
|
|
Zeaxanthin dipalmitate (Physalien) is a wolfberry-derived carotenoid, has anti-inflammatory and anti-oxidative stress effects. Zeaxanthin dipalmitate directly interact with p2X7 receptor (Kd=81.2 nM) and adiponectin receptor 1 (AdipoR1; Kd=533 nM) in a positive dose-dependent manner. Zeaxanthin dipalmitate restores mitochondrial autophagy functions suppressed by ethanol intoxication. Zeaxanthin dipalmitate can be used in the research of alcoholic fatty liver disease (AFLD) and retinitis pigmentosa (RP) .
|
-
- HY-B1618
-
Corticosterone
Maximum Cited Publications
38 Publications Verification
17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
|
Glucocorticoid Receptor
Endogenous Metabolite
iGluR
|
Neurological Disease
Inflammation/Immunology
Endocrinology
|
|
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
|
-
- HY-W010507
-
|
Methyl (R)-(-)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
Others
|
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-B0203BS2
-
|
(Rac)-R 065824-d2,15N
|
NADPH Oxidase
Adrenergic Receptor
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
|
(Rac)-Nebivolol-d2, 15N is 15N and deuterated labeled (Rac)-Nebivolol (HY-B0203B). (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity .
|
-
- HY-N1445
-
|
Isoquercetin; Quercetin 3-glucoside
|
NF-κB
NO Synthase
|
Inflammation/Immunology
Cancer
|
|
Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
|
-
- HY-151229
-
|
DETC-Me; DDTC-Me; Diethyldithiocarbamic acid methyl ester
|
Aldehyde Dehydrogenase (ALDH)
|
Metabolic Disease
|
|
S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) is the active metabolite of the aldehyde dehydrogenase inhibitor disulfiram (HY-B0240). It is produced by the methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes. S-Methyl-N,N-diethylthiolcarbamate (DETC-Me; DDTC-Me) inhibits rat liver low Km aldehyde dehydrogenase (ALDH) (ID50=15.5 mg/kg). When administered at a dose of 20.6 mg/kg, it decreases mean arterial pressure (MAP) and increases heart rate in rats during ethanol stimulation.
|
-
- HY-124619
-
|
|
FKBP
HIV
|
Infection
Neurological Disease
|
|
GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models . GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with functional recovery in rodent models . GPI-1046 improves HIV-associated injury of peripheral nerves .
|
-
- HY-N2025R
-
|
|
PPAR
Glycosidase
|
Metabolic Disease
|
|
Oroxin A (Standard) is the analytical standard of Oroxin A. This product is intended for research and analytical applications. Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity . Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence .
|
-
- HY-N11009
-
|
|
EBV
|
Infection
|
|
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
|
-
- HY-N1445R
-
|
Isoquercetin (Standard); Quercetin 3-glucoside (Standard)
|
NF-κB
NO Synthase
|
Inflammation/Immunology
Cancer
|
|
Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
|
-
- HY-W093282
-
|
Soybean oil epoxide
|
Biochemical Assay Reagents
|
Others
|
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
-
- HY-137566
-
|
|
Mitochondrial Metabolism
|
Cancer
|
|
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-134564
-
|
|
Dyes
|
|
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W014334
-
|
|
Biochemical Assay Reagents
|
|
Carbazole-9-ethanol is a biological material or organic compound that can be used in life science research .
|
-
- HY-W074486
-
|
|
Carbohydrates
|
|
1-(4-Chlorophenyl)ethanol is a biochemical assay reagent.
|
-
- HY-W017395
-
|
N-Benzylethanolamine
|
Biochemical Assay Reagents
|
|
2-(Benzylamino)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W016876
-
|
|
Biochemical Assay Reagents
|
|
2-(Naphthalen-1-yl)ethanol is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-120967
-
|
|
Cell Assay Reagents
|
|
(2S)-OMPT (triethylamine), in ethanol:chloroform (1:1), 98%, is commonly used as a ligand in asymmetric catalysis, especially in the enantioselective synthesis of bioactive molecules such as amino acids and drugs. (2S)-OMPT triethylamine has unique chemical properties that allow it to selectively bind certain metal complexes and activate them in a way that favors the formation of specific enantiomers.
|
-
- HY-125139
-
|
ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%
|
Drug Delivery
|
|
omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.
