Search Result

Results for "

glucocorticoids receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Glucocorticoid Receptor (116) ADC Cytotoxin (14) ADC Linker (1) Androgen Receptor (6) Antibiotic (5) Antibody-Drug Conjugates (ADCs) (2) AP-1 (1) Apoptosis (8) Autophagy (7) Bacterial (5) Caspase (1) Complement System (5) Cytochrome P450 (2) Drug Metabolite (2) Drug-Linker Conjugates for ADC (10) Endogenous Metabolite (11) Enterovirus (2) Estrogen Receptor/ERR (4) Interleukin Related (1) LXR (2) Mineralocorticoid Receptor (3) Mitophagy (5) MMP (4) NF-κB (3) NO Synthase (5) Parasite (2) Phosphodiesterase (PDE) (2) PPAR (1) Progesterone Receptor (7) Reactive Oxygen Species (3) SARS-CoV (5) Target Protein Ligand-Linker Conjugates (1) TNF Receptor (4) Wnt (4) β-catenin (2)
By Research Areas:	Cancer (34) Cardiovascular Disease (11) Endocrinology (69) Infection (9) Inflammation/Immunology (89) Metabolic Disease (13) Neurological Disease (5)
Oligonucleotides:	Antisense Oligonucleotides (2)

139

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Targets Recommended: Glucocorticoid Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14234

Glucocorticoid receptor agonist 1 Publications Verification	Glucocorticoid Receptor	Metabolic Disease Inflammation/Immunology Endocrinology
Glucocorticoid receptor agonist is a Glucocorticoid receptor agonist that acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC₅₀ values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin .

HY-148435

Glucocorticoid receptor agonist-2	Glucocorticoid Receptor ADC Cytotoxin	Inflammation/Immunology
Glucocorticoid receptor agonist-2 (compound 21) is an **glucocorticoid receptor agonist with an IC₅₀** value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373 .

HY-152121

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Infection Inflammation/Immunology
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal is a **glucocorticoid receptor** agonist. Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used in anti-CD40 antibody agent conjugate (ADC). Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal can be used for the research of inflammation and immune regulation .

HY-49382

Fluocinolone acetonide 3-benzylaniline	Target Protein Ligand-Linker Conjugates	Others
Fluocinolone acetonide 3-benzylaniline (Precursor Example 1) is a glucocorticoid receptor agonist-linker conjugate, which can be used for the synthesis of anti-CD40 antibody-drug conjugates (ADCs) .

HY-120273

Glucocorticoids receptor agonist 3	Glucocorticoid Receptor	Metabolic Disease Inflammation/Immunology
Glucocorticoids receptor agonist 3 is a potent agonist of glucocorticoids receptor. Glucocorticoids receptor agonist 3 is useful to research diseases, such as obesity, diabetes, and inflammation (extracted from patent WO2000066522A1, compound 345) .

HY-139709

Glucocorticoids receptor agonist 1	Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoids receptor agonist 1 is a potent anti-inflammatory, arylpyrazole-based **glucocorticoid receptor** agonist that does not impair insulin secretion.

HY-139710

Glucocorticoids receptor agonist 2	Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoids receptor agonist 2 is a potent anti-inflammatory, arylpyrazole-based **glucocorticoid receptor** agonist that does not impair insulin secretion.

HY-400878

Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Cancer
Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal, a **glucocorticoid receptor agonist, is a drug-linker conjugate for ADC*. Glucocorticoid* receptor agonist-1 phosphate Gly-Glu-Mal can be used to synthesize the anti-CD40 antibody agent conjugates (WO2019106608A1; example 9) .

HY-W071581

Glucocorticoid receptor activator 1	Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR). Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research .

HY-120948

RU 45196	Others	Others
RU 45196 is an 11 beta-substituted 19-norsteroid of the estra-4,9-diene series. RU 45196 displays fluorescence properties (excitation at 480 nm, emission at 525 nm) as well as high binding affinities for the glucocorticoid and progesterone receptors .

HY-159695

IONIS-GCCRRx ISIS 426115	Glucocorticoid Receptor	Metabolic Disease
IONIS-GCCRRx (ISIS 426115), a **glucocorticoid receptor** antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) .

