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MRSA.

" in MedChemExpress (MCE) Product Catalog:

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197

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-171233

MRSA antibiotic 2	Bacterial	Infection
MRSA antibiotic 2 (compound 2) shows MIC of 2 μg/mL for S. aureus (MRSA). MRSA antibiotic 2 selectively target Gram-positive bacteria over Gram-negative bacteria and human cells .

HY-168705

*Anti-MRSA* agent 20**	Bacterial	Infection
Anti-MRSA agent 20 (Compound a4) is an anti-microbial agent (MIC: < 0.03125 μg/mL) against *MRSA). Anti-MRSA* agent 20 binds to the ribosomal peptidyl transferase center and inhibits bacterial survival by inhibiting MRSA toxin synthesis and bacterial division. Anti-MRSA agent 20 significantly reduces the MRSA load in the lungs and attenuates lung injury in the MRSA-infected mice (ED₅₀ = 6.48 mg/kg) .

HY-161827

*Anti-MRSA* agent 14**	Bacterial	Infection
Anti-MRSA agent 14 (Compound C17) has antibacterial agent against MRSA and MRSA-infected skin murine model. Anti-MRSA agent 14 is more potential than Norfloxacin (HY-B0132) against MRSA. Anti-MRSA agent 14 disrupts cell membrane and restrains metabolism. Anti-MRSA agent 14 shows antibacterial effects against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA with MIC values of 1, 2, 2, 1 μM respectively .

HY-144278

*Anti-MRSA* agent 1**	Bacterial	Infection Inflammation/Immunology
Anti-MRSA agent 1 (Compound 13d) is a wonderful *MRSA* (MIC = 0.5 μg/mL) inhibitor. Anti-MRSA agent 1 (Compound 13d) could effectually relieve the development of MRSA resistance .

HY-163073

*Anti-MRSA* agent 9**	Bacterial	Infection
Anti-MRSA agent 9 (compound 39) shows antibacterial effects against clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) with MIC values of 1 μg/ml. Anti-MRSA agent 9 also shows *anti-MRSA* efficacy in vivo .

HY-163906

*Anti-MRSA* agent 16**	Bacterial	Infection
Anti-MRSA agent 16 (Compound 4) is an inhibitor of methicillin-resistant Staphylococcus aureus (MRSA). Anti-MRSA agent 16 is effective in combination with oxacillin or meropenem in infected mice .

HY-156289

*Anti-MRSA* agent 8**	Bacterial	Infection
Anti-MRSA agent 8 (Compound 7g) is a DAPG derivative with strong antibacterial activity. Anti-MRSA agent 8 assertes its activity by targeting bacterial cell membranes. Anti-MRSA agent 8 can be used for the research of methicillin-resistant Staphylococcus aureus (MRSA) .

HY-161893

*Anti-MRSA* agent 15**	Bacterial	Infection
Anti-MRSA agent 15 (Compound 9o10) exhibits antibacterial activity, that inhibits methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 0.0625 μg/mL. Anti-MRSA agent 15 exhibits low hemolysis and low cytotoxicity. Anti-MRSA agent 15 exhibits anti-infective in mice .

HY-168873

*Anti-MRSA* agent 23**	Bacterial	Infection
Anti-MRSA agent 23 (compound 11) is a potent anti-methicillin-resistant Staphylococcus aureus agent. Anti-MRSA agent 23 shows antibacterial and antibiofilm activities. Anti-MRSA agent 23 accelerates the reconstruction and healing of MRSA-infected cutaneous wounds by decreasing bacterial loads, attenuating inflammation, and promoting angiogenesis .

HY-170802

*Anti-MRSA* agent 22**	Bacterial	Infection
Anti-MRSA agent 22 (Compound 5a) is a potent antibacterial agent against *MRSA* with a MIC value of 6 µg/mL. Anti-MRSA agent 22 exhibits high binding affinity (−11.19) to FabI .

HY-161823

*Anti-MRSA* agent 13**	Bacterial	Infection
Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated *MRSA* strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to *MRSA* death through multi-target synergies .

