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Results for "

azide compound

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) ADC Cytotoxin (1) ADC Linker (10) Adenosine Receptor (1) Amyloid-β (2) Androgen Receptor (1) Apoptosis (4) Aryl Hydrocarbon Receptor (1) Bacterial (9) Bcl-2 Family (1) Bcr-Abl (1) Biochemical Assay Reagents (24) CD73 (1) Cytochrome P450 (1) Deubiquitinase (1) Dipeptidyl Peptidase (2) DNA/RNA Synthesis (6) Drug Derivative (1) Drug-Linker Conjugates for ADC (1) E3 Ligase Ligand-Linker Conjugates (9) EGFR (2) Eukaryotic Initiation Factor (eIF) (2) Ferroptosis (1) FGFR (5) Fluorescent Dye (5) Free Fatty Acid Receptor (1) Fungal (2) G Protein-coupled Receptor Kinase (GRK) (1) GCGR (1) Glutaminase (1) Glyoxalase (GLO) (1) GPR119 (2) HCV Protease (3) HDAC (1) Histone Demethylase (1) HIV (1) IFNAR (1) iGluR (1) Influenza Virus (1) Interleukin Related (1) JAK (2) MAP4K (1) MDM-2/p53 (3) mGluR (1) Mixed Lineage Kinase (2) Monoamine Oxidase (3) Necroptosis (2) NEKs (1) NF-κB (1) Nucleoside Antimetabolite/Analog (3) Parasite (1) PI3K (1) Potassium Channel (1) PPAR (1) Prion Protein (1) Progesterone Receptor (1) PROTAC Linkers (5) PROTAC-Linker Conjugates for PAC (1) PROTACs (2) Ras (3) Reactive Oxygen Species (1) RET (1) RIP kinase (1) Ser/Thr Protease (1) Src (1) STAT (2) TNF Receptor (1) Toll-like Receptor (TLR) (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (55) Cardiovascular Disease (5) Endocrinology (1) Infection (20) Inflammation/Immunology (9) Metabolic Disease (6) Neurological Disease (13)
Click Chemistry:	ADC Synthesis (3) Labeling and Fluorescence Imaging (4) DBCO (3) PROTAC Synthesis (7) Azide (32) BCN (1) Tetrazine (2) Alkynes (38)
Oligonucleotides:	Nucleotides and their Analogs (4)

136

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W006187

2-Amino-2-(p-tolyl)acetic acid	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

HY-151656

15-Azido-pentadecanoic acid 1 Publications Verification Azido Palmitic Acid	ADC Linker	Others
15-Azido-pentadecanoic acid is a click chemistry reagent containing an azide group. Azido Palmitic Acid can be used to identify and characterize post-translationally palmitylated proteins with using a simple and robust two-step labeling and detection technique . 15-Azido-pentadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D1506

Fl-DIBO	Fluorescent Dye	Others
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to *azide* compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-160077

Pomalidomide-CO-C5-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-CO-C5-azide (Compound PA) is a ligand for E3 ligase bearing a bioorthogonal group azide. Pomalidomide-CO-C5-azide can be used to synthesize PROTACs with anticancer activity .

HY-13443B

Exendin-4-Lys-azide TFA	GCGR	Cardiovascular Disease Metabolic Disease Cancer
Exendin-4-Lys-azide TFA (Compound Ex40) is an azide derivative of Exendin-4-Lys-azide, Exendin-4, which can be used for coupling/click chemistry .

HY-161133

Lenalidomide 4'-PEG1-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. .

HY-139341

Pomalidomide 4'-alkylC3-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC .

HY-139343

Pomalidomide 4'-alkylC2-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-alkylC2-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC2-azide can be used in the synthesis of PROTAC .

HY-156379

Biotin-PEG8-Alkyne	Biochemical Assay Reagents	Others
Biotin-PEG8-Alkyne is an azide reactive compound .

HY-161131

Lenalidomide 4'-alkyl-C3-azide	E3 Ligase Ligand-Linker Conjugates	Inflammation/Immunology
Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .

