Search Result

Results for "

anti-pyretic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Apoptosis (16) Bacterial (14) Calcium Channel (1) Caspase (3) COX (62) Dengue virus (1) DNA/RNA Synthesis (1) Drug Metabolite (6) Endogenous Metabolite (11) Ferroptosis (1) Flavivirus (1) Fungal (2) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (1) Histone Acetyltransferase (6) Influenza Virus (2) Interleukin Related (1) Isotope-Labeled Compounds (14) Lipoxygenase (1) Melanocortin Receptor (2) MMP (3) NF-κB (1) NO Synthase (1) Parasite (6) PGE synthase (3) Phosphodiesterase (PDE) (1) Phospholipase (1) Prostaglandin Receptor (6) RANKL/RANK (1) Reactive Oxygen Species (4) SARS-CoV (1) TNF Receptor (3)
By Research Areas:	Cancer (38) Cardiovascular Disease (6) Endocrinology (2) Infection (10) Inflammation/Immunology (124) Metabolic Disease (10) Neurological Disease (14)

By Targets:

5-HT Receptor (1)

Apoptosis (16)

Bacterial (14)

Calcium Channel (1)

Caspase (3)

COX (62)

Dengue virus (1)

DNA/RNA Synthesis (1)

Drug Metabolite (6)

Endogenous Metabolite (11)

Ferroptosis (1)

Flavivirus (1)

Fungal (2)

HIF/HIF Prolyl-Hydroxylase (2)

Histamine Receptor (1)

Histone Acetyltransferase (6)

Influenza Virus (2)

Interleukin Related (1)

Isotope-Labeled Compounds (14)

Lipoxygenase (1)

Melanocortin Receptor (2)

MMP (3)

NF-κB (1)

NO Synthase (1)

Parasite (6)

PGE synthase (3)

Phosphodiesterase (PDE) (1)

Phospholipase (1)

Prostaglandin Receptor (6)

RANKL/RANK (1)

Reactive Oxygen Species (4)

SARS-CoV (1)

TNF Receptor (3)

By Research Areas:

Cancer (38)

Cardiovascular Disease (6)

Endocrinology (2)

Infection (10)

Inflammation/Immunology (124)

Metabolic Disease (10)

Neurological Disease (14)

140

Inhibitors & Agonists

Screening Libraries

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8471

Niazinin	Parasite SARS-CoV	Infection Inflammation/Immunology
Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC₅₀ value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity .

HY-106823

Tebufelone NE-11740	COX Lipoxygenase	Neurological Disease Inflammation/Immunology
Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties .

HY-B0811

Salicylamide 1 Publications Verification 2-Hydroxybenzamide	Others	Inflammation/Immunology
Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent.

HY-U00063

Tiopinac RS 40974	Others	Neurological Disease Inflammation/Immunology
Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory and anti-pyretic agent .

HY-N6656

6-Hydroxycoumarin	Fungal Bacterial	Inflammation/Immunology Cancer
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-B0578

Loxoprofen 1 Publications Verification	COX	Cardiovascular Disease Inflammation/Immunology Cancer
Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC₅₀s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity .

HY-17491

Proquazone RU 43-715; Sandoz-43-715	Others	Inflammation/Immunology
Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID). unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent .

HY-B0811R

Salicylamide (Standard)	Others	Inflammation/Immunology
Salicylamide (Standard) is the analytical standard of Salicylamide. This product is intended for research and analytical applications. Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent.

HY-N15147

Panax saponin C	DNA/RNA Synthesis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Panax saponin C is a ginsenoside found in Ginseng with biological activities including regulatory effects on immunomodulation, protection functions in the central nervous and cardiovascular systems, anti-diabetic, anti-aging, anti-carcinogenic, anti-fatigue, anti-pyretic, anti-stress, boosting physical vitality, and promotion of DNA, RNA, and protein synthesis activities .

HY-B0578S

Loxoprofen-d4	Isotope-Labeled Compounds COX	Inflammation/Immunology
Loxoprofen-d₄ is deuterium labeled Loxoprofen. Loxoprofen is a non-steroidal anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively[1][2].

HY-B0578A

Loxoprofen sodium 1 Publications Verification	COX	Cardiovascular Disease Inflammation/Immunology Cancer
Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC₅₀s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor activity .

