Search Result

Results for "

growth inhibitory

" in MedChemExpress (MCE) Product Catalog:

By Targets:	EGFR (2) TGF-beta/Smad (4) TGF-β Receptor (3) VEGFR (2) 5 alpha Reductase (1) Akt (2) Aminoacyl-tRNA Synthetase (2) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (2) Angiotensin Receptor (2) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (10) Apoptosis (19) Aurora Kinase (1) Autophagy (3) Bacterial (18) Bcr-Abl (1) BRK (1) Btk (1) c-Met/HGFR (1) Caspase (2) CCR (3) CDK (2) Cholinesterase (ChE) (1) COX (1) Cytochrome P450 (4) DNA/RNA Synthesis (4) Drug-Linker Conjugates for ADC (2) E1/E2/E3 Enzyme (1) Endogenous Metabolite (10) Epigenetic Reader Domain (1) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) FAK (1) Farnesyl Transferase (1) FLT3 (1) Fungal (15) G Protein-coupled Receptor Kinase (GRK) (1) HDAC (2) Histone Methyltransferase (1) Influenza Virus (1) Interleukin Related (2) Isotope-Labeled Compounds (1) Kinesin (1) Lipoxygenase (2) METTL3 (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (1) Monoamine Oxidase (2) mTOR (2) NAMPT (1) Notch (1) Opioid Receptor (1) Organoid (2) Parasite (5) Phosphatase (1) PI3K (3) PKD (1) Potassium Channel (1) Prostaglandin Receptor (1) PROTACs (1) Proteasome (1) RAR/RXR (1) Ras (2) RET (1) ROS Kinase (2) Src (1) STAT (2) STING (1) Thymidylate Synthase (2) TNF Receptor (3) TOPK (1) Topoisomerase (1) Tyrosinase (3) Wee1 (1) Wnt (1) α-synuclein (1) β-catenin (1)
By Research Areas:	Cancer (85) Cardiovascular Disease (5) Endocrinology (4) Infection (43) Inflammation/Immunology (15) Metabolic Disease (5) Neurological Disease (6)

By Targets:

EGFR (2)

TGF-beta/Smad (4)

TGF-β Receptor (3)

VEGFR (2)

5 alpha Reductase (1)

Akt (2)

Aminoacyl-tRNA Synthetase (2)

Anaplastic lymphoma kinase (ALK) (1)

Androgen Receptor (2)

Angiotensin Receptor (2)

Angiotensin-converting Enzyme (ACE) (2)

Antibiotic (10)

Apoptosis (19)

Aurora Kinase (1)

Autophagy (3)

Bacterial (18)

Bcr-Abl (1)

BRK (1)

Btk (1)

c-Met/HGFR (1)

Caspase (2)

CCR (3)

CDK (2)

Cholinesterase (ChE) (1)

COX (1)

Cytochrome P450 (4)

DNA/RNA Synthesis (4)

Drug-Linker Conjugates for ADC (2)

E1/E2/E3 Enzyme (1)

Endogenous Metabolite (10)

Epigenetic Reader Domain (1)

Estrogen Receptor/ERR (1)

Eukaryotic Initiation Factor (eIF) (1)

FAK (1)

Farnesyl Transferase (1)

FLT3 (1)

Fungal (15)

G Protein-coupled Receptor Kinase (GRK) (1)

HDAC (2)

Histone Methyltransferase (1)

Influenza Virus (1)

Interleukin Related (2)

Isotope-Labeled Compounds (1)

Kinesin (1)

Lipoxygenase (2)

METTL3 (1)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (1)

MMP (1)

Monoamine Oxidase (2)

mTOR (2)

NAMPT (1)

Notch (1)

Opioid Receptor (1)

Organoid (2)

Parasite (5)

Phosphatase (1)

PI3K (3)

PKD (1)

Potassium Channel (1)

Prostaglandin Receptor (1)

PROTACs (1)

Proteasome (1)

RAR/RXR (1)

Ras (2)

RET (1)

ROS Kinase (2)

Src (1)

STAT (2)

STING (1)

Thymidylate Synthase (2)

TNF Receptor (3)

TOPK (1)

Topoisomerase (1)

Tyrosinase (3)

Wee1 (1)

Wnt (1)

α-synuclein (1)

β-catenin (1)

By Research Areas:

Cancer (85)

Cardiovascular Disease (5)

Endocrinology (4)

Infection (43)

Inflammation/Immunology (15)

Metabolic Disease (5)

Neurological Disease (6)

134

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Macrophage migration inhibitory factor (MIF) FGFR GHR VEGFR TGF-beta/Smad PDGFR TGF-β Receptor GHSR EGFR IGF-1R Nuclear Hormone Receptor 4A/NR4A

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101404

DL-Homocysteine thiolactone hydrochloride	Endogenous Metabolite	Others
DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-122308

Militarine	Others	Metabolic Disease
Militarine, a glycosidic compound isolated from Bletilla striata, exhibits plant growth-inhibitory activity .

