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hydrogenation

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216

Inhibitors & Agonists

16

Screening Libraries

19

Fluorescent Dye

32

Biochemical Assay Reagents

6

Peptides

29

Natural
Products

15

Isotope-Labeled Compounds

2

Click Chemistry

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W015003

    N-Ethylcarbazole

    Others Others
    9-Ethylcarbazole (N-Ethylcarbazole) serves as a hydrogen storage material. The introduction of nitrogen (N) into 9-ethylcarbazole can reduce the endothermic nature of the reaction and decrease the dehydrogenation temperature, thereby facilitating the process of hydrogen storage and release .
    9-Ethylcarbazole
  • HY-121930

    Fluorescent Dye Inflammation/Immunology
    Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions .
    Coumarin 6H
  • HY-W015752

    Endogenous Metabolite Others
    5-Methoxyresorcinol is a member of the resorcinol family, which is phloroglucinol, in which phenol hydrogen is replaced by a methyl group. It has the function of a metabolite of brassica napus. 5-Methoxyresorcinol inhibits protein synthesis .
    5-Methoxyresorcinol
  • HY-15914

    DCHBS

    Fluorescent Dye Others
    DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .
    DHBS
  • HY-109582
    ADT-OH
    2 Publications Verification

    5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1

    Apoptosis Cancer
    ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases .
    ADT-OH
  • HY-127052

    Octadecanonitrile

    Others Others
    Stearonitrile is a stearic nitrile that can undergo hydrogenation reactions .
    Stearonitrile
  • HY-Y0701B

    Ammonium molybdate tetrahydrate, 81-83% MoO3 basis

    Biochemical Assay Reagents Others
    Ammonium molybdate tetrahydrate, for cell culture (Ammonium molybdate tetrahydrate, 81-83% MoO3 basis) is a reagent that can be used to determine extracellular hydrogen peroxide concentration .
    Ammonium molybdate tetrahydrate, for cell culture
  • HY-112652

    Others Neurological Disease
    ACS-67 is a hydrogen sulphide-releasing derivative of Latanoprost acid. ACS-67 has the potential for glaucoma research .
    ACS-67
  • HY-W455884

    Biochemical Assay Reagents Others
    3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase .
    3,5-Dichloro-2-hydroxybenzenesulfonic acid
  • HY-N3563

    Others Neurological Disease
    Celaphanol A is a diterpene that can be isolated from the root bark of Celastrus orbiculatus. Celaphanol A shows neuroprotective effect against a hydrogen peroxide-induced cytotoxicity in PC12 cells .
    Celaphanol A
  • HY-W402148

    ROS Kinase Others
    10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide .
    10-Methyl-9-(phenoxycarbonyl)acridinium (fluorosulfonate)
  • HY-132829

    GC4711

    Reactive Oxygen Species Cancer
    Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .
    Rucosopasem manganese
  • HY-W027631

    Others Infection
    cis-2-Butene-1,4-diol, an industrial product, can be used for the synthesis of antiviral product oxetanocin A. cis-2-Butene-1,4-diol is a probe for studying isomerization versus hydrogenation and hydrogenolysis reactions .
    cis-2-Butene-1,4-diol
  • HY-Y0337
    L-Cysteine
    4 Publications Verification

    Cysteine

    Endogenous Metabolite Metabolic Disease
    L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .
    L-Cysteine
  • HY-110128

    SF7-AM

    Fluorescent Dye Others
    Sulfidefluor 7-AM is a stable hydrogen sulphide (H2S) fluorescent probe . Sulfidefluor 7-AM is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Sulfidefluor 7-AM
  • HY-N10219

    Tyrosinase Fungal Infection
    Dihydroaltenuene B is a potent mushroom tyrosinase inhibitor with an IC50 of 38.33 µM. Dihydroaltenuene B shows the hydrogen bonding interactions between the 3-OH and 4’-OH and the His244, Met280 and Gly281 residues of tyrosinase .
    Dihydroaltenuene B
  • HY-P2742B

    Endogenous Metabolite Metabolic Disease
    Ascorbate oxidase, acremonium sp is a member of the multicopper blue oxidase family and primarily exists in plants as a free enzyme in the cytoplasm or bound to the cell wall. Ascorbate oxidase, acremonium sp has a high activity in catalyzing the oxidation of ascorbic acid to dehydroascorbic acid, regulating various cellular processes related to plant growth, protection, and development. Ascorbate oxidase, acremonium sp can be used to detect hydrogen peroxide .
    Ascorbate oxidase, acremonium sp
  • HY-Y0337R

    Endogenous Metabolite Metabolic Disease Cancer
    L-Cysteine (Standard) is the analytical standard of L-Cysteine. This product is intended for research and analytical applications. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .
    L-Cysteine (Standard)
  • HY-75070