HY-B0578B

Loxoprofen sodium (dihydrate)	COX	Cardiovascular Disease Inflammation/Immunology Cancer
Loxoprofen sodium dihydrate is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium dihydrate is a nonselective COX inhibitor with IC₅₀s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium dihydrate can reduce atherosclerosis and shows antitumor activity .

HY-B0578R

Loxoprofen (Standard)	COX	Cardiovascular Disease Inflammation/Immunology Cancer
Loxoprofen (Standard) is the analytical standard of Loxoprofen. This product is intended for research and analytical applications. Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC₅₀s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity .

HY-105142

M-5011	Others	Inflammation/Immunology
M-5011 is a potent and orally active anti-inflammatory agent. M-5011 shows potent antinociceptive effects and inhibits kaolin (HY-W115786)-induced writhing. M-5011 decreases peritoneal 6-keto-PGF1 alpha levels with low ulcerogenic activities. M-5011 shows anti-inflammatory and anti-pyretic effects and analgesic effect .

HY-U00152

Aminochlorthenoxazin ICI 350	Others	Inflammation/Immunology
Aminochlorthenoxazin is an antipyretic and analgesic agent.

HY-W176576

Falimint	Others	Inflammation/Immunology
Falimint is an antipyretic and analgesic compound .

HY-B1428

2-Ethoxybenzamide Ethenzamide	Others	Others
2-Ethoxybenzamide is widely used as an antipyretic and analgesic.

HY-17476

Carbasalate calcium	Others	Inflammation/Immunology
Carbasalate calcium is an anti-inflammatory, antipyretic, and analgesic agent.

HY-B0440

Tenoxicam Ro-12-0068	COX	Inflammation/Immunology
Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.

HY-101432

Fenclozic acid ICI-54450; Acidum fenclozicum; Mialex	Others	Neurological Disease
Fenclonic acid is an orally active analgesic, antipyretic and anti-inflammatory agente .

HY-N0517

Erianin 4 Publications Verification	Bacterial	Neurological Disease Cancer
Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

HY-119466

Broperamole	Others	Inflammation/Immunology
Broperamole is an anti-inflammatory and antipyretic agent. Broperamole has systemic and toical antiinflammatory activity .

HY-W016034

Acetaminophen glucuronide sodium salt p-Acetamidophenyl β-D-glucuronide sodium salt; p-AAPG sodium salt	Others	Infection
Acetaminophen glucuronide is a safe and effective antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver and kidney .

HY-B0906

Bucetin 3-Hydroxy-p-butyrophenetidide	Others	Others
Bucetin (3-Hydroxy-p-butyrophenetidide) is an antipyretic compound and can also be used in pain relief studies.

HY-119517

Seclazone	Others	Inflammation/Immunology
Seclazone, a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally active .

HY-105808

Furobufen	Others	Neurological Disease Inflammation/Immunology
Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue .

HY-105630

Pipebuzone LD-4644	Others	Inflammation/Immunology
Pipebuzone (LD 4644) is an anti-inflammatory, antipyretic and analgesic agent. Pipebuzone plays an important raol in rheumatic diseases .

HY-B1054

Famprofazone	Others	Inflammation/Immunology
Famprofazone is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series, has analgesic, anti-inflammatory, and antipyretic effects.

HY-B1015

Etosalamide Ethosalamide	Others	Inflammation/Immunology
Etosalamide (Ethosalamide) is an *antipyretic* and analgesic agent. Etosalamide has anti-inflammatory activity and can be used for allergic disease research .

HY-12384

Tenosal	Others	Inflammation/Immunology
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties.

HY-133588

4-Formylaminoantipyrine	Endogenous Metabolite	Metabolic Disease
4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo .

HY-106325

AA 2379	Others	Inflammation/Immunology
AA 2379 is an orally active antirheumatic agent. AA 2379 has antiinflammatory, antipyretic activities and reduces pain sensation .

HY-B0440S

Tenoxicam-d3 Ro-12-0068-d₃	Isotope-Labeled Compounds COX	Inflammation/Immunology
Tenoxicam-d₃ is the deuterium labeled Tenoxicam. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.