HY-151719

Azidoacetic Acid 2-Azidoacetic acid	ADC Linker	Others
Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-147621

FGFR-IN-6	FGFR	Cancer
FGFR-IN-6 (Compound 5) is a FGFR inhibitor . FGFR-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130652

Pomalidomide 4'-PEG3-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach . Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-136554

WYC-210	Drug Derivative	Cancer
WYC-210, a Tazarotene derivative, is a retinoid compound with lower anticancer activity . WYC-210 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W145647

2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide	Biochemical Assay Reagents	Others
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl Azide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-112597

Mavodelpar free acid REN001 free acid; HPP593 free acid; Pparδ agonist	PPAR	Metabolic Disease
Mavodelpar free acid is a PPARδ agonist extracted from patent US20180071304, compound example 10. Mavodelpar (free acid) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139332

Pomalidomide 4'-PEG6-azide	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-75970

Boc-Propargylamine N-Boc-Propargylamine	Biochemical Assay Reagents	Others
N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W127601

Lard oil	Biochemical Assay Reagents	Others
Lard oil is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Lard oil is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W004104

4-Ethynylanisole	Biochemical Assay Reagents	Others
4-Ethynylanisole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylanisole is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007423

3-Ethynylaniline	Biochemical Assay Reagents	Others
3-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145595

Ferroptosis inducer-1	Ferroptosis	Cancer
Ferroptosis inducer-1 (compound BX-3a) is a Ferroptosis inducer with antitumor potential . Ferroptosis inducer-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W123012

APN-Azide 3-(4-Azidophenyl)propiolonitrile	Fluorescent Dye
APN-Azide (3-(4-Azidophenyl)propiolonitrile) is a codon-active compound that can achieve specific labeling of target molecules in biological systems through its unique chemical structure. APN-Azide can be used for bioimaging and the development of molecular probes to study biological processes within cells.

HY-W004660

4-Ethynylaniline	Biochemical Assay Reagents	Others
4-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007533

4-Ethynylbenzoic acid	Biochemical Assay Reagents	Others
4-Ethynylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-34604

3-Ethynylpyridine	Biochemical Assay Reagents	Others
3-Ethynylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylpyridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-157573

N-Acetylmuramic acid-azide	Bacterial	Infection
N-Acetylmuramic acid-azide (Compound 2) is a derivative of N-acetylaminoacetic acid (NAM) in bacterial peptidoglycan. Incorporated into bacterial peptidoglycan during biosynthesis .

HY-132846

Vepafestinib TAS0953/HM06	RET	Others Cancer
Vepafestinib (TAS0953/HM06; compound 6) is a RET inhibitor (extracted from patent WO2019039439) . Vepafestinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-146653

Glyoxalase I inhibitor 1	Glyoxalase (GLO)	Cancer
Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC₅₀ of 26 nM . Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-146650

LpxC-IN-9	Bacterial	Infection Cardiovascular Disease
LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects . LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1850

Sulfo-Cy7.5 azide	Fluorescent Dye	Others
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W110146

(3aS,4S,6aR)-Biotin-PEG4-Alkyne	Biochemical Assay Reagents	Others
(3aS,4S,6aR)-Biotin-PEG4-Alkyne is an azide reactive compound .

HY-148908

TNF-α-IN-8	TNF Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases . TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-147237

LpxC-IN-10	Bacterial	Infection
LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection . LpxC-IN-10 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-115414

Bis-propargyl-PEG8	PROTAC Linkers	Cancer
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126192

Pittsburgh Compound B PiB; 6-OH-BTA-1	Amyloid-β	Neurological Disease
Pittsburgh Compound B (PiB) is a PET tracer for Aβ deposition in Alzheimer's disease (AD), with high affinity and specificity. Through click chemistry modification (introducing a PEG3 linker and an alkyne group at the 6-hydroxy position of Pittsburgh Compound B to generate a clickable Pittsburgh Compound B derivative, followed by covalent conjugation with azide-labeled fluorescent dyes or affinity tags via copper-catalyzed azide-alkyne cycloaddition (CuAAC)), Pittsburgh Compound B and its conjugates can be used for fluorescence imaging, ultrastructural studies, and the enrichment and characterization of Aβ complexes. Pittsburgh Compound B holds great potential in Alzheimer's disease research .

HY-111642

3'-Azido-3'-deoxy-beta-L-uridine	Nucleoside Antimetabolite/Analog	Others
3'-Azido-3'-deoxy-beta-L-uridine (Compound 25) is a nucleoside derivative. 3'-Azido-3'-deoxy-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132137B

5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine	DNA/RNA Synthesis	Others
5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 5 in patent document WO2004018497A2. It contains an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC) .

