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minor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (12) Amyloid-β (1) Antibiotic (4) Apoptosis (3) Bacterial (5) Biochemical Assay Reagents (3) COX (3) Dipeptidyl Peptidase (1) DNA Alkylator/Crosslinker (17) DNA Methyltransferase (1) DNA Stain (6) DNA/RNA Synthesis (6) Drug Metabolite (12) Drug-Linker Conjugates for ADC (5) Endogenous Metabolite (15) FLT3 (1) Fluorescent Dye (2) Fungal (2) Glucocorticoid Receptor (1) IFNAR (1) Influenza Virus (1) Insecticide (1) Interleukin Related (1) Isotope-Labeled Compounds (7) Keap1-Nrf2 (2) MDM-2/p53 (1) Microtubule/Tubulin (1) MMP (1) nAChR (3) Orthopoxvirus (1) Parasite (10) PARP (1) Prostaglandin Receptor (1) PROTACs (1) Reactive Oxygen Species (1) SARS-CoV (1) Serotonin Transporter (1) Topoisomerase (1) TSH Receptor (1)
By Research Areas:	Cancer (44) Cardiovascular Disease (1) Endocrinology (3) Infection (21) Inflammation/Immunology (15) Metabolic Disease (14) Neurological Disease (10)

By Targets:

ADC Cytotoxin (12)

Amyloid-β (1)

Antibiotic (4)

Apoptosis (3)

Bacterial (5)

Biochemical Assay Reagents (3)

COX (3)

Dipeptidyl Peptidase (1)

DNA Alkylator/Crosslinker (17)

DNA Methyltransferase (1)

DNA Stain (6)

DNA/RNA Synthesis (6)

Drug Metabolite (12)

Drug-Linker Conjugates for ADC (5)

Endogenous Metabolite (15)

FLT3 (1)

Fluorescent Dye (2)

Fungal (2)

Glucocorticoid Receptor (1)

IFNAR (1)

Influenza Virus (1)

Insecticide (1)

Interleukin Related (1)

Isotope-Labeled Compounds (7)

Keap1-Nrf2 (2)

MDM-2/p53 (1)

Microtubule/Tubulin (1)

MMP (1)

nAChR (3)

Orthopoxvirus (1)

Parasite (10)

PARP (1)

Prostaglandin Receptor (1)

PROTACs (1)

Reactive Oxygen Species (1)

SARS-CoV (1)

Serotonin Transporter (1)

Topoisomerase (1)

TSH Receptor (1)

By Research Areas:

Cancer (44)

Cardiovascular Disease (1)

Endocrinology (3)

Infection (21)

Inflammation/Immunology (15)

Metabolic Disease (14)

Neurological Disease (10)

122

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Ginsenoside Rh7	Others	Others
Ginsenoside Rh7 is a minor saponin isolated from the leaves of Panax ginseng .

Levofloxacin N-oxide	Drug Metabolite	Infection
Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria .

Averantin	Fungal	Infection
Averantin is the minor metabolite of the fungus Cercospora arachidicola . Averantin is an aflatoxin B1 precursor that can be used in the biosynthetic pathway .

DNA crosslinker 3 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 3 (dihydrochloride) (compound 1) is a potent *DNA minor* groove** binder with DNA binding affinity (ΔT_m) of 1.4 °C. DNA crosslinker 3 (dihydrochloride) can be used for researching anticancer .

DNA crosslinker 1 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 1 dihydrochloride (Compound 4) is a potent *DNA minor* groove** binder with DNA binding affinity (ΔT_m) of 1.1 °C. DNA crosslinker 1 dihydrochloride can be used for researching anticancer .

Lexitropsin 1	DNA Alkylator/Crosslinker	Infection
Lexitropsin 1 is a DNA minor groove binder with a delta G degree of 65 kJ/mol at 303 K. Lexitropsin 1 has antiviral activity .

2,6-Dihydroxy-4-methoxyacetophenone	Fungal	Infection
2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea .

