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95

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2

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8

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6

Biochemical Assay Reagents

10

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3

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8

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12

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1

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4

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126561
    Green CMFDA
    2 Publications Verification

    CMFDA

    Fluorescent Dye Others
    Green CMFDA is a cell-permeable fluorescent probe with Em of 514 nm and Ex of 485 nm and can be used as a cell tracer. Green CMFDA can be cleaved by non-specific esterases common in living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope .
    Green CMFDA
  • HY-P2853

    Endogenous Metabolite Infection Inflammation/Immunology Cancer
    Hemocyanin is a large copper-containing respiratory protein. Hemocyanin is an important non-specific innate immune defense molecule with phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities .
    Hemocyanin
  • HY-19695
    (-)-p-Bromotetramisole oxalate
    1 Publications Verification

    L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate

    Phosphatase Cancer
    (-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
    (-)-p-Bromotetramisole oxalate
  • HY-P2495A

    Biochemical Assay Reagents Inflammation/Immunology
    OVA (241-270) TFA, a non-specific cytotoxic T lymphocyte (CTL) peptide, is a fragmented peptide of OVA (ovalbumin) antigen .
    OVA (241-270) TFA
  • HY-E70314

    non-specific Endonuclease

    Endogenous Metabolite Others
    Nuclease SM is a non-specific endonuclease found mainly in Salmonella and is a basic protein. Nuclease SM is thermolabile and remains active for ~24 h at 25°C .
    Nuclease SM
  • HY-148159

    Monoamine Oxidase Neurological Disease
    Safrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression .
    Safrazine
  • HY-113821

    Phosphatase Others
    1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor. 1-Naphthyl phosphate potassium salt decreases the splice-correcting effect .
    1-Naphthyl phosphate potassium salt
  • HY-P2495

    Biochemical Assay Reagents Cancer
    OVA (241-270), a non-specific cytotoxic T lymphocyte (CTL) peptide, is a fragmented peptide of OVA (ovalbumin) antigen .
    OVA (241-270)
  • HY-139852

    Phosphatase Cancer
    PLAP-IN-1 is a potent (IC50 = 32 nM) and selective PLAP inhibitor, with no detectable inhibition of tissue non-specific alkaline phosphatase (TNAP) activity.
    PLAP-IN-1
  • HY-148796

    GE3126

    Fluorescent Dye Others
    Rizedisben (GE3126) is a fluorophore that can be used in fluorescence image-guided surgery. Rizedisben reduces non-specific adipose tissue fluorescence intensity and enhances nerve visibility .
    Rizedisben
  • HY-135530

    Amylases Metabolic Disease
    Chinese gallotannin is a non-specific promiscuous α-amylase inhibitor with a Ki of 0.82 μg/mL for human salivary α-amylase. Chinese gallotannin can be used for the research of diabetes .
    Chinese gallotannin
  • HY-155471

    Biochemical Assay Reagents Others
    IMP 245 is a symmetric di-HSG bivalent hapten. IMP 245 has low toxicity, high affinity binding to available antibodies and absence of cross reactivity or non-specific binding with body components .
    IMP 245
  • HY-B1056

    Propazol; 2-Benzimidazolepropionic acid

    Bacterial Parasite Antibiotic Carbonic Anhydrase Infection Cancer
    Procodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity .
    Procodazole
  • HY-101370

    P2X Receptor Metabolic Disease
    2-Methylthio-ATP tetrasodium is a non-specific P2-receptor agonist. 2-Methylthio-ATP tetrasodium causes noncompetitive inhibition of ADP-induced human platelet aggregation .
    2-Methylthio-ATP tetrasodium
  • HY-156262

    Biochemical Assay Reagents Others
    DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity .
    DEPC-Treated Water
  • HY-108909

    Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Chymopapain is a non-specific proteo-glycanase derived from the papaya plant. Chymopapain directly into the intervertebral disc caused disc narrowing due to dissolution of the extruded material. Chymopapain has the potential for the research of herniated lumbar discs .
    Chymopapain
  • HY-12489

    Acid Red 112

    Fluorescent Dye Others
    Ponceau S (Acid Red 112) is a non-specific protein dye commonly used as a stain for Western blot. Ponceau S is used in an acidic aqueous solution that is compatible with antibody-antigen binding and dyes the proteins on the membrane red .
    Ponceau S
  • HY-135146
    GSK-3484862
    10+ Cited Publications

    DNA Methyltransferase Cancer
    GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity .
    GSK-3484862
  • HY-P0262A

