2. Gene
  3. MIA - MIA SH3 domain containing Gene

MIA - MIA SH3 domain containing Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CD-RAP

Gene ID: 8190 | Gene type: protein coding

About MIA

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:40,775,160-40,777,490 (from NCBI)

This gene has 7 transcripts (splice variants), 163 orthologues and 10 paralogues. Biased expression in stomach (RPKM 20.5), salivary gland (RPKM 4.7) and 2 other tissues.

Summary

Predicted to enable growth factor activity. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within cell-matrix adhesion. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

MIA Products(2)

mRNA Protein Name
NM_001202553.2 NP_001189482.1 melanoma-derived growth regulatory protein precursor
NM_006533.4 NP_006524.1 melanoma-derived growth regulatory protein precursor

MIA Protein Structure

SH3_2

SH3_2: Variant SH3 domain (48 - 110)

  • 0
  • 100
  • 131 a.a.
Protein Preferred Names Protein Names

melanoma-derived growth regulatory protein

melanoma inhibitory activity

Recombinant MIA Proteins

Cat. No. Product Name Accession Purity
HY-P70846 MIA Protein, Human (His) Q16674 (G25-Q131) ≥95%
HY-P70846A MIA Protein, Human (N-His) Q16674 (G25-Q131) ≥95%

Related Diseases

Diseases Alias
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
Familial Isolated Hypoparathyroidism

Fih
Melanoma, Uveal

Uveal Melanoma

Choroidal Melanoma

Melanoma Of Uvea

Iris Melanoma

Malignant Melanoma Of Choroid

Malignant Melanoma Of Iris
Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

Melanoma, Malignant

CMM1

Melanoma, Cutaneous Malignant

Cmm

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-130149 Adagrasib Inhibitor 99.93% Phase 3
HY-112089 Naporafenib Inhibitor 99.86% Phase 2
HY-13323 CX-5461 Inhibitor 99.49% Phase 1
HY-13323A CX-5461 dihydrochloride Inhibitor 99.41% Phase 1
HY-148012 SOP1812 98.37% Phase 1
Pre-clinical Phase
Bioactive Molecules (60)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13594 Chlorin e6 98.31% Unkown
HY-145926 MRTX0902 Inhibitor 99.75% Unkown
HY-145321 TMX-4100 Inhibitor 98.18% Unkown
HY-114189 GW284543 Inhibitor 99.94% Unkown
HY-141477 RM-018 Inhibitor 98.03% Unkown
HY-112776A BN82002 hydrochloride Inhibitor 99.36% Unkown
HY-155874 ZNL-05-044 Inhibitor 99.91% Unkown
HY-144310 DX3-213B Inhibitor 99.68% Unkown
HY-16967 MM41 Inhibitor 99.92% Unkown
HY-112776 BN82002 Inhibitor / Unkown
HY-154313 Spiclomazine Inhibitor 99.95% Unkown
HY-160023 D3S-001 Inhibitor / Unkown
HY-137046 Nek2-IN-4 / Unkown
HY-146459 Akt1-IN-1 Inhibitor 99.74% Unkown
HY-153090 Transketolase-IN-4 Inhibitor 99.59% Unkown
HY-157762 GPX4-IN-9 / Unkown
HY-146544 KRAS inhibitor-14 Inhibitor / Unkown
HY-146546 KRAS inhibitor-16 Inhibitor / Unkown
HY-108436 Deltazinone 1 Inhibitor / Unkown
HY-114189A GW284543 hydrochloride Inhibitor / Unkown
HY-122152 Spiclomazine hydrochloride Inhibitor / Unkown
HY-123597 NSC 109555 / Unkown
HY-142946 KRAS G12C inhibitor 44 Inhibitor / Unkown
HY-144311 OXPHOS-IN-1 Inhibitor / Unkown
HY-146475 KRAS inhibitor-17 Inhibitor / Unkown
HY-146476 KRAS inhibitor-18 Inhibitor / Unkown
HY-146533 KRAS inhibitor-12 Inhibitor / Unkown
HY-146537 KRAS G12C inhibitor 47 Inhibitor / Unkown
HY-146543 KRAS inhibitor-13 Inhibitor / Unkown
HY-146545 KRAS inhibitor-15 Inhibitor / Unkown
HY-147838 Nampt-IN-9 Inhibitor / Unkown
HY-149076 hGAPDH-IN-1 / Unkown
HY-149510 MET/PDGFRA-IN-1 / Unkown
HY-149511 MET/PDGFRA-IN-2 / Unkown
HY-149607 SHP2-IN-22 Inhibitor / Unkown
HY-151968 KRAS G12C inhibitor 57 Inhibitor / Unkown
HY-155065 SB-1295 / Unkown
HY-155356 YN14 Degrader / Unkown
HY-156549 KRAS G12C inhibitor 61 Inhibitor / Unkown
HY-156716 MASTL-IN-2 Inhibitor 98.49% Unkown
HY-159511 Hedgehog IN-7 Inhibitor / Unkown
HY-159577 Nic-15 Modulator / Unkown
HY-161320 EGFR-IN-105 / Unkown
HY-161425 Antitumor agent-149 Inducer / Unkown
HY-161618 MJ04 Inhibitor / Unkown
HY-161858 EpskA21 / Unkown
HY-162627 LDHA-IN-6 Inhibitor / Unkown
HY-162629 LDHA-IN-7 Inhibitor / Unkown
HY-162763 FLQY2 Inducer / Unkown
HY-162873 MEK/RAF-IN-1 Inhibitor / Unkown
HY-168577 KRAS G12D inhibitor 25 Inhibitor / Unkown
HY-D2380 H2S probe 1 / Unkown
HY-P2698 1-Alaninechlamydocin / Unkown
HY-RS08419 MIA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08420 MIA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08421 MIA3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-120966 NCX 2121 / Unkown
HY-127045 Akuammicine Agonist / Unkown
HY-164039 Talorasib / Unkown
HY-165245 SBI-183 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MIA RGD RGD:620883
Mus musculus MIA MGD MGI:109615
Macaca fascicularis MIA NCBI NCBI:102118191
Macaca mulatta MIA NCBI NCBI:114669743
Others MIA NCBI