HY-121132

Butibufen	Others	Inflammation/Immunology
Butibufen is an orally active non-steroidal compound. Butibufen shows analgesic and antipyretic properties. Butibufen can be used for the research of inflammation .

HY-17479A

Amfenac Sodium Hydrate	Others	Inflammation/Immunology
Amfenac Sodium Hydrate is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium Hydrate can be used for the research of acute and chronic inflammation .

HY-105939

Isofezolac LM 22070	PGE synthase	Inflammation/Immunology
Isofezolac (LM 22070) is a non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin-synthetase. Isofezolac anti-inflammatory, and antipyretic properties .

HY-B1137

Ramifenazone Isopropylaminoantipyrine	Bacterial	Inflammation/Immunology
Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities .

HY-N2399

Diffractaic acid	Apoptosis	Inflammation/Immunology Cancer
Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research . Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta .

$Diffractaic acid$

HY-17482

Difenpiramide Z-876	Others	Inflammation/Immunology
Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .

HY-B0440R

Tenoxicam (Standard)	COX	Inflammation/Immunology
Tenoxicam (Standard) is the analytical standard of Tenoxicam. This product is intended for research and analytical applications. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.

HY-B1428R

2-Ethoxybenzamide (Standard)	Others	Others
2-Ethoxybenzamide (Standard) is the analytical standard of 2-Ethoxybenzamide. This product is intended for research and analytical applications. 2-Ethoxybenzamide is widely used as an antipyretic and analgesic.

HY-17479B

Amfenac sodium AHR 5850 sodium	Others	Inflammation/Immunology
Amfenac sodium (AHR 5850 sodium) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac sodium can be used for the research of acute and chronic inflammation .

HY-17479

Amfenac	Others	Inflammation/Immunology
Amfenac (AHR 5850) is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac can be used for the research of acute and chronic inflammation .

HY-U00157

Meseclazone W2395; NSC297623	Others	Inflammation/Immunology
Meseclazone (W2395;NSC297623) exhibits inhibitory potency of secondary phase ADP aggregation. Meseclazone possesses anti-inflammatory, analgesic and antipyretic activity.

HY-121046S

Flunixin-d3 Sch 14714-d₃	COX	Inflammation/Immunology
Flunixin-d₃ is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity[1][2].

HY-N0564

Notopterol 1 Publications Verification	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML) .

HY-N0517R

Erianin (Standard)	Bacterial	Neurological Disease Cancer
Erianin (Standard) is the analytical standard of Erianin. This product is intended for research and analytical applications. Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

HY-B0171

Antipyrine 3 Publications Verification Phenazone; Phenazon	Others	Inflammation/Immunology
Antipyrine (Phenazone) is an antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine has been widely used in assessment of hepatic oxidative capacity .

HY-N12647

cis-Hinkiresinol	Others	Infection Inflammation/Immunology
cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation .

HY-A0273S

Propyphenazone-d3	COX	Inflammation/Immunology
Propyphenazone-d₃ is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

Cat. No.	Product Name

HY-L130

Non-steroidal Anti-Inflammatory Compound Library

616 compounds

Non-steroidal anti-inflammatory drugs (NSAIDs) are members of a therapeutic drug class with potent anti-inflammatory, analgesic and antipyretic activity, and are among the most widely used drugs worldwide. The most prominent NSAIDs are aspirin, ibuprofen, and naproxen.

The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX), based on which NSAIDs can be classified into two types: non-selective and COX-2 selective. Most NSAIDs are non-selective and inhibit both COX-1 and COX-2 activity.

MCE offers a unique collection of 616 non-steroidal compounds with identified anti-inflammatory activity. MCE non-steroidal anti-inflammatory library is a useful tool for the study of anti-inflammatory drugs and pharmacology.

Cat. No.	Product Name	Target	Research Area

HY-P0252

α-MSH 10+ Cited Publications α-Melanocyte-Stimulating Hormone	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-P0252A

α-MSH TFA 10+ Cited Publications α-Melanocyte-Stimulating Hormone TFA	Melanocortin Receptor	Neurological Disease Metabolic Disease Inflammation/Immunology
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH TFA is a post-translational derivative of pro-opiomelanocortin (POMC) .