HY-169416

*Anti-MRSA* agent 21**	Bacterial Reactive Oxygen Species	Infection
Anti-MRSA agent 21 (Compound 27) has antibacterial activity against MRSA, with an MIC of 1 μM. Anti-MRSA agent 21 can damage bacterial cell membranes and increase reactive oxygen species .

HY-169132

*Anti-MRSA* agent 17**	Bacterial	Infection Inflammation/Immunology
Anti-MRSA agent 17 (8) is an inhibitor against S. aureus (MRSA) BPL (SaBPL), with a K_i of 10.3 nM .

HY-169160

*Anti-MRSA* agent 18**	Bacterial	Infection
Anti-MRSA agent 18 (E17) is an inhibitor of *MRSA* with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death .

HY-147882

*Anti-MRSA* agent 6**	Bacterial	Infection
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent. Anti-MRSA agent 6 shows low cytoxicity for MCF-7, A549 cells .

HY-163505

*Anti-MRSA* agent 11**	Bacterial	Others
Anti-MRSA agent 11 suppresses fluoroquinolone-sensitive strain USA500 and -resistant MRSA isolate Mu50 (MIC =0.39 μg/mL). Anti-MRSA agent 11 displayes favorable in vivo half-life and safety profiles .

HY-146428

*Anti-MRSA* agent 4**	Bacterial	Infection
Anti-MRSA agent 4 (compound 7a) is a potent and selective growth inhibitor of Gram-positive Methicillin-resistant Staphylococcus aureus (MRSA), with MIC ≤ 0.26 µM. Anti-MRSA agent 4 exhibits no cytotoxic and no hemolytic activity in HEK293 cells .

HY-170847

*Anti-MRSA* agent 24**	Bacterial	Infection
Anti-MRSA agent 24 (compound 6K) is an antimicrobial agent that targets Staphylococcus aureus (MRSA), especially penicillin-resistant Staphylococcus aureus .

HY-144822

*Anti-MRSA* agent 2**	Bacterial	Infection
Anti-MRSA agent 2 (compound 14) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and relatively low cytotoxicity in normal cells. Anti-MRSA agent 2 has strong ability to destroy bacterial membrane and bind to genomic DNA .

HY-149013

*Anti-MRSA* agent 5**	Bacterial	Infection
Anti-MRSA agent 5 (B14) is a potent MRSA agent with MIC₅₀ values of 0.38 μg/mL and has low hERG activity with an IC₅₀ values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance .

HY-161803

*Anti-MRSA* agent 12**	Antibiotic Bacterial	Infection
Anti-MRSA agent 12 (Compound SM-5) is an antibiotic, which exhibits antibacterial activity against Staphylococcus aureus, S. epidermidis and Escherichia coli with MIC of 7.81, 7.81 and 62.5 μM. Anti-MRSA agent 12 inhibits the methicillin-resistant S. aureus (MRSA) through inhibition of biofilm formation .

HY-144823

*Anti-MRSA* agent 3**	Bacterial	Infection
Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA .

HY-161330

*Anti-MRSA* agent 10**	Bacterial	Infection
Anti-MRSA agent 10 (Compound 2d) is a Cephalosporin (HY-144229) derivative and exhibits antibacterial activity. Anti-MRSA agent 10 is slightly drug resistane and exhibits low cytotoxicity in cells HUVEC and HBZY-1 .

HY-149271

*Anti-MRSA* agent 7**	Bacterial DNA/RNA Synthesis Topoisomerase	Infection
Anti-MRSA agent 7 (Compound 12) is a potent antibacterial agent. Anti-MRSA agent 7 inhibits S. aureus DNA gyrase, E. coli DNA gyrase, S. aureus topo IV and E. coli topo IV with IC₅₀s of 0.185, 0.365, 0.341 and 0.059 μM, respectively .