|
-
- HY-W101437R
-
|
|
Biochemical Assay Reagents
|
|
1-(6-Methoxy-2-naphthyl)ethanol (Standard) is the analytical standard of 1-(6-Methoxy-2-naphthyl)ethanol. This product is intended for research and analytical applications. 1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W010519
-
|
|
Biochemical Assay Reagents
|
|
2-(Pyrrolidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W250300
-
|
Ethylene glycol monododecyl ether
|
Biochemical Assay Reagents
|
|
2-(Dodecyloxy)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W101437
-
|
|
Biochemical Assay Reagents
|
|
1-(6-Methoxynaphthalen-2-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-161964
-
|
|
Surfactants
|
|
trans-2-Decen-1-ol is a biochemical assay reagent.
|
-
- HY-163969
-
-
- HY-W130500A
-
|
2-(Hexyloxy)ethanol, 99%
|
Co-solvents
|
|
Ethylene glycol monohexyl ether, 99% is a multifunctional solvent.
|
-
- HY-W012728
-
|
|
Biochemical Assay Reagents
|
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-Y1147
-
|
Maleic acid diethyl ester
|
Biochemical Assay Reagents
|
|
Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells .
|
-
- HY-W008865
-
|
|
Buffer Reagents
|
|
PIPES sesquisodium is a pH buffer. PIPES refers to Piperazine N-N’-bis [2 ethanol sulphonic acid, an organic based buffer. PIPES can be used in the preparation of a variety of marine and mammalian tissues for electron microscopic study, with pH range of 6.1-7.5 .
|
-
- HY-W013809
-
|
Stearic acid ethyl ester
|
Drug Delivery
|
|
Ethyl stearate is an ester compound produced by the reaction of ethanol and stearic acid. It is commonly used as a flavoring agent in various foods such as baked goods, beverages and desserts. Ethyl stearate is also used as a fragrance ingredient in the manufacture of perfume, cologne and personal care products. Additionally, it has applications in industrial settings such as the production of lubricants and plasticizers.
|
-
- HY-W127583
-
|
|
Drug Delivery
|
|
Ethyl trans-4-decenoateIt is an organic compound belonging to esters. It consists of ethanol and trans-4-Decenoic acid reacts to form. Ethyl trans-4-decenoateIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as a flavoring agent in food.
|
-
- HY-W015305
-
|
Octanoic acid ethyl ester
|
Drug Delivery
|
|
Ethyl octanoate is a class of esters consisting of the medium-chain fatty acid octanoic acid esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl octanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W014207
-
|
|
Drug Delivery
|
|
Ethyl undecanoate is a class of esters consisting of long-chain straight-chain fatty acids, undecanoic acid, esterified with ethanol. The compound has a fruity smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl undecanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W013809R
-
|
|
Drug Delivery
|
|
Ethyl stearate (Standard) is the analytical standard of Ethyl stearate. This product is intended for research and analytical applications. Ethyl stearate is an ester compound produced by the reaction of ethanol and stearic acid. It is commonly used as a flavoring agent in various foods such as baked goods, beverages and desserts. Ethyl stearate is also used as a fragrance ingredient in the manufacture of perfume, cologne and personal care products. Additionally, it has applications in industrial settings such as the production of lubricants and plasticizers.
|
-
- HY-W013203
-
|
Icosanoic Acid Ethyl Ester
|
Drug Delivery
|
|
Ethyl icosanoate is an ester, which is formed by the esterification of long-chain straight-chain fatty acids, eicosanoic acid and ethanol. The compound has a fruity, waxy smell and is commonly used as a flavoring in foods such as baked goods, candy and beverages. It is also used as a fragrance ingredient in personal care products and as a lubricant or plasticizer in various industrial applications. In addition, Ethyl icosanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W076441
-
|
Ethyl (S)-3-hydroxybutyrate
|
Biochemical Assay Reagents
|
|
Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.
|
-
- HY-W015667
-
|
Ethyl 2-methylvalerate
|
Biochemical Assay Reagents
|
|
Ethyl 2-methylpentanoate is a class of esters consisting of branched-chain isovaleric acid esterified with ethanol. The compound has a fruity, pungent smell and is commonly used as a flavoring in foods such as baked goods, dairy products and beverages. It can also be used as a fragrance ingredient in personal care products, and as a solvent or plasticizer in various industrial applications. In addition, Ethyl 2-methylpentanoate can be used as a starting material for the synthesis of other organic compounds.
