2. Gene
  3. Pgp - phosphoglycolate phosphatase Gene

Pgp - phosphoglycolate phosphatase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AUM; G3PP; RGD1307773

Gene ID: 287115 | Gene type: protein coding

About Pgp

Summary

Enables glycerol-3-phosphatase activity. Involved in glycerol biosynthetic process; glycerophospholipid metabolic process; and negative regulation of gluconeogenesis. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human PGP (phosphoglycolate Phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Pgp Products(1)

mRNA Protein Name
NM_001169152.1 NP_001162623.1 glycerol-3-phosphate phosphatase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables glycerol-3-phosphatase activity IMP
IMP: Inferred from mutant phenotype
26755581 RGD
Biological Process GO Annotation Evidence Reference Source
involved in glycerol biosynthetic process IDA
IDA: Inferred from direct assay
26755581 RGD
involved in glycerophospholipid metabolic process IMP
IMP: Inferred from mutant phenotype
26755581 RGD
involved in negative regulation of gluconeogenesis IMP
IMP: Inferred from mutant phenotype
26755581 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate phosphatase

aspartate-based ubiquitous Mg(2+)-dependent phosphatase

Related Agents

Approval
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14275 Verapamil 99.96% Yes
HY-10440 Vismodegib 99.97% Yes
HY-A0064 Verapamil hydrochloride 99.98% Yes
HY-B0777 Moxidectin Inhibitor 99.32% Yes
HY-17367 Atazanavir 99.86% Yes
HY-17367A Atazanavir sulfate 99.94% Yes
HY-145574 Iruplinalkib Inhibitor 99.62% Unkown
HY-16397 Phenformin 99.72% Unkown
HY-N7120 Penicillin G procaine hydrate Inhibitor 99.52% Unkown
HY-B0501 Danofloxacin mesylate Inhibitor 99.87% Unkown
HY-A0064R Verapamil (hydrochloride) (Standard) / Unkown
HY-B0777R Moxidectin (Standard) Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Phase
HY-10550 Tariquidar Inhibitor 99.45% Phase 3
HY-50671 Zosuquidar trihydrochloride Inhibitor 99.79% Phase 3
HY-15255 Zosuquidar Inhibitor 99.90% Phase 3
HY-10550A Tariquidar methanesulfonate, hydrate Inhibitor 98.52% Phase 3
HY-17013A Dofequidar fumarate Inhibitor ≥98.0% Phase 3
HY-110377 Tariquidar dihydrochloride Inhibitor / Phase 3
HY-19642A Glesatinib hydrochloride Inhibitor 98.01% Phase 2
HY-106004 Zamicastat Inhibitor 99.93% Phase 2
HY-14942 Berubicin Inhibitor 87.76% Phase 2
HY-132189 Laniquidar Inhibitor / Phase 2
HY-19642 Glesatinib Inhibitor / Phase 2
HY-16773 Vedroprevir Inhibitor / Phase 2
HY-50879 Elacridar Inhibitor 99.94% Phase 1
HY-108286 Talinolol Antagonist 99.64% Phase 1
HY-17013D Dofequidar sesquifumarate Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (119)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10010 Ko 143 Inhibitor 99.97% Unkown
HY-13925 PD0166285 99.46% Unkown
HY-50880 Elacridar hydrochloride Inhibitor 99.93% Unkown
HY-N6684 Deoxynivalenol 99.39% Unkown
HY-108694 γ-Tocotrienol Inhibitor 99.73% Unkown
HY-107643 Reversan Inhibitor 99.90% Unkown
HY-N0217 Benzoylaconine 99.92% Unkown
HY-N3584 Paris saponin VII 99.96% Unkown
HY-W009141 1-Monopalmitin Inhibitor 99.42% Unkown
HY-N1941 Isosinensetin Inhibitor 99.90% Unkown
HY-N2453 Convallatoxin 98.66% Unkown
HY-100750 Norverapamil hydrochloride Inhibitor 99.80% Unkown
HY-161246 uPSEM792 Agonist 99.92% Unkown
HY-N6932 Voacamine 99.64% Unkown
HY-N2103 Tenacissoside G 99.64% Unkown
HY-113805 MC70 Inhibitor 99.50% Unkown
HY-162753 ZW-1226 Inhibitor 98.13% Unkown
HY-A0064S Verapamil-d3 hydrochloride 99.57% Unkown
HY-N1457 Chrysosplenetin 99.68% Unkown
HY-119823 PGP-4008 Inhibitor 99.69% Unkown
HY-126940 Furanodiene 99.65% Unkown
HY-W001601 Budipine Antagonist 99.41% Unkown
HY-19626 NSC23925 Inhibitor 99.43% Unkown
HY-101791 P-gp inhibitor 1 Inhibitor 98.79% Unkown
HY-119101 AZD-5672 95.74% Unkown
HY-132866 YS-370 Inhibitor 98.50% Unkown
HY-N2416 Taccalonolide A 99.29% Unkown
HY-N4108 Hypophyllanthin Inhibitor 98.84% Unkown
HY-N6748 Roquefortine C 98.42% Unkown
HY-17013 Dofequidar Inhibitor 98.17% Unkown
HY-143792 HTT-D3 Inhibitor / Unkown
