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Results for "

relaxant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5-HT Receptor (5) Adrenergic Receptor (1) Apoptosis (6) Autophagy (4) Bradykinin Receptor (1) Calcium Channel (12) Caspase (2) Cholinesterase (ChE) (5) Cytochrome P450 (4) Drug Metabolite (3) Endogenous Metabolite (7) GABA Receptor (7) Gap Junction Protein (1) Glutathione Reductase (1) Guanylate Cyclase (1) iGluR (5) Isotope-Labeled Compounds (9) mAChR (4) nAChR (8) NF-κB (4) Orthopoxvirus (1) PACAP Receptor (1) Parasite (1) PGC-1α (4) Phosphodiesterase (PDE) (2) Potassium Channel (8) Prostaglandin Receptor (1) Serotonin Transporter (2) Sodium Channel (6) TGF-beta/Smad (6)
By Research Areas:	Cancer (13) Cardiovascular Disease (13) Infection (2) Inflammation/Immunology (23) Metabolic Disease (18) Neurological Disease (82)

By Targets:

11β-HSD (1)

5-HT Receptor (5)

Adrenergic Receptor (1)

Apoptosis (6)

Autophagy (4)

Bradykinin Receptor (1)

Calcium Channel (12)

Caspase (2)

Cholinesterase (ChE) (5)

Cytochrome P450 (4)

Drug Metabolite (3)

Endogenous Metabolite (7)

GABA Receptor (7)

Gap Junction Protein (1)

Glutathione Reductase (1)

Guanylate Cyclase (1)

iGluR (5)

Isotope-Labeled Compounds (9)

mAChR (4)

nAChR (8)

NF-κB (4)

Orthopoxvirus (1)

PACAP Receptor (1)

Parasite (1)

PGC-1α (4)

Phosphodiesterase (PDE) (2)

Potassium Channel (8)

Prostaglandin Receptor (1)

Serotonin Transporter (2)

Sodium Channel (6)

TGF-beta/Smad (6)

By Research Areas:

Cancer (13)

Cardiovascular Disease (13)

Infection (2)

Inflammation/Immunology (23)

Metabolic Disease (18)

Neurological Disease (82)

120

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1343

Pridinol mesylate	Cholinesterase (ChE)	Neurological Disease
Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-121966

Riparin Riparin III	Others	Cancer
Riparin is a nonspecific smooth muscle relaxant. Riparin inhibits CaCl2-induced contractions in a reversible and non-competitive manner and can be used in spasmolytic studies .

HY-121130

Dacuronium 17-hydroxypancuronium	Others	Neurological Disease
Dacuronium (17-hydroxypancuronium) is a steroid muscle relaxant .

HY-121340

Emylcamate	Others	Neurological Disease
Emylcamate is a potent muscle relaxant. Emylcamate has the potential for the research of neurological diseases .

HY-125463

ANQ9040	nAChR	Neurological Disease
ANQ9040 is a steroidal relaxant. ANQ9040 is a relatively low-affinity and non-depolarizing nicotinic antagonist .

HY-127147

Fazadinium bromide AH 8165 bromide	Others	Others
Fazadinium bromide (AH 8165 bromide) is a neuromuscular blocking agent, that can prevent the muscle contraction. Fazadinium bromide can be used as a muscle relaxant during anesthesia .

HY-B1343A

Pridinol	Cholinesterase (ChE)	Neurological Disease
Pridinol is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-B0262S

Methocarbamol D5	Sodium Channel	Metabolic Disease
Methocarbamol-d₅ is deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel[1].

HY-165544

Decamethonium chloride	Others	Neurological Disease
Decamethonium chloride is a depolarizing neuromuscular blocking agent that can be used to study the mechanism of action of muscle relaxants .

HY-167650

Fletazepam	Others	Neurological Disease
Fletazepam is a benzodiazepine derivative with sedative, anxiolytic and muscle relaxant effects. Fletazepam can be utilized in neurological research .

HY-B1343R

Pridinol mesylate (Standard)	Cholinesterase (ChE)	Neurological Disease
Pridinol (mesylate) (Standard) is the analytical standard of Pridinol (mesylate). This product is intended for research and analytical applications. Pridinol mesylate is an orally active and potent central anticholinergic agent, and acts as muscle relaxant .

HY-P3875

[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2 BM-PACAP	PACAP Receptor	Neurological Disease Metabolic Disease
[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect .

HY-B0262

Methocarbamol 1 Publications Verification	Sodium Channel	Neurological Disease
Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research .