HY-167841

*Anti-MRSA* agent 19**	Bacterial Antibiotic	Infection
Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against S. aureus. Anti-MRSA agent 19 is a active (median MIC=4 μg/mL) against 40 CDC isolates of different bacterial species containing various resistance factors, including Vancomycin (HY-B0671), aminoglycoside/Tetracycline (HY-A0107), and oxazolidinone resistance .

HY-142097

Glicophenone	Bacterial	Infection
Glicophenone is an antibacterial agent with MICs of both 32 μg/mL against MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623 and MSSA 209P .

HY-N3515

Multicaulisin	Bacterial	Infection
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial agent and has the potential for MRSA infections research .

HY-14737

Ceftaroline fosamil 2 Publications Verification TAK-599; PPI0903	Bacterial Antibiotic	Infection
Ceftaroline fosamil (TAK-599), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil can be used for the research of MRSA infection .

HY-18702

Targocil	Bacterial	Infection
Targocil functions as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) with MIC₉₀s of 2 μg/ mL for both MRSA and MSSA.

HY-14738

Ceftaroline fosamil (inner) TAK-599 free acid; PPI0903 free acid	Bacterial Antibiotic	Infection
Ceftaroline fosamil (inner) (TAK-599 free acid), a cephalosporin derivative, is an N-phosphono proagent of anti-methicillin-resistant Staphylococcus aureus (MRSA) T-91825. Ceftaroline fosamil (inner) can be used for the research of MRSA infection .

HY-163984

Antibacterial agent 240	Bacterial	Infection
Antibacterial agent 240 (compound 62-7c) is an antibacterial agent that can target multidrug-resistant (MDR) *MRSA* strains. Antibacterial agent 240 showed high biosafety and potent anti-infection activity in mouse pneumonia and mouse wound models of MRSA infection .

HY-N8151

Sanguisorbigenin	Bacterial	Infection
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA) .

HY-119528

Mansonone F	Bacterial	Infection
Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea .

HY-P3361

IDR-1018	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

HY-17626B

Alalevonadifloxacin hydrochloride WCK-2349 hydrochloride	Antibiotic	Infection
Alalevonadifloxacin (hydrochloride) (WCK-2349 (hydrochloride)) is a oraaly active anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotic .

HY-139679

Antibacterial agent 28	Bacterial	Infection
Antibacterial agent 28 is a potential antibacterial candidate for combating MRSA infections (MICs = 0.5–2 μg/mL).

HY-143326

Antibacterial agent 83	Bacterial	Infection
Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes .

HY-P5545

Lynronne-1	Bacterial	Infection
Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection .

HY-156009

CDFI	Others	Infection
CDFI is an inhibitor of the lipid II flippase MurJ. CDFI potentiates the activity of β-lactams against MRSA .

HY-N3789

Dunnianol	Bacterial	Infection
Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits *Staphylococcus aureus* and methicillin-resistant Staphylococcus aureus (MRSA).

HY-P5709

HG4	Bacterial	Infection Inflammation/Immunology
HG4 is a fast-acting antimicrobial peptide. HG4 shows anti-biofilm and anti-inflammatory activities. HG4 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 32-64?μg/mL). HG4 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-P5706

HG2	Bacterial	Infection Inflammation/Immunology
HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32?μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-78542

Deshydroxyethoxy ticagrelor AR-C124910	Bacterial	Infection Cardiovascular Disease
Deshydroxyethoxy ticagrelor (AR-C124910) is a metabolite of Ticagrelor (HY-10064) with antimicrobial and antiplatelet activities against MRSA .

HY-100180

Delpazolid 1 Publications Verification LCB01-0371	Bacterial Antibiotic	Infection
Delpazolid is a novel oxazolidinone antibiotic agent which can inhibit the growth of MSSA and *MRSA* with a MIC₉₀ of 2 μg/mL for both of them.

HY-142124

Kalimantacin A	Antibiotic Bacterial	Infection
Kalimantacin A is a potent antibiotic. Kalimantacin A shows antibacterial activity against staphylococcus including methicillin-resistant staphylococcus aureus (MRSA) .

