Search Result

Results for "

aminoglycosides

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (1) Amyloid-β (1) Antibiotic (65) ATP Synthase (1) Bacterial (60) Caspase (1) CFTR (1) Drug Intermediate (1) Drug Metabolite (1) Endothelin Receptor (1) Fluorescent Dye (1) Fungal (7) GCGR (3) GLP Receptor (2) GnRH Receptor (1) Isotope-Labeled Compounds (1) Parasite (8) PARP (1) PDI (1) Phospholipase (2) Radionuclide-Drug Conjugates (RDCs) (2) Renin (1) Somatostatin Receptor (3) TRP Channel (1) Tyrosinase (2)
By Research Areas:	Cancer (21) Cardiovascular Disease (3) Endocrinology (2) Infection (67) Inflammation/Immunology (5) Metabolic Disease (4) Neurological Disease (5)

By Targets:

Adenylate Cyclase (1)

Amyloid-β (1)

Antibiotic (65)

ATP Synthase (1)

Bacterial (60)

Caspase (1)

CFTR (1)

Drug Intermediate (1)

Drug Metabolite (1)

Endothelin Receptor (1)

Fluorescent Dye (1)

Fungal (7)

GCGR (3)

GLP Receptor (2)

GnRH Receptor (1)

Isotope-Labeled Compounds (1)

Parasite (8)

PARP (1)

PDI (1)

Phospholipase (2)

Radionuclide-Drug Conjugates (RDCs) (2)

Renin (1)

Somatostatin Receptor (3)

TRP Channel (1)

Tyrosinase (2)

By Research Areas:

Cancer (21)

Cardiovascular Disease (3)

Endocrinology (2)

Infection (67)

Inflammation/Immunology (5)

Metabolic Disease (4)

Neurological Disease (5)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1915

Micronomicin Gentamicin C2b; Antibiotic XK-62-2; Sagamicin	Antibiotic Bacterial	Infection
Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities .

HY-125685

Germacrene D	Bacterial Fungal	Cancer
Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles .

HY-B1329

Apramycin sulfate 3 Publications Verification Nebramycin II sulfate	Bacterial Antibiotic	Infection
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .

HY-N7449

Neamine	Antibiotic Bacterial	Infection Cardiovascular Disease Neurological Disease Cancer
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-108718

G-418 Geneticin; Antibiotic G-418	Bacterial Parasite Antibiotic	Infection
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .

HY-129677

ORC-13661 hydrochloride	TRP Channel	Others
ORC-13661 hydrochloride is a hair cell protector. ORC-13661 hydrochloride protects sensory hair cells from aminoglycoside and Cisplatin (HY-17394) ototoxicity. ORC-13661 hydrochloride is a reversibly mechanoelectrical transducer (MET) channel permeant blocker .

HY-N14386

Istamycin Y0	Bacterial	Infection
Istamycin Y0 is an aminoglycoside antibiotic. Istamycin Y0 can be found in Streptomyces tenjimariensis ATCC 31603. Istamycin Y0 has only weak antibacterial activity against a few bacteria .

HY-121474

Dactimicin SF-2052	Antibiotic Bacterial	Infection
Dactimicin is a pseudodisaccharide aminoglycoside. Dactimicin is an antibiotic that can inhibit the growth of methicillin-susceptible S. aureus isolates and coagulase-negative staphylococci with MIC₅₀s of 2 μg/mL. Dactimicin is active against organisms possessing aminoglycoside-modifying enzymes .

HY-150520

Neomycin	Antibiotic	Infection Cancer
Neomycin is an aminoglycoside antibiotic. Neomycin can be used for the research of external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt .

HY-B1329R

Apramycin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-B0470

Neomycin sulfate 40+ Cited Publications	Bacterial Antibiotic Phospholipase	Infection Cancer
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-115349

Neamine tetrahydrochloride	Antibiotic Bacterial	Infection Neurological Disease Cancer
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .

HY-167841

Anti-MRSA agent 19	Bacterial Antibiotic	Infection
Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against S. aureus. Anti-MRSA agent 19 is a active (median MIC=4 μg/mL) against 40 CDC isolates of different bacterial species containing various resistance factors，including Vancomycin (HY-B0671)，aminoglycoside/Tetracycline (HY-A0107)，and oxazolidinone resistance .

HY-106668

Isepamicin Sch 21420	Antibiotic Bacterial	Infection
Isepamicin (Sch 21420) is an aminoglycoside antibacterial. Isepamicin has better activity against strains producing type I 6'-acetyltransferase. Isepamicin’s antibacterial spectrum includes Enterobacteriaceae and staphylococci. Anaerobes, Neisseriaceae and streptococci are resistant. Isepamicin exhibits a strong concentration-dependent bactericidal effect, a long post-antibiotic effect (several hours) and induces adaptive resistance .

HY-B0470R

Neomycin (sulfate) (Standard)	Bacterial Antibiotic Phospholipase	Infection Cancer
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-16955

Plazomicin ACHN 490	Antibiotic Bacterial	Infection Inflammation/Immunology
Plazomicin (ACHN 490) is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin has in vitro activity against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .

HY-122350

Dactimicin sulfate SF-2052 sulfate	Antibiotic	Infection
Dactimicin sulfate (SF-2052 sulfate) is an antibiotic produced by Dactylosporangium matsuzakiense and belongs to the fortimicin antibiotic family. Dactimicin sulfate is an aminoglycoside antibiotic containing a carboximido group and inhibits protein synthesis by binding to the 30S ribosomal subunit of bacteria. Dactimicin sulfate can be used in research on infections caused by sensitive bacteria .

HY-16955A

Plazomicin sulfate 1 Publications Verification ACHN 490 sulfate	Antibiotic Bacterial	Infection Inflammation/Immunology
Plazomicin (ACHN 490) sulfate is a potent aminoglycoside antibiotic in the fight against antimicrobial resistance. Plazomicin sulfate has in vitro activity against several multi-drug-resistant organisms, including carbapenem-resistant Enterobacteriaceae. Plazomicin sulfate has the potential to be used for multi-drug-resistant complicated urinary tract infections (cUTIs) or in combination for serious carbapenem-resistant Enterobacteriaceae infections .

HY-N125722

Venturicidin A Aabomycin A1	ATP Synthase Antibiotic	Infection
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.

HY-B0509

Amikacin hydrate 10+ Cited Publications BAY 41-6551 hydrate	Bacterial Antibiotic	Infection Cancer
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-B0509B

Amikacin disulfate 10+ Cited Publications BAY 41-6551 disulfate	Bacterial Antibiotic	Infection Cancer
Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-107813

Amikacin sulfate 10+ Cited Publications BAY 41-6551 sulfate	Bacterial Antibiotic	Infection Cancer
Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-B0509BR

Amikacin (disulfate) (Standard)	Bacterial Antibiotic	Infection Cancer
Amikacin (disulfate) (Standard) is the analytical standard of Amikacin (disulfate). This product is intended for research and analytical applications. Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin-and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-B0472

Streptomycin sulfate 30+ Cited Publications	Bacterial Antibiotic	Infection
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B1743

Puromycin Maximum Cited Publications 238 Publications Verification CL13900	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-17558

Apramycin Nebramycin II	Bacterial Antibiotic	Infection
Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-B0490

Hygromycin B 20+ Cited Publications Hygrovetine	Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-127054

Netilmicin Sch 20569	Antibiotic Bacterial	Infection
Netilmicin (Sch 20569) is an antibiotic. Netilmicin exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL .

HY-W016456

5-Bromopentanoic acid	Drug Intermediate	Others
5-Bromopentanoic acid can be used for the synthesis of inhibitors for aminoglycoside resistant bacteria .

HY-B1241

Dihydrostreptomycin sulfate DHSM sulfate	Bacterial Antibiotic	Infection
Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep.