HY-W008151

Diphenyl Phosphate	Mitochondrial Metabolism	Metabolic Disease
Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases .

HY-101982A

(Rac)-Lys-SMCC-DM1 (Rac)-Lys-Nε-MCC-DM1	Drug-Linker Conjugates for ADC	Cancer
(Rac)-Lys-SMCC-DM1 ((Rac)-Lys-Nε-MCC-DM1) is the racemate of Lys-SMCC-DM1 (HY-101982). Lys-SMCC-DM1 is a linker-payload component that has the potential to inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1 .

HY-W017401

Benzisothiazolone BIT	Others	Infection Cancer
Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .

HY-W017401R

Benzisothiazolone (Standard)	Others	Infection Cancer
Benzisothiazolone (Standard) is the analytical standard of Benzisothiazolone. This product is intended for research and analytical applications. Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .

HY-129580

Nannochelin B	Bacterial Fungal	Infection
Nannochelin B is a novel citrate-hydroxamate siderophore with a growth-inhibitory activity against some bacteria and fungi .

HY-P5107

Low molecular weight protamine LMWP	VEGFR	Cancer
Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research .

HY-N3231

Murraol CM-c2	Lipoxygenase COX	Cancer
Murraol (CM-c2), a coumarin, can be isolated from the leaves of Madagascar pine cork (Apiaceae). Murraol has cyclooxygenase (COX) and lipoxygenase inhibitory properties and has an inhibitory effect on the growth of cancer cells .

HY-N10278

Pycnophorin	Others	Others
Pycnophorin significantly inhibits the growth of Bacillus subtilis and Staphyloccocus aureus with equal minimum inhibitory concentration (MIC) values of 25 μM.

HY-B0984A

Fendiline	STING	Infection Cancer
Fendiline is a STING agonist and has tumor growth inhibitory activity. Fendiline can be used for research on cancer and viral infections .

HY-N12262

(+)-Epieudesmin	Bacterial	Infection Cancer
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of Gram-negative pathogen .

HY-123135

Scirpusin B	Others	Infection Cancer
Scirpusin B (compound 5) is a dimeric antioxidant isolated from Scirpus maritimus L.. Scirpusin B exhibits antitumor, antifungal, insecticidal, and plant growth inhibitory activities.

HY-B1918

(+)-Bornyl acetate	Others	Others
(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings .

HY-163630

Antibacterial agent 217	Bacterial	Infection
Antibacterial agent 217 (Compound 24) is a non-cytotoxic, non-hemolytic, moderately active antibacterial agent that inhibits the growth of Staphylococcus aureus strains with a minimum inhibitory concentration (MIC) of 32 μg/mL. Antibacterial agent 217 also moderately inhibits the growth of Staphylococcus epidermidis .

HY-19356A

Didesmethylrocaglamide	Eukaryotic Initiation Factor (eIF) Apoptosis	Cancer
Didesmethylrocaglamide, a derivative of Rocaglamide, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. Didesmethylrocaglamide has potent growth-inhibitory activity with an IC₅₀ of 5 nM. Didesmethylrocaglamide suppresses multiple growth-promoting signaling pathways and induces apoptosis in tumor cells. Antitumor activity .

HY-N4114

Picrocrocin	Apoptosis	Cancer
Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

HY-101404S

DL-Homocysteine thiolactone-d4 hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-N10089

Psiguadial D	Others	Cancer
Psiguadial D is a terpenoid that can be isolated from Psidium guajava, and it has a strong inhibitory effect on the growth of HepG2 cells, with an IC₅₀value of 128.3 nM .

HY-138100

Hyalodendrin (+)-Hyalodendrin	Fungal	Infection
Hyalodendrin ((+)-Hyalodendrin) is a fungal growth inhibitor with inhibitory activity against wood decay fungi. Hyalodendrin has low phytotoxicity, with an acute toxicity (LD50) of 75 mg/kg in mice .

HY-N7989

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside Tellimoside	Others	Others
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Tellimoside) is a flavonol glycoside with strong inhibitory activity against the growth of Microcystis aeruginosa .