HY-163716

Antibacterial agent 222	Bacterial	Infection
Antibacterial agent 222 ((R)-O30 (5)) is a antimicrobial agent that inhibits methicillin-resistant Staphylococcus aureus (MRSA) .

HY-14784

Bederocin REP8839	Bacterial	Infection
Bederocin (REP8839) is a Methionyl-tRNA synthetase inhibitor. Bederocin can be used in research of bacterial infection, including S. aureus and MRSA .

HY-101479

Iclaprim 3 Publications Verification AR-100	Bacterial Antibiotic	Infection
Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC₉₀ of 0.06 μg/mL.

HY-N13885

Amythiamicin A	Antibiotic Bacterial Parasite	Infection
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-B2157

Robenidine hydrochloride 1 Publications Verification	Bacterial Parasite	Infection
Robenidine hydrochloride is an anticoccidial agent which is also active against *MRSA* and VRE with MIC₅₀s of 8.1 and 4.7 μM, respectively.

Cat. No.	Product Name	Type

HY-69174

1-Amino-2,5-anhydro-1-deoxy-D-mannitol

Microbial Culture

1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition.

Cat. No.	Product Name	Target	Research Area

HY-125747

Actinomycin X2 1 Publications Verification Actinomycin V	Bacterial Antibiotic Apoptosis	Infection Cancer
Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of *MRSA* with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection .

HY-P3361

IDR-1018	Parasite Bacterial Antibiotic	Infection Inflammation/Immunology
IDR-1018 is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) .

HY-P5545

Lynronne-1	Bacterial	Infection
Lynronne-1 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 8-32 μg/mL for methicillin-resistant MRSA strains). Lynronne-1 reduces the bacterial load in MRSA infected wound murine model. Lynronne-1 is also effective against P. aeruginosa infection .

HY-P5709

HG4	Bacterial	Infection Inflammation/Immunology
HG4 is a fast-acting antimicrobial peptide. HG4 shows anti-biofilm and anti-inflammatory activities. HG4 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 32-64?μg/mL). HG4 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-P5706

HG2	Bacterial	Infection Inflammation/Immunology
HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32?μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .

HY-P5710

LCI peptide	Bacterial	Infection
LCI peptide is an antimicrobial peptide with antibacterial activity. LCI peptide is active against plant pathogens, Xanthomonas and Pseudomonas, including E. coli, Gentamicin-resistant MRSA and Xoo .

HY-P5737

ASP-1	Bacterial	Infection
ASP-1 is a strong antistaphylococcal peptide with minimum inhibitory concentrations (MICs) of the purified peptide against S. aureus and methicillin-resistant S. aureus (MRSA) ranged from 2 μg/mL to 64 μg/mL .

HY-P10345

OP-145	Bacterial	Infection
OP-145, an cathelicidin LL-37 derivative, is an antimicrobial peptide, and shows antibacterial activity against several MRSA strains. OP-145 can be used for research of chronic suppurative otitis media .

HY-P5547

Lynronne-3	Bacterial	Infection
Lynronne-3 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 32-128 μg/mL for methicillin-resistant MRSA strains). Lynronne-3 is also effective against P. aeruginosa infection

HY-P10681

Crabrolin	Bacterial	Infection
Crabrolin is a tridecapeptide that can be extracted from the venom of the European hornet (Vespa crabro). Crabrolin shows MIC/MBC of 2/2, 16/64, 4/8 μM, for S. aureus (NCTC 10788), MRSA (NCTC 12493) and E. faecium (NTCC 12697), respectively .

HY-P5546

Lynronne-2	Bacterial	Infection
Lynronne-2 is an antimicrobial peptide. Lynronne-1 is active against Gram-positive bacterials, including MDR strains (MIC: 32-256 μg/mL for methicillin-resistant MRSA strains). Lynronne-2 is also effective against P. aeruginosa infection

HY-P10695

Bac8c	Bacterial Antibiotic	Infection
Bac8c is an antimicrobial peptide with strong antibacterial activity against Gram-negative and Gram-positive bacteria. The MIC of Bac8c against S. aureus, MRSA, S. epidermidis, E. coli, and P. aeruginosa are 2, 8, 4, 4, and 4 μg/mL, respectively .