    Biochemical Assay Reagents Others
    (+)-1-(1-Naphthyl)ethylamine ((+)-1-(1-NEA)) is a chiral modifier used to introduce enantioselectivity in catalytic hydrogenation reactions. 1-NEA can undergo H-D exchange with D2 in solution to form N?D bonds. That is, 1-NEA can complete Pt surface adsorption and protonation through amine N atoms, indicating that NEA molecules have the potential to impart enantioselectivity to Pt hydrogenation catalysts .
    (+)-1-(1-Naphthyl)ethylamine
  • HY-D1275

    Fluorescent Dye Others
    CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes .
    CAY10731
  • HY-129064

    SOD

    SOD Inflammation/Immunology Cancer
    Superoxide dismutase, Porcine erythrocytes (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase, Porcine erythrocytes is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications .
    Superoxide dismutase, Porcine erythrocytes
  • HY-109110

    GC-4419; M-40419

    Reactive Oxygen Species Inflammation/Immunology Cancer
    Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
    Avasopasem manganese
  • HY-136276

    Others Others
    DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation .
    DMNB-caged-Serine
  • HY-B1142
    Lipoamide
    5+ Cited Publications

    (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide

    NO Synthase Others
    Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
    Lipoamide
  • HY-Y1242

    Biochemical Assay Reagents Others
    Choline hydroxide is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .
    Choline hydroxide, 44 wt.% in water
  • HY-169228

    Btk Cancer
    WS-11 is a non-covalent reversible BTK inhibitor with IC50s of 3.9 nM and 2.2 nM for wild type, C481S mutation BTK, respectively. WS-11 can form strong π-π interaction with PHE540 and form p-π interaction with LYS430 within the active pocket, besides the strong hydrogen bonds .
    WS-11
  • HY-149234

    Monoamine Oxidase Neurological Disease
    MAO-B-IN-18 is a potent and selective MAO B inhibitor with IC50s of 52 nM and 14 μM for hMAO B and hMAO A, respectively. MAO-B-IN-18 enables promising cytoprotective effects against hydrogen peroxide insults in neuroblastoma and astrocytes cultures .
    MAO-B-IN-18
  • HY-156405

    Fat Mass and Obesity-associated Protein (FTO) Autophagy Metabolic Disease
    FTO-IN-10 (compound 7) is a potent human demethylase FTO (the fat mass and obesity-associated protein) inhibitor with an IC50 of 4.5 μM. FTO-IN-10 enters the FTO’s structural domain II binding pocket through hydrophobic and hydrogen bonding interactions. FTO-IN-10 induces DNA damage and autophagic cell death in A549 cells .
    FTO-IN-10
  • HY-150579

    Keap1-Nrf2 Inflammation/Immunology Cancer
    Keap1-Nrf2-IN-13 is a Keap1-Nrf2 protein–protein interaction (PPI) inhibitor with an IC50 value of 0.15 μM. Keap1-Nrf2-IN-13 has strong binding affinities to the Keap1 protein by forming hydrogen bond with the key polar residues (Asn414, Arg415, Arg483, Gln530). Keap1-Nrf2-IN-13 can be used in the research of oxidative stress-related and inflammatory diseases, including pulmonary fibrosis, chronic obstructive pulmonary disorder (COPD) and cancers .
    Keap1-Nrf2-IN-13
  • HY-126124
    AP39
    3 Publications Verification

    Others Cardiovascular Disease Neurological Disease
    AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research .
    AP39
  • HY-17459S

    (S)-(+)-Clopidogrel bisulfate-d3; (S)-(+)-Clopidogrel-d3 hydrogen sulfate

    P2Y Receptor Cytochrome P450 Cardiovascular Disease
    Clopidogrel-d3 (hydrogen sulfate) is the deuterium labeled Clopidogrel hydrogen sulfate[1]. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation.Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor[2][3][4][5][6].
    Clopidogrel-d3 hydrogen sulfate
  • HY-17459R

    (S)-(+)-Clopidogrel bisulfate (Standard); (S)-(+)-Clopidogrel hydrogen sulfate (Standard)

    Cytochrome P450 P2Y Receptor Cardiovascular Disease Cancer
    Clopidogrel (hydrogen sulfate) (Standard) is the analytical standard of Clopidogrel (hydrogen sulfate). This product is intended for research and analytical applications. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation .Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
    Clopidogrel hydrogen sulfate (Standard)
  • HY-17459
    Clopidogrel hydrogen sulfate
    20+ Cited Publications

    (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate

    Cytochrome P450 P2Y Receptor Cardiovascular Disease Cancer
    Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation .Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
    Clopidogrel hydrogen sulfate
  • HY-126474

    Reactive Oxygen Species Inflammation/Immunology
    MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals .
    MitoB bromide
  • HY-Y0037R