HY-153362

HPK1-IN-34	MAP4K	Cancer
HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC₅₀ of <100 nM . HPK1-IN-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007542

4-Bromophenylacetylene 1-Bromo-4-ethynylbenzene	Biochemical Assay Reagents	Others
1-Bromo-4-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Bromophenylacetylene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-115723

Antiallergic agent-1	Src	Inflammation/Immunology
Antiallergic agent-1, a Src-family kinase inhibitor, may serve as a new valuable lead compound for future antiallergic agent discovery. Antiallergic agent-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W588717

DBCO-Tetraacetyl mannosamine	Biochemical Assay Reagents	Others
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-149926

Cathepsin Inhibitor 3	Ser/Thr Protease	Others
Cathepsin Inhibitor 3 (Compound 53k) is a non-radioactive intermediate in compound [ ¹⁸F] 2k radioactive synthesis, which has selectivity for cathepsin S. Cathepsin Inhibitor 3 can undergo radioactive fluorination and can be used for fluorine-18 labeling research . Cathepsin Inhibitor 3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-155505

AHR agonist 4	Aryl Hydrocarbon Receptor	Inflammation/Immunology
AHR agonist 4 (compound 24e) is an agonist of Aryl hydrocarbon receptor (AHR), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion . AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132137

5-Propargylamino-3'-azidomethyl-dUTP	DNA/RNA Synthesis	Others
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-111302

Norgestrienone	Progesterone Receptor	Endocrinology
Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema .

HY-152726

TLR7 agonist 9	Toll-like Receptor (TLR) Nucleoside Antimetabolite/Analog	Infection Cancer
TLR7 agonist 9 (compound 10) is an aonist of TLR7. TLR7 agonist 9 can be used for research of cancer and infectious disease . TLR7 agonist 9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W250128

Dodecenylsuccinic anhydride (mixture of isomers) DDSA (mixture of isomers)	Biochemical Assay Reagents	Others
2-Dodecen-1-Ylsuccinic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Dodecenylsuccinic anhydride (mixture of isomers) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N7137

Norgestrel	Reactive Oxygen Species	Neurological Disease Cancer
Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120330

Nek2-IN-5	NEKs	Cancer
Nek2-IN-5 (compound 6) is a potent and irreversible Nek2 ((Never in mitosis gene a)-related kinase 2) inhibitior . Nek2-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Type

HY-D1506

Fl-DIBO

Dyes

Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1850

Sulfo-Cy7.5 azide

Fluorescent Dyes/Probes

Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-D1726

8RK59	Fluorescent Dyes/Probes
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC₅₀ close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .

HY-D1861

Sulfo-Cy3 hydrazide

Fluorescent Dyes/Probes

Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D1859

Sulfo-Cy7.5 alkyne

Fluorescent Dyes/Probes

Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

Cat. No.	Product Name	Type

HY-75970

Boc-Propargylamine N-Boc-Propargylamine	Biochemical Assay Reagents
N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W004104

4-Ethynylanisole	Biochemical Assay Reagents
4-Ethynylanisole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylanisole is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007423

3-Ethynylaniline	Biochemical Assay Reagents
3-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W004660

4-Ethynylaniline	Biochemical Assay Reagents
4-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007533

4-Ethynylbenzoic acid	Biochemical Assay Reagents
4-Ethynylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-34604

3-Ethynylpyridine	Biochemical Assay Reagents
3-Ethynylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylpyridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007542

4-Bromophenylacetylene 1-Bromo-4-ethynylbenzene	Biochemical Assay Reagents
1-Bromo-4-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Bromophenylacetylene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W588717

DBCO-Tetraacetyl mannosamine

Biochemical Assay Reagents

DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W145647

2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide

Biochemical Assay Reagents

2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl Azide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W127601

Lard oil

Co-solvents

Lard oil is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Lard oil is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132137

5-Propargylamino-3'-azidomethyl-dUTP

Gene Sequencing and Synthesis

5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W250128

Dodecenylsuccinic anhydride (mixture of isomers) DDSA (mixture of isomers)	Biochemical Assay Reagents
2-Dodecen-1-Ylsuccinic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Dodecenylsuccinic anhydride (mixture of isomers) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W145563

2-Azidoethyl β-D-glucopyranoside

Biochemical Assay Reagents

2-Azidoethyl β-D-Glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Azidoethyl β-D-glucopyranoside is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W002586

1-Chloro-2-ethynylbenzene	Biochemical Assay Reagents
1-Chloro-2-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 1-Chloro-2-ethynylbenzene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W001947

3-Butyn-1-ol	Biochemical Assay Reagents
3-Butyn-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Butyn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W012717