HY-146133

LA-Bac8c	Bacterial Antibiotic	Infection
LA-Bac8c is a Lipoic acid modified antimicrobial peptide with enhanced antimicrobial properties. LA-Bac8c inhibits S. aureus, MRSA, S. epidermidis, E. coli, and P. aeruginosa with MICs of 1, 4, 8, 8, and 8 μg/mL .

HY-P3078

Amphomycin	Bacterial Antibiotic	Infection
Amphomycin is a lipopeptide antibiotic that inhibits peptidoglycan synthesis and blocks cell wall development. Amphomycin exhibits potent antibacterial activities against methicillin-resistant S. aureus (MRSA), vancomycin-resistant enterococci (VRE), penicillin-gentamicin-erythromycin-resistant S. pneumonia, and linezolid-quinupristin-dalfopristin-resistant enterococci .

HY-P10539

Hp1404	Bacterial	Infection
Hp1404 is a novel cationic antimicrobial peptide. Hp1404 has specific inhibitory activity against Gram-positive bacteria, including Staphylococcus aureus (MRSA) resistant to Laburnetin (HY-N7382). Hp1404 has antimicrobial activity, low toxicity, and is not prone to drug resistance, and can be used in the research of antimicrobial agents .

HY-P3349

c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]	Bacterial	Infection
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .

HY-P3348

c[Arg-Arg-Arg-Arg-Dip-Dip-Dip]	Bacterial	Infection
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .

HY-P2358

PSMα3	Toll-like Receptor (TLR)	Inflammation/Immunology
PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) .

HY-P2358A

PSMα3 TFA	Toll-like Receptor (TLR)	Inflammation/Immunology
PSMα3 TFA is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 TFA penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 TFA is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8151

Sanguisorbigenin	Infection Triterpenes Structural Classification Classification of Application Fields Sanguisorba officinalis Linn. Terpenoids Source classification Rosaceae Plants Disease Research Fields	Bacterial
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA) .

HY-N1312

Sinapaldehyde	Infection Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Bacterial
Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μg/mL .

HY-142097

Glicophenone	Structural Classification Natural Products Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Bacterial
Glicophenone is an antibacterial agent with MICs of both 32 μg/mL against MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623 and MSSA 209P .

HY-N3515

Multicaulisin	Infection Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Morus multicaulis Plants Moraceae Disease Research Fields Isoflavones	Bacterial
Multicaulisin, a new Diels-Alder type adduct from Morus multicaulis roots, potently effects against Staphylococcus aureus (MRSA) isolates. Multicaulisin is an antibacterial agent and has the potential for MRSA infections research .

HY-119528

Mansonone F	Structural Classification Natural Products Source classification Plants Ulmaceae Ulmus davidiana Planch.	Bacterial
Mansonone F is a potent anti-MRSA sesquiterpenoid quinone that can be found in Thespesia populnea .

HY-N3789

Dunnianol	Infection Classification of Application Fields Source classification Lignans Illicium dunnianum Tutch. Phenols Polyphenols Illiciaceae Phenylpropanoids Plants Disease Research Fields	Bacterial
Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits *Staphylococcus aureus* and methicillin-resistant Staphylococcus aureus (MRSA).

HY-142124

Kalimantacin A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Kalimantacin A is a potent antibiotic. Kalimantacin A shows antibacterial activity against staphylococcus including methicillin-resistant staphylococcus aureus (MRSA) .

HY-N13885

Amythiamicin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Parasite
Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-N13881

Amythiamicin C	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Parasite
Amythiamicin C is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum .

HY-156198

Bottromycin A2	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Bottromycin A2 is a natural antibiotic. Bottromycin A2 is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) .