HY-P4834

Acetyl-α-MSH (11-13)	Peptides	Inflammation/Immunology
Acetyl-α-MSH (11-13) is the acetylated C-terminal tripeptide of α-MSH with antipyretic and anti-inflammatory activities .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8471

Niazinin	Structural Classification Natural Products Classification of Application Fields Moringa oleifera Lam. Source classification Moringaceae Plants Inflammation/Immunology Disease Research Fields	Parasite SARS-CoV
Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC₅₀ value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity .

HY-B0811

Salicylamide 1 Publications Verification 2-Hydroxybenzamide	Alkaloids Monophenols Microorganisms Classification of Application Fields Other Alkaloids Source classification Phenols Inflammation/Immunology Disease Research Fields	Others
Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent.

HY-N6656

6-Hydroxycoumarin	Structural Classification Monophenols other families Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Fungal Bacterial
6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity .

HY-N0517

Erianin 4 Publications Verification	Structural Classification Natural Products Monophenols Orchidaceae Source classification Phenols Plants Dendrobium nobile Lindl.	Bacterial
Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

HY-133588

4-Formylaminoantipyrine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo .

HY-N2399

Diffractaic acid	Monophenols Classification of Application Fields Usnea diffracta Vain. Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields Inflammation/Immunology Usneaceae	Apoptosis
Diffractaic acid, a major constituent of U. longissimi, acts as an effective proapoptotic agent in various disorders research . Diffractaic acid is the analgesic and antipyretic component of Usnea diffracta .

$Diffractaic acid$

HY-N0564

Notopterol 1 Publications Verification	Structural Classification Neurological Disease Classification of Application Fields Source classification Coumarins Phenylpropanoids Kleinia odora (Forssk.) DC. Umbelliferae Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML) .

HY-B0811R

Salicylamide (Standard)	Alkaloids Monophenols Microorganisms Other Alkaloids Source classification Phenols	Others
Salicylamide (Standard) is the analytical standard of Salicylamide. This product is intended for research and analytical applications. Salicylamide is an inhibitor of microsomal UDP-glucuronosyltransferase. Salicylamide is an analgesic and anti-pyretic agent.

HY-N15147

Panax saponin C	Panax ginseng C. A. Meyer Structural Classification Natural Products Source classification Plants Araliaceae	DNA/RNA Synthesis
Panax saponin C is a ginsenoside found in Ginseng with biological activities including regulatory effects on immunomodulation, protection functions in the central nervous and cardiovascular systems, anti-diabetic, anti-aging, anti-carcinogenic, anti-fatigue, anti-pyretic, anti-stress, boosting physical vitality, and promotion of DNA, RNA, and protein synthesis activities .

HY-N0517R

Erianin (Standard)	Structural Classification Natural Products Monophenols Orchidaceae Source classification Phenols Plants Dendrobium nobile Lindl.	Bacterial
Erianin (Standard) is the analytical standard of Erianin. This product is intended for research and analytical applications. Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

HY-N12647

cis-Hinkiresinol	Structural Classification Liliaceae Source classification Phenols Polyphenols Anemarrhena asphodeloides Bunge Plants	Others
cis-Hinkiresinol is a bioactive constituent of Rhizoma anemarrhenae. Rhizoma anemarrhenae is reprted to have anti-pathogenic microorganism, hypoglycemic effects, anti-inflammatory, antipyretic effects and anti-platelet aggregation .

HY-N1984

Artemisic acid Qing Hao acid; Artemisinic acid; Arteannuic acid	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Artemisia carvifolia Buch.-Ham. ex Roxb. Metabolic Disease Plants Compositae Inflammation/Immunology Disease Research Fields	Bacterial
Artemisinic acid (Qing Hao acid), an amorphane sesquiterpene isolated from Artemisia annua L., possesses a variety of pharmacological activity, such as antimalarial activity, anti-tumor activity, antipyretic effect, antibacterial activity, allelopathy effect and anti-adipogenesis effect .