1-Ethyl-4-ethynylbenzene 4-Ethylphenylacetylene	Biochemical Assay Reagents
1-Ethyl-4-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 1-Ethyl-4-ethynylbenzene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W145547

2-Azidoethyl 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranoside

Biochemical Assay Reagents

2-Azidoethyl 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Azidoethyl 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranoside is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132138

5-Propargylamino-3'-azidomethyl-dCTP

Gene Sequencing and Synthesis

5-Propargylamino-3'-azidomethyl-dCTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 17. 5-Propargylamino-3'-azidomethyl-dCTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dCTP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W145549

2-Azidoethyl 2-Acetamido-2-deoxy-β-D-glucopyranoside

Carbohydrates

2-Azidoethyl 2-Acetamido-2-deoxy-β-D-glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Azidoethyl 2-Acetamido-2-deoxy-β-D-glucopyranoside is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132142

5-Propargylamino-dCTP

Gene Sequencing and Synthesis

5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis . 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W127719

Photobiotin acetate

Biochemical Assay Reagents

Photobiotin (acetate)It is a biological probe used to study biochemical processes such as protein interactions and enzymatic reactions. It is a molecule containing a photosensitive group, which can be combined with specific target molecules (such as proteins, nucleic acids, etc.) through photochemical cross-linking technology, so as to realize the labeling and detection of these molecules. During the photosensitive crosslinking process, Photobiotin (acetate)Can participate in the formation of covalent bonds and form stable compounds. In addition, the compound also has high biocompatibility and biological activity, so it is widely used in the field of biomedical research, such as enzymatic research, proteomics, western blotting and other aspects. Photobiotin (acetate) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W145531

Neu5GcAc[1Me,478Ac,9N3]-β-SPh

Biochemical Assay Reagents

Neu5GcAc[1Me,478Ac,9N3]-β-SPh is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Neu5GcAc[1Me,478Ac,9N3]-β-SPh is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Target	Research Area

HY-W006187

2-Amino-2-(p-tolyl)acetic acid	Glutaminase	Cancer
2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .

HY-13443B

Exendin-4-Lys-azide TFA	GCGR	Cardiovascular Disease Metabolic Disease Cancer
Exendin-4-Lys-azide TFA (Compound Ex40) is an azide derivative of Exendin-4-Lys-azide, Exendin-4, which can be used for coupling/click chemistry .

Cat. No.	Product Name		Classification

HY-151656

15-Azido-pentadecanoic acid 1 Publications Verification Azido Palmitic Acid		Azide Labeling and Fluorescence Imaging
15-Azido-pentadecanoic acid is a click chemistry reagent containing an azide group. Azido Palmitic Acid can be used to identify and characterize post-translationally palmitylated proteins with using a simple and robust two-step labeling and detection technique . 15-Azido-pentadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151719

Azidoacetic Acid 2-Azidoacetic acid		Azide PROTAC Synthesis
Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-130652

Pomalidomide 4'-PEG3-azide		Azide
Pomalidomide 4'-PEG3-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide-based cereblon ligand and a linker. Pomalidomide 4'-PEG3-azide can be used for the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3 is a highly efficient PARP1?degrader based on Rucaparib by using the PROTAC approach . Pomalidomide 4'-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W457949

Pomalidomide 4'-alkylC4-azide		Azide
Pomalidomide 4'-alkylC4-azide (Compound 2) is an azide compound containing a MIDI group and is one of the compounds used to construct a library of MIDI azide compounds. Pomalidomide 4'-alkylC4-azide can be used to develop research on PROTAC degraders .

HY-160077

Pomalidomide-CO-C5-azide		Azide
Pomalidomide-CO-C5-azide (Compound PA) is a ligand for E3 ligase bearing a bioorthogonal group azide. Pomalidomide-CO-C5-azide can be used to synthesize PROTACs with anticancer activity .

HY-161133

Lenalidomide 4'-PEG1-azide		Azide
Lenalidomide 4'-PEG1-azide (Compound 4g) is a lenalidomide-derived azide. Lenalidomide 4'-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide 4'-PEG1-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. .

HY-139341

Pomalidomide 4'-alkylC3-azide		Azide
Pomalidomide 4'-alkylC3-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC3-azide can be used in the synthesis of PROTAC .

HY-139343

Pomalidomide 4'-alkylC2-azide		Azide
Pomalidomide 4'-alkylC2-azide (compound 2a) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC2-azide can be used in the synthesis of PROTAC .