HY-N8186

(3R)-7,4’-Dihydrohomoisoflavanone	Infection Structural Classification Flavonoids Dracaena cambodiana Pierre ex Gagnep. Classification of Application Fields Flavonones Source classification Phenols Polyphenols Agavaceae Plants Disease Research Fields	Bacterial
(3R)-7,4’-Dihydrohomoisoflavanone is a natural product with antibacterial activities against *S. aureus* and methicillin-resistant Staphylococcus aureus (MRSA) .

HY-116168

Aldecalmycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Aldecalmycin is an antibiotic showing antimicrobial activities against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MICs values of 6.25-25 μg/mL .

HY-N3920

Gancaonin G	Structural Classification Flavonoids Flavones Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Bacterial
Gancaonin G is a 6-prenylated isoflavanone that can be isolated from Glycyrrhiza uralensis. Gancaonin G has antibacterial activity against Streptococcus mutants and MRSA strains .

HY-N2058

Neogambogic acid	Infection Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields	Bacterial Apoptosis
Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA) .

HY-107164

Thiomarinol A 4-Hydroxythiomarinol C	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Thiomarinol A (4-Hydroxythiomarinol C) is a potent antibiotic. Thiomarinol A is a hybrid of dithiolopyrrolone and marinolic acid. Thiomarinol A shows antimicrobial activity. Thiomarinol A inhibits MRSA IleRS in a dose-dependent with a K_i ^app value of 19 nM .

HY-101472

Closthioamide	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Closthioamide is a potent inhibitor of bacterial DNA gyrase and highly active against Ec, MRSA, VRE and Mv), with MICs of 9.00 μM, 0.58 μM, 0.58 μM and 72.03 μM respectively.

HY-161935

6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid	Structural Classification Lysimachia tengyuehensis Hand.-Mazz. Antibiotics Source classification Plants Primulaceae Other Antibiotics	Bacterial
6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid (Compound 2) exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin enterococci (VRE). 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid interfers with the integrity and function of the bacterial cell membrane, and affects metabolism in MRSA. 6-(12-Tridecene-1-yl)-2,4-Dihydroxy benzoic acid exhibits anti-inflammatory and anti-infective efficacy, and promotes angiogenesis in mice .

HY-N8464

Juncuenin D	Structural Classification Natural Products Juncaceae Source classification Plants Juncus acutus L.	Bacterial
Juncuenin D induces caspase-3-mediated cytotoxicity in HT22 cells. Juncuenin D also has anti-bacterial activity against MRSA strains. Juncuenin D can be isolated from J. effusus .

HY-N10765

Salvinolone	Structural Classification Stilbenes Terpenoids Labiatae Source classification Diterpenoids Plants Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Bacterial
Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC₅₀ of 47.6 μM against the HL-60 tumor cell line for 72 h .

HY-127155

Kigamicin C	Structural Classification Microorganisms Source classification Lignans Phenylpropanoids	Bacterial Antibiotic
Kigamicin C is an anti-tumor antibiotic that selectively kills pancreatic cancer PANC-1 cells only in nutrient-poor conditions. Kigamicin C has antimicrobial activity against Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) .

HY-N6908

Continentalic acid	Infection Structural Classification Classification of Application Fields Terpenoids Aralia continentalis Kitagawa Source classification Diterpenoids Plants Inflammation/Immunology Disease Research Fields Araliaceae	Bacterial
Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 µg/mL against S. aureus, including the Methicillin (HY-121544) susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus (MRSA) standard strains .

HY-N9690

Longistyline A Longistylin A	Monophenols Leguminosae Phenols Plants Cajanus cajan (L.) Millsp.	Bacterial
Longistyline A (Longistylin A) is a natural stilbene, it can be isolated from leaves of Cajanus cajan. Longistyline A shows antimicrobial activity against *MRSA* with an MIC value of 1.56 μg/mL. Longistyline A shows neuroprotective effects, it can be used for the research of infection and nerve diseases .