HY-159695A

IONIS-GCCRRx sodium ISIS 426115 sodium	Glucocorticoid Receptor	Metabolic Disease
IONIS-GCCRRx (ISIS 426115) sodium, a **glucocorticoid receptor** antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) .

HY-132811

Dazucorilant CORT113176	Glucocorticoid Receptor	Neurological Disease Inflammation/Immunology
Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a K_i value ＜1 nM in vitro. Dazucorilant can be used for the research of neurological disorders .

HY-125265

JTP-117968	Glucocorticoid Receptor	Metabolic Disease
JTP-117968, a novel selective **glucocorticoid receptor modulator (a non-steroidal SGRM, IC₅₀** of 6.8 nM), exhibits improved transrepression/transactivation dissociation .

HY-147293

Nenocorilant 1 Publications Verification	Glucocorticoid Receptor Apoptosis Caspase	Cancer
Nenocorilantis a potent, orally activity glucocorticoid receptor (GR) antagonist with K_i value of 0.15 nM. Nenocorilant has pro-apoptotic effects and improves potency combined with cytotoxic agent. Nenocorilant can be used for cancer research .

HY-N12744

2-O-trans-p-Coumaroylalphitolic acid	Glucocorticoid Receptor	Metabolic Disease
2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity .

HY-14648

Dexamethasone Maximum Cited Publications 164 Publications Verification Hexadecadrol; Prednisolone F	Glucocorticoid Receptor SARS-CoV Autophagy Complement System Mitophagy Bacterial Antibiotic ADC Cytotoxin	Infection Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist, apoptosis inducer, and common disease inducer in experimental animals, constructing models of muscle atrophy, hypertension, and depression. Dexamethasone can inhibit the production of inflammatory miRNA-155 exosomes in macrophages and significantly reduce the expression of inflammatory factors in neutrophils and monocytes. Dexamethasone also has potential for use in COVID-19 research .

HY-14648A

Dexamethasone acetate 4 Publications Verification Dexamethasone 21-acetate; Hexadecadrol acetate	Glucocorticoid Receptor Autophagy Mitophagy Bacterial SARS-CoV Antibiotic Complement System ADC Cytotoxin	Inflammation/Immunology Endocrinology Cancer
Dexamethasone acetate (Dexamethasone 21-acetate) is a **glucocorticoid receptor** agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.

HY-131543

22-Hydroxy mifepristone RU 42698	Endogenous Metabolite Glucocorticoid Receptor	Metabolic Disease
22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human **glucocorticoid receptor** is 48% .

HY-164860

Glucocorticoid receptor agonist-5	Glucocorticoid Receptor ADC Cytotoxin	Inflammation/Immunology
Glucocorticoid receptor agonist-5 (compound 4), a glucocorticoid molecule, is a potent **glucocorticoid receptor** agonist. Glucocorticoid receptor agonist-5 shows anti-inflammatory and immunosuppressive activity. Glucocorticoid receptor agonist-5 is used as an ADC Cytotoxin for antibody-drug conjugate .

HY-160177

Glucocorticoid receptor agonist-3	Glucocorticoid Receptor ADC Cytotoxin	Others
Glucocorticoid receptor agonist-3 (Preparation 6) is a glucocorticoid receptor agonist .

HY-149165

Glucocorticoid receptor modulator 2	Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoid receptor modulator 2 (Example 1) is a **glucocorticoid receptor modulator, with an IC₅₀** value less than 100 nM. Glucocorticoid receptor modulator 2 can be used for research of inflammatory and immune diseases .

HY-121131

Deacylcortivazol	Glucocorticoid Receptor	Endocrinology
Deacylcortivazol, a potent glucocorticoid, is a glucocorticoid receptor (GR) activator .