|
-
- HY-W010507
-
|
Methyl (R)-(-)-3-hydroxybutyrate
|
Drug Delivery
|
|
(R)-Methyl 3-hydroxybutanoate, (R)-Methyl 3-hydroxybutanoate is an enantiomer, from the perspective of the methyl (-CH3) group, the hydroxyl (-OH) group on the third carbon atom The group faces to the right, a colorless transparent liquid, soluble in organic solvents such as ethanol and ether, insoluble in water, (R)-Methyl 3-hydroxybutanoate is usually used to synthesize various organic compounds (including drugs, agricultural chemicals and flavoring agents) It can also be used as a chiral auxiliary in asymmetric synthetic reactions involving the formation of chemical bonds in a stereoselective manner.
|
-
- HY-W093282
-
|
Soybean oil epoxide
|
Co-solvents
|
|
Epoxidized soya bean oil (ESBO) is a vegetable oil-derived organic compound used as a plasticizer and stabilizer in various applications. It is produced by epoxidation of soybean oil, which introduces epoxy groups into the fatty acid chains of the oil. ESBO is a viscous, pale yellow liquid that is soluble in many organic solvents, such as chloroform and ethanol, but insoluble in water. It is commonly used as a plasticizer in polyvinyl chloride (PVC) products, including toys, food packaging materials and medical devices. In addition to its plasticizing properties, ESBO acts as an antioxidant and UV stabilizer, helping to prevent degradation and discoloration of PVC products over time. ESBOs have been investigated for their potential use in biodegradable plastics and as bio-based alternatives to traditional petroleum-derived plasticizers.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1555
-
|
Adrenocorticotropic Hormone (1-13)
|
Peptides
|
Inflammation/Immunology
|
|
ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.
|
-
- HY-W141881
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-lauroylsarcosine is an anionic surfactant, and can be used as a permeation enhancer. The mixture of N-lauroylsarcosine in 25-50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research .
|
-
- HY-107380A
-
|
A-42872 TFA
|
TSH Receptor
|
Endocrinology
|
|
PGlu-3-methyl-His-Pro-NH2 TFA (A-42872 TFA), the modified thyrotropin-releasing hormone (TRH) peptide, enhances binding to pituitary TRH receptors and increases stimulation of thyroid-stimulating hormone (TSH) release from the pituitary. The in vitro permeability of PGlu-3-methyl-His-Pro-NH2 TFA through rat skin is increased in the presence of enhancers Ethanol and Cineole .
|
-
- HY-P3555
-
-
- HY-P3555A
-
|
|
Opioid Receptor
|
Others
|
|
D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, is a potent opiate δ-receptor agonist .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W010155
-
-
-
- HY-Y1783
-
-
-
- HY-N6890
-
-
-
- HY-77490A
-
-
-
- HY-W016509
-
-
-
- HY-W040313
-
-
-
- HY-77490AR
-
-
-
- HY-N10864
-
-
-
- HY-N3882
-
-
-
- HY-N13702
-
-
-
- HY-N11985
-
-
-
- HY-N12359
-
-
-
- HY-123080
-
-
-
- HY-N2749
-
-
-
- HY-N6655
-
-
-
- HY-N8262
-
-
-
- HY-N0018
-
-
-
- HY-N11021
-
-
-
- HY-N9483
-
-
-
- HY-N4067
-
|
isoCDCA
|
Microorganisms
Source classification
|
Drug Metabolite
|
|
Isochenodeoxycholic acid (isoCDCA) is a human fecal bile acid. Isochenodeoxycholic acid has cytoprotective against ethanol-induced cell injuries in HepG2 cells. Isochenodeoxycholic acid is a major metabolite of orally administered ursodeoxycholic acid (UDCA) .
|
-
-
- HY-N2809
-
-
-
- HY-N0537R
-
-
-
- HY-107248
-
-
-
- HY-N0018R
-
-
-
- HY-107247
-
-
-
- HY-N9588
-
|
|
Flavonoids
Sesamum indicum Linn.