    Neuropeptide Y Receptor Neurological Disease Metabolic Disease
    Galantide TFA is a reversible and non-specific galanin (GAL) receptor antagonist. Galantide TFA dose-dependently shows antagonism to galanin-induced K + conductance with an IC50 value of 4 nM. Galantide TFA can be used for the research of neurological disease and hormone metabolism research .
    Galantide TFA
  • HY-121964

    iGluR Neurological Disease
    Cis-piperidine-2,3-dicarboxylic acid is a non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Cis-piperidine-2,3-dicarboxylic acid can be used in blocking general excitatory synaptic transmissions .
    cis-Piperidine-2,3-dicarboxylic acid
  • HY-169871

    iGluR Neurological Disease
    Argiotoxin 636 is a toxin and the non-specific, non-competitive, and potent ionotropic glutamate receptor (iGluR) antagonist. Argiotoxin 636 blocks excitatory synaptic transmission in neurons and has paralysis and muscle relaxation effects. Argiotoxin 636 can be used in the study of nervous system diseases .
    Argiotoxin 636
  • HY-124814

    Bacterial Infection
    C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis, limited non-specific toxicity against mammalian cells, an IC90 of 16 μM against M. tuberculosis, and efficacy against M. tuberculosis growing in macrophages .
    C215
  • HY-D0047
    5-CFDA
    3 Publications Verification

    5-Carboxyfluorescein diacetate

    Fluorescent Dye Others
    5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
    5-CFDA
  • HY-D0721

    6-Carboxyfluorescein diacetate

    Fluorescent Dye Others
    6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
    6-CFDA
  • HY-D0722
    5(6)-CFDA
    5+ Cited Publications

    5-(6)-Carboxyfluorescein diacetate; CFDA

    Fluorescent Dye Others
    5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .
    5(6)-CFDA
  • HY-N7648

    Atherospermine

    Parasite Infection
    Atherosperminine(Atherospermine)is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC50 of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis .
    Atherosperminine
  • HY-126327

    Histone Methyltransferase Cancer
    UNC4976 is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
    UNC4976
  • HY-D0846

    Biochemical Assay Reagents Neurological Disease
    Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling .
    Diethyl pyrocarbonate
  • HY-A0082

    Difenidol hydrochloride

    mAChR Sodium Channel Neurological Disease
    Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na +, K +, and Ca 2+) in neuronal cells. Diphenidol hydrochloride can be used in the study of antivertigo and antinausea .
    Diphenidol hydrochloride
  • HY-A0270

    mAChR Sodium Channel Neurological Disease
    Diphenidol is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol is also a potent non-specific blocker of voltage-gated ion channels (Na +, K +, and Ca 2+) in neuronal cells. Diphenidol can be used in the study of antivertigo and antinausea .
    Diphenidol
  • HY-126327A

    Histone Methyltransferase Cancer
    UNC4976 TFA is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 TFA simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA .
    UNC4976 TFA
  • HY-115749

    6′-Methoxyluciferin

    Fluorescent Dye Others
    D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 µM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .
    D-Luciferin 6′-methyl ether
  • HY-115749A

    (Rac)-6′-Methoxyluciferin sodium

    Drug Derivative Others
    D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site .
    (Rac)-Luciferin 6′-methyl ether sodium
  • HY-D1421
    PKH 67
    3 Publications Verification

    Fluorescent Dye Others
    PKH67 is a fluorescent cell binding dye with green fluorescence. PKH67 can stain the cell membrane and the Ex/Em is 490/502 nm. PKH67 is often used in combination with the non-specific red fluorescent dye PKH26 (Ex/Em=551/567 nm) to label cells, detect cell proliferation in vitro, and trace cells in vitro and in vivo .
    PKH 67
  • HY-135146A

    DNA Methyltransferase Cancer
    (Rac)-GSK-3484862 is the isomer of GSK-3484862 (HY-135146), and can be used as an experimental control. GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity .
    (Rac)-GSK-3484862
  • HY-100367

    Quinone Reductase Cancer
    ES 936 is a potent and specific NQO1 inhibitor, effective at concentrations over 1000 times lower than the non-specific inhibitor Dicoumarol (HY-N0645). NQO1 is generally considered a detoxification enzyme, capable of directly reducing quinones to hydroquinones, which in turn prevents the formation of reactive oxygen species arising from redox cycling. ES 936 can be utilized in cancer research .
    ES 936
  • HY-A0082R

    mAChR Sodium Channel Neurological Disease
    Diphenidol (hydrochloride) (Standard) is the analytical standard of Diphenidol (hydrochloride). This product is intended for research and analytical applications. Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. Diphenidol hydrochloride can be used in the study of antivertigo and antinausea [4] .
    Diphenidol (hydrochloride) (Standard)
  • HY-P0262

