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Results for "

brain tissue

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adrenergic Receptor (2) Akt (1) Amino Acid Derivatives (1) Amyloid-β (1) Antibiotic (1) Apoptosis (4) Autophagy (1) Bcl-2 Family (1) Biochemical Assay Reagents (4) Caspase (1) Cholinesterase (ChE) (2) Endogenous Metabolite (42) Ferroptosis (1) Fluorescent Dye (2) Glutathione Peroxidase (1) HDAC (1) HIF/HIF Prolyl-Hydroxylase (1) Histone Methyltransferase (2) HMG-CoA Reductase (HMGCR) (1) Isotope-Labeled Compounds (17) Keap1-Nrf2 (1) LRRK2 (1) mAChR (2) Melatonin Receptor (1) Mitochondrial Metabolism (1) MMP (2) Monoamine Oxidase (1) Monoamine Transporter (2) Na+/K+ ATPase (1) Neurokinin Receptor (1) Neurotensin Receptor (1) PARP (1) Phosphodiesterase (PDE) (1) Potassium Channel (1) ROS Kinase (1) Sirtuin (1) Sodium Channel (2) Toll-like Receptor (TLR) (1) TRP Channel (1)
By Research Areas:	Cancer (10) Cardiovascular Disease (6) Endocrinology (2) Infection (1) Inflammation/Immunology (7) Metabolic Disease (40) Neurological Disease (63)
Oligonucleotides:	Aptamers (1) Solubilizing Agents (1) Freeze-drying Protective Agents (1)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: MALT1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0714

Tetrazolium Red 3 Publications Verification 2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC	Biochemical Assay Reagents	Cardiovascular Disease
Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .

HY-W017443

L-Asparagine monohydrate 3 Publications Verification	Endogenous Metabolite	Metabolic Disease Cancer
L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W105835

Magnesium citrate Trimagnesium dicitrate	Toll-like Receptor (TLR)	Neurological Disease
Magnesium citrate is a magnesium salt form that provides efficient penetration into brain and muscle tissue. Magnesium citrate increases pain threshold and reduces TLR4 concentration in the brain. Orally active .

HY-N0229

L-Alanine 1 Publications Verification Alanine	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-B0099

Edaravone Maximum Cited Publications 18 Publications Verification MCI-186	MMP Apoptosis	Neurological Disease
Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.

HY-148465

Gadoteric acid	Biochemical Assay Reagents	Cardiovascular Disease Cancer
Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution .

HY-N0667

L-Asparagine 3 Publications Verification (-)-Asparagine; Asn; Asparamide	Endogenous Metabolite	Neurological Disease Cancer
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity .

HY-W017443R

L-Asparagine monohydrate (Standard)	Endogenous Metabolite	Metabolic Disease
L-Asparagine (monohydrate) (Standard) is the analytical standard of L-Asparagine (monohydrate). This product is intended for research and analytical applications. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-145858

Chalcones A-N-5	Ferroptosis	Cancer
Chalcones A-N-5 is a trihydroxy chalcone derivative compound. Chalcones A-N-5 doesn’t show cytotoxicity at the concentration lower than 100 µM (with IC₅₀ > 1 mM), but has a significant effect on promoting cell proliferation. Chalcones A-N-5 potentially promotes neuronal cell growth in the damaged brain tissue. Chalcones A-N-5 also inhibits ferroptosis induced by RSL or erastin and reduces the lipid peroxidation levels induced by Aβ1-42 protein aggregation. Chalcones A-N-5 is a promising molecular skeleton candidate for further development of lead compound for in vivo test to research AD .

HY-129793

L-156903	Neurotensin Receptor	Neurological Disease
L-156903 potently inhibits neurotensin (NT) binding to brain tissue .

HY-118934

Novocebrin	Others	Neurological Disease Metabolic Disease
Novocebrin is a central nervous system activator that effectively increases brain and femoral blood flow in dogs. In addition, Novocebrin inhibits triglyceride biosynthesis in porcine adipose tissue .

