2. Gene
  3. STK16 - serine/threonine kinase 16 Gene

STK16 - serine/threonine kinase 16 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PSK; KRCT; MPSK; TSF1; hPSK; PKL12

Gene ID: 8576 | Gene type: protein coding

About STK16

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:219,245,479-219,250,337 (from NCBI)

This gene has 13 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 7.6), brain (RPKM 6.9) and 25 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Involved in protein autophosphorylation. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

STK16 Products(4)

mRNA Protein Name
NM_001008910.4 NP_001008910.1 serine/threonine-protein kinase 16 isoform 1
NM_001330213.2 NP_001317142.1 serine/threonine-protein kinase 16 isoform 1
NM_001330214.1 NP_001317143.1 serine/threonine-protein kinase 16 isoform 2
NM_001330215.2 NP_001317144.1 serine/threonine-protein kinase 16 isoform 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence Reference Source
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
18184589 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STK16 Protein Structure

Pkinase

Pkinase: Protein kinase domain (22 - 287)

  • 0
  • 100
  • 200
  • 305 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase 16

TGF-beta-stimulated factor 1

Recombinant STK16 Proteins

Cat. No. Product Name Accession Purity
HY-P76097 STK16 Protein, Human (His) O75716 (M1-I305) ≥95%

Related Diseases

Diseases Alias
Diffuse Mesangial Sclerosis

Familial Mesangial Sclerosis

Mesangial Sclerosis, Diffuse

Dms

Diffuse Isolated Mesangial Sclerosis

Isolated Diffuse Mesangial Sclerosis

Nephrotic Syndrome, Early Onset With Diffuse Mesangial Sclerosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19353 SR7826 Inhibitor 99.30% Unkown
HY-101270 STK16-IN-1 Inhibitor 99.95% Unkown
HY-RS13923 STK16 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus STK16 VGNC VGNC:65776
Mus musculus STK16 MGD MGI:1313271
Rattus norvegicus STK16 RGD RGD:629474
Canis familiaris STK16 VGNC VGNC:46906
Bos taurus STK16 VGNC VGNC:35387
Macaca mulatta STK16 VGNC VGNC:77912
Others STK16 NCBI