DNA crosslinker 4 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 4 (dihydrochloride) is a potent *DNA minor* groove** binder. DNA crosslinker 4 (dihydrochloride) has certain inhibitory activity against cancer cells NCI-H460, A2780 and MCF-7. DNA crosslinker 4 (dihydrochloride) can be used for researching anticancer .

Levofloxacin N-oxide (Standard)	Drug Metabolite	Infection
Levofloxacin N-oxide (Standard) is the analytical standard of Levofloxacin N-oxide. This product is intended for research and analytical applications. Levofloxacin N-oxide is a minor metabolite of Levofloxacin (HY-B0330). Levofloxacin N-oxide does not exhibit significantly genotoxic risks. Levofloxacin is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria .

DNA crosslinker 2 dihydrochloride	DNA Alkylator/Crosslinker	Cancer
DNA crosslinker 2 (dihydrochloride) is a potent *DNA minor* groove** binder with DNA binding affinity (ΔT_m) of 1.2 °C. DNA crosslinker 2 (dihydrochloride) has certain inhibitory activity against cancer cells NCI-H460, A2780 and MCF-7. DNA crosslinker 2 (dihydrochloride) can be used for researching anticancer .

S-MGB-234	DNA/RNA Synthesis Parasite	Infection
S-MGB-234 is a minor groove binder of Animal African Trypanosomiasis (AAT). S-MGB-234 displays excellent in vitro activities against the principal causative organisms of AAT; Trypanosoma congolense, and Trypanosoma vivax. S-MGB-234 does not show cross-resistance with the current diamidine agents and are not internalized via the transporters used by diamidines .

Suberylglycine	Endogenous Metabolite	Metabolic Disease
Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.

Victoxinine	Others	Others
Victoxinine is a metabolite of Bipolaris sp. Victoxinine has minor phytotoxic .

2-O-Desmethyl cisapride	Drug Metabolite	Neurological Disease
2-O-Desmethyl cisapride is a minor Cisapride metabolite .

Lithospermidin B	Biochemical Assay Reagents	Others
Lithospermidin B is a minor pigment that can be isolated from the roots of L. erythrorhizon .

Vilazodone carboxylic acid	Drug Metabolite	Others
Vilazodone carboxylic acid is a vilazodone metabolite observed in both urine (major) and plasma (minor) .

Eprinomectin B1b	Parasite	Infection
Eprinomectin B1b is a minor component and belongs to the avermectin family of insecticides and anthelmintics.

3-Hydroxyhippuric acid	Endogenous Metabolite	Others
3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.

Rebaudioside N	Others	Others
Rebaudioside N is a minor steviol glycoside isolated from the leaves of Stevia rebaudiana Bertoni .

Magnesium salicylate	Others	Inflammation/Immunology
Magnesium salicylate is an orally active analgesic that temporarily relieves minor aches and pains[1].

Rebaudioside S	Others	Others
Rebaudioside S is a minor steviol glycoside that can be isolated from the leaves of Stevia rebaudiana .

Ansatrienin A3	Others	Others
Ansatrienin A3, also known as Mycotrienin, is a minor component of the ansamycin complex produced by Streptomyces collinus.

Rebaudioside G	Others	Others
Rebaudioside G is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni, used for sweeteners research .

SGD-1882 PBD dimer	ADC Cytotoxin	Cancer
SGD-1882 is a cytotoxic, DNA minor-groove crosslinking agent pyrrolobenzodiazepine (PBD) dimer, acting as the payload for ADCs.

Hydrocortisone acetate 1 Publications Verification Hydrocortisone 21-acetate; Cortisol 21-acetate	Glucocorticoid Receptor Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Hydrocortisone acetate (Hydrocortisone 21-acetate) is a corticosteroid used to reduce swelling, itching and pain caused by minor skin irritations or hemorrhoids .

N-Acetylglycine Aceturic acid; Acetamidoacetic acid	Endogenous Metabolite	Others
N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.

Emodin-8-glucoside 1 Publications Verification	Others	Cancer
Emodin-8-glucoside is an anthraquinone derivative isolated from Aloe vera, binds to minor groove of DNA .

Spinosyn D 17-pseudoaglycone	Parasite	Infection
Spinosyn D 17-pseudoaglycone is a hydrolysis product of the minor insecticide component Spinosyn D (HY-125326) .