HY-122308R

Militarine (Standard)	Others	Metabolic Disease
Militarine (Standard) is the analytical standard of Militarine. This product is intended for research and analytical applications. Militarine, a glycosidic compound isolated from Bletilla striata, exhibits plant growth-inhibitory activity .

HY-N3346

Macrocarpal A 10-epi-Eucarobustol F	Bacterial	Infection
Macrocarpal A (10-epi-Eucarobustol F) is an antibacterial agent, which can be isolated from the leaves of Eucalyptus macrocarpa. Macrocarpal A inhibits the growth of Bacillus subtilis PCI219 (minimum inhibitory concentration below 0.2 µM) and Staphylococcus aureus FDA209P (minimum inhibitory concentration is 0.4 µM) .

HY-Y0729

4-Chlorocinnamic acid	Tyrosinase Bacterial Fungal	Infection
4-Chlorocinnamic acid has inhibitory effects on tyrosinase. 4-Chlorocinnamic acid has antibacterial activity. 4-Chlorocinnamic acid also inhibits Colletotrichum gloeosporioides growth .

HY-N12636

Kagimminol A	Parasite	Infection
Kagimminols A is a cembrene-type diterpenoids and can be isolated from an Okeania sp. marine cyanobacterium. Kagimminols A shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis .

HY-N2483

Hydroprotopine	Others	Cancer
Hydroprotopine is a alkaloid from Hypecoum leptocarpumand. Leptopidine can suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression .

HY-W047478

3-Methylcarbazole NSC 10154	Others	Cancer
3-Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3-Methylcarbazole shows growth inhibitory activity (IC₅₀ of 25 μg/mL) on human fibrosarcoma HT-1080 cells .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

HY-169062

RJF02215	MMP	Cancer
RJF02215 is an MMP-9 inhibitor. RJF02215 has growth-inhibitory activity on the ovarian cancer SKOV3 cell line. RJF02215 can be used for tumor research .

HY-101404R

DL-Homocysteine thiolactone hydrochloride (Standard)	Endogenous Metabolite	Others
DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-N12637

Kagimminol B	Parasite	Infection
Kagimminol B, a cembrene-type diterpenoid, can be isolated from an Okeania sp. marine cyanobacterium. Kagimminol B shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis .

HY-N12430

Marsdenoside A	Others	Cancer
Marsdenoside A (compound 7) is a Marsdenoside isolated from Alocasia genus. Marsdenoside A has a weak growth inhibitory effect on two tumor cell lines, MGC-803 and HT-29, with IC₅₀ >50 μg/mL.

HY-113053

Prostaglandin A1	Endogenous Metabolite Apoptosis	Neurological Disease Inflammation/Immunology Endocrinology Cancer
Prostaglandin A1 is a dehydration derivate of Prostaglandin E1. Prostaglandin A1 exhibits inhibitory activities against tumor growth, inflammation, virus replication, platelet aggregation and excitotoxin-induced neurons apoptosis .

HY-15369

FPA-124	Akt Apoptosis	Cancer
FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC₅₀ of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis .

HY-W178011

Topoisomerase IIα-IN-9 4,4'-Sulfonylbis(2-methylphenol)	Topoisomerase	Cancer
Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC₅₀: 571 μM). Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC₅₀s of 117 μM and 218 μM for K562 and CHO, respectively .

HY-161797

Antibacterial agent 227	Aminoacyl-tRNA Synthetase	Infection
Antibacterial agent 227 (Compd 29) is a SerRS (Seryl-tRNA synthetase) inhibitor. Antibacterial agent 227 has a significant inhibitory effect on the growth of planktonic and biofilm culture of Staphylococcus aureus 25923 with MIC (minimum inhibitory concentration) value of 32 µg/ml. Antibacterial agent 227 can be proposed as effective antiseptic toward multidrug-resistant biofilm-forming S. aureus isolates .

HY-115996

Antitumor agent-51	Others	Cancer
Antitumor agent-51 possesses potent and selective inhibitory for osteosarcoma cell growth and migration with IC₅₀ of 21.9 nM in MNNG/HOS cells. Antitumor agent-51 has a considerable bioavailability and a low toxicity .

HY-W040055A

L-(-)-Neopterin L-erythro-Neopterin	Others	Neurological Disease Metabolic Disease
L-(-)-Neopterin (L-erythro-Neopterin) is a cholinergic receptor that acts as a competitive antagonist, countering the inhibitory effects of pteridine diuretics on the growth of Crithidia fasciculata. L-(-)-Neopterin can be used in research related to the nervous system and purine metabolism .