HY-156379

Biotin-PEG8-Alkyne		Alkynes Labeling and Fluorescence Imaging
Biotin-PEG8-Alkyne is an azide reactive compound .

HY-161131

Lenalidomide 4'-alkyl-C3-azide		Azide
Lenalidomide 4'-alkyl-C3-azide (compound 4a) is a click chemical modified Lenalidomide (HY-A0003) that can be used to synthesize PROTACs. Lenalidomide is an orally active immunomodulator and a ligand for the ubiquitin E3 ligase cereblon (CRBN). Lenalidomide 4'-alkyl-C3-azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition reactions (SPAAC) can also occur with molecules containing DBCO or BCN groups .

HY-W145647

2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide		Azide
2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl Azide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2,3,4,6-Tetra-O-acetyl-β-D-galactopyranosyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-139332

Pomalidomide 4'-PEG6-azide		Azide
Pomalidomide 4'-PEG6-azide (compound 33e) is the E3 ligase ligand-linker conjugate used in the recruitment of CRBN protein. Pomalidomide 4'-alkylC3-acid can be used to synthesize PROTACs .

HY-75970

Boc-Propargylamine N-Boc-Propargylamine		Alkynes
N-Boc-Propargylamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Boc-Propargylamine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W004104

4-Ethynylanisole		Alkynes
4-Ethynylanisole is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylanisole is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007423

3-Ethynylaniline		Alkynes
3-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145595

Ferroptosis inducer-1		Alkynes
Ferroptosis inducer-1 (compound BX-3a) is a Ferroptosis inducer with antitumor potential . Ferroptosis inducer-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W123012

APN-Azide 3-(4-Azidophenyl)propiolonitrile		Azide
APN-Azide (3-(4-Azidophenyl)propiolonitrile) is a codon-active compound that can achieve specific labeling of target molecules in biological systems through its unique chemical structure. APN-Azide can be used for bioimaging and the development of molecular probes to study biological processes within cells.

HY-W004660

4-Ethynylaniline		Alkynes
4-Ethynylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylaniline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W007533

4-Ethynylbenzoic acid		Alkynes
4-Ethynylbenzoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-34604

3-Ethynylpyridine		Alkynes
3-Ethynylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Ethynylpyridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-157573

N-Acetylmuramic acid-azide		Azide
N-Acetylmuramic acid-azide (Compound 2) is a derivative of N-acetylaminoacetic acid (NAM) in bacterial peptidoglycan. Incorporated into bacterial peptidoglycan during biosynthesis .

HY-146653

Glyoxalase I inhibitor 1		Alkynes
Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC₅₀ of 26 nM . Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1850

Sulfo-Cy7.5 azide		Azide
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W110146

(3aS,4S,6aR)-Biotin-PEG4-Alkyne		Labeling and Fluorescence Imaging
(3aS,4S,6aR)-Biotin-PEG4-Alkyne is an azide reactive compound .

HY-148908

TNF-α-IN-8		Azide
TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases . TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-115414

Bis-propargyl-PEG8		PROTAC Synthesis Alkynes
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-111642

3'-Azido-3'-deoxy-beta-L-uridine		Azide
3'-Azido-3'-deoxy-beta-L-uridine (Compound 25) is a nucleoside derivative. 3'-Azido-3'-deoxy-beta-L-uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-132137B

5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine		Azide
5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 5 in patent document WO2004018497A2. It contains an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC) .

HY-W007542

4-Bromophenylacetylene 1-Bromo-4-ethynylbenzene		Alkynes
1-Bromo-4-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 4-Bromophenylacetylene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W588717

DBCO-Tetraacetyl mannosamine		DBCO
DBCO-Tetraacetyl mannosamine is an organic compound commonly used for chemical alteration and modification in biological research. It can be used to modify glycoproteins, cell surface molecules, and other biomolecules, and is widely used in biomarking and purification techniques. In addition, this compound is used as a carrier for drugs in certain drug controlled release systems. DBCO-Tetraacetyl mannosamine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-149926

Cathepsin Inhibitor 3		Alkynes
Cathepsin Inhibitor 3 (Compound 53k) is a non-radioactive intermediate in compound [ ¹⁸F] 2k radioactive synthesis, which has selectivity for cathepsin S. Cathepsin Inhibitor 3 can undergo radioactive fluorination and can be used for fluorine-18 labeling research . Cathepsin Inhibitor 3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-155505

AHR agonist 4		Alkynes
AHR agonist 4 (compound 24e) is an agonist of Aryl hydrocarbon receptor (AHR), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion . AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132137

5-Propargylamino-3'-azidomethyl-dUTP		Azide
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-111302

Norgestrienone		Alkynes
Norgestrienone is a progestin receptor agonist. Norgestrienone is commonly used as a progesterone compound in birth control pills and can be combined with ethinylestradiol. Norgestrienone is a click chemical. It contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Azide groups. Norgestrienone can be used in the study of hereditary angioneurotic edema .