HY-N0667S5

L-Asparagine-d3 hydrate	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Asparagine-d₃ (hydrate) is the deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-106110

OP-2507	Others	Metabolic Disease
OP-2507 is a prostacyclin analog. OP-2507 can increase brain glucose levels in mice, suppress the breakdown of energy metabolism under hypoxic conditions, and has a protective effect against changes in cyclic nucleotides in hypoxic brain tissue (specifically, an increase in cyclic AMP and a decrease in cyclic GMP). OP-2507 provides protective effects against brain hypoxia and edema .

HY-112636

Astrophloxine	Amyloid-β	Others
Astrophloxine is a fluorescent imaging probe capable of targeting antiparallel dimers. Astrophloxine can be used to detect aggregated Aβ in brain tissue and cerebrospinal fluid samples of Alzheimer's disease (AD) mice .

HY-N0667S2

L-Asparagine-15N2 monohydrate (-)-Asparagine-¹⁵N₂ monohydrate; Asn-¹⁵N₂ monohydrate; Asparamide-¹⁵N₂ monohydrate	Endogenous Metabolite	Neurological Disease
L-Asparagine- ¹⁵N₂ (monohydrate) is the ¹⁵N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W017443S1

L-Asparagine-amide-15N monohydrate	Endogenous Metabolite	Metabolic Disease
L-Asparagine-amide- ¹⁵N (monohydrate) is the ¹⁵N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0667S3

L-Asparagine-13C4 monohydrate (-)-Asparagine-¹³C₄ monohydrate; Asn-¹³C₄ monohydrate; Asparamide-¹³C₄ monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Asparagine- ¹³C₄ (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-E70074

Monoamine oxidase, plasma	Monoamine Oxidase	Neurological Disease
Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions .

HY-N0667S4

L-Asparagine-4-13C monohydrate (-)-Asparagine-4-¹³C monohydrate; Asn-4-¹³C monohydrate; Asparamide-4-¹³C monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Asparagine-4- ¹³C (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-B1730

Phensuximide 1 Publications Verification	Others	Neurological Disease Metabolic Disease
Phensuximide is an orally active succinimide antiepileptic and anticonvulsant agent. Phensuximide inhibits cyclic AMP and cyclic GMP accumulation in depolarized brain tissue. Phensuximide can be used for the study of seizure and petit mal .

HY-161835

SR140333B	Neurokinin Receptor	Inflammation/Immunology
SR140333B is a selective NK1 receptor inhibitor that can reduce LPS-induced fever and mitigate LPS (HY-D1056)-induced changes in brain tissue in rats .

HY-131006

FFN200 dihydrochloride	Monoamine Transporter	Neurological Disease
FFN200 dihydrochloride, a fluorescent substrate of VMAT2, selectively trace monoamine exocytosis in both neuronal cell culture and brain tissue. The fluorescence excitation and emission maxima of FFN200 are determined to be 352 and 451 nm, respectively .

HY-N0229S12

L-Alanine-d3 L-2-Aminopropionic acid-d₃	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-d₃ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S13

L-Alanine-d7 L-2-Aminopropionic acid-d₇	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-d₇ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S3

L-Alanine-d4 L-2-Aminopropionic acid-d₄	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-d₄ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-131891

JHU37152	mAChR	Neurological Disease
JHU37152 is a potent and brain-penetrant DREADD agonist, with EC₅₀s of 5 nM and 0.5 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37152 exhibits selective [ ³H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue .

HY-N0229S8

L-Alanine-13C3 L-2-Aminopropionic acid-¹³C₃	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹³C₃ is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S9

L-Alanine-13C2 L-2-Aminopropionic acid-¹³C₂	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹³C₂ is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-B0099R

Edaravone (Standard)	MMP Apoptosis	Neurological Disease
Edaravone (Standard) is the analytical standard of Edaravone. This product is intended for research and analytical applications. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator.

HY-131881

JHU37160 1 Publications Verification	mAChR	Neurological Disease
JHU37160 is a potent and brain-penetrant DREADD agonist, with EC₅₀s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [ ³H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue .

HY-N0229S1

L-Alanine-1-13C L-2-Aminopropionic acid-1-¹³C	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-1- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S2

L-Alanine-15N L-2-Aminopropionic acid-¹⁵N	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹⁵N is the ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[1].