(–)-Sitagliptin carbamoyl glucuronide	Dipeptidyl Peptidase	Metabolic Disease
(–)-Sitagliptin carbamoyl glucuronide is a minor metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor Sitagliptin (HY-13749).

Fenbendazole sulfone Oxfendazole sulfone; FBZ-SO2	Parasite	Infection
Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .

Dasatinib N-oxide	Drug Metabolite	Cancer
Dasatinib N-oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src/Bcr-Abl inhibitor .

(-)-Catechin gallate 1 Publications Verification (-)-Catechin 3-gallate; (-)-Catechin 3-O-gallate	COX	Cancer
(-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

Licoflavonol	Bacterial	Infection
Licoflavonol, a minor flavone from the roots of Glycyrrhiza uralensis, is an inhibitor of the Salmonella type III secretion system (T3SS) .

(R,S)-Anatabine 2 Publications Verification	Others	Inflammation/Immunology
(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .

Rebaudioside B	Others	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose .

Spinetoram L XDE-175-L; 3'-O-Ethyl spinosyn L	Insecticide	Infection
Spinetoram L (XDE-175-L) is a minor component of Spinetoram. Spinetoram is a kind of green and efficient insecticide with a broad range of action against various insects .

Sibiromycin	DNA Alkylator/Crosslinker Antibiotic	Cancer
Sibiromycin is a naturally produced glycosylated pyrrolobenzodiazepines (PBDs). Sibiromycin is also a potent antitumor antibiotic that binds covalently to DNA in the minor groove at the NH2 of guanine .

Pepsin EC 3.4.23.1	Endogenous Metabolite	Endocrinology
Pepsin is the major pig and human gastric proteases, it is a pepsin-like minor gastric proteolytic enzymes. Pepsin contributes to proteolysis of food proteins in the vertebrate stomach .

β-Nicotyrine	Drug Metabolite	Neurological Disease
β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .

Ivermectin B1b	Parasite SARS-CoV	Infection
Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .

SG3199 2 Publications Verification	DNA Alkylator/Crosslinker ADC Cytotoxin	Cancer
SG3199 is a cytotoxic DNA minor groove interstrand crosslinking pyrrolobenzodiazepine (PBD) dimer. SG3199 is the released warhead component of the ADC payload Tesirine (SG3249) .

20-O-Demethyl-AP3	Microtubule/Tubulin	Infection Cancer
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic .

DC1	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

Duocarmycin GA	ADC Cytotoxin DNA Alkylator/Crosslinker	Cancer
Duocarmycin GA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin GA can be used against multi-agent resistant cell lines.

Cat. No.	Product Name	Type

HY-D1738

DAPI dilactate

Maximum Cited Publications

59 Publications Verification

4',6-Diamidino-2-phenylindole dilactate

Fluorescent Dyes/Probes

DAPI (dilactate) is a blue fluorescent dye that preferentially binds dsDNA and binds to minor groove AT clusters. DAPI (dilactate) is combined with dsDNA, and the fluorescence was enhanced about 20-fold. DAPI (dilactate) can be used to identify the cell cycle and specifically stains the nucleus but not the cytoplasm. DAPI (dilactate) form is more soluble in water than DAPI (dihydrochloride) form.

HY-D0814

DAPI dihydrochloride

Maximum Cited Publications

59 Publications Verification

4',6-Diamidino-2-phenylindole dihydrochloride

Fluorescent Dyes/Probes

DAPI dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells .

HY-D0814A

DAPI (dihydrochloride) (solution)

55+ Cited Publications

4',6-Diamidino-2-phenylindole dihydrochloride (solution)

Fluorescent Dyes/Probes

DAPI dihydrochloride (4',6-Diamidino-2-phenylindole dihydrochloride) (solution) is a DAPI dye. DAPI is a fluorescent dye that can bind strongly to DNA. DAPI binds to the A/T base pairs in the minor groove of double-stranded DNA (1 DAPI molecule can occupy 3 base pairs), which amplifies the fluorescence intensity by about 20 times. By observing the fluorescence intensity, DNA can be quantified. DAPI can also penetrate intact cell membranes and is often used to stain living and fixed cells .