HY-N0055

Chlorogenic acid 10+ Cited Publications 3-O-Caffeoylquinic acid; Heriguard; NSC-407296	Structural Classification Caprifoliaceae Classification of Application Fields Lonicera japonica Thunb. Anti-aging Source classification Plants Endogenous metabolite Infection Human Gut Microbiota Metabolites Microorganisms Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Inflammation/Immunology Disease Research Fields Cancer	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-133588R

4-Formylaminoantipyrine (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
4-Formylaminoantipyrine (Standard) is the analytical standard of 4-Formylaminoantipyrine. This product is intended for research and analytical applications. 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo .

HY-N0564R

Notopterol (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Kleinia odora (Forssk.) DC. Umbelliferae Plants	Apoptosis
Notopterol (Standard) is the analytical standard of Notopterol. This product is intended for research and analytical applications. Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML) .

HY-N7514

Strictosidinic acid	Alkaloids other families Source classification Plants Indole Alkaloids	5-HT Receptor
Strictosidinic acid, an orally active glycoside indole monoterpene alkaloid isolated from Psychotria myriantha leaves, inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice .

HY-N7926

Pentadecane	Structural Classification Natural Products Kaempferia galanga L. Source classification Plants Zingiberaceae	Parasite
Pentadecane is a floral volatile antimalarial agent that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. The IC₅₀s of Pentadecane against promastigotes and amastigotes are 65.3 μM and 60.5 μM, respectively. Pentadecane also has anti-inflammatory, analgesic, and antipyretic activities .

HY-N0055R

Chlorogenic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Caprifoliaceae Simple Phenylpropanols Lonicera japonica Thunb. Source classification Phenols Polyphenols Phenylpropanoids Plants Endogenous metabolite	HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Bacterial Influenza Virus Endogenous Metabolite
Chlorogenic acid (Standard) is the analytical standard of Chlorogenic acid. This product is intended for research and analytical applications. Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .

HY-66005

Acetaminophen Maximum Cited Publications 43 Publications Verification Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide	Structural Classification Alkaloids Monophenols Classification of Application Fields Other Alkaloids Source classification Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields	COX Histone Acetyltransferase Endogenous Metabolite Bacterial Parasite Ferroptosis
Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 25.8 μM; is a widely used antipyretic and analgesic agent. . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor . Acetaminophen induces ferroptosis and leads to acute liver injury in mice model .

HY-N3187

Nimbin	Other Terpenoids Infection Structural Classification other families Neurological Disease Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	Flavivirus Dengue virus Fungal Bacterial Histamine Receptor
Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier .

HY-N7926R

Pentadecane (Standard)	Structural Classification Natural Products Kaempferia galanga L. Source classification Plants Zingiberaceae	Parasite
Pentadecane (Standard) is the analytical standard of Pentadecane. This product is intended for research and analytical applications. Pentadecane is a floral volatile antimalarial agent that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. The IC50s of Pentadecane against promastigotes and amastigotes are 65.3 μM and 60.5 μM, respectively. Pentadecane also has anti-inflammatory, analgesic, and antipyretic activities .

HY-N1746

(2S)-2'-Methoxykurarinone 2'-O-Methylkurarinone	Structural Classification Classification of Application Fields Source classification Metabolic Disease Sophora flavescens Aiton Plants Flavonoids Leguminosae Flavonones Phenols Polyphenols Inflammation/Immunology Disease Research Fields	RANKL/RANK
(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells .

HY-N3945

Glaucine O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396	Infection Alkaloids Structural Classification other families Classification of Application Fields Source classification Plants Isoquinoline Alkaloids Glaucium flavum Inflammation/Immunology Disease Research Fields Papaveraceae	Phosphodiesterase (PDE) Calcium Channel MMP NF-κB
Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 (PDE4), with a K_i of 3.4 µM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB, leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer .

HY-B0367

Lornoxicam Chlortenoxicam; Ro 13-9297	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Apoptosis COX NO Synthase Interleukin Related Prostaglandin Receptor TNF Receptor
Lornoxicam (Chlortenoxicam) is an orally active oxycontin nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, antipyretic and anticancer activities. Lornoxicam exhibits good inhibitory effects on both COX-1 and COX-2 (COX-1: IC₅₀=0.005 μM; COX-2:IC₅₀=0.008 μM) and inhibits the production of NO by iNOS (IC₅₀=65 μM) and the proinflammatory cytokine IL-6 (IC₅₀=54 μM). Lornoxicam also inhibits tumor cell proliferation and migration and induces tumor cell apoptosis. Lornoxicam can be used in the study of inflammatory pain, colorectal cancer and breast cancer .