HY-N0229S4

L-Alanine-13C,d1 L-2-Aminopropionic acid-¹³C,d₁	Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹³C,d is the ¹³C- and deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S6

L-Alanine-3-13C L-2-Aminopropionic acid-3-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-3- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S7

L-Alanine-2-13C L-2-Aminopropionic acid-2-¹³C	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-2- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-161759

MS152	Histone Methyltransferase	Metabolic Disease
MS152 is an oral bioactive inhibitor of EHMT2/G9a. MS152 reactivats maternally silenced Prader-Willi syndrome (PWS) genes in brain and liver tissues of PWS mouse models .

HY-N0667S1

L-Asparagine-15N2,d8	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Asparagine- ¹⁵N₂,d₈ is the ¹⁵N- and deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W017443S3

L-Asparagine-15N2,d3 monohydrate	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Asparagine- ¹⁵N₂,d₃ (monohydrate) is the deuterium and ¹⁵N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-D0001

Alcian Blue 8GX 4 Publications Verification	Fluorescent Dye	Others
Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues .

HY-N0229S16

L-Alanine-d3-1	Endogenous Metabolite	Metabolic Disease
L-Alanine-d₃-1 is the deuterium labeled L-Alanine[1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[2].

HY-W017443S4

L-Asparagine-1,2,3,4-13C4 monohydrate	Endogenous Metabolite	Metabolic Disease
L-Asparagine-1,2,3,4- ¹³C₄ (monohydrate) is the ¹³C labeled L-Asparagine (monohydrate)[1]. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-16923A

Crobenetine hydrochloride BIII-890 hydrochloride; BIII-890 CL	Sodium Channel	Neurological Disease
Crobenetine hydrochloride (BIII-890 hydrochloride) is the hydrochloride form of Crobenetine (HY-16923). Crobenetine hydrochloride is a selective inhibitor for Na ⁺ channel. Crobenetine hydrochloride displaces ^3HBTX from site 2 of the Na ⁺ channel (IC₅₀=49 nM) in rat brain synaptosomes, exhibits only low binding affinity for other receptors and ion channels. Crobenetine hydrochloride protects brain tissue from the deleterious effects of focal cerebral ischemia in rodents .

HY-W017443S

L-Asparagine-13C4,15N2 monohydrate	Endogenous Metabolite	Metabolic Disease
L-Asparagine- ¹³C₄, ¹⁵N₂ (monohydrate)is the ¹³C-labeled and ¹⁵N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S10

L-Alanine-13C3,15N L-2-Aminopropionic acid-¹³C₃,¹⁵N	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S14

L-Alanine-15N,d4 L-2-Aminopropionic acid-¹⁵N,d₄	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine- ¹⁵N,d₄ is the deuterium and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S15

L-Alanine-13C2,15N L-2-Aminopropionic acid-¹³C₂,¹⁵N	Endogenous Metabolite	Metabolic Disease
L-Alanine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S11

L-Alanine-1-13C,15N L-2-Aminopropionic acid-1-¹³C,¹⁵N	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease Metabolic Disease
L-Alanine-1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-W016145

L-Glutamic acid monosodium (hydrate)	Apoptosis	Metabolic Disease Cancer
L-Glutamic acid monosodium hydrate is a nutritional additive and flavoring agent. L-Glutamic acid monosodium hydrate can reduce obesity and induce metabolic disorders associated with oxidative stress. L-Glutamic acid monosodium hydrate induces oxidative stress,DNA damage and apoptosis in the liver and brain tissues of mice .

HY-NP019

Agkistrodon halys batroxobin	Sirtuin Caspase Apoptosis	Neurological Disease
Agkistrodon halys batroxobin is a thrombin-like serine protease. Agkistrodon halys batroxobin reduces the expression of Sirt1 and extracellular signal-regulated kinase activation in brain tissue. Agkistrodon halys batroxobin reduces cleaved caspase-3 expression and inhibits neuronal apoptosis in rat .

HY-149170

FFN246	5-HT Receptor Monoamine Transporter	Neurological Disease
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation .

Cat. No.	Product Name	Type

HY-D0001

Alcian Blue 8GX 4 Publications Verification	Dyes
Alcian Blue 8GX is a commonly used phthalocyanine dye that binds to glycoproteins and glycosaminoglycans. Alcian Blue 8GX has a wide range of applications in biological staining, including proteins in brain tumors and DNA in cells and tissues .