Pedaliaceae
Plants
Isoflavones
|
Others
|
|
Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP) .
|
-
-
- HY-N4193
-
-
-
- HY-N3344
-
-
-
- HY-N2325
-
-
-
- HY-N8989
-
-
-
- HY-N11137
-
-
-
- HY-125773
-
-
-
- HY-N7905
-
-
-
- HY-N2086R
-
-
-
- HY-125540
-
-
-
- HY-N0115
-
-
-
- HY-W007511
-
-
-
- HY-N2025
-
-
-
- HY-N0537
-
-
-
- HY-N7103R
-
-
-
- HY-N9182
-
-
-
- HY-B1618
-
-
-
- HY-N1445
-
-
-
- HY-N2025R
-
|
|
Structural Classification
Flavonoids
Flavones
Source classification
Bignoniaceae
Plants
Oroxylum indicum (Linn.) Bentham ex Kurz
|
PPAR
Glycosidase
|
|
Oroxin A (Standard) is the analytical standard of Oroxin A. This product is intended for research and analytical applications. Oroxin A is the major component of an ethanol-water Oroxylum indicum (L.) Kurz (Bignoniaceae) seed extract (OISE). Oroxin A acts as a partial PPARγ agonist that can activate PPARγ transcriptional activation. Oroxin A activates PPARγ by docking into the PPARγ protein ligand-binding domain. Oroxin A also exhibits an inhibitory activity against α-glucosidase and an antioxidant capacity . Oroxin A exerts anti-breast cancer effects by inducing ER stress-mediated senescence .
|
-
-
- HY-N11009
-
-
-
- HY-N1445R
-
|
Isoquercetin (Standard); Quercetin 3-glucoside (Standard)
|
Apocynaceae
Flavonols
Structural Classification
Flavonoids
Source classification
Phenols
Polyphenols
Plants
Apocynum venetum Linn.
|
NF-κB
NO Synthase
|
|
Isoquercetin (Standard) is the analytical standard of Isoquercetin. This product is intended for research and analytical applications. Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
|
-
-
- HY-137566
-
|
|
Triterpenes
Structural Classification
Animals
Terpenoids
Source classification
|
Mitochondrial Metabolism
|
|
Cucumarioside H is a novel triterpene glycoside isolated from the Far Eastern sea cucumber Eupentacta fraudatrix, including H2, H3 and H4. These glycosides have a branched pentasyl structure with a rare 3-O-methyl-D-xylose as the terminal monosaccharide. H2 contains 23,24,25,26,27-pentanolone sterols and has an 18(16)-lactone, which is not common in sea cucumbers. The glycoside portion of H3 contains an extremely rare ethoxyl radical at the 25 position, which may be an artifact formed during the long ethanol extraction process. Studies have shown that H1-3 are cytotoxic to mouse spleen lymphocytes, hemolytic to mouse erythrocytes, and cytotoxic to Ehrlich carcinoma cells. The presence of a 25-hydroxyl group in the glycoside portion significantly reduces these activities.
|
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N2086S
-
|
|
|
Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent[1].
|
-
-
- HY-W010583S
-
|
|
|
2-(2-Aminoethylamino)ethanol-d4 is the deuterium labeled 2-((2-Aminoethyl)amino)ethanol[1].
|
-
-
- HY-W042417S
-
|
|
|
2-(Benzyl(methyl)amino)ethanol-d4 is the deuterium labeled 2-(Benzyl(methyl)amino)ethanol[1].
|
-
-
- HY-W777583
-
|
|
|
2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 is the 13C labeled isotope of 2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 (HY-W777583) .
|
-
-
- HY-Y0417S
-
|
|
|
2-(2-Ethoxyethoxy)ethanol-d5 is the deuterium labeled 2-(2-Ethoxyethoxy)ethanol[1].
|
-
-
- HY-B0203BS2
-
|
|
|
(Rac)-Nebivolol-d2, 15N is 15N and deuterated labeled (Rac)-Nebivolol (HY-B0203B). (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-103476
-
|
|
|
Azide
|
|
Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W392209A
-
|
|
|
Binders
|
|
Copovidone can be used as an excipient, such as Film formers, adhesives, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
|
-
- HY-N7103
-
|
|
|
Solvents
|
|
Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .
|
-
- HY-N0537
-
Xylose
3 Publications Verification
D-(+)-Xylose; (+)-Xylose; Wood sugar
|
|
Sweetening Agents
|
|
Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation .
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
![7-Azaspiro[3.5]nonane-2-ethanol](http://file.medchemexpress.eu/product_pic/hy-w382009.gif)
![2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6](http://file.medchemexpress.eu/product_pic/hy-w777583.gif)