HY-161520

Glucocorticoid receptor/NF-κB modulator-1	Glucocorticoid Receptor NF-κB	Inflammation/Immunology
Glucocorticoid receptor/NF-κB modulator-1 (Compound 20) is a derivative of ocotillol. Glucocorticoid receptor/NF-κB modulator-1 suppresses the degradation of glucocorticoid receptor (GR) mRNA and GR protein, inhibits the activation of NF-κB signaling pathway. Glucocorticoid receptor/NF-κB modulator-1 downregulates levels of NO, interleukin-6 and tumor necrosis factor-alpha (TNF-α). Glucocorticoid receptor/NF-κB modulator-1 ameliorates sepsis in mouse model .

HY-163672

Glucocorticoid receptor modulator 3	Glucocorticoid Receptor	Metabolic Disease Inflammation/Immunology
Glucocorticoid receptor modulator 3 (Payload 6) is a thioester-containing **glucocorticoid receptor modulator (IC₅₀*=0.6 nM). Glucocorticoid* receptor modulator 3 is designed to inactivate unconjugated payloads rapidly through liver metabolism, thereby minimizing systemic exposure. Glucocorticoid receptor modulator 3 can be utilized in the development of antibody-drug conjugates (ADCs) targeting autoimmune diseases .

HY-137882

Glucocorticoid receptor agonist-1 Ala-Ala-Mal	Drug-Linker Conjugates for ADC Glucocorticoid Receptor	Inflammation/Immunology
Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88) is a glucocorticosteroid, and an agonist of **glucocorticoid receptor*. Glucocorticoid* receptor agonist-1 Ala-Ala-Mal can be conjugated with Adalimumab (HY-P9908) to prepare an ADC .

HY-163673

Glucocorticoid receptor modulator 4	Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor modulator 4 (Compound DL5) is a conjugate of a linker and a glucocorticoid receptor modulator. Glucocorticoid receptor modulator 4 exhibits GRE Reporter activity in mTNF expressing K562 cell with an EC₅₀ of 40 μM. Glucocorticoid receptor modulator 4 binds with an anti-tumor necrosis factor (TNF) antibody, and exhibits anti-inflammtory activity against arthritis in mouse models .

HY-160180

Glucocorticoid receptor agonist-4 Ala-Ala-Mal	TNF Receptor Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor agonist-4 Ala-Ala-Mal (Compound Preparation 9) is an anti-human TNFα antibody-glucocorticoid *receptor* agonist (GC) conjugate. Glucocorticoid receptor agonist-4 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases .

HY-160178

Glucocorticoid receptor agonist-3 Ala-Ala-Mal	TNF Receptor Glucocorticoid Receptor Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor agonist-3 Ala-Ala-Mal (Compound Preparation 8) is an anti-human TNFα antibody-glucocorticoid *receptor* agonist (GC) conjugate. Glucocorticoid receptor agonist-3 Ala-Ala-Mal can be used in the study of autoimmune and inflammatory diseases .

HY-131974

Glucocorticoid receptor agonist-1	Glucocorticoid Receptor ADC Cytotoxin	Inflammation/Immunology
Glucocorticoid receptor agonist-1 is a potent **glucocorticoid receptor agonist with an IC₅₀** of 2.8 nM extracted from patent WO2017210471A1, compound 41 .

HY-160179

Glucocorticoid receptor agonist-4	Glucocorticoid Receptor ADC Cytotoxin	Inflammation/Immunology
Glucocorticoid receptor agonist-4 (Compound Preparation 5) is a **glucocorticoid receptor** agonist that can be conjugated to TNF-α antibodies for the study of autoimmune and inflammatory diseases .

HY-142942

Glucocorticoid receptor-IN-2	Glucocorticoid Receptor MMP	Inflammation/Immunology
Glucocorticoid receptor-IN-2 (Compound WX019) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-2 exhibits very good transcriptional repressive activity with an IC₅₀ of 0.171 nM against hMMP1, and comparable transcriptional activation activity with an EC₅₀ of 0.94 nM against MMTV .

HY-142941

Glucocorticoid receptor-IN-1	Glucocorticoid Receptor MMP	Inflammation/Immunology
Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC₅₀ of 2.11 nM against hMMP1, and transcriptional activation activity with an EC₅₀ of 5.59 nM against MMTV .