Cat. No.	Product Name	Type

HY-134433A

GDP-L-fucose disodium	Carbohydrates
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .

HY-N7864

Osbond acid

all-cis-4,7,10,13,16-Docosapentaenoic acid

Cell Assay Reagents

Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.

HY-114773

N-Undecanoyl-L-homoserine lactone

Microbial Culture

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.

Cat. No.	Product Name	Target	Research Area

HY-P1240

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat 4 Publications Verification MOG (35-55)	Peptides	Neurological Disease Inflammation/Immunology
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T?cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination .

HY-P1240B

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 4 Publications Verification MOG (35-55) acetate	Peptides	Neurological Disease Inflammation/Immunology
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T?cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate produces a relapsing-remitting neurological disease with extensive plaque-like demyelination .

HY-P1240A

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA 4 Publications Verification MOG (35-55) TFA	Peptides	Neurological Disease Inflammation/Immunology
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA produces a relapsing-remitting neurological disease with extensive plaque-like demyelination .

HY-P4885

Glp-amyloid-β (3-40) peptide (human) AβpE3-40	Amyloid-β	Neurological Disease
Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a minor amounts of pyroglutamate-modified Aβ isolated from from 24-month-old Amyloid precursor protein (APP) transgenic Mice .

Cat. No.	Compare	Product Name	Species	Source

HY-P71525

	Minor allergen Can f 2 protein, Dog (His-SUMO) minor allergen Can f 2; Allergen Dog 2; allergen Can f 2	Dog	E. coli
	The Minor allergen Can f 2 protein is found in tongue epithelial tissue and the parotid gland. Minor allergen Can f 2 protein, Dog (His-SUMO) is the recombinant dog-derived Minor allergen Can f 2 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-113367S

Suberylglycine-d4
Suberylglycine-d₄ is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid[1][2].

HY-Y0069S

N-Acetylglycine-d5
N-Acetylglycine-d₅ is the deuterium labeled N-Acetylglycine. N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics.

HY-16293S

Lurbinectedin-d3
Lurbinectedin-d₃ is deuterium labeled Lurbinectedin. Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively[1].

HY-113367S1

Suberylglycine-d2
Suberylglycine-d₂ is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid[1][2].

HY-133794S

Dasatinib N-oxide-d8
Dasatinib N-oxide-d₈ is the deuterium labeled Dasatinib N-oxide. Dasatinib N-oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src/Bcr-Abl inhibitor[1][2].

HY-N0356S

(+/-)-Catechin Gallate-13C3
(+/-)-Catechin Gallate- ¹³C₃ is the ¹³C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.

HY-W612269S

Isonicotinoyl chloride-d4
Isonicotinoyl chloride-d₄ is the deuterated labeled Isonicotinoyl chloride (HY-W612269). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics .

HY-126047AS

(R,S)-Anatabine-d4
(R,S)-Anatabine-d4 is a deuterated labeled (R,S)-Anatabine . (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use .

HY-B1953S

Thiacloprid-d4
Thiacloprid-d₄ is the deuterium labeled Thiacloprid[1]. Thiacloprid, a chloronicotinyl insecticide, is targeted chiefly to control aphid pest species in orchards and vegetables[1]. Thiacloprid destabilizes DNA. Thiacloprid changes the structure and stability of DNA through binding into the minor groove by hydrophobic or hydrogen interactions[2].

HY-Y0069S1

N-Acetylglycine-d2
N-Acetylglycine-d₂ (Aceturic acid-d₂; Acetamidoacetic acid-d₂) is the deuterated labeled N-Acetylglycine (HY-Y0069). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics .

HY-50936S

Trabectedin-d3

Trabectedin D3 (Ecteinascidin 743 D3) is deuterium labeled Trabectedin. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has tje potential for soft tissue sarcoma and ovarian cancer treatment .

HY-N6937S1

(R,R)-Secoisolariciresinol diglucoside-d6

(R,R)-Secoisolariciresinol diglucoside-d₆ is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .

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Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

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NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

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