HY-10949

SMER3	E1/E2/E3 Enzyme	Cancer
SMER3, a Rapamycin enhancer, is a selective Skp1-Cullin-F-box (SCF) ^Met30 ubiquitin ligase inhibitor. SMER3 enhances Rapamycin's growth inhibitory effect by inhibition of SCF ^Met30 .

HY-100338

CNX-500	Btk	Cancer
CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk (IC₅₀ of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn .

HY-115770

8-Methylsulfinyloctyl isothiocyanate	Bacterial	Inflammation/Immunology
8-Methylsulfinyloctyl isothiocyanate, an isothiocyanate, has antimicrobial activity and remarkable inhibitory activity against plant growth . 8-Methylsulfinyloctyl isothiocyanate impair COX-2 mediated inflammatory responses in LPS stimulated raw macrophages .

HY-163561

CARM1-IN-6	Histone Methyltransferase	Cancer
CARM1-IN-6 (iCARM1) is an effective and selective inhibitor of CARM1 with an IC₅₀ value of 12.3 μM. CARM1-IN-6 exhibits cell growth inhibitory activity and can be used in cancer research .

HY-N6842

ArnicolideC	Others	Infection Cancer
ArnicolideC is a sesquiterpene lactone isolated Centipeda minima . ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation .

HY-148777

A031	PROTACs Androgen Receptor	Cancer
A031 is a highly effective PROTAC androgen receptor (AR) degrader with an IC₅₀ value less than 0.25 μM for AR protein degradation. A031 has an inhibitory effect on tumor growth in zebrafish with human prostate cancer (VCaP) .

HY-19536

LLL12	STAT	Cancer
LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. LLL12 enhanced the inhibitory effect of Cisplatin (HY-17394) and Paclitaxel (HY-B0015) on ovarian cancer cell formation, migration, and growth .

HY-N12200

Mollicellin I	Others	Cancer
Mollicellin I (compound 1) is a depsidone. The growth inhibitory activity of Mollicellin I on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines is not significant, with GI₅₀s >10 μg/mL .

HY-N4114R

Picrocrocin (Standard)	Apoptosis	Cancer
Picrocrocin (Standard) is the analytical standard of Picrocrocin. This product is intended for research and analytical applications. Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

HY-101982

Lys-SMCC-DM1 1 Publications Verification Lys-Nε-MCC-DM1	Drug-Linker Conjugates for ADC	Cancer
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer .

HY-N7623

Ursonic acid methyl ester	Others	Cancer
Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED₅₀ values of >100 µg/ml .

HY-108530

MM11253	RAR/RXR	Cancer
MM11253 is a potent and selective RARγ antagonist with an IC₅₀ of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists .

Cat. No.	Product Name	Target	Research Area

HY-12403A

Talfirastide acetate Maximum Cited Publications 9 Publications Verification TXA127 acetate; Angiotensin (1-7) (acetate); Ang-(1-7) (acetate)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

HY-12403

Talfirastide Maximum Cited Publications 9 Publications Verification TXA127; Angiotensin (1-7); Ang-(1-7)	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

HY-P1547

Somatostatin-25	Peptides	Neurological Disease
Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.

HY-P5107

Low molecular weight protamine LMWP	VEGFR	Cancer
Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

Cat. No.	Product Name	Target	Research Area

HY-P99153

Farletuzumab MORAb-003	Antibiotic	Cancer
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101404

DL-Homocysteine thiolactone hydrochloride	Structural Classification Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-122308

Militarine	Bletilla striata (Thunb. ex Murray) Rchb. f. Structural Classification Classification of Application Fields Orchidaceae Source classification Phenols Metabolic Disease Plants Disease Research Fields	Others
Militarine, a glycosidic compound isolated from Bletilla striata, exhibits plant growth-inhibitory activity .

HY-W017401

Benzisothiazolone BIT	Classification of Application Fields Disease Research Fields Cancer	Others
Benzisothiazolone is an isothiazolone fungicide. Benzisothiazolone has growth inhibiting activity against E. coli ATCC 8739 and saccharornyces pombe NCYC 1354. Benzisothiazolone can be used in the study of growth inhibition model .

HY-B1918

(+)-Bornyl acetate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Hamamelidaceae Plants Disease Research Fields Liquidambar formosana Hance	Others
(+)-Bornyl acetate is found in pichtae essential oil (Siberian fir needle oil). (+)-Bornyl acetate has a stronger inhibitory effect on root growth of Arabidopsis seedlings .

HY-N4114

Picrocrocin	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Lridaceae Plants Crocus sativus L. Disease Research Fields Cancer	Apoptosis
Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

HY-129580

Nannochelin B	Structural Classification Microorganisms Antibiotics Source classification	Bacterial Fungal
Nannochelin B is a novel citrate-hydroxamate siderophore with a growth-inhibitory activity against some bacteria and fungi .