HY-B1864C

Kasugamycin sulfate Ksg sulfate	Antibiotic Fungal	Infection
Kasugamycin (sulfate) is an aminoglycoside antibiotic that can be used to treat rice blast caused by fungi .

HY-B1743S

Puromycin-d3 3 Publications Verification CL13900-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B0755

Etimicin sulfate	Antibiotic	Infection
Etimicin (sulfate), a fourth-generation aminoglycoside antibiotic, is now widely clinically used due to its high efficacy and low toxicity.

HY-B1222

Sisomicin sulfate 5 Publications Verification	Bacterial Antibiotic	Infection
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.

HY-B1222A

Sisomicin 5 Publications Verification Antibiotic 6640; Rickamicin	Bacterial Antibiotic	Infection
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-B2094

Arbekacin	Antibiotic Bacterial	Infection
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria .

HY-B1174

Bekanamycin Kanamycin B	Antibiotic Bacterial	Infection
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-B0472R

Streptomycin (sulfate) (Standard)	Bacterial Antibiotic	Infection
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-W129471R

2-Pentadecanone (Standard)	Bacterial	Others
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B0490R

Hygromycin B (Standard)	Bacterial Fungal Antibiotic Parasite	Infection
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-A0086

Netilmicin sulfate SCH-20569 sulfate	Bacterial Antibiotic	Infection
Netilmicin (sulfate) (SCH-20569 (sulfate)) is an active aminoglycoside antibiotic against most Gram-negative and some Gram-positive bacteria, including certain strains resistant to gentamicin.

HY-B0441A

Tobramycin sulfate 5+ Cited Publications Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate	Bacterial Antibiotic	Infection Cancer
Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .

HY-142127

Ribostamycin Vistamycin; SF-733	Bacterial Antibiotic PDI	Infection
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-N14398

Sannamycin E	Bacterial	Infection
Sannamycin E is an aminoglycoside antibiotic. Sannamycin E can be found in Streptomyces sannanensis KC-7038. Sannamycin E has weak antibacterial activity against Gram-positive bacteria .

HY-17561

G-418 disulfate 35+ Cited Publications Geneticin sulfate; Antibiotic G-418 sulfate	Bacterial Antibiotic	Infection
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .

HY-100589

Isepamicin sulfate Sch 21420 sulfate	Bacterial Antibiotic	Infection
Isepamicin sulfate (Sch 21420 sulfate) is a broad spectrum aminoglycoside antibiotic. Isepamicin sulfate exhibits considerable antimicrobial activity against Gram-negative non-fermenters in a region with high antimicrobial resistance .

HY-123162A

Astromicin disulfate Fortimicin A disulfate; KW-1070 disulfate	Antibiotic Bacterial	Infection
Astromicin disulfate is a water-soluble aminoglycoside antibiotic that can be isolated from the genus Micromonospora. Astromicin disulfate exhibits broad spectrum antibacterial activity against gram positive and negative bacteria .

HY-B1222AR

Sisomicin (Standard)	Bacterial Antibiotic	Infection
Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-N15029

Destomycin A	Antibiotic Bacterial Fungal Parasite Adenylate Cyclase	Infection
Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .

HY-N14365

Sannamycin J	Bacterial	Infection
Sannamycin J is an aminoglycoside antibiotic. Sannamycin J can be found in Streptomyces sannanensis sp. KC-7038. Sannamycin J has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .

Cat. No.	Product Name

HY-L042

Glycoside Compound Library

809 compounds

Glycosides are compounds in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Many biologically active compounds are glycosides. Glycosides comprise several important classes of compounds such as hormones, sweeteners, alkaloids, flavonoids, antibiotics, etc. The glycosidic residue can be crucial for their activity or can only improve pharmacokinetic parameters. Glycosides, which exhibit anti-inflammatory, anti-infection, anti-cancer and anti-oxidative properties, play numerous important roles in living organisms, such as streptomycin, as an aminoglycoside antibiotic, has anti-infection activity. Anthracyclines possess good antibacterial and anti-cancer activities.

MCE Glycoside Compound Library contains a unique collection of 809 glycoside compounds and is a useful tool to discovery glycoside drugs.