Cat. No.	Product Name	Chemical Structure

HY-A0273S

Propyphenazone-d3
Propyphenazone-d₃ is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

HY-17479BS

Amfenac-d5 sodium
Amfenac-d₅ sodium is deuterated-labeled Amfenac sodium. Amfenac Sodium is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac Sodium can be used for the research of acute and chronic inflammation .

HY-B0171S

Antipyrine-d3
Antipyrine-d₃ is the deuterium labeled Antipyrine. Antipyrine (Phenazone) is an antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine has been widely used in assessment of hepatic oxidative capacity[1][2].

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0578S

Loxoprofen-d4
Loxoprofen-d₄ is deuterium labeled Loxoprofen. Loxoprofen is a non-steroidal anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC50s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively[1][2].

HY-B0440S

Tenoxicam-d3
Tenoxicam-d₃ is the deuterium labeled Tenoxicam. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.

HY-121046S

Flunixin-d3
Flunixin-d₃ is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity[1][2].

HY-B1279AS

Metamizole-d3 sodium
Metamizole-d3 sodium is the deuterium labeled Metamizole sodium. Metamizole sodium is a non-opioid compound with excellent analgesic and antipyretic effects. Metamizole sodium is a cyclooxygenase-3 (COX-3) inhibitor .

HY-17479S

Amfenac-d5
Amfenac-d₅ is the deuterium labeled Amfenac. Amfenac is an orally active and potent anti-inflammatory compound possessing antipyretic and analgesic properties. Amfenac can be used for the research of acute and chronic inflammation .

HY-B1137S

Ramifenazone-d7
Ramifenazone-d₇ is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities[1][2].

HY-17361S

Etofenamate-d4
Etofenamate-d₄ is the deuterium labeled Etofenamate. Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3].

HY-B0476S

Phenacetin-d5
Phenacetin-d₅ is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[1][2][3].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-78131AS

(S)-(+)-Ibuprofen D3
(S)-(+)-Ibuprofen-d₃ is a deuterium labeled (S)-(+)-Ibuprofen. (S)-(+)-Ibuprofen is the S(+)-enantiomer of Ibuprofen that inhibits COX-1 and COX-2 activity with IC50s of 2.1 μM and 1.6 μM. (S)-(+)-Ibuprofen has analgesic, antiinflammatory and antipyretic effects[1][2].

HY-B0476S1

Phenacetin-13C
Phenacetin- ¹³C is the ¹³C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].

HY-B0363S

Nimesulide D5
Nimesulide-d₅ is a deuterium labeled Nimesulide. Nimesulide is a selective COX-2 inhibitor, with IC50s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties[1][2].

HY-10582S

Flurbiprofen-d3

Flurbiprofen-d₃ is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].

HY-10582S1

Flurbiprofen-d5

Flurbiprofen-d₅ is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].

HY-66005S4

Acetaminophen-13C2,15N
Acetaminophen- ¹³C₂, ¹⁵N is the ¹³C and ¹⁵N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].

HY-10582S3

Flurbiprofen-d4

Flurbiprofen-d₄ is deuterated labeled Flurbiprofen (HY-10582). Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer .

HY-66005S3

Acetaminophen-13C6
Acetaminophen-13C6 (Paracetamol-13C6) is the 13C-labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .

HY-10582S2

Flurbiprofen-13C,d3

Flurbiprofen- ¹³C,d₃ is the ¹³C- and deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].

HY-135731AS

4-Methylamino antipyrine-d3 hydrochloride

4-Methylamino antipyrine-d₃ (hydrochloride) is deuterium labeled 4-Methylamino antipyrine (hydrochloride). 4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. Metamizole is an nonopioid analgesic agent and can be used for pain and fever[1][2][3]. 4-Methylamino antipyrine hydrochloride has analgesic, antipyretic, and relatively weak antiinflammatory properties[2].

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-B1138S

Fenbufen-d9

Fenbufen-d₉ (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC50s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor[1][2][3][4][5].

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