HY-N3231

Murraol CM-c2	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Murraya exotica L. Mant.	Lipoxygenase COX
Murraol (CM-c2), a coumarin, can be isolated from the leaves of Madagascar pine cork (Apiaceae). Murraol has cyclooxygenase (COX) and lipoxygenase inhibitory properties and has an inhibitory effect on the growth of cancer cells .

HY-N10278

Pycnophorin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
Pycnophorin significantly inhibits the growth of Bacillus subtilis and Staphyloccocus aureus with equal minimum inhibitory concentration (MIC) values of 25 μM.

HY-N12262

(+)-Epieudesmin	Structural Classification other families Hernandia nymphaeifolia (C. Presl) Kubitzki Source classification Lignans Phenylpropanoids Plants	Bacterial
(+)-Epieudesmin is an antineoplastic agent. (+)-Epieudesmin has marginal cancer cell line inhibitory activities. (+)-Epieudesmin inhibits the growth of Gram-negative pathogen .

HY-123135

Scirpusin B	Bolboschoenus maritimus Source classification Cyperaceae Plants	Others
Scirpusin B (compound 5) is a dimeric antioxidant isolated from Scirpus maritimus L.. Scirpusin B exhibits antitumor, antifungal, insecticidal, and plant growth inhibitory activities.

HY-N10089

Psiguadial D	Structural Classification Terpenoids Sesquiterpenes Source classification Psidium guajava Linn. Myrtaceae Plants	Others
Psiguadial D is a terpenoid that can be isolated from Psidium guajava, and it has a strong inhibitory effect on the growth of HepG2 cells, with an IC₅₀value of 128.3 nM .

HY-138100

Hyalodendrin (+)-Hyalodendrin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Hyalodendrin ((+)-Hyalodendrin) is a fungal growth inhibitor with inhibitory activity against wood decay fungi. Hyalodendrin has low phytotoxicity, with an acute toxicity (LD50) of 75 mg/kg in mice .

HY-N7989

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside Tellimoside	Flavonols Structural Classification Flavonoids other families Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Tellimoside) is a flavonol glycoside with strong inhibitory activity against the growth of Microcystis aeruginosa .

HY-122308R

Militarine (Standard)	Bletilla striata (Thunb. ex Murray) Rchb. f. Structural Classification Orchidaceae Source classification Phenols Plants	Others
Militarine (Standard) is the analytical standard of Militarine. This product is intended for research and analytical applications. Militarine, a glycosidic compound isolated from Bletilla striata, exhibits plant growth-inhibitory activity .

HY-N3346

Macrocarpal A 10-epi-Eucarobustol F	Structural Classification Eucalyptus macrocarpa Hook. Terpenoids Source classification Myrtaceae Diterpenoids Plants	Bacterial
Macrocarpal A (10-epi-Eucarobustol F) is an antibacterial agent, which can be isolated from the leaves of Eucalyptus macrocarpa. Macrocarpal A inhibits the growth of Bacillus subtilis PCI219 (minimum inhibitory concentration below 0.2 µM) and Staphylococcus aureus FDA209P (minimum inhibitory concentration is 0.4 µM) .

HY-N12636

Kagimminol A	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Parasite
Kagimminols A is a cembrene-type diterpenoids and can be isolated from an Okeania sp. marine cyanobacterium. Kagimminols A shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis .

HY-N2483

Hydroprotopine	Alkaloids Classification of Application Fields Corydalis yanhusuo W. T. Wang Source classification Plants Isoquinoline Alkaloids Disease Research Fields Papaveraceae Cancer	Others
Hydroprotopine is a alkaloid from Hypecoum leptocarpumand. Leptopidine can suppress growth and induce cytotoxicity in breast cancer cells and that the cytotoxicity of leptopidine may be related to its inhibitory effect on fatty acid synthase expression .

HY-W047478

3-Methylcarbazole NSC 10154	Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids Cancer	Others
3-Methylcarbazole is an carbazole alkaloid compound with anticancer effects. 3-Methylcarbazole shows growth inhibitory activity (IC₅₀ of 25 μg/mL) on human fibrosarcoma HT-1080 cells .

HY-101404R

DL-Homocysteine thiolactone hydrochloride (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
DL-Homocysteine thiolactone (hydrochloride) (Standard) is the analytical standard of DL-Homocysteine thiolactone (hydrochloride). This product is intended for research and analytical applications. DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-N12637

Kagimminol B	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Parasite
Kagimminol B, a cembrene-type diterpenoid, can be isolated from an Okeania sp. marine cyanobacterium. Kagimminol B shows selective growth-inhibitory activity against the causative agent of human African trypanosomiasis .

