2. Gene
  3. Cdk9 - cyclin-dependent kinase 9 Gene

Cdk9 - cyclin-dependent kinase 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362110 | Gene type: protein coding

About Cdk9

Biased expression in Spleen (RPKM 124.8), Thymus (RPKM 121.4) and 9 other tissues.

Summary

Enables chromatin binding activity. Involved in positive regulation of cardiac muscle hypertrophy and response to xenobiotic stimulus. Located in nucleus. Orthologous to human CDK9 (cyclin dependent kinase 9). [provided by Alliance of Genome Resources, Apr 2022]

Cdk9 Products(1)

mRNA Protein Name
NM_001007743.1 NP_001007744.1 cyclin-dependent kinase 9

Cdk9 Protein Structure

STKc_CDK9

STKc_CDK9: cd07865 (5 - 314)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 9

cell division protein kinase 9

cyclin-dependent kinase 9 (CDC2-related kinase)

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16297A Abemaciclib Inhibitor 99.94% Yes
HY-10492 Dinaciclib Inhibitor 99.36% Yes
HY-16297 Abemaciclib methanesulfonate Inhibitor 99.95% Yes
Clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Phase
HY-112088 AZD4573 Inhibitor 99.98% Phase 2
HY-50940 AT7519 Inhibitor 99.76% Phase 2
HY-103712A Samuraciclib hydrochloride Inhibitor 99.98% Phase 2
HY-101212 Fadraciclib Inhibitor 99.78% Phase 2
HY-13914 Roniciclib Inhibitor 98.09% Phase 2
HY-112272A Lerociclib dihydrochloride Inhibitor 98.11% Phase 2
HY-103712B Samuraciclib hydrochloride hydrate Inhibitor 99.08% Phase 2
HY-50943 AT7519 Hydrochloride Inhibitor 99.42% Phase 2
HY-112272 Lerociclib Inhibitor 98.35% Phase 2
HY-16559A Riviciclib Inhibitor / Phase 2
HY-138293 SY-5609 Inhibitor 99.66% Phase 1
HY-10008 SNS-032 Inhibitor 99.54% Phase 1
HY-137478A KB-0742 dihydrochloride Inhibitor 99.24% Phase 1
HY-10012 AZD-5438 Inhibitor 99.85% Phase 1
HY-11001 PHA-793887 Inhibitor 99.25% Phase 1
HY-12871B Atuveciclib Inhibitor 99.80% Phase 1
HY-15504 RGB-286638 Inhibitor 99.70% Phase 1
HY-12422 Voruciclib Inhibitor 99.77% Phase 1
HY-15504A RGB-286638 free base Inhibitor 98.07% Phase 1
HY-12422A Voruciclib hydrochloride Inhibitor 99.23% Phase 1
HY-50940A AT7519 TFA Inhibitor 98.53% Phase 1
Pre-clinical Phase
Bioactive Molecules (105)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103618 THZ531 Inhibitor 99.86% Unkown
HY-103248 Toyocamycin Inhibitor 99.90% Unkown
HY-12214A NVP-2 Inhibitor 99.60% Unkown
HY-103019 (+)-Enitociclib Inhibitor 99.66% Unkown
HY-130665 TL12-186 Inhibitor 99.63% Unkown
HY-101257 YKL-5-124 Inhibitor 98.79% Unkown
HY-111388A SEL120-34A monohydrochloride Inhibitor 99.29% Unkown
HY-18340 (R)​-​CR8 Inhibitor 99.61% Unkown
HY-11009 CGP60474 Inhibitor 99.23% Unkown
HY-130709 PROTAC CDK2/9 Degrader-1 Inhibitor 99.85% Unkown
HY-123954 BTX-A51 Inhibitor 98.58% Unkown
HY-15878 LDC000067 Inhibitor 98.00% Unkown
HY-12445 Asnuciclib Inhibitor 99.76% Unkown
HY-13266A BS-181 hydrochloride Inhibitor 99.80% Unkown
HY-13461A PHA-767491 hydrochloride Inhibitor 98.06% Unkown
HY-18340A (R)-CR8 trihydrochloride Inhibitor 98.95% Unkown
HY-112626 CDK12-IN-2 Inhibitor 99.36% Unkown
HY-103628 PROTAC CDK9 Degrader-1 Inhibitor 98.03% Unkown
HY-12280 THZ2 Inhibitor 99.03% Unkown
HY-X0150 JSH-150 Inhibitor 98.36% Unkown
HY-144117 GFB-12811 Inhibitor 98.00% Unkown
HY-12293 LY2857785 Inhibitor 99.92% Unkown
HY-117203A CDK12-IN-E9 Inhibitor 99.97% Unkown
HY-119940 MC180295 Inhibitor 98.89% Unkown
HY-13231 CDK9-IN-1 Inhibitor 98.52% Unkown
HY-111388B SEL120-34A hydrochloride Inhibitor 99.98% Unkown