HY-N7382

Laburnetin	Laburnum anagyroides Medic. Structural Classification Flavonoids Leguminosae Source classification Plants Isoflavones	Bacterial
Laburnetin is a kind of isoflavone antibacterial agent. Laburnetin has antibacterial activity against fungi and S. vesicarium. Laburnetin intensifies the susceptibility of Methicillin (HY-121544) resistant Staphylococcus aureus (MRSA) strains to Methicillin. Laburnetin can be used to control pests of cultivated species .

HY-124199

Cephalochromin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Cephalochromin is an antibiotic and an inhibitor for bacterial fatty acid synthase (FabI). Cephalochromin inhibits FabI of Staphylococcus aureus and Escherichia coli with IC₅₀ of 1.9 and 1.8 μM. Cephalochromin inhibits gram-positive methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA), with MIC of 2-8 µg/mL .

HY-N2245

Schisandrone	Structural Classification Monophenols Classification of Application Fields Source classification Lignans Phenols Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Cancer	CD74
Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera . Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia .

HY-A0097

Teicoplanin 1 Publications Verification Antibiotic MDL-507; MDL-507	Infection Structural Classification Microorganisms Source classification Polyphenols Disease Research Fields	Bacterial Antibiotic
Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .

HY-A0097A

Teicoplanin sodium Antibiotic MDL-507 sodium; MDL-507 sodium	Structural Classification Source classification Phenols Polyphenols Endogenous metabolite	Antibiotic HIV SARS-CoV
Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .

HY-125365

Rifamycin S 1 Publications Verification	Infection Quinones Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Phenols Naphthalene Quinones Disease Research Fields	Bacterial Reactive Oxygen Species Antibiotic
Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including *MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS)* and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .

HY-N6908R

Continentalic acid (Standard)	Structural Classification Terpenoids Aralia continentalis Kitagawa Source classification Diterpenoids Plants Araliaceae	Bacterial
Continentalic acid (Standard) is the analytical standard of Continentalic acid. This product is intended for research and analytical applications. Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 μg/mL against S. aureus, including the Methicillin (HY-121544) susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant Staphylococcus aureus (MRSA) standard strains .

HY-N11879

6-C-Methylquercetin-3,4'-dimethyl ether	Structural Classification Flavonols Flavonoids Leguminosae Source classification Bauhinia thonningii Plants	Bacterial Antibiotic
6-C-Methylquercetin-3,4'-dimethyl etheris a flavonol derivative isolated from the leaves of Bauhinia thonningii Schum. 6-C-Methylquercetin-3,4'-dimethyl ether has antibacterial activity against Gram-negative multidrug-resistant bacteria and against methicillin-resistant Staphylococcus aureus (MRSA) strains .

HY-N12261

Benastatin B	Structural Classification Microorganisms Source classification Phenols Polyphenols	Glutathione S-transferase Bacterial
Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC₅₀ of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC₅₀ of 79 μg/mL .

HY-A0279

Pristinamycin Pristinamycine	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	Bacterial Antibiotic
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .

HY-N15272

Artocarpesin	Structural Classification Flavanonols Flavonoids Source classification Plants Moraceae	Bacterial COX NO Synthase Reactive Oxygen Species p38 MAPK
Artocarpesin is a flavonoid compound. Artocarpesin has inhibitory effects on methicillin-resistant Staphylococcus aureus (MRSA). Artocarpesin inhibits the production of NO, PGE₂ and ROS by inhibiting COX-2 and iNOS expression, and plays an anti-inflammatory role. In addition, Artocarpesin inhibits platelet aggregation by inhibiting cyclic nucleotides and MAPKs, which can be used in the study of cardiovascular diseases .

HY-13067

Celastrol Maximum Cited Publications 41 Publications Verification Tripterine; Tripterin	Triterpenes Structural Classification Classification of Application Fields Anti-aging Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants Inflammation/Immunology Disease Research Fields Cancer	Proteasome Autophagy Mitophagy Apoptosis Endogenous Metabolite Antibiotic Bacterial
Celastrol (Tripterine;Tripterin) is a proteasome inhibitor which potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with IC₅₀ of 2.5 μM. In addition, Celastrol is also an antibiotic with potent antimicrobial activity against standard and clinical methicillin-resistant Staphylococcus aureus (MRSA) strains, inducing oxidative stress and inhibiting DNA synthesis by binding to P5CDH .