    Biochemical Assay Reagents Others
    Potassium hydrogen phthalate (Standard) is the analytical standard of Potassium hydrogen phthalate. This product is intended for research and analytical applications. Potassium 2-carboxybenzoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Potassium hydrogen phthalate (Standard)
  • HY-N0525
    Ethyl gallate
    1 Publications Verification

    Bacterial Metabolic Disease Cancer
    Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.
    Ethyl gallate
  • HY-W035155

    Others
    (1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate is a highly efficient catalyst with excellent hydrogenation activity. It can catalyze the reaction of hydrogen and organic substrates in various chemical reactions. This compound is often used to synthesize important chemical intermediates and compounds.
    (1,5-Cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate
  • HY-B1060

    Methylprednisolone hydrogen succinate sodium

    Glucocorticoid Receptor Inflammation/Immunology
    Methylprednisolone succinate (Methylprednisolone hydrogen succinate) sodium, a glucocorticoid, is a immunosuppressive agent with anti-inflammatory effects .
    Methylprednisolone succinate sodium
  • HY-W025371

    Others Others
    Dihydrosinapyl alcohol, a natural product, can be obtained from lignocellulose by hydrogenation and hydrogenolysis .
    Dihydrosinapyl alcohol
  • HY-123615

    Others Cardiovascular Disease Inflammation/Immunology
    SPD-2 is a photo-controlled hydrogen sulfide (H2S) donor that can generate hydrogen sulfide (H2S) upon UVA irradiation (325-385 nm). SPD-2 enables photo-controlled, site-specific H2S release in living cells .
    SPD-2
  • HY-Y1324

    Disodium hydrogen phosphate dodecahydrate; Disodium phosphate dodecahydrate

    Biochemical Assay Reagents Others
    Sodium phosphate dibasic dodecahydrate (Disodium hydrogen phosphate dodecahydrate), as a food additive, can be used to improve the texture of food .
    Sodium phosphate dibasic dodecahydrate
  • HY-P4280

    Reactive Oxygen Species Others
    Arg-Tyr is a dipeptide which has strong hydroxyl-radical and hydrogen-peroxide scavenging activity .
    Arg-Tyr
  • HY-D1896

    Fluorescent Dye Others
    Chloride Ionophore IV is a thiourea type hydrogen bonding-based receptor. Chloride Ionophore IV is a chloride ionophore .
    Chloride Ionophore IV
  • HY-W115775

    Biochemical Assay Reagents Others
    Potassium hydrogen oxalate is a kind of biological materials or organic compounds that are widely used in life science research .
    Potassium hydrogen oxalate
  • HY-165859

    Others Metabolic Disease
    2-Aminoethyl ((R)-2,3-bis(hexadecyloxy)propyl) hydrogen phosphate is an ester product.
    2-Aminoethyl ((R)-2,3-bis(hexadecyloxy)propyl) hydrogen phosphate
  • HY-W036734

    Biochemical Assay Reagents Others
    Tetrabutylammonium (hydrogen difluoride) is a quaternary ammonium salt containing fluoride ions. It is a highly active and effective reagent, often used in organic synthesis reactions, especially for the modification of organic molecules with fluorine atoms. Tetrabutylammonium (hydrogen difluoride) is also used as a catalyst for various chemical reactions such as esterification and transesterification. Additionally, it is used in the production of specialty chemicals such as surfactants and detergents.
    Tetrabutylammonium (hydrogen difluoride)
  • HY-Y0708

    Calcium phosphate dihydrate

    Biochemical Assay Reagents Others
    Calcium hydrogen phosphate dihydrate, also known as CHPD or DCPD.Calcium hydrogen phosphate dihydrate can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Calcium hydrogen phosphate dihydrate
  • HY-D0391

    Fluorescent Dye
    C.I Acid orange 8 is an acidic orange dye that photochemically decolorizes during a UV/hydrogen peroxide process.
    C.I Acid orange 8
  • HY-W088069

    Biochemical Assay Reagents Others
    Dipotassium hydrogen phosphate trihydrate, which is commonly used as a buffer and source of phosphorus and potassium in various applications, such as fertilizers, food processing, and pharmaceuticals, in biochemistry and molecular biology, Dipotassium hydrogen phosphate trihydrate is used in the preparation of cell culture media And reagent buffer system, in addition, it has been used in analytical chemistry as a reagent for the determination of calcium and magnesium ions in water samples.
    Dipotassium hydrogen phosphate trihydrate
  • HY-114541

    Fluorescent Dye Others
    Coumarin-7-pinacolboronate is a fluorescent probe. Taking hydrogen peroxide for instance, Coumarin-7-pinacolboronate and HOO- undergo a nucleophilic reaction to produce INT1. The chemical reaction mechanisms are nearly identical for the reactions of Coumarin-7-pinacolboronate with hydrogen peroxide, hypochlorous acid, peroxynitrite, and tyrosine hydroperoxide, respectively .
    Coumarin-7-pinacolboronate

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