HY-103548

GSK9027	Glucocorticoid Receptor	Endocrinology
GSK9027, as a non-steroidal glucocorticoid receptor (GR) agonist, behaves as a partial agonist on the 2×glucocorticoid response element (GRE) reporter system, and achieves intrinsic activities relative to dexamethasone .

HY-114154

AL-438	Glucocorticoid Receptor	Inflammation/Immunology
AL-438 is a potent, selective and orally active **glucocorticoid receptor modulator with K_i*s of 2.5, 1786, 53, 1440, >1000 nM for glucocorticoid* receptor, progesterone receptor, mineralocorticoid receptor, androgen receptor, estrogen receptor, respectively. AL-438 shows antiinflammatory activity .

HY-17461A

Cortisone acetate 2 Publications Verification Cortisone 21-acetate	Glucocorticoid Receptor Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-B1540

Beclometasone 3 Publications Verification Beclomethasone	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology Cancer
Beclometasone (Beclomethasone) is a prototype **glucocorticoid receptor** agonist.

HY-B1893

Fluorometholone 1 Publications Verification	Glucocorticoid Receptor	Inflammation/Immunology
Fluorometholone, a synthetic glucocorticoid, is a **glucocorticoid receptor** agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye .

HY-106365

Rofleponide	Others	Endocrinology
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models .

HY-139556

Zavacorilant	Glucocorticoid Receptor	Metabolic Disease
Zavacorilant is capable of modulating glucocorticoid receptor (GR) .

HY-148436

Glucocorticoid receptor agonist-2 Ala-Ala-Mal	Drug-Linker Conjugates for ADC	Inflammation/Immunology
Glucocorticoid receptor agonist-2 Ala-Ala-Mal (compound 79) can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference for ABBV-3373 .

HY-151876

Glucocorticoid receptor modulator 1	Glucocorticoid Receptor NF-κB AP-1	Inflammation/Immunology
Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective **glucocorticoid receptor modulator with an IC₅₀ value of 9 nM and 130 nM for NF-κB and AP-1*, respectively. Glucocorticoid* receptor modulator 1 can effectively reduce the expression of inflammatory factors IL-6, IL-1β, TNF-α, also can relieve dermatitis in mice .

HY-17461

Cortisone 3 Publications Verification 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E	Glucocorticoid Receptor Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Endocrinology
Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-14864

Mapracorat 1 Publications Verification ZK-245186; BOL-303242X	Glucocorticoid Receptor	Endocrinology
Mapracorat is a novel non-steroidal selective **glucocorticoid receptor** agonist.

HY-16722

Fosdagrocorat PF-04171327	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology
Fosdagrocorat (PF-04171327) is a dissociated **glucocorticoid receptor** agonist.

HY-14864A

(S)-Mapracorat (S)-ZK-245186; (S)-BOL-303242X	Glucocorticoid Receptor	Endocrinology
(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.

HY-B0248

Desonide 2 Publications Verification	Glucocorticoid Receptor	Inflammation/Immunology Endocrinology
Desonide is a non-fluorinated corticosteroid anti-inflammatory agent that acts on glucocorticoid receptors.

HY-157294

GSK866	Glucocorticoid Receptor	Cancer
GSK866 is a selective **glucocorticoid receptor agonist, with an IC₅₀** of 4.6 nM .

HY-17461AR

Cortisone acetate (Standard) 2 Publications Verification Cortisone 21-acetate (Standard)	Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Cortisone acetate (Standard) is the analytical standard of Cortisone acetate. This product is intended for research and analytical applications. Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-15709

AL 082D06 3 Publications Verification D06; D-06	Glucocorticoid Receptor	Endocrinology
AL 082D06 is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with K_i of 210 nM.

Cat. No.	Product Name	Type

HY-14648G

Dexamethasone (GMP) Hexadecadrol (GMP); Prednisolone F (GMP)	Fluorescent Dye
Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of **glucocorticoid receptor** .