HY-N12430

Marsdenoside A	Structural Classification Araceae Cardiacglycosides Source classification Plants Alocasia cucullata (Lour.) Schott Steroids	Others
Marsdenoside A (compound 7) is a Marsdenoside isolated from Alocasia genus. Marsdenoside A has a weak growth inhibitory effect on two tumor cell lines, MGC-803 and HT-29, with IC₅₀ >50 μg/mL.

HY-113053

Prostaglandin A1	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Endogenous Metabolite Apoptosis
Prostaglandin A1 is a dehydration derivate of Prostaglandin E1. Prostaglandin A1 exhibits inhibitory activities against tumor growth, inflammation, virus replication, platelet aggregation and excitotoxin-induced neurons apoptosis .

HY-115770

8-Methylsulfinyloctyl isothiocyanate	Structural Classification Natural Products Classification of Application Fields Source classification Plants Brassicaceae Inflammation/Immunology Disease Research Fields Rorippa indica (L.) Hiern	Bacterial
8-Methylsulfinyloctyl isothiocyanate, an isothiocyanate, has antimicrobial activity and remarkable inhibitory activity against plant growth . 8-Methylsulfinyloctyl isothiocyanate impair COX-2 mediated inflammatory responses in LPS stimulated raw macrophages .

HY-N6842

ArnicolideC	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Euchresta horsfieldii (Lesch.) J. Benn. Source classification Plants Compositae Disease Research Fields Cancer	Others
ArnicolideC is a sesquiterpene lactone isolated Centipeda minima . ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation .

HY-N12200

Mollicellin I	Structural Classification Natural Products Microorganisms Source classification	Others
Mollicellin I (compound 1) is a depsidone. The growth inhibitory activity of Mollicellin I on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines is not significant, with GI₅₀s >10 μg/mL .

HY-N4114R

Picrocrocin (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Lridaceae Plants Crocus sativus L.	Apoptosis
Picrocrocin (Standard) is the analytical standard of Picrocrocin. This product is intended for research and analytical applications. Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells .

HY-113796

Kopsoffinol	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Kopsia pauciflora Hook.f. Plants	Others
Kopsoffinol, a bisindole alkaloid, shows in vitro growth inhibitory activity against human PC-3, HCT-116, MCF-7, and A549 cells and moderate effects in reversing multidrug-resistance in vincristine-resistant human KB cells .

HY-P99153

Farletuzumab MORAb-003	Classification of Application Fields Disease Research Fields Cancer	Antibiotic
Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .

HY-111934

Cymarin	Apocynaceae Structural Classification Classification of Application Fields Cardiacglycosides Source classification Other Diseases Plants Disease Research Fields Apocynum Steroids	Parasite Potassium Channel
Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K ⁺ release (IC₅₀=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant .

HY-N11128

Solidagonic acid	Structural Classification Terpenoids Source classification Diterpenoids Solidago altissima Linnaeus Plants Compositae	Kinesin
Solidagonic acid inhibits HSET motor activity by promoting the conversion from abnormal monopolar to bipolar spindles. Solidagonic acid suppresses fission yeast cell death and enables reversion of the mitotic spindles from a monopolar to bipolar morphology. Solidagonic acid showed the growth inhibitory activity on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam .

HY-N0817

Polyphyllin G	Structural Classification Classification of Application Fields Paris fargesii var. petiolata (Baker ex C.H.Wright) Wang et Tang Cardiacglycosides Source classification Plants Melanthiaceae Inflammation/Immunology Disease Research Fields Saccharides Monosaccharides Steroids	Apoptosis Autophagy Bacterial
Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs) . Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy .

HY-B0856

Validamycin A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Fungal Tyrosinase Antibiotic
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

HY-N10335

Harringtonolide 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Cephalotaxus harringtonia Plants Cephalotaxaceae Inflammation/Immunology Disease Research Fields Cancer	FAK
Harringtonolide is a potent RACK1 inhibitor (IC₅₀=39.66 μM in A375 cells). Harringtonolide inhibits the epithelial-mesenchymal transition (EMT) process and cell proliferation by affecting the interaction between FAK and RACK1. Harringtonolide has plant growth inhibitory, antiviral, anti-inflammatory, and antiproliferation activities .