HY-16462 CDK9-IN-2 Inhibitor 99.37% Unkown
HY-16559 Riviciclib hydrochloride 98.89% Unkown
HY-143584 AZ5576 Inhibitor 99.88% Unkown
HY-103019B (-)-Enitociclib Inhibitor 99.69% Unkown
HY-101257B YKL-5-124 TFA Inhibitor 99.44% Unkown
HY-13033 CDK-IN-2 Inhibitor 98.97% Unkown
HY-123955 Casein Kinase inhibitor A86 Inhibitor 99.26% Unkown
HY-18944 FIT-039 Inhibitor 99.56% Unkown
HY-103646 CK7 Inhibitor 99.72% Unkown
HY-15241 NVP-LCQ195 Inhibitor 98.91% Unkown
HY-12871 Atuveciclib Racemate Inhibitor 98.48% Unkown
HY-102039 CDK9-IN-8 Inhibitor 99.65% Unkown
HY-126251 CDK9-IN-7 Inhibitor 98.05% Unkown
HY-139980 CDK9-IN-13 Inhibitor 99.22% Unkown
HY-153260 TP-1287 Inhibitor 95.10% Unkown
HY-103712C Samuraciclib hydrochloride hydrate Inhibitor 99.88% Unkown
HY-100950 ABC1183 Inhibitor 99.19% Unkown
HY-153556 GW297361 Inhibitor 98.13% Unkown
HY-130852 CDK9-IN-11 Inhibitor 96.03% Unkown
HY-124639 CDK9 inhibitor HH1 Inhibitor 97.97% Unkown
HY-100429 CAN508 Inhibitor 99.59% Unkown
HY-X0009 JSH-009 Inhibitor / Unkown
HY-111427 CDK8/19-IN-1 Inhibitor 98.03% Unkown
HY-139328 CDK12-IN-5 Inhibitor 99.01% Unkown
HY-162037 CDDD11-8 Inhibitor 99.62% Unkown
HY-130850 CDK9-IN-10 Inhibitor 98.00% Unkown
HY-12843 Bohemine Inhibitor 98.93% Unkown
HY-115714 CDK9-IN-12 Inhibitor 99.65% Unkown
HY-143585 CDK9-IN-14 Inhibitor 99.91% Unkown
HY-13266 BS-181 Inhibitor 98.10% Unkown
HY-X0009A JSH-009 dimaleate Inhibitor / Unkown
HY-111388 SEL120-34A Inhibitor / Unkown
HY-14372 BS-194 Inhibitor 99.36% Unkown
HY-139329 CDK12-IN-6 Inhibitor 98.09% Unkown
HY-13461 PHA-767491 Inhibitor / Unkown
HY-151436 ZLMT-12 Inhibitor / Unkown
HY-130981 FN-1501-propionic acid / Unkown
HY-110368 BS-181 dihydrochloride Inhibitor / Unkown
HY-131063 CDK6/9-IN-1 Inhibitor / Unkown
HY-130001 CDK9-IN-9 Inhibitor / Unkown
HY-103712 Samuraciclib Inhibitor / Unkown
HY-149963 PROTAC CDK9 degrader-6 Inhibitor / Unkown
HY-168518 PROTAC CDK9 degrader-9 Degrader / Unkown
HY-136841 SLM6 Inhibitor / Unkown
HY-149495 CP-07 Degrader / Unkown
HY-155153 CDK9-IN-24 Inhibitor / Unkown
HY-147771 ZLWT-37 Inhibitor / Unkown
HY-111356 IIIM-290 Inhibitor / Unkown
HY-137478 KB-0742 Inhibitor / Unkown
HY-149962 PROTAC CDK9 degrader-5 Inhibitor / Unkown
HY-151898 CDK4/6-IN-14 Inhibitor / Unkown
HY-112811 PROTAC CDK9 degrader-2 Inhibitor / Unkown
HY-150641 CDK-IN-9 Inhibitor / Unkown
HY-155787 SHR5428 Inhibitor / Unkown
HY-151984 CDK9-IN-22 Inhibitor / Unkown
HY-161463 CDK2-IN-28 Inhibitor / Unkown
HY-150573 CDK2-IN-12 Inhibitor / Unkown
HY-162619 CDK9-IN-33 Inhibitor / Unkown
HY-151878 CDK7-IN-20 Inhibitor / Unkown
HY-162706 BSJ-5-63 Degrader / Unkown
HY-157980 CDK9-IN-32 Inhibitor / Unkown
HY-156083 CDK9-IN-28 Inhibitor / Unkown
HY-163856 CDK7-IN-30 Inhibitor / Unkown
HY-149870 PROTAC CDK9 degrader-8 Inhibitor / Unkown
HY-161595 CDK5-IN-4 Inhibitor / Unkown
HY-123034 CDKI-83 Inhibitor / Unkown
HY-153426 CDK9-IN-23 Inhibitor / Unkown
HY-161379 CLZX-205 Inhibitor / Unkown
HY-150562 CDK9-IN-19 Inhibitor / Unkown
HY-161768 VCC972839:01 Inhibitor / Unkown
HY-139327 CDK12-IN-4 Inhibitor / Unkown
HY-156795 PROTAC CDK9/CycT1 Degrader-2 Inhibitor / Unkown
HY-145408 CDK7/9-IN-1 Inhibitor / Unkown
HY-142696 CDK6/PIM1-IN-1 Inhibitor / Unkown
HY-112450 Olomoucine II Inhibitor / Unkown
HY-119120 JTK-101 Inhibitor / Unkown
HY-123826 CCT68127 Inhibitor / Unkown
HY-112403 (S)-Roscovitine Inhibitor / Unkown
HY-164619 CDK9-IN-34 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk9 NCBI NCBI:1025