Cat. No.	Product Name	Type

HY-14648G

Dexamethasone (GMP) Hexadecadrol (GMP); Prednisolone F (GMP)	Biochemical Assay Reagents
Dexamethasone (Hexadecadrol) (GMP) is Dexamethasone (HY-14648) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Dexamethasone is an agonist of **glucocorticoid receptor** .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17461A

Cortisone acetate 2 Publications Verification Cortisone 21-acetate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-17461

Cortisone 3 Publications Verification 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E	Structural Classification Microorganisms Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-17461AR

Cortisone acetate (Standard) 2 Publications Verification Cortisone 21-acetate (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortisone acetate (Standard) is the analytical standard of Cortisone acetate. This product is intended for research and analytical applications. Cortisone acetate (Cortisone 21-acetate), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acetate acts as an immunosuppressant and anti-inflammatory agent. Cortisone acetate can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-17461R

Cortisone (Standard) 3 Publications Verification 17-Hydroxy-11-dehydrocorticosterone(Standard); Kendall's compound E (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Glucocorticoid Receptor Endogenous Metabolite
Cortisone (Standard) is the analytical standard of Cortisone. This product is intended for research and analytical applications. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to *Glucocorticoid-receptor* at high concentrations .

HY-B0469

Medroxyprogesterone acetate Maximum Cited Publications 20 Publications Verification Medroxyprogesterone 17-acetate; Farlutin	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and **glucocorticoid receptors** .

HY-B0469R

Medroxyprogesterone acetate (Standard) Maximum Cited Publications 20 Publications Verification Medroxyprogesterone 17-acetate(Standard); Farlutin (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite
Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and **glucocorticoid receptors** .

HY-N0835

(20S)-Protopanaxatriol 20(S)-APPT; g-PPT	Panax ginseng C. A. Meyer Cardiovascular Disease Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Araliaceae	Glucocorticoid Receptor Estrogen Receptor/ERR LXR Apoptosis
(20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and *estrogen receptor* (ER), and is also a LXRα** inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects .

HY-B0328

Triamcinolone 2 Publications Verification	Classification of Application Fields Source classification Solanum lyratum Thunberg Solanaceae Plants Inflammation/Immunology Disease Research Fields Steroids Cancer	Glucocorticoid Receptor Interleukin Related
Triamcinolone is a long-acting corticosteroid with anti-inflammatory, anti-oedematous, anti-proliferative, anti-angiogenetic, immunomodulatory and neuroprotective effects through binding to **glucocorticoid receptors**. Triamcinolone can relieve several dermatitis, immune diseases and ocular diseases .

HY-N12744

2-O-trans-p-Coumaroylalphitolic acid	Triterpenes Structural Classification Terpenoids Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chow. Source classification Plants Rhamnaceae	Glucocorticoid Receptor
2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity .

HY-B0154R

Fluticasone (propionate) (Standard)	Structural Classification Source classification Steroids	Glucocorticoid Receptor Enterovirus Endogenous Metabolite ADC Cytotoxin
Fluticasone (propionate) (Standard) is the analytical standard of Fluticasone (propionate). This product is intended for research and analytical applications. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity .

HY-N0835R

(20S)-Protopanaxatriol (Standard)	Panax ginseng C. A. Meyer Triterpenes Structural Classification Terpenoids Source classification Plants Araliaceae	Glucocorticoid Receptor Estrogen Receptor/ERR LXR Apoptosis
(20S)-Protopanaxatriol (Standard) is the analytical standard of (20S)-Protopanaxatriol. This product is intended for research and analytical applications. (20S)-Protopanaxatriol is a metabolite of ginsenoside. (20S)-Protopanaxatriol works through the glucocorticoid receptor (GR) and estrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows a broad spectrum of antitumor effects .

Cat. No.	Product Name	Chemical Structure

HY-17461S

Cortisone-13C3
Cortisone- ¹³C₃ is the ¹³C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].

Cat. No.	Product Name		Classification

HY-159695

IONIS-GCCRRx ISIS 426115		Antisense Oligonucleotides
IONIS-GCCRRx (ISIS 426115), a **glucocorticoid receptor** antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) .

HY-159695A

IONIS-GCCRRx sodium ISIS 426115 sodium		Antisense Oligonucleotides
IONIS-GCCRRx (ISIS 426115) sodium, a **glucocorticoid receptor** antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO) .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

glucocorticoids receptor

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products