HY-W094758A

4-Di-1-ASP	Fluorescent Dyes/Probes
4-Di-1-ASP is a styryl dye used to stain glioma cells in living brain tissue for analysis of cell structure, viability, proliferation and endocytosis, cytokinesis and phagocytosis, as well as for observation of mitochondrial structures in living cells. 4-Di-1-ASP fluoresces green when imaged microscopically (λ_ex /λ_em = 475/606 nm) .

Cat. No.	Product Name	Type

HY-D0714

Tetrazolium Red

3 Publications Verification

2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC

Enzyme Substrates

Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .

HY-NP019

Agkistrodon halys batroxobin	Native Proteins
Agkistrodon halys batroxobin is a thrombin-like serine protease. Agkistrodon halys batroxobin reduces the expression of Sirt1 and extracellular signal-regulated kinase activation in brain tissue. Agkistrodon halys batroxobin reduces cleaved caspase-3 expression and inhibits neuronal apoptosis in rat .

Cat. No.	Product Name	Target	Research Area

HY-P10216

CAQK peptide	Peptides	Others
CAQK peptide selectively binds to injured mouse brain. CAQK peptide selectively targets demyelinating areas and it is absent from healthy tissue. The CAQK peptide target is a proteoglycan complex upregulated in brain injuries and is used for drug delivery. CAQK peptide can penetrate the blood-brain barrier .

HY-W013494

L-Carnosine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .

HY-P4052

Pinealon	ROS Kinase	Neurological Disease
Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon prevents reactive oxygen species (ROS) accumulation and suppresses the activation of ERK 1/2. Pinealon stimulates the functional activity of the main cellular elements of brain tissue, reduces the level of spontaneous cell death. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia .

HY-P3629

Dynorphin B 29 (pig) Leumorphin (pig)	Peptides	Neurological Disease Inflammation/Immunology
Dynorphin B 29 (Leumorphin) (pig) is a petide. Dynorphin B 29 (pig) can interact with multiple receptors in the brain, as well as in isolated tissue systems. Dynorphin B 29 (pig) can be used for the research of immunoreaction .

HY-P1557

Somatostatin-28 (1-12) 1-12-Somatostatin-28	Peptides	Neurological Disease
Somatostatin-28 (1-12) is a somatostatin fragment that is monitored in brain tissue to track processing of somatostatin.

HY-P2473

Neurogranin (48-76), human	Peptides	Neurological Disease
Neurogranin (48-76), human is a dominant endogenous peptide in Alzheimer's disease (AD) brain tissue. Neurogranin (48-76) is a potential biomarker for synaptic function in AD .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W017443

L-Asparagine monohydrate 3 Publications Verification	Structural Classification Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229

L-Alanine 1 Publications Verification Alanine	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Metabolic Disease Amino acids Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Disease markers Disease Research Fields Cancer	Endogenous Metabolite
L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0667

L-Asparagine 3 Publications Verification (-)-Asparagine; Asn; Asparamide	Structural Classification Neurological Disease Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity .

HY-B1614

Clenbuterol hydrochloride 3 Publications Verification NAB-365 hydrochloride	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Adrenergic Receptor
Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage .

HY-59291

Levacetylleucine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Amino Acid Derivatives
Levacetylleucine, an orally bioavailable and brain-penetrant endogenous metabolite, is an acetylated derivative of amino acid leucine. Levacetylleucine is the active form of N-acetyl-leucine (NAL). Levacetylleucine attenuates neuronal death and neuroinflammation in the cortical tissue of mice. Levacetylleucine also potentially improves ameliorates lysosomal and metabolic dysfunction. Levacetylleucine improves compensation of postural symptoms after unilateral chemical labyrinthectomy (UL) in rats. Levacetylleucine is promising for research of neurological manifestations of Niemann-Pick disease type C, traumatic brain injury and neurodegeneration prevention .

HY-17552

sn-Glycero-3-phosphocholine 1 Publications Verification Choline Alfoscerate; Alpha-GPC; L-α-GPC	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Cholinesterase (ChE) Endogenous Metabolite
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .

HY-B1189

Meglutol Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	HMG-CoA Reductase (HMGCR) Autophagy Endogenous Metabolite
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases .

HY-W013494

L-Carnosine 1 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Metabolic Disease Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cancer	Endogenous Metabolite
L-Carnosine is a dipeptide composed of beta-alanine and histidine. L-Carnosine is an endogenous metabolite found in human brain, muscle and gastrointestinal tissues and is present in all vertebrates. L-Carnosine is a non-enzymatic free radical scavenger and natural antioxidant with anti-inflammatory and neuroprotective properties that can inhibit biochemical changes associated with aging .

HY-W017443R

L-Asparagine monohydrate (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Asparagine (monohydrate) (Standard) is the analytical standard of L-Asparagine (monohydrate). This product is intended for research and analytical applications. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-B1614R

Clenbuterol (hydrochloride) (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Adrenergic Receptor
Clenbuterol (hydrochloride) (Standard) is the analytical standard of Clenbuterol (hydrochloride). This product is intended for research and analytical applications. Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage .

HY-E70007

Catechol O-methyltransferase, porcine liver COMT	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain .

HY-125337

SC4453	Triterpenes Structural Classification Animals Terpenoids Source classification	Na+/K+ ATPase
SC4453 is a digoxin analogue in which the lactone ring at C17β is replaced by a pyrazine ring. SC4453 is slightly inferior to digoxin in inhibiting (Na+ + K+)-ATPase, but shows similar sensitivity to potassium ions. The differences in the sensitivity of SC4453 to heart and brain tissue from different species are mainly due to differences in its dissociation rate from the receptor. These observations confirm the high sensitivity of the human heart to cardiac glycosides.

HY-N8931

Monomethyl lithospermate Lithospermic acid monomethyl ester	Structural Classification Labiatae Source classification Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants	Akt
Monomethyl lithospermate activates the PI3K/AKT pathway, which plays a protective role in nerve injury. Monomethyl lithospermate can improve the survival ability of SHSY-5Y cells, inhibit the breakdown of mitochondrial membrane potential (MMOP) and inhibit cell apoptosis. Monomethyl lithospermate also reduced the level of oxidative stress in the brain tissue of rats with middle artery occlusion (MCAO) and improved nerve damage in rats with ischemic stroke (IS) .

HY-N0667R

L-Asparagine (Standard)	Structural Classification Immune System Disorder Microorganisms Source classification Disease markers Amino acids Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder Cancer	Endogenous Metabolite
L-Asparagine (Standard) is the analytical standard of L-Asparagine. This product is intended for research and analytical applications. L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity . In Vitro:L-Asparagine (0.03 mM) can reverse the proliferation decline of six human cancer cells induced by ASNS siRNA knockdown . L-Asparagine (10 mM, 4 h) can stimulate ODC activity and proliferation in IPEC-J2 cells .

HY-N0229R

L-Alanine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Disease markers Amino acids Endogenous metabolite Cancer	Endogenous Metabolite
L-Alanine (Standard) is the analytical standard of L-Alanine. This product is intended for research and analytical applications. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. In Vitro: The viability of both hiPSCs, 201B7 cells and ehiPSCs decrease with an increase in L-Alanine concentration, and reach 7.5±1.3% and 3.7±0.7% respectively at 1.2 M of L-Alanine. On the other hand, no decrease in the viability of hFBs and hSkMCs are observed. Although the viability of iCMs slightly decreases along with the increase of the L-Alanine concentration, viability of iCMs at 1.2 M concentration of L-Alanine, 49.4±6.9%, is significantly higher than that of undifferentiated iPSCs, 201B7 cells and ehiPSCs (p< 0.01). The viability of hiPSCs, 201B7 cells and ehiPSCs, drastically decrease even after 2 or 4 h treatment. In contrast, the viability of hFBs fails to decrease at 1, 2, and 4 h and shows a small decrease at 24 h treatment. The viability of 201B7 cells in suspension culture decreases to 11.8±6.0% following treatment with 1.2 M L-Alanine for 2 h, whereas that of hFBs is 72.9±14.2% .