HY-N3028 Taccalonolide B Inhibitor 99.46% Unkown
HY-B0777S Moxidectin-d3 Inhibitor / Unkown
HY-162373 α-Amylase/α-Glucosidase-IN-10 Inhibitor / Unkown
HY-112912 P-gp modulator 1 / Unkown
HY-130244 BACE1-IN-5 Inhibitor / Unkown
HY-10550B Tariquidar dimesylate Inhibitor / Unkown
HY-128685 FD 12-9 Inhibitor / Unkown
HY-146096 RMS3 / Unkown
HY-146097 RMS5 / Unkown
HY-149053 OY-101 Inhibitor / Unkown
HY-17367S2 Atazanavir-d9 / Unkown
HY-17367S3 Atazanavir-d5 / Unkown
HY-106753 Tolnapersine / Unkown
HY-108286S (Rac)-Talinolol-d5 Antagonist / Unkown
HY-116976 NSC-57969 / Unkown
HY-121247 Bromotetrandrine Inhibitor / Unkown
HY-135328 Norverapamil Inhibitor / Unkown
HY-135328AS Norverapamil-d7 hydrochloride Antagonist 98.77% Unkown
HY-135328S Norverapamil-d7 Inhibitor / Unkown
HY-13925A PD0166285 dihydrochloride / Unkown
HY-14275S1 Verapamil-d7 / Unkown
HY-144366 P-gp inhibitor 3 Inhibitor / Unkown
HY-144393 P-gp/BCRP-IN-1 Inhibitor / Unkown
HY-146117 P-gp modulator 2 Modulator / Unkown
HY-146118 P-gp modulator 3 Modulator / Unkown
HY-146391 P-gp inhibitor 4 Modulator / Unkown
HY-147758 BACE1/2-IN-1 Inhibitor / Unkown
HY-149053B (R)-OY-101 / Unkown
HY-149240 Anticancer agent 108 Inhibitor / Unkown
HY-149277 FM04 Inhibitor / Unkown
HY-149360 P-gb-IN-1 Inhibitor / Unkown
HY-149813 P-gp inhibitor 14 Inhibitor / Unkown
HY-149981 P-gp inhibitor 13 Inhibitor / Unkown
HY-150565 P-gp inhibitor 5 Inhibitor / Unkown
HY-152079 CYP1B1-IN-3 Inhibitor / Unkown
HY-155032 P-gp inhibitor 15 Inhibitor / Unkown
HY-155391 hCA/Wnt/β-catenin-IN-1 Inhibitor 99.96% Unkown
HY-157330 P-gp inhibitor 16 / Unkown
HY-157483 P-gp inhibitor 18 Inhibitor / Unkown
HY-157484 P-gp inhibitor 19 Inhibitor / Unkown
HY-157876 Anticancer agent 191 Inhibitor / Unkown
HY-158236 ORL1 antagonist 2 Antagonist / Unkown
HY-158435 P-gp inhibitor 23 Inhibitor / Unkown
HY-159085 P-gp inhibitor 24 Inhibitor / Unkown
HY-159935 Top1-IN-2 Inhibitor / Unkown
HY-161260 P-gp inhibitor 20 Inhibitor / Unkown
HY-161645 P-gp modulator-4 Modulator / Unkown
HY-161776 P-gp/CDK2-IN-1 Inhibitor / Unkown
HY-162040 P-gp inhibitor 17 Inhibitor / Unkown
HY-162369 PID-9 Inhibitor / Unkown
HY-162396 P-gp inhibitor 21 Inhibitor / Unkown
HY-162447 P-gp inhibitor 22 / Unkown
HY-162822 P-gp modulator-5 Modulator / Unkown
HY-163204 RhQ-DMB Inhibitor / Unkown
HY-168008 P-gp inhibitor 25 Inhibitor / Unkown
HY-168186 P-gp inhibitor 26 Inhibitor / Unkown
HY-168711 P-gp inhibitor 27 Inhibitor / Unkown
HY-168953 Lysosomal P-gp targeted agent 1 / Unkown
HY-172365 P7–2302 Inhibitor / Unkown
HY-173182 Antitumor agent-200 Inhibitor / Unkown
HY-173222 P-gp inhibitor 28 Inhibitor / Unkown
HY-17367S4 Atazanavir-d6 99.28% Unkown
HY-A0064S1 Verapamil-d6 hydrochloride / Unkown
HY-N10563 Coleon-U-quinone Inhibitor / Unkown
HY-N10564 8α,9α-Epoxycoleon-U-quinone Modulator / Unkown
HY-N144114 P-gp inhibitor 2 Inhibitor / Unkown
HY-P10856 CPI1 Inhibitor / Unkown
HY-RS10394 PGP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W140488 1,2-Didecanoyl-sn-glycero-3-phosphoethanolamine / Unkown
HY-W286423 L-Pyroglutamic acid 7-amido-4-methylcoumarin Substrate / Unkown
HY-W700684 N-Didesmethyl Loperamide / Unkown
HY-107197 8-Prenylchrysin Inhibitor / Unkown
HY-123934 VU6007477 Modulator / Unkown
HY-129698 MS-073 Inhibitor / Unkown
HY-13646B Encequidar hydrochloride Inhibitor / Unkown
HY-141425 NSC73306 / Unkown
HY-14275S Verapamil-d3 / Unkown
HY-14275S2 Verapamil-d6 / Unkown
HY-169782 CJZ3 Inhibitor / Unkown
HY-17367S5 Atazanavir-d24 / Unkown
HY-N13157 11α-O-Benzoyl-12β-O-acetyltenacigenin B Inhibitor / Unkown
HY-N7305 Jatrophane 5 Inhibitor / Unkown
HY-N7332 Pepluanin A Inhibitor / Unkown
HY-W699430 Norverapamil-d6 hydrochloride Inhibitor / Unkown
HY-W705354 Vismodegib-d4 / Unkown
HY-W716916 Vismodegib-d7 / Unkown
HY-W854295 Phosphatidylinositol-1,2-dioctanoyl sodium Inhibitor / Unkown
HY-U00247 MCI826 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgp NCBI NCBI:283871
Macaca fascicularis Pgp NCBI NCBI:102115347
Mus musculus Pgp NCBI NCBI:67078