HY-117872

Sartorypyrone A 20-O-Acetylsartorypyrone D	Structural Classification Microorganisms Terpenoids Source classification Diterpenoids	Fungal
Sartorypyrone A (20-O-Acetylsartorypyrone D) is a monocyclic terpenoid isolated from the soil fungus Neosartorya fischeri. Sartorypyrone A exhibits in vitro growth inhibitory activity against MCF-7, NCI-H460, and A375-C5 cell lines, and has potential anticancer properties.

HY-N3348

Lyoniside	Structural Classification Vaccinium myrtillus Linn. Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Ericaceae	Fungal
Lyoniside is a lignan glycoside with antioxidant, allelopathic and antifungal activities, which can be isolated from the rhizomes and stems of bilberry (Vaccinium myrtillus L.). Lyoniside exhibits radical scavenging properties with an IC₅₀ value of 23 μg/mL in DPPH assay. Lyoniside inhibits the mycelial growth of Fusarium oxysporum and Mucor hiemalis at 50 μg/mL with inhibitory rates of 78% and 80%, respectively .

HY-N3014

Bruceine D 3 Publications Verification	Infection Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr.	Notch Apoptosis Parasite
Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity . Bruceine D has strong anthelmintic activity against D. intermedius with an EC₅₀ value of 0.57 mg/L .

HY-N7160

2-Hydroxy-3-methylanthraquinone	Quinones Structural Classification Anthraquinones Source classification Rubiaceae Plants Hedyotis diffusa Willd.	Src Apoptosis
2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells .

HY-N13059

Waldiomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic
Waldiomycin is an antibiotic that can be isolated from Streptomyces sp. MK844-mF10 that has inhibitory effects on low GC-content Gram-positive bacteria. Waldiomycin inhibits the activity of WalK kinase by targeting its ATP-binding domain, thereby blocking the WalK/WalR signal transduction system, which plays a role in cell growth and division .

HY-119609

Ilicicolin C	Structural Classification Microorganisms Antibiotics Source classification	Bacterial Cholinesterase (ChE)
Ilicicolin C exhibits antibacterial activity against Pseudomonas syringae with IC₅₀ of 28.5 µg/mL. Ilicicolin C exhibits weak inhibitory activities against acetylcholinesterase (AChE) and β-glucuronidase with IC₅₀ of 30-43 µg/mL. Ilicicolin C exhibits weak cytoxicity in human lung fibroblasts with IC₅₀ of 64-120 µg/mL. Ilicicolin C affects seed germination and root tip growth of lettuce .

HY-B0856R

Validamycin A (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Fungal Tyrosinase Antibiotic
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .

HY-N0970

(4Z)-Lachnophyllum lactone	Source classification Erigeron canadensis L. Plants Compositae	Others
(4Z)-Lachnophyllum lactone is a enyne derivative. (4Z)-Lachnophyllum lactone shows growth inhibitory activity against Lemna paucicostata (IC₅₀=104 μM), which is a problematic and invasive weed . (4Z)-Lachnophyllum lactone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N12198

Mollicellin H	Structural Classification Natural Products Microorganisms Source classification	Others
Mollicellin H is a secondary metabolite of the fungus C. brasiliense and has a wide range of biological activities, including immunomodulation, cytotoxicity and anti-tumor effects. The growth inhibitory effects (GI₅₀s) of Mollicellin H on human breast cancer (Bre04), human lung (Lu04) and human neuroma (N04) cell lines are 5.1 μg/mL, 6.5 μg/mL and 2.5 μg/mL respectively .

HY-B1350A

Fusidic acid sodium salt 2 Publications Verification Sodium fusidate; SQ-16360	Infection Triterpenes Structural Classification Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields Cancer	Bacterial Antibiotic Interleukin Related
Fusidic acid sodium salt is an orally available antibacterial agent that inhibits bacterial protein synthesis by preventing the release of translation elongation factor G (EF-G) from ribosomes. Fusidic acid sodium salt inhibits the inhibitory and activating effects of interleukins IL-1 and IL-6 on glucose-induced insulin production and exhibits antidiabetic effects in a rat model. Fusidic acid sodium salt improves the symptoms of colitis in rats and inhibits the growth of Toxoplasma gondii and Listeria monocytogenes EGD in vitro, but not in mice .