Cat. No.	Product Name	Type

HY-D1434

FM1-43 3 Publications Verification	Fluorescent Dyes/Probes
FM1-43 is a very lipophilic, water-soluble styrene dyes, can specifically bind to cell membranes and inner membrane organelles to produce fluorescence. FM1-43 is widely used in endocytic and exospic membrane structure markers.

Cat. No.	Product Name	Target	Research Area

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P5362

NODAGA-LM3	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-P10876

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5362A

NODAGA-LM3 TFA	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

Cat. No.	Product Name

HY-K1055

Kanamycin sulfate (100x), Sterile
Kanamycin sulfate is an aminoglycoside antibiotic purified from Streptomyces kanamyceticus. It acts by binding to the 30S subunit of the bacterial ribosome and inhibiting protein synthesis in susceptible bacteria.

HY-K1056

G418 Selective Antibiotic, Sterile 3 Publications Verification
MCE G418 Selective Antibiotic, Sterile is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1915

Micronomicin Gentamicin C2b; Antibiotic XK-62-2; Sagamicin	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Disease Research Fields	Antibiotic Bacterial
Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities .

HY-125685

Germacrene D	Classification of Application Fields Vigna mungo (L.) Hepper Plants Compositae Disease Research Fields Cancer	Bacterial Fungal
Germacrene D is isolated from Solidago canadensis. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles .

HY-B1329

Apramycin sulfate 3 Publications Verification Nebramycin II sulfate	Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics Cancer	Bacterial Antibiotic
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .

HY-N7449

Neamine	Infection Cardiovascular Disease Classification of Application Fields Disease Research Fields	Antibiotic Bacterial
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities .

HY-B0470

Neomycin sulfate 40+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields	Bacterial Antibiotic Phospholipase
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-N125722

Venturicidin A Aabomycin A1	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields	ATP Synthase Antibiotic
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.

HY-N14386

Istamycin Y0	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Istamycin Y0 is an aminoglycoside antibiotic. Istamycin Y0 can be found in Streptomyces tenjimariensis ATCC 31603. Istamycin Y0 has only weak antibacterial activity against a few bacteria .

HY-121474

Dactimicin SF-2052	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Dactimicin is a pseudodisaccharide aminoglycoside. Dactimicin is an antibiotic that can inhibit the growth of methicillin-susceptible S. aureus isolates and coagulase-negative staphylococci with MIC₅₀s of 2 μg/mL. Dactimicin is active against organisms possessing aminoglycoside-modifying enzymes .

HY-B1329R

Apramycin (sulfate) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Apramycin (sulfate) (Standard) is the analytical standard of Apramycin (sulfate). This product is intended for research and analytical applications. Apramycin (EBL 1003) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .

HY-B0470R

Neomycin (sulfate) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Anticancer Other Antibiotics	Bacterial Antibiotic Phospholipase
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-B0472

Streptomycin sulfate 30+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields	Bacterial Antibiotic
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B1743

Puromycin Maximum Cited Publications 238 Publications Verification CL13900	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic Parasite
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B0490

Hygromycin B 20+ Cited Publications Hygrovetine	Structural Classification Antifungal Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields	Bacterial Fungal Antibiotic Parasite
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-B1222

Sisomicin sulfate 5 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.

HY-B1222A

Sisomicin 5 Publications Verification Antibiotic 6640; Rickamicin	Structural Classification Polysaccharides Microorganisms Source classification Saccharides	Bacterial Antibiotic
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-B1174

Bekanamycin Kanamycin B	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-B0472R

Streptomycin (sulfate) (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics Plant agriculture research	Bacterial Antibiotic
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-W129471R

2-Pentadecanone (Standard)	Structural Classification Cupressaceae Thuja occidentalisLinn. Ketones, Aldehydes, Acids Source classification Plants	Bacterial
Streptomycin (sulfate) (Standard) is the analytical standard of Streptomycin (sulfate). This product is intended for research and analytical applications. Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-B0490R

Hygromycin B (Standard)	Structural Classification Plant Cell Culture Microorganisms Antifungal Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics	Bacterial Fungal Antibiotic Parasite
Hygromycin B (Standard) is the analytical standard of Hygromycin B. This product is intended for research and analytical applications. Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

HY-B0441A

Tobramycin sulfate 5+ Cited Publications Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .

HY-142127

Ribostamycin Vistamycin; SF-733	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-N14398

Sannamycin E	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Sannamycin E is an aminoglycoside antibiotic. Sannamycin E can be found in Streptomyces sannanensis KC-7038. Sannamycin E has weak antibacterial activity against Gram-positive bacteria .

HY-17561

G-418 disulfate 35+ Cited Publications Geneticin sulfate; Antibiotic G-418 sulfate	Structural Classification Antifungal Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields	Bacterial Antibiotic
G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells .

HY-B1222AR

Sisomicin (Standard)	Structural Classification Polysaccharides Microorganisms Source classification Saccharides	Bacterial Antibiotic
Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .

HY-N15029

Destomycin A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial Fungal Parasite Adenylate Cyclase
Destomycin A is an aminoglycoside antibiotic with antibacterial (Gram-positive bacteria, Gram-negative bacteria), antifungal and anthelmintic activities. Destomycin A inhibits the polypeptide synthesis in cells of Escherichia coli and stimulation of adenylate cyclase in animal tissues .

HY-N14365

Sannamycin J	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Sannamycin J is an aminoglycoside antibiotic. Sannamycin J can be found in Streptomyces sannanensis sp. KC-7038. Sannamycin J has weak antibacterial activity against Gram-positive bacteria and Gram-negative bacteria .

HY-B1174R

Bekanamycin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-A0276

Gentamicin sulfate 35+ Cited Publications	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Animal Husbandry Mammalian Cell Culture Disease Research Fields	Bacterial Antibiotic
Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC₅₀ of 0.57 mM .

HY-B0441

Tobramycin 5+ Cited Publications Nebramycin Factor 6; Deoxykanamycin B	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-B1222R

Sisomicin (sulfate) (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [4].

HY-108307

Micronomicin sulfate Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Structural Classification Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-130066

Fortimicin C	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Antibiotic Bacterial
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .

HY-B0441R

Tobramycin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-B0956

Paromomycin sulfate 3 Publications Verification Aminosidine sulfate	Structural Classification Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields	Antibiotic Parasite Bacterial
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-A0276R

Gentamicin (sulfate) (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Resistance Selection Source classification Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics Plant agriculture research	Bacterial Antibiotic
Gentamicin (sulfate) (Standard) is the analytical standard of Gentamicin (sulfate). This product is intended for research and analytical applications. Gentamicin sulfate, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC50 of 0.57 mM .

HY-N7224

N-Formylfortimicin A SF-1854	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Antibiotic
N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases .

HY-B0856

Validamycin A 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Fungal Tyrosinase Antibiotic
Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1?μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a K_i of 5.893 mM .

HY-B0856R

Validamycin A (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Fungal Tyrosinase Antibiotic
Validamycin A (Standard) is the analytical standard of Validamycin A. This product is intended for research and analytical applications. Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus, with a MIC of 1 μg/mL . Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani, with an IC₅₀ of 72 μM . Validamycin A is a reversible tyrosinase inhibitor, with a Ki of 5.893 mM .

HY-N0677AR

Kalii Dehydrographolidi Succinas (Standard)	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	Antibiotic
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-B0956R

Paromomycin (sulfate) (Standard)	Structural Classification Plant Cell Culture Microorganisms Antibiotics Resistance Selection Source classification Mammalian Cell Culture Anti-parasitic Antibacterial Disease Research Other Antibiotics	Antibiotic Parasite Bacterial
Paromomycin (sulfate) (Standard) is the analytical standard of Paromomycin (sulfate). This product is intended for research and analytical applications. Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis?by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

Cat. No.	Product Name	Chemical Structure