Cat. No.	Product Name	Chemical Structure

HY-N0667S5

L-Asparagine-d3 hydrate
L-Asparagine-d₃ (hydrate) is the deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0667S2

L-Asparagine-15N2 monohydrate
L-Asparagine- ¹⁵N₂ (monohydrate) is the ¹⁵N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W017443S1

L-Asparagine-amide-15N monohydrate
L-Asparagine-amide- ¹⁵N (monohydrate) is the ¹⁵N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S12

L-Alanine-d3
L-Alanine-d₃ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S13

L-Alanine-d7
L-Alanine-d₇ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S3

L-Alanine-d4
L-Alanine-d₄ is the deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S9

L-Alanine-13C2
L-Alanine- ¹³C₂ is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0667S3

L-Asparagine-13C4 monohydrate
L-Asparagine- ¹³C₄ (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0667S4

L-Asparagine-4-13C monohydrate
L-Asparagine-4- ¹³C (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S8

L-Alanine-13C3
L-Alanine- ¹³C₃ is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S1

L-Alanine-1-13C
L-Alanine-1- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S2

L-Alanine-15N
L-Alanine- ¹⁵N is the ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[1].

HY-N0229S4

L-Alanine-13C,d1
L-Alanine- ¹³C,d is the ¹³C- and deuterium labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S6

L-Alanine-3-13C
L-Alanine-3- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S7

L-Alanine-2-13C
L-Alanine-2- ¹³C is the ¹³C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0667S1

L-Asparagine-15N2,d8
L-Asparagine- ¹⁵N₂,d₈ is the ¹⁵N- and deuterium labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W017443S3

L-Asparagine-15N2,d3 monohydrate
L-Asparagine- ¹⁵N₂,d₃ (monohydrate) is the deuterium and ¹⁵N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S16

L-Alanine-d3-1
L-Alanine-d₃-1 is the deuterium labeled L-Alanine[1]. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[2].

HY-W017443S4

L-Asparagine-1,2,3,4-13C4 monohydrate
L-Asparagine-1,2,3,4- ¹³C₄ (monohydrate) is the ¹³C labeled L-Asparagine (monohydrate)[1]. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-W017443S

L-Asparagine-13C4,15N2 monohydrate
L-Asparagine- ¹³C₄, ¹⁵N₂ (monohydrate)is the ¹³C-labeled and ¹⁵N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S10

L-Alanine-13C3,15N
L-Alanine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S14

L-Alanine-15N,d4
L-Alanine- ¹⁵N,d₄ is the deuterium and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S15

L-Alanine-13C2,15N
L-Alanine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S11

L-Alanine-1-13C,15N
L-Alanine-1- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0229S

L-Alanine-2-13C,15N
L-Alanine-2- ¹³C, ¹⁵Nis the ¹³C-labeled and ¹⁵N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-W017443S2

L-Asparagine-13C4,15N2,d3 monohydrate
L-Asparagine- ¹³C₄, ¹⁵N₂,d₃ (monohydrate) is the deuterium, ¹³C-, and 15-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-N0229S5

L-Alanine-13C3,15N,d4
L-Alanine- ¹³C₃, ¹⁵N,d₄ is the deuterium, ¹³C-, and 15-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.

HY-N0667S

L-Asparagine-13C4,15N2,d8
L-Asparagine- ¹³C₄, ¹⁵N₂,d₈ is the ¹³C-labeled and ¹⁵N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-17552S

sn-Glycero-3-phosphocholine-d9

sn-Glycero-3-phosphocholine-d₉ is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

HY-122129S

Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d6

Dotriaconta-14,17,20,23,26,29-hexaenoic acid-d₆ is deuterium labeled Dotriaconta-14,17,20,23,26,29-hexaenoic acid. Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain. Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration. Dotriaconta-14,17,20,23,26,29-hexaenoic acid is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina .

Cat. No.	Product Name		Classification

HY-N0667

L-Asparagine 3 Publications Verification (-)-Asparagine; Asn; Asparamide		Freeze-drying Protective Agents Solubilizing Agents
L-Asparagine ((-)-Asparagine) is a non-essential amino acid involved in the metabolic control of nerve and brain tissue cell function. L-Asparagine has antitumor activity .

HY-147081

AS 1411 AGRO-100		Aptamers
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .

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