HY-121000

Albocycline Ingramycin	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Bacterial
Albocycline (Ingramycin) is a macrolide antibiotic, which exhibits antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin (HY-B0671)-intermediate (VISA), and Vancomycin (HY-B0671)-resistant S. aureus (VRSA) strains with MICs ranging from 0.5 to 1.0 μg/mL. Albocycline exhibits no toxicity to human cells at concentration of ≤64 μg/mL .

HY-125365R

Rifamycin S (Standard)	Quinones Structural Classification Monophenols Microorganisms Source classification Phenols Naphthalene Quinones	Bacterial Reactive Oxygen Species Antibiotic
Rifamycin S (Standard) is the analytical standard of Rifamycin S. This product is intended for research and analytical applications. Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy .

HY-P2358

PSMα3	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Toll-like Receptor (TLR)
PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) .

HY-B0914

10-Undecenoic acid,98% (stabilized with TBC) 2 Publications Verification Undecylenic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Fungal Amyloid-β Reactive Oxygen Species Proteasome Bacterial
10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-B0914A

10-Undecenoic acid zinc salt 2 Publications Verification Zinc undecylenate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Fungal Bacterial Amyloid-β Reactive Oxygen Species Proteasome
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N10907

4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl-	Structural Classification Alkaloids Source classification Rutaceae Plants Tetradium ruticarpum (A. Jussieu) T. G. Hartley	Bacterial
4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- (compound 2) is a quinolone alkaloid that can be isolated from Cnidium. 4(1H)-Quinolinone, 1-methyl-2-(5Z)-5-undecen-1-yl- has methicillin-resistant Staphylococcus aureus (MRSA) activity, with MIC values of 32 μg/mL (ATCC 33591) and 16 μM/mL (ATCC 25923), respectively .

HY-N2187

Deoxyshikonin 2 Publications Verification	Infection Cardiovascular Disease Quinones Structural Classification Classification of Application Fields Plants Naphthalene Quinones Boraginaceae Disease Research Fields Arnebia euchroma (Royle) Johnst.	Bacterial HIF/HIF Prolyl-Hydroxylase PI3K Apoptosis
Deoxyshikonin increases the expression of VEGF-C and VEGF-A mRNA in HMVEC-dLy, promotes HIF-1α and HIF-1β subunit interaction and binds to specific DNA sequences targeted by HIF. Deoxyshikonin inhibited colorectal cancer (CRC) through the PI3K/Akt/mTOR pathway. Deoxyshikonin has proangiogenesis effect and antitumor activity. Deoxyshikonin is an antibacterial agent against methicillin-resistant S. aureus (MRSA) and S. pneumonia (MIC=17 μg/mL) .

HY-B0914R

10-Undecenoic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Fungal Endogenous Metabolite Antibiotic
10-Undecenoic acid (Standard) is the analytical standard of 10-Undecenoic acid. This product is intended for research and analytical applications. 10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-B0914AR

10-Undecenoic acid (zinc salt) (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal DNA/RNA Synthesis
10-Undecenoic acid (zinc salt) (Standard) is the analytical standard of 10-Undecenoic acid (zinc salt). This product is intended for research and analytical applications. 10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .

HY-N10834

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol	Structural Classification Natural Products Source classification Plants Compositae Erythrina sigmoidea Hua	Bacterial
(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be isolated from the roots of Atractylodes japonica. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol has anti-methicillin-resistant Staphylococcus aureus (MRSA) activity with MIC values of 4-32 μg/mL. (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol can be used for the research of bacterial infection . (6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Chemical Structure

HY-B2157S

Robenidine-d8 hydrochloride
Robenidine-d₈ (hydrochloride) is the deuterium labeled Robenidine hydrochloride. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.

HY-101479S

Iclaprim-d6
Iclaprim-d₆ (AR-100-d6) is the deuterium labeled Iclaprim. Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.

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