HY-W008566

Norharmane Norharman; β-Carboline	Structural Classification Neurological Disease Classification of Application Fields Source classification Pyridine Alkaloids Endogenous metabolite Biological Pesticide Research Indole Alkaloids Agricultural Research Infection Alkaloids Microorganisms Disease Research Fields Cancer	Monoamine Oxidase Endogenous Metabolite
Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-12403A

Talfirastide acetate Maximum Cited Publications 9 Publications Verification TXA127 acetate; Angiotensin (1-7) (acetate); Ang-(1-7) (acetate)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

HY-138098

Sartorypyrone B	Triterpenes Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields Cancer	Others
Sartorypyrone B is a 2β-acetoxyl analogue of chevalone C. Sartorypyrone B is yielded from the ethyl acetate extract of the culture of the marine sponge-associated fungus Neosartorya tsunodae (KUFC 9213). Sartorypyrone B exhibits strong growth inhibitory activity, having GI₅₀s of 17.8, 20.5, and 25.0 μM, respectively, for MCF-7, NCI-H460, and A375-C5. Sartorypyrone B has the potential for the research of breast adenocarcinoma, non-small cell lung cancer, and melanoma diseases .

HY-W008566R

Norharmane (Standard)	Alkaloids Structural Classification Microorganisms Source classification Pyridine Alkaloids Endogenous metabolite Indole Alkaloids	Monoamine Oxidase Endogenous Metabolite
Norharmane (Standard) is the analytical standard of Norharmane. This product is intended for research and analytical applications. Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .

HY-12403

Talfirastide Maximum Cited Publications 9 Publications Verification TXA127; Angiotensin (1-7); Ang-(1-7)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite
Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

HY-125048

Racemomycin B 229-B; Streptothricin D	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.

HY-Y0367R

Maleic Acid (Standard)	Structural Classification Immune System Disorder Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite	Endogenous Metabolite Bacterial
Maleic Acid (Standard) is the analytical standard of Maleic Acid. This product is intended for research and analytical applications. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of *E. coli* and *L. monocytogenes. IC₅₀* & Target: GAD . In Vitro: The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal .

Species:	Human (2) Mouse (1)
Tag:	His (3) Flag (1)
Source:	HEK293 (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70846

	MIA Protein, Human (His) Melanoma-Derived growth Regulatory Protein; Melanoma inhibitory Activity Protein; MIA	Human	E. coli
	MIA proteins exhibit significant growth inhibitory effects on melanoma cells in vitro, extending their effects to various neuroectodermal tumors such as gliomas. In addition to playing an inhibitory role in cell growth, MIA proteins are also involved in molecular interactions, interacting with FASLG and TMIGD2. MIA Protein, Human (His) is the recombinant human-derived MIA protein, expressed by E. coli , with C-6*His labeled tag. The total length of MIA Protein, Human (His) is 107 a.a., with molecular weight of ~14.0 kDa.

HY-P70846A

	MIA Protein, Human (N-His) Melanoma-Derived growth Regulatory Protein; Melanoma inhibitory Activity Protein; MIA	Human	E. coli
	MIA proteins exhibit significant growth inhibitory effects on melanoma cells in vitro, extending their effects to various neuroectodermal tumors such as gliomas. In addition to playing an inhibitory role in cell growth, MIA proteins are also involved in molecular interactions, interacting with FASLG and TMIGD2. MIA Protein, Human (N-His) is the recombinant human-derived MIA protein, expressed by E. coli , with N-6*His labeled tag. The total length of MIA Protein, Human (N-His) is 107 a.a., with molecular weight of ~14.0 kDa.

HY-P700293

	GDF-15 Protein, Mouse (HEK293, His-Flag) growth Differentiation Factor 15; Macrophage inhibitory cytokine 1; GDF-15; MIC-1; NAG-1; PLAB; PTGFB; Gdf15; Sbf	Mouse	HEK293
	The GDF-15 protein regulates food intake, energy balance, and body weight by binding to its receptor GFRAL.This activates GFRAL-expressing neurons in the brainstem, triggering "emergency circuits" in the central parabrachial nucleus and amygdala during stress.GDF-15 Protein, Mouse (HEK293, His-Flag) is the recombinant mouse-derived GDF-15 protein, expressed by HEK293 , with N-8*His, N-Flag labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-101404S

DL-Homocysteine thiolactone-d4 hydrochloride
DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-B0673S

Pirfenidone-d5
Pirfenidone-d₅ is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].

HY-23155S

2-Phenylethyl isothiocyanate-d5

2-Phenylethyl isothiocyanate-d₅ isothiocyanate-d₅ is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83158

	GDF15 Antibody (YA2903) GDF15; MIC1; PDF; PLAB; PTGFB; growth/differentiation factor 15; GDF-15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic	WB	Human
	GDF15 Antibody (YA2903) is a biotin-conjugated non-conjugated IgG antibody, targeting GDF15, with a predicted molecular weight of 34 kDa (observed band size: 34 kDa). GDF15 Antibody (YA2903) can be used for WB experiment in human background.