HY-128469

Inaperisone	GABA Receptor	Neurological Disease
Inaperisone is a centrally acting muscle relaxant. Inaperisone can inhibit the micturition reflex by acting indirectly on GABAB receptors in the brainstem .

HY-149554

17-Phenyl trinor Prostaglandin F2α dimethyl amide Bimatoprost dimethyl amide	Others	Neurological Disease
17-Phenyl trinor Prostaglandin F2α dimethyl amide (Bimatoprost dimethyl amide), a 1-OH cyclopentane heptanoic acid, 2-(cycloalkyl or arylalkyl) derivative, is a smooth muscle relaxant. 17-Phenyl trinor Prostaglandin F2α dimethyl amide has the potential for glaucoma research .

HY-113920A

Azumolene EU4093 free base	Calcium Channel	Metabolic Disease
Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene is a ryanodine receptor (RyR) modulator and inhibits the calcium-release through ryanodine receptor. Azumolene can be used for malignant hyperthermia research .

HY-B0262R

Methocarbamol (Standard)	Sodium Channel	Neurological Disease
Methocarbamol (Standard) is the analytical standard of Methocarbamol. This product is intended for research and analytical applications. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research .

HY-B0429

Pancuronium dibromide	nAChR	Neurological Disease
Pancuronium dibromide, a bis-quaternary steroid, is a neuromuscular relaxant. Pancuronium dibromide inhibits neuromuscular transmission by competing with acetylcholine for binding sites on nACh receptors. Pancuronium dibromide also inhibits cardiac muscarinic receptors and has a sympathomimetic action .

HY-117162

S 1432	Others	Neurological Disease
S 1432 is a central nervous system depressant with anticonvulsant and muscle relaxant effects. S 1432 significantly reduces acetylcholine levels in the striatum, making it potentially valuable for research in the development of psychotropic drugs .

HY-B0118A

Vecuronium bromide ORG NC 45	nAChR	Neurological Disease Cancer
Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .

HY-B1700A

Mivacurium dichloride	nAChR	Neurological Disease
Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-107944

Chlorphenesin carbamate Maolate; U 19646	Others	Neurological Disease
Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation . Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels . Antinociceptive effect .

HY-B0118AR

Vecuronium bromide (Standard)	nAChR	Neurological Disease Cancer
Vecuronium (bromide) (Standard) is the analytical standard of Vecuronium (bromide). This product is intended for research and analytical applications. Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .

HY-B0252

Hydrochlorothiazide 3 Publications Verification HCTZ	TGF-beta/Smad Potassium Channel	Cardiovascular Disease Metabolic Disease Cancer
Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .

HY-124047

RX 67668	Cholinesterase (ChE)	Neurological Disease
RX 67668 is a potent cholinesterase inhibitor with an IC₅₀ of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue .

HY-N0301

Thiocolchicoside	GABA Receptor	Neurological Disease Inflammation/Immunology
Thiocolchicoside is a competitive γ-aminobutyric acid type A (GAB_AA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .

HY-B1700AR

Mivacurium dichloride (Standard)	nAChR	Neurological Disease
Mivacurium (dichloride) (Standard) is the analytical standard of Mivacurium (dichloride). This product is intended for research and analytical applications. Mivacurium dichloride is a benzylisoquinoline derivative and is a short-acting non-depolarizing neuromuscular blocking agent and skeletal muscle relaxant. Mivacurium dichloride couples with the nAChR to reduce or inhibit the depolarizing effect of acetylcholine on the terminal disc of the muscle cell .

HY-B0678

Metaxalone AHR438; NSC170959	NF-κB PGC-1α	Neurological Disease Inflammation/Immunology
Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

HY-B1283

Mephenesin	iGluR	Neurological Disease
Mephenesin is an NMDA receptor antagonist. Mephenesin is also a central muscle relaxant with antianxiety, muscle-paralyzing and anticonvulsant effects. Mephenesin acts directly on the skeletal muscle fibres to produce skeletal muscle relaxation. Mephenesin is promising for research of spasticity or as an adjunctive treatment of painful muscle spasm .

HY-N0301R

Thiocolchicoside (Standard)	GABA Receptor	Neurological Disease Inflammation/Immunology
Thiocolchicoside (Standard) is the analytical standard of Thiocolchicoside. This product is intended for research and analytical applications. Thiocolchicoside is a competitive γ-aminobutyric acid type A (GAB_AA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties .

HY-B0252S3

Hydrochlorothiazide-15N2,13C,d2 HCTZ-¹⁵N₂,¹³C,d₂	Potassium Channel TGF-beta/Smad Isotope-Labeled Compounds	Cardiovascular Disease Metabolic Disease Cancer
Hydrochlorothiazide- ¹⁵N₂, ¹³C,d₂ is ¹⁵N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .

HY-110289

(R)-Citalopram oxalate	Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism .

HY-110289R

(R)-Citalopram oxalate (Standard)	Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram (oxalate) (Standard) is the analytical standard of (R)-Citalopram (oxalate). This product is intended for research and analytical applications. (R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism .

HY-Y0337A

L-Cysteine hydrochloride 4 Publications Verification	Endogenous Metabolite	Metabolic Disease
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

HY-W052144

(±) Anabasine 1 Publications Verification	Endogenous Metabolite	Others
(±) Anabasine is a biphasic muscle relaxant.

HY-B1230

Camylofine	mAChR	Neurological Disease
Camylofin is an antimuscarinic, is a smooth muscle relaxant

HY-100159

Ipenoxazone MLV-6976; NC-1200	Others	Neurological Disease
Ipenoxazone is a potent and centrally acting muscle relaxant.

HY-107276

Yubeinine	Others	Inflammation/Immunology
Yubeinine is an alkaloid with tracheal relaxant effects .

HY-Y0337AR

L-Cysteine hydrochloride (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

HY-101237

DHBP dibromide Diheptylviologen dibromide	Calcium Channel	Cardiovascular Disease Neurological Disease
DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

HY-100159A

Ipenoxazone hydrochloride MLV-6976 hydrochloride; NC-1200 hydrochloride	Others	Neurological Disease
Ipenoxazone (MLV-6976) hydrochloride is a potent and centrally acting muscle relaxant.

HY-101808

Doxefazepam SAS-643	GABA Receptor	Neurological Disease
Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsan and skeletal muscle relaxant properties.

HY-W052144S

(±) Anabasine-d4 dihydrochloride	Isotope-Labeled Compounds Endogenous Metabolite	Others
(±) Anabasine-d₄ (dihydrochloride) is deuterium labeled (±) Anabasine. (±) Anabasine is a biphasic muscle relaxant.

HY-B1139A

Tolperisone	Others	Neurological Disease
Tolperisone, a centrally acting muscle relaxant, is utilized for alleviating symptoms of spasticity and muscle spasms.

HY-106888A

CS-722	Endogenous Metabolite	Neurological Disease
CS-722 is a centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex[1]. CS-722 inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-B1462

Chlorzoxazone 2 Publications Verification	Cytochrome P450	Inflammation/Immunology
Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort.

HY-14895B

Fabomotizole di(hydrochloride) CM346 dihydrochloride	Others	Neurological Disease
Fabomotizole dihydrochloride is an anxiolytic agent. Fabomotizole dihydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

HY-106888

CS-722 Free base	Endogenous Metabolite	Neurological Disease
CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex . CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-17033

Rocuronium Org-9426	Others	Neurological Disease
Rocuronium (Org-9426) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia.

HY-B0353

Chlormezanone	GABA Receptor	Neurological Disease
Chlormezanone resembles benzodiazepine. The action of Chlormezanone is similar to benzodiazepine-type agents. Chlormezanone is used as an anxiolytic and a muscle relaxant.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0337A

L-Cysteine hydrochloride 4 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

HY-W052144

(±) Anabasine 1 Publications Verification	Alkaloids Piperidine Alkaloids Structural Classification Other disease Classification of Application Fields Source classification Disease markers Other Diseases Pyridine Alkaloids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±) Anabasine is a biphasic muscle relaxant.

HY-107276

Yubeinine	Alkaloids Piperidine Alkaloids other families Classification of Application Fields Source classification Plants Disease Research Fields Inflammation/Immunology	Others
Yubeinine is an alkaloid with tracheal relaxant effects .

HY-N2842

α-Amyrin acetate	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology	Others
α-Amyrin acetate, a natural triterpenoid, has anti-inflammatory activity, antispasmodic profile and the relaxant effect .

HY-N2005

Cycleanine	Alkaloids Structural Classification Classification of Application Fields Source classification Plants Cissampelos pareira Menispermaceae Inflammation/Immunology Disease Research Fields Alkaloid Dimers	Calcium Channel Apoptosis
Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway .

HY-N4323

14-Deoxyandrographolide	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-Y0337AR

L-Cysteine hydrochloride (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

HY-106888

CS-722 Free base	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CS-722 Free base is a synthesized centrally acting muscle relaxant, and has a muscle relaxant activity and depressant effectson the spinal reflex . CS-722 Free base inhibits spontaneous inhibitory postsynaptic currents and excitatory postsynaptic currents in hippocampal cultures probably by an inhibition of both sodium and calcium currents .

HY-N7648

Atherosperminine Atherospermine	Infection Alkaloids Classification of Application Fields Source classification Fissistigma glaucescens Plants Annonaceae Disease Research Fields	Parasite
Atherosperminine（Atherospermine）is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC₅₀ of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC₅₀ of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis .

HY-N4323R

14-Deoxyandrographolide (Standard)	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Calcium Channel Apoptosis Caspase
14-Deoxyandrographolide (Standard) is the analytical standard of 14-Deoxyandrographolide. 14-Deoxyandrographolide is a diterpene with calcium channel blocking activity and acts as a uterine smooth muscle relaxant. 14-Deoxyandrographolide stimulates the release of nitric oxide (NO) in endothelial cells. 14-Deoxyandrographolide gradually desensitizes liver cells to TNF-α mediated apoptosis by inducing the release of TNFRSF1A .

HY-N2913

Ayanin	Psychotria serpens Linn. Structural Classification Natural Products Classification of Application Fields Rubiaceae Plants Inflammation/Immunology Disease Research Fields	Phosphodiesterase (PDE)
Ayanin is a bioflavonoid isolated from Psychotria serpens. Ayanin is a non-selective phosphodiesterase_1-4 inhibitor and can be used for the study of respiratory disease,such as allergic asthma et al .

Cat. No.	Product Name	Chemical Structure

HY-B0262S1

Methocarbamol-d3
Methocarbamol-d₃ is the deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3].

HY-B0252S

Hydrochlorothiazid-d2

Hydrochlorothiazid-d₂ is the deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].

HY-B1462S

Chlorzoxazone-d3
Chlorzoxazone-d₃ is the deuterium labeled Chlorzoxazone. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes.Chlorzoxazone is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans.

HY-B0262S

Methocarbamol D5
Methocarbamol-d₅ is deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel[1].

HY-B0252S3

Hydrochlorothiazide-15N2,13C,d2

Hydrochlorothiazide- ¹⁵N₂, ¹³C,d₂ is ¹⁵N and deuterated labeled Hydrochlorothiazide (HY-B0252). Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect .

HY-W052144S

(±) Anabasine-d4 dihydrochloride
(±) Anabasine-d₄ (dihydrochloride) is deuterium labeled (±) Anabasine. (±) Anabasine is a biphasic muscle relaxant.

HY-B0740S

Cyclobenzaprine-d3 hydrochloride
Cyclobenzaprine-d₃ (hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride. Cyclobenzaprine hydrochloride (MK130 hydrochloride) is a skeletal muscle relaxant and a central nervous system (CNS) depressant.

HY-B1462S1

Chlorzoxazone-13C
Chlorzoxazone- ¹³C is the ¹³C labeled Chlorzoxazone[1]. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[2].

HY-B1139S

Tolperisone-d10 hydrochloride

Tolperisone-d₁₀ (hydrochloride) is the deuterium labeled Tolperisone hydrochloride. Tolperisone hydrochloride is a centrally acting muscle relaxant, is indicated for use in the treatment of pathologically increased tone of the cross-striated muscle caused by neurological diseases (damage of the pyramidal tract, multiple sclerosis, myelopathy, encephalomyelitis) and of spastic paralysis and other encephalopathies manifested with muscular dystonia.

HY-B0262S2

Methocarbamol-13C,d3
Methocarbamol- ¹³C,d₃ is the ¹³C- and deuterium labeled Methocarbamol. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research[1][2][3].

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-B0252S2

Hydrochlorothiazide-13C6

Hydrochlorothiazide- ¹³C₆ is the ¹³C labeled Hydrochlorothiazide[1]. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[2][3][4].

HY-B1901S

Eperisone-d10 hydrochloride

Eperisone-d₁₀ (hydrochloride) is the deuterium labeled Eperisone hydrochloride. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3].

HY-B0252S1

Hydrochlorothiazid-13C,d2

Hydrochlorothiazid- ¹³C,d₂ is the ¹³C- and deuterium labeled Hydrochlorothiazide. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].

HY-B0678S

Metaxalone-d3

Metaxalone-d₃ is the deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

HY-B0678S1

Metaxalone-d6

Metaxalone-d₆ is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

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