    Neuropeptide Y Receptor Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
    Galantide, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40 nM) .
    Galantide
  • HY-108760

    Gd-DOTA; Magnescope; P-449

    Biochemical Assay Reagents Cardiovascular Disease Others Neurological Disease
    Gadoterate meglumine (Gd-DOTA) is a non-specific paramagnetic gadolinium complex used as a contrast enhancer in magnetic resonance imaging (MRI). Gadoterate meglumine, as a contrast agent in MRI, is able to shorten the longitudinal relaxation time (T1) of tissue, resulting in a brighter signal in MRI images. Gadoterate meglumine can be used for the study of the central nervous system (such as the brain and spinal cord), abdominal, pelvic organs, breast, bone and joint imaging, angiography, and cardiac electrophysiology .
    Gadoterate meglumine
  • HY-164360

    Integrin Inflammation/Immunology Cancer
    αVβ8-IN-1 is a αVβ8 integrin inhibitor. αVβ8-IN-1 has been shown to inhibit the growth of tumors such as EMT6, CT26, KPC, and TKCC-10. αVβ8-IN-1 can be used in research related to idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP), and tumors .
    αVβ8-IN-1
  • HY-115576
    P62-mediated mitophagy inducer
    4 Publications Verification

    PMI

    p62 Mitophagy Autophagy Neurological Disease Cancer
    P62-mediated mitophagy inducer (PMI) is a P62-mediated mitophagy activator. P62-mediated mitophagy inducer activates mitochondrial autophagy without recruitment of Parkin or collapse of the mitochondrial membrane potential and remains active in cells lacking a fully functional PINK1/Parkin pathway. P62-mediated mitophagy inducer serves as a pharmacological tool to study the molecular mechanisms of mitosis, avoiding toxicity and some of the non-specific effects associated with the sudden dissipation of mitochondria lacking membrane potential .
    P62-mediated mitophagy inducer
  • HY-103389
    1-Aminobenzotriazole
    5 Publications Verification

    ABT; 3-Aminobenzotriazole

    Cytochrome P450 Cancer
    1-Aminobenzotriazole is a nonspecific and irreversible inhibitor of cytochrome P450 (P450).
    1-Aminobenzotriazole
  • HY-145127

    C3-CA-DTZ

    Fluorescent Dye Neurological Disease
    ETZ (C3-CA-DTZ) is a promising luciferase substrate (prosubstrate) activatable in vivo by nonspecific esterase to enhance the brain delivery of the luciferin .
    ETZ
  • HY-78144

    IAP Inflammation/Immunology
    4-Methylsalicylic acid is a salicylic acid. 4-Methylsalicylic acid derivative is a selective tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibitor .
    4-Methylsalicylic acid
  • HY-101959A

    Ser/Thr Protease Cancer
    Tyrphostin 47 is a nonspecific inhibitor of WNK1. Tyrphostin 47 is a protein tyrosine kinase inhibitor. Tyrphostin 47 inhibits smooth-muscle cell proliferation
    Tyrphostin 47
  • HY-121966

    Riparin III

    Others Cancer
    Riparin is a nonspecific smooth muscle relaxant. Riparin inhibits CaCl2-induced contractions in a reversible and non-competitive manner and can be used in spasmolytic studies .
    Riparin
  • HY-122409

    Others Others
    Cularine is a compound that relaxes guinea pig tracheal and human bronchial smooth muscle, inhibits contraction induced by a variety of contractile agents, and has nonspecific antispasmodic activity, and its activity is structure-related.
    Cularine
  • HY-115431

    Aminopeptidase Neurological Disease
    Antho-rwamide I is a neuropeptide that can be isolated from the sea anemone Anthopleura elegantissima. Antho-rwamide I is resistant to nonspecific aminopeptidases, which increases the stability of the peptide after neuronal release .
    Antho-rwamide I
  • HY-126707

    Drug Metabolite Others
    Aldoifosfamide, a compound used to quantify 4-hydroxyifosfamide, was measured in plasma by a specific method with results that were not significantly different from another method, suggesting that existing nonspecific methods are acceptable in specific circumstances.
    Aldoifosfamide
  • HY-131160

    Serratia marcescens nuclease

    Biochemical Assay Reagents Inflammation/Immunology
    Serratia marcescens nuclease (EC 3.1.30.2) is a nonspecific nuclease. Serratia marcescens nuclease has broad utility due to its potent digestive activity toward both DNA and RNA .
    Nuclease, Serratia marcescens

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