HY-W250128

Dodecenylsuccinic anhydride (mixture of isomers) DDSA (mixture of isomers)		Alkynes
2-Dodecen-1-Ylsuccinic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Dodecenylsuccinic anhydride (mixture of isomers) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N7137

Norgestrel		Alkynes
Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death . Norgestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120330

Nek2-IN-5		Alkynes
Nek2-IN-5 (compound 6) is a potent and irreversible Nek2 ((Never in mitosis gene a)-related kinase 2) inhibitior . Nek2-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-163213

Psoralen-triethylene glycol azide		Azide
Psoralen-triepthylene glycol azide is a compound used to probe the structure and conformation of RNA in living cells, using matching RNA crosslinking and deep sequencing or comradery methods .

HY-W145563

2-Azidoethyl β-D-glucopyranoside		Azide
2-Azidoethyl β-D-Glucopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Azidoethyl β-D-glucopyranoside is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-111641

3'-Azido-3'-deoxy-5-fluorocytidine		Azide
3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative. 3'-Azido-3'-deoxy-5-fluorocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-U00318

JAK-IN-11		Alkynes
JAK-IN-11 is a potent and selective JAK inhibitor extracted from patent WO2012122452A1, Compound II, has the potential for the skin disorders (such as cutaneous lupus) treatment . JAK-IN-11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W002586

1-Chloro-2-ethynylbenzene		Alkynes
1-Chloro-2-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 1-Chloro-2-ethynylbenzene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W001947

3-Butyn-1-ol		Alkynes
3-Butyn-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 3-Butyn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W012717

1-Ethyl-4-ethynylbenzene 4-Ethylphenylacetylene		Alkynes
1-Ethyl-4-ethynylbenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 1-Ethyl-4-ethynylbenzene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-Y1230

4-Pentynoic acid Propargylacetic acid		Alkynes
4-Pentynoic acid (Propargylacetic acid) is an intermediate to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers . 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-149058

Neuraminidase-IN-13		Azide
Neuraminidase-IN-13 (Compound 10) is a neuraminidase inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells . Neuraminidase-IN-13 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-147192

(S,R,S)-AHPC-O-PEG1-propargyl		Alkynes
(S,R,S)-AHPC-O-PEG1-propargyl (Compound 10b) is an E3 ligand for the synthesis of PROTAC . (S,R,S)-AHPC-O-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-155541

Antitumor agent-110		Alkynes
Antitumor agent-110 (compound 13) is an anticancer imidazotetrazine with good permeability properties. Antitumor agent-110 arrests cell cycel at G2/M phase, and induces apoptosis . Antitumor agent-110 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151744

N3-TFBA-O2Oc		Labeling and Fluorescence Imaging Azide
N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λ_max=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers . N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130390

Propargyl-PEG4-O-C1-NHS ester		Alkynes PROTAC Synthesis
Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-132137B

5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine		Nucleotides and their Analogs
5-Propargylamino-3'-azidomethyl-dUTP tristriethylamine is a nucleotide molecule that can be used in DNA synthesis and DNA sequencing. For detailed information, refer to compound 5 in patent document WO2004018497A2. It contains an azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also react with molecules containing DBCO or BCN groups through strain-promoted alkyne-azide cycloaddition (SPAAC) .

HY-132142

5-Propargylamino-dCTP		Nucleotides and their Analogs
5-Propargylamino-dCTP is a nucleoside molecule extracted from patent US9035035B2, compound dCTP-PA. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis . 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132137

5-Propargylamino-3'-azidomethyl-dUTP		Nucleotides and their Analogs
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-132138

5-Propargylamino-3'-azidomethyl-dCTP		Nucleotides and their Analogs
5-Propargylamino-3'-azidomethyl-dCTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 17. 5-Propargylamino-3'-azidomethyl-dCTP can be used in DNA synthesis and DNA sequencing . 5-Propargylamino-3'